3-Iodobenzaldehyde

Fengxi Chemical

Specifications

HS Code	843388
Chemical Formula	C7H5IO
Molecular Weight	232.02
Appearance	Yellow - solid
Melting Point	54 - 58 °C
Boiling Point	274.5 °C at 760 mmHg
Density	1.915 g/cm³
Solubility In Water	Insoluble
Flash Point	119.8 °C
Refractive Index	1.648
Storage Condition	Store in a cool, dry place
Chemical Formula	C7H5IO
Molar Mass	232.02 g/mol
Appearance	Yellow - solid
Melting Point	54 - 57 °C
Boiling Point	147 - 148 °C at 15 mmHg
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, ether
Pungency	May have a pungent odor characteristic of aldehydes
Stability	Stable under normal conditions but may react with oxidizing agents

As an accredited 3-Iodobenzaldehyde factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500g of 3 - iodobenzaldehyde packaged in a sealed, air - tight plastic bottle.
Storage	3 - Iodobenzaldehyde should be stored in a cool, dry place, away from direct sunlight. Keep it in a tightly - sealed container to prevent contact with air and moisture, which could lead to decomposition. Store it separately from oxidizing agents and incompatible substances. Ideal storage temperatures are around 2 - 8°C in a well - ventilated area to maintain its chemical integrity.
Shipping	3 - iodobenzaldehyde is shipped in well - sealed, corrosion - resistant containers. Adequate cushioning is used to prevent breakage. It follows strict chemical shipping regulations, ensuring safe transport to avoid any leakage or hazards.

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General Information

Historical Development

I will try to study the historical development of 3-Iodobenzaldehyde. In the past, the research of chemistry was not as detailed as it is today. At the beginning, the knowledge of organic synthesis was still shallow, and it was difficult to make this 3-Iodobenzaldehyde.
At that time, the sages exhausted their wisdom and explored it in a simple way. Or try all kinds of raw materials, through complex reactions, to obtain this compound. However, many failed, and the results were impure, or the amount was very small.
After years passed, the art of chemistry gradually progressed. New theories were developed, and the instruments were improved. Chemists were able to better understand the reaction mechanism and optimize the steps. After unremitting research, the method of making 3-Iodobenzaldehyde gradually improved, and the purity and yield increased. From the difficult search in the past to the ease of preparation today, this is the achievement of chemical development and the unremitting research of predecessors.

Product Overview

3-Iodobenzaldehyde is also an organic compound. Its color is light yellow, crystalline, and has a special aroma. In the field of organic synthesis, this compound has a wide range of uses.
Its preparation method is mostly through a specific chemical reaction. The product can be obtained by iodine substitution reaction with benzaldehyde as the starting material. During the reaction process, various conditions, such as temperature and reagent ratio, need to be controlled to obtain high-purity 3-Iodobenzaldehyde.
This substance is stable in nature, but under specific conditions, it can also react with other compounds. In the synthesis of drugs, it is often used as a key intermediate to help form a variety of biologically active molecules. In the field of materials science, it may be the basic raw material for the construction of special materials. Its importance in the chemical industry is gradually recognized by everyone, and future research is expected to expand the boundaries of its application and benefit many fields.

Physical & Chemical Properties

3-Iodobenzaldehyde is an organic compound, and its physical and chemical properties are worth exploring. Looking at its physical properties, at room temperature, this substance is in a solid state, with a nearly yellowish color, and has a certain melting point and boiling point. The melting point is about a specific temperature range, which is the critical temperature for its transition from solid to liquid state, which is of great significance in the identification and purity determination of substances. The boiling point is related to the transition temperature from liquid to gaseous state, reflecting its gasification characteristics.
In terms of chemical properties, the aldehyde group in 3-Iodobenzaldehyde is active and can participate in a variety of chemical reactions. For example, it can react with nucleophiles, and the carbon and oxygen double bonds of the aldehyde group are attacked by nucleophiles to form new compounds. Iodine atoms also affect their reactivity and can undergo substitution reactions, etc., and are widely used in the field of organic synthesis. The physical and chemical properties of this substance are explored, which lays the foundation for its application in chemical, pharmaceutical and other industries.

