What are the main uses of 3-iodoindazole?
There are three main uses for the 3-bumps of nitrate. First, it is used for the conquest, which can help the journey. Ancient things, equipment, and the might of fire can break the city. If you siege the city, if you use the firearms made of nitrate, you can collapse the city.
Second, it is beneficial for the construction of the project. Such as mountains and roads, when encountering rocks and obstacles, manpower will use it. With nitrate blasting, it can be reduced to rocks and broken pieces, so that the project can be used for profit. Repairing rivers and excavating roads can achieve miraculous results, saving people's strength and speeding up the speed of the project.
Third, it can also be used in the art of art. Every time there is a good time, the flowers are released, the flowers are burned, and the brilliance is always beautiful. It can increase the joy of the day and help the people. Flowers are in the sky, and they are colorful, or they dance like flowers, or they are like stars falling, which attracts people's calls and adds to the atmosphere of peace and joy.
In this way, 3-bumps are of great use in matters, engineering, and engineering, and it is also indispensable to the world.
What are the synthesis methods of 3-iodoindazole?
3-Carbonyl butyric acid, also known as acetoacetic acid, has many synthesis methods, which are described in detail below.
First, Claisen Condensation Method: Using ethyl acetate as the starting material, under the action of strong bases such as sodium alcohol, two molecules of ethyl acetate undergo a condensation reaction. The α-hydrogen of one molecule