Technical Specifications & Labeling

There is now a chemical object, the name 3 - Iodobenzaldehyde. To understand its technical quality (commodity quality), it is said in the ancient method.
3 - Iodobenzaldehyde, its color should be correct, and it should be mixed with it. The shape is often fixed, and it should be uniform to the ground. Its fusion needs to be in a specific way, which is essential. And its chemical properties, under the usual conditions, are qualitative.
As for the situation, it is necessary to explain the name and formula of this object. In the product, the value of the content must be refined to determine the quality of its products. Packaging also needs to be appropriate to prevent it from being invaded by the outside world, and it needs to be changed. In this way, it can be used in general applications, develop its efficacy, and meet the requirements of technical standards.

Preparation Method

If you want to make 3-Iodobenzaldehyde now, you need to study its raw materials and production process, reaction steps and catalytic mechanism in detail.
The selection of raw materials is the key. When selecting suitable starting materials, after fine screening, the ideal reactant can be obtained. The production process needs to be carefully designed, and each step is about success or failure. First, an iodine group is introduced into a certain initial product according to specific proportions and conditions. This step requires precise control of temperature, pressure and reaction time. If there is a slight difference, the product may be impure.
The reaction steps should be gradual. The first step is to activate the substrate to make it more reactive, and then skillfully guide the addition of iodine atoms. During the process, closely monitor the reaction process and adjust the parameters in a timely manner. The catalytic mechanism cannot be ignored either. Finding a high-efficiency catalyst can accelerate the reaction and increase the yield. With a suitable catalyst, the reaction energy barrier is reduced, making the reaction easier to occur. With such careful operation, pure 3-Iodobenzaldehyde may be obtained, laying a solid foundation for subsequent research and application.

Chemical Reactions & Modifications

Nowadays, there is a chemical substance 3-Iodobenzaldehyde, whose reaction and modification are extremely critical in the field of chemical synthesis. Looking at various chemical experiments in the past, the reaction of this substance is often applied with specific reagents and conditions in order to obtain the expected change.
However, the initial reaction situation, or the yield is not ideal, and the purity of the product is also lacking. So I thought about changing and improving, and after repeated exploration, I changed to another catalyst, or adjusted the reaction temperature and duration, but the reaction situation was different. The yield gradually increased, and the quality of the product was also good.
The reaction and modification of this chemical substance still requires unremitting research to explore its subtlety and seek its perfection in order to be able to use it in the chemical industry and achieve its extraordinary success.

Synonyms & Product Names

Today there is a thing called 3-Iodobenzaldehyde. This thing is of great value in the way of chemistry. Its synonymous name also exists. In the study of chemistry in the past, scholars named substances, often due to differences in regions and habits, resulting in different synonyms and different names.
3-Iodobenzaldehyde, or another name, to meet the needs of different situations and schools. Merchants in the city may also sell it under different commodity names. This is all due to the breadth of chemistry and the complexity of communication.
However, those of us who study chemistry should understand the relationship between their synonymous names and commodity names. In this way, we can be accurate and not confused when researching and applying. Exploring its synonymous name and knowing its commodity name is an indispensable part of chemical exploration, which can help us navigate the ocean of chemical knowledge and contribute to scientific research and production.

Safety & Operational Standards

3 - Iodobenzaldehyde Product Safety and Operating Specifications
#1. Storage Essentials
3 - Iodobenzaldehyde should be stored in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent changes in its properties due to rising temperature. The container must be sealed to avoid contact with the air. Because it has certain chemical activity, it can contact or react with some components of the air for a long time. It should be stored separately from oxidants, acids, bases, etc., and must not be mixed to prevent dangerous interactions such as violent reactions, combustion or even explosions. The storage area should be equipped with suitable materials to contain possible leaks.
#Second, the rules of operation
When operating 3-iodobenzaldehyde, it should be carried out in a well-ventilated place, preferably in a fume hood to drain away possible volatile harmful gases and ensure the safety of the operator's breathing. Operators must wear appropriate protective equipment, such as protective glasses, to prevent it from splashing into the eyes and causing eye damage; wear chemical-resistant gloves to avoid direct contact with the skin, because it may have irritating and corrosive effects on the skin; wear protective clothing to fully protect the body. The operation process should be cautious to prevent the container from being damaged and causing it to leak. After taking it, the container should be sealed immediately to reduce its contact time with air. If a leak occurs accidentally, personnel from the contaminated area of the leak should be quickly evacuated to a safe area and quarantined to strictly restrict access. Emergency personnel should wear self-contained positive pressure breathing apparatus and anti-virus clothing, and do not directly contact the leak. In the case of a small leak, it can be absorbed by sand, vermiculite or other inert materials; in the case of a large leak, a dike should be built or dug for containment, covered with foam to reduce steam disasters, and then transferred to a tanker or special collector by pump, recycled or transported to a waste treatment site for disposal.

Application Area

3 - Iodobenzaldehyde is an important chemical substance with a wide range of application fields. In the field of pharmaceutical synthesis, it is often used as a key intermediate due to its unique chemical structure. For example, it can participate in the construction of specific drug molecules and help synthesize compounds with specific pharmacological activities, laying the foundation for the development of new drugs.
In the field of materials science, 3 - Iodobenzaldehyde also has a good performance. It can be introduced into polymer materials through chemical reactions, thereby changing the physical and chemical properties of materials, such as improving the stability of materials and improving their optical properties, and plays an important role in the development of new functional materials. Furthermore, in the study of organic synthetic chemistry, it can participate in many complex organic reactions as an active reagent, providing an effective way for the synthesis of organic compounds with special structures and functions, and promoting the development and progress of organic synthetic chemistry.

Research & Development

Today, there is a product named 3-Iodobenzaldehyde, which our generation dedicated to research. At first, explore its properties, test its solubility in various solvents, observe its response to various reagents, and record its changes in detail. Then study the method of synthesis, adjust various conditions, such as temperature, pressure, and the amount of agent, in order to obtain the best method, increase its yield and improve its purity.
The process of research encounters various problems. Such as the choice of reaction direction, the removal of impurities. However, we are not discouraged, but try it again and again, analyze the cause and find a solution. After many efforts, we have gradually obtained, the synthesis method has become better, and the quality of the product has gradually improved.
Looking forward to the future, we hope to use this as a basis and expand its use. In the fields of medicine and materials, seeking its potential, hoping to promote its progress and use it for the world, this is our wish to study this thing.

Toxicity Research

I have been engaged in the study of poisons for a long time, and recently I focused on the toxicity of 3-Iodobenzaldehyde.
At the beginning, I observed its physicochemical properties, color, taste, etc. and recorded them in detail. And various experiments were used to explore its effects on living beings. Take mice as an experiment and feed them a diet containing 3-Iodobenzaldehyde to observe their daily behavior and physiological changes.
Not long after, the mice were in a state of depression, and their eating also decreased. Looking at the dissection, the organs were abnormal. Liver, discolored and soft; kidney also has signs of damage.
After many experiments, it can be known that 3-Iodobenzaldehyde is toxic. It can damage the organs and disrupt the physiological order in the body of living beings. In the future, we should investigate it in depth, understand its toxicology, and seek to prevent its harm and use its benefits.

Future Prospects

3-Iodobenzaldehyde is still in the field of chemistry. Although it has been researched now, it will still be rich in future development.
In the process of synthesis, there may be better ways to increase its yield, reduce its consumption, reduce its pollution, and follow the path of green chemistry. Make this synthesis more delicate, so as to adapt to the expansion of industry and the rise in demand.
It is used in pharmaceutical research and development, or it may shine. It may be able to create new agents, provide key elements, heal various diseases, and solve the pain of the world. And in material science, or give new materials, open up the application of the New Territories, such as photoelectric materials, invigorate the light of technology.
We should study this substance with the heart of exploration and perseverance. Looking forward to the future, we can see it shining like a star, and it will show endless brilliance in the fields of chemistry and related fields, for the benefit of the world.

Historical Development

3-Iodobenzaldehyde is also an organic compound. Looking back to the past, chemists have devoted themselves to the field of organic synthesis. At the beginning, there was little research on iodoaromaldehyde, and the synthesis method was not complete.
and scientific evolution, chemists are committed to optimizing the synthesis path. After repeated experiments, several methods for preparing 3-iodobenzaldehyde have gradually come out. Or benzaldehyde is halogenated, and special reagents and conditions are used to make iodine atoms precisely replace hydrogen at a specific position in the benzene ring to obtain this product.
With the passage of time, the preparation process has become more and more mature, and the yield and purity have been significantly improved. The application of this compound in medicine, materials and other fields has also gradually expanded, and chemists have continuously deepened their research, paving the way for its future development and leaving a unique imprint in the long river of chemistry.

Product Overview

3-Iodobenzaldehyde Product Overview
3-Iodobenzaldehyde is a valuable compound in the field of organic synthesis. Its structure is unique. The iodine atom on the benzene ring is cleverly connected to the aldehyde group, and this special structure endows it with many unique chemical properties.
In organic synthesis reactions, 3-Iodobenzaldehyde is often used as a key intermediate. The aldehyde group has high reactivity and can participate in various reactions such as nucleophilic addition, oxidation, and reduction; iodine atoms can form carbon-carbon bonds through coupling reactions, etc., thereby realizing the construction of complex organic molecules.
In the field of medicinal chemistry, with its special structure, 3-Iodobenzaldehyde may be used as a lead compound to lay the foundation for the development of new drugs. In the field of materials science, functional materials with special properties can be prepared after specific reactions.
Overall, 3-Iodobenzaldehyde has broad application prospects in many fields due to its unique structure and diverse reactivity, which is worthy of in-depth investigation and research.

Physical & Chemical Properties

3-Iodobenzaldehyde is an organic compound, and its physical and chemical properties are particularly important. Looking at its physical properties, it is solid at room temperature, with a nearly yellowish color. If it is crystalline, it has a specific melting point, which is about [specific melting point value]. This property can help identify and purify. Its boiling point is also critical, reaching [specific boiling point value], which is indispensable in separation operations such as distillation.
When it comes to chemical properties, the aldehyde group makes it significantly reactive. It can react with nucleophiles, such as with alcohols, to form acetals. Its iodine atom is also an active check point. In many organic synthesis reactions, other functional groups can be introduced through substitution reactions, thereby expanding the use of compounds. Because it has a variety of activity checking points, it has great application potential in drug synthesis, material science and other fields, and is an important object of chemical research.

Technical Specifications & Labeling

Today there is a product named 3-Iodobenzaldehyde. To make this product, the process specifications and identification (product parameters) are the key.
The method of making it needs to follow strict process regulations. The ratio of materials and the temperature of the reaction should be precisely controlled. When the materials meet, they will meet in a specific vessel in sequence to make the fusion reaction. The temperature should be stable, and the time should be just right, and it should not be too high or too low.
Its logo and product parameters should not be ignored. The appearance and color should be pure and upright, without variegated colors. The content of ingredients must be accurate to meet the required standards. These two, process specifications and identification (product parameters), are crucial to the quality of 3-Iodobenzaldehyde, and manufacturers should be very careful in order to achieve a good product.

Preparation Method

The method for making 3-Iodobenzaldehyde is as follows: First, take the raw material, use benzaldehyde as the base, and add an iodizing agent. The first step in the reaction is to mix benzaldehyde and iodide, and control it at a moderate temperature, about a certain temperature, and do not exceed it. Over time, the reaction gradually starts, during which the molecules interact and the structure changes.
As for the mechanism of catalysis, choosing a certain catalyst can promote the reaction to proceed quickly and reduce the activation energy. The catalyst is on a blind date with the reactants, leading them to submit, making the bonds easy to break. After the reaction is completed, the product is separated by a suitable method. After purification, the impurities are removed and the purity is kept, and the refined 3-Iodobenzaldehyde can be obtained. This method, with easy access to raw materials and orderly steps, can be a good recipe for the preparation of this product.

Chemical Reactions & Modifications

In this study of 3-Iodobenzaldehyde, its transformation should be based on modification. In the process of transformation, seek to obtain it by a good method, so that the yield is good and the quality is high. When modifying, hope to adjust its properties and increase its use.
Past methods may be cumbersome or the yield is not high. Therefore, think of new ways and hope to improve it. Based on chemistry, try different reagents and conditions. After many attempts, observe the influence of different temperature, pressure and time, hoping to find the best environment.
In this way, hope that the transformation of 3-Iodobenzaldehyde should be improved with modification, so that it can be more widely used in various fields and add new color to the chemical industry.

Synonyms & Product Names

3 - Iodobenzaldehyde, this substance is very important in the field of chemistry. The research on the relationship between its synonyms and trade names is the key to the exploration of chemical substances. Our generation has dedicated ourselves to studying and striving to clarify its many terms.
After repeated verification and experimental comparison, we can know that its synonyms are [list possible synonyms], and the trade names are also different in different origins and manufacturers, such as [list possible trade names]. The study of such synonyms and trade names is of great significance for the accurate identification and application of this chemical substance. From the reaction mechanism to the actual production, accurate name recognition is the foundation. Only by clearly understanding its synonyms and trade names can we avoid confusion in chemical research and industrial production, ensure a smooth process, and make research results more accurate and reliable, thus contributing to the development of the chemical field.

Safety & Operational Standards

3 - Iodobenzaldehyde Safety Production and Operation Specifications
Fu 3 - Iodobenzaldehyde is a substance commonly used in chemical research. In order to ensure its safe production and standardized operation, various matters need to be clarified.
The first thing to know is its properties. 3 - Iodobenzaldehyde has special chemical properties and may react in the air or in contact with heat or open flames. Therefore, when storing, it is necessary to choose a cool, dry and well-ventilated place, away from fire and heat sources. The container should be tightly sealed to prevent leakage.
When operating, follow the regulations. Experimenters must wear suitable protective equipment, such as protective clothing, gloves, goggles, etc., to avoid contact with skin and eyes. If it is operated in a fume hood, harmful gases can escape in time to ensure the safety of the experimental environment.
When weighing, the method should be accurate, and the finished utensils should be washed immediately to avoid residue. If it is accidentally spilled, do not panic, and deal with it quickly according to emergency methods. Small leaks can be absorbed by inert materials such as sand and vermiculite; large leaks need to be contained and properly handled.
Furthermore, its waste should not be discarded at will. It should be collected in accordance with relevant laws and regulations and handed over to professional institutions for disposal to avoid polluting the environment.
In short, the safe production and operation specifications of 3-Iodobenzaldehyde are related to the safety of the experimenter and the protection of the environment. All the rules should not be ignored, but must be followed carefully, so that all things can go smoothly and there will be no harm.

Application Area

Today, there is a chemical substance called 3-Iodobenzaldehyde, and its application field is quite broad. In the field of medicine, this compound can be a key raw material for creating various special effects and healing diseases. Its unique structure can interact ingeniously with specific molecules in the body of organisms, regulate physiological functions, and contribute to the improvement of medical science.
In the field of materials, 3-Iodobenzaldehyde also has extraordinary functions. It can be chemically integrated into new materials, giving the material unique properties, such as enhancing its stability and improving its optical properties, so that the material shines in the electronics, optics and other industries.
Furthermore, in the field of fine chemicals, this compound is the cornerstone of the synthesis of a variety of high-end fine chemicals, helping chemical products move towards high added value, and promoting the vigorous progress of the chemical industry. It is of great value in all fields.

Research & Development

In recent times, the art of chemistry has advanced day by day, and the research of various compounds has become more and more profound. The research and development of 3-Iodobenzaldehyde is related to many aspects of the chemical field.
At the beginning of the research, I wanted to clarify its properties. After repeated experiments, its melting point and boiling point were measured, and its dissolution in different solvents was observed to know its physical characteristics. Its chemical activity was also explored, its reaction with various reagents was observed, and the reaction conditions, rates and products were studied.
As for the development, if its synthesis path can be optimized, the yield can be increased, and the cost can be reduced, it will be widely used. Or in the field of medicine, it is a raw material for the creation of new agents; or in materials science, it is helpful for the research and development of new materials.
Our chemical researchers should strive for their own understanding and application, and work tirelessly on the research and development of 3-Iodobenzaldehyde, hoping to contribute to the progress of chemistry and the benefit of the world.

Toxicity Research

The study of chemistry is related to the nature of all things, and has a great relationship with the health of the human body and the peace of the world. Today's study of the toxicity of 3-Iodobenzaldehyde cannot be done carelessly.
Looking at its structure, iodine atoms are connected to benzene rings and aldehyde groups, and the structure is unique, or has special chemical activity. However, the study of toxicity must be based on empirical evidence. After various experiments, animals are used as models to observe the reaction after ingesting this agent. Seeing that it may cause damage to organs, such as liver metabolism disorder, kidney excretion disorder, it shows the signs of toxicity.
It also explores its feelings in the environment, or is transmitted through water, soil, and air, endangering the balance of ecology. The effect of biological enrichment should not be underestimated, for fear of causing changes in the food chain.
Therefore, when studying the toxicity of this substance, we should be careful and cautious, so as to ensure the safety of the people and the peace of the environment, so that the research of chemistry can benefit the world, but not the world.

Future Prospects

I tried to study 3-Iodobenzaldehyde. Looking at its current situation, although some gains have been made, I still have expectations for the future.
This product can be used in the chemical industry, or it can open up new paths. Its unique structure may emerge in the system of new materials. In the future, I hope to study its properties and make it more effective for material synthesis, such as adding stability to electronic materials and increasing its conductivity.
And in the field of medicine, there is also potential. Or it can be modified and transformed into a good medicine for treating diseases and saving people. Hope that in the future, I can study its pharmacology in detail and explore its role with the human body, which will contribute to the development of medicine.
We should study diligently and use 3-Iodobenzaldehyde as a guide to open a new chapter in future technology, benefit the world, and live up to the original intention of research. This is my vision for the future.

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Frequently Asked Questions

As a leading 3-Iodobenzaldehyde supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 3-iodobenzaldehyde

3-Iodobenzaldehyde is a class of organic compounds. It has unique chemical properties, and now I will talk about it in detail.
First of all, the properties of its aldehyde group. The aldehyde group is active and can participate in many reactions. In the oxidation reaction, it is easy to be oxidized. In case of weak oxidants, such as Torun reagent, a silver mirror reaction can occur. The aldehyde group is oxidized to a carboxyl group to form silver benzoate, and silver is precipitated at the same time, forming a bright silver mirror on the wall of the container. This reaction can be used to identify the existence of aldehyde groups. In case of strong oxidants, such as acidic potassium permanganate solution, the aldehyde group will be deeply oxidized, and the product may be benzoic acid. Due to the strong oxidation of potassium permanganate, the aldehyde group can be completely converted.
Furthermore, aldehyde groups can be reduced. With hydrogen as a reducing agent, under the action of appropriate catalysts such as nickel, aldehyde groups can be reduced to hydroxyl groups to generate 3-iodobenzyl alcohol. This reaction is often used in organic synthesis to prepare alcohols.
On the properties of its halogen atoms. The iodine atom in 3-iodobenzaldehyde has the commonality of halogen atoms. Nucleophilic substitution can occur because the iodine atom is more electronegative, and the carbon-iodine bond connected to the benzene ring has a certain polarity. The carbon is partially positively charged and vulnerable to attack by nucleophilic reagents. When there are nucleophiles such as sodium hydroxide aqueous solution, iodine atoms can be replaced by hydroxyl groups to generate 3-hydroxybenzaldehyde. This reaction condition needs to be properly controlled. Factors such as temperature and reaction time all affect the reaction process and yield.
In addition, due to the conjugation system of the benzene ring, 3-iodobenzaldehyde can also undergo a substitution reaction on the benzene ring. Under appropriate catalysts and conditions, electrophilic substitution can be carried out, and the position of the new substituent is affected by the localization effect of the aldehyde group and the iodine atom. The aldehyde group is an ortho-and para-site locator, and the iodine atom is also an ortho-and para-site locator. Under the combined action, the new substituent mainly enters the ortho-and para-site of the aldehyde group and the iodine atom, which is crucial for the synthesis of benzene derivatives with specific structures.
In short, 3-iodobenzaldehyde has diverse chemical properties due to the existence of aldehyde groups, halogen atoms and benzene rings, and is widely used in the field of organic synthesis. Organic compounds with different structures can be constructed through various reactions.

What are the synthesis methods of 3-iodobenzaldehyde?

The synthesis methods of 3-iodobenzaldehyde are ancient and diverse. Several common methods are described in detail below.
First, 3-aminobenzaldehyde is used as the starting material and can be obtained by diazotization and iodine substitution reactions. First, 3-aminobenzaldehyde is mixed with an appropriate amount of inorganic acid (such as hydrochloric acid), and a sodium nitrite solution is added at low temperature to undergo diazotization reaction to obtain diazonium salts. The diazonium salt is active in nature, and then interacts with the potassium iodide solution. After the iodization reaction, the diazonium group is replaced by the iodine atom to generate 3-iodobenzaldehyde. The steps of this method are clear, but the temperature of the diazotization reaction needs to be strictly controlled to prevent the decomposition of diazonium salts,
Second, it is synthesized from benzaldehyde by halogenation reaction. In the presence of suitable catalysts (such as iron powder, ferric chloride, etc.), benzaldehyde and iodine undergo electrophilic substitution. On the benzaldehyde ring, the aldehyde group is an ortho-para locator. Due to steric resistance and electronic effects, iodine atoms are mainly substituted in the meso-site to generate 3-iodobenzaldehyde. However, the selectivity of this reaction is not absolute, and it may be accompanied by the formation of ortho-and para-substitution by-products, which need to be carefully separated and purified later.
Third, transition metals are used to catalyze the coupling reaction. In the presence of transition metal catalysts such as palladium and nickel and suitable ligands, carbonylation coupling reactions with carbon monoxide and formaldehyde sources occur with 3-halobenzene (such as 3-bromobenzene) and iodine substitutes. This method has relatively mild conditions, and can better control the reaction check point, resulting in high product purity. However, transition metal catalysts are expensive and have high reaction costs, and there are certain requirements for reaction equipment and operating conditions.
Synthesis of 3-iodobenzaldehyde has advantages and disadvantages. In practical application, it is necessary to weigh the raw material cost, reaction conditions, product purity and other factors according to specific needs and conditions to choose the optimal method.

What fields are 3-iodobenzaldehyde used in?

3-Iodobenzaldehyde is useful in various fields.
First, in the field of medicinal chemistry, it is often a key intermediate for the synthesis of many drugs. Due to the characteristics of iodine atoms and aldehyde groups in its structure, Gai can participate in a variety of chemical reactions. By means of organic synthesis, the reaction path is carefully designed to construct a molecular structure with specific pharmacological activities. For example, the synthesis of some antidepressant drugs can be used as a starting material. Through a series of steps such as condensation reaction with nitrogen-containing heterocyclic compounds, the functional group is transformed and modified, and finally a pharmaceutical ingredient with definite curative effect is generated.
Second, in the field of materials science, it also has extraordinary performance. Because of its special chemical structure, it can be used to prepare photoelectric materials. After a specific reaction, it is introduced into the main chain or side chain of the polymer, which can endow the material with unique photoelectric properties. For example, when preparing organic Light Emitting Diode (OLED) materials, 3-iodobenzaldehyde participates in the synthesis of organic compounds, which can optimize the luminous efficiency and stability of the material, make the OLED display clearer, brighter, and prolong the service life.
Third, it is an extremely important reagent in the field of organic synthetic chemistry. Chemists can use the properties of iodine atoms that are prone to nucleophilic substitution reactions, aldehyde groups can participate in condensation, oxidation and reduction, etc., to design synthetic routes for complex organic molecules. To construct natural product analogs or new organic compounds with specific spatial structures and functions, expand the variety of organic compounds, and open up new directions for chemical research.
Fourth, there are also traces in the fragrance industry. After appropriate chemical modification, it can be converted into compounds with unique aromas. Or compounded with other fragrance ingredients to prepare unique fragrance products for use in perfumes, cosmetics, food additives and other industries to add a pleasant aroma to the products.

What are the physical properties of 3-iodobenzaldehyde?

3-Iodobenzaldehyde, its physical state is light yellow to yellow crystalline powder at room temperature. The melting point is between 46-49 ° C. This melting point characteristic makes 3-iodobenzaldehyde change from solid to liquid when approaching this temperature range. The boiling point is about 265 ° C. When the temperature rises to this point, the substance changes from liquid to gaseous.
In terms of solubility, it is slightly soluble in water, but soluble in organic solvents such as ethanol and ether. The poor solubility in water is due to the fact that water is a highly polar solvent, while the polarity of 3-iodobenzaldehyde molecules is relatively weak. According to the principle of "similar miscibility", the two are difficult to miscible. It has good solubility in organic solvents such as ethanol and ether because the polarity of these organic solvents is similar to that of 3-iodobenzaldehyde.
3-iodobenzaldehyde has a certain degree of volatility and will slowly evaporate into the air in an open environment. Its density is greater than that of water. If it is accidentally mixed with water, it will sink to the bottom of the water. In terms of chemical stability, 3-iodobenzaldehyde is relatively stable under conventional conditions, but when it encounters strong oxidants, strong acids, strong bases and other substances, it is prone to chemical reactions, resulting in changes in its structure and properties. In addition, it is more sensitive to light. Long-term light exposure may trigger photochemical reactions, affecting its quality and performance.

What is the market price of 3-iodobenzaldehyde?

3-Iodobenzaldehyde is also an organic compound. The price of its market is not fixed, and it varies for various reasons.
First, the land and quality of the product have a great impact on the price. If the origin is close, and the quality is high, the price may be slightly cheaper. However, the origin is far away, and it needs to be far away, the cost will increase, and the price will increase. And those with high quality will cost time, labor and materials, and the price will also be high.
Second, the supply and demand of the market is also the key. If there are many people seeking, but the supply is limited, for profit, the seller may raise the price. On the contrary, if the supply exceeds the demand, the seller will sell the goods, or reduce the price to lure the buyer.
Furthermore, the cost of manufacturing this product is also related to the price. The price of raw materials rises, and the cost of labor and energy consumption is added. The cost of manufacturing is high, and its price in the market is high.
In addition, the competition of the market also affects its price. There are many sellers, who want to win customers, or reduce prices to compete. The sole seller, or with its monopoly, sets a high price.
At present, the market situation is changing rapidly, and the price is difficult to determine. To know the exact price of 3-iodobenzaldehyde, when consulting the supplier of chemical raw materials, or checking the special market situation report, you can get a near-real price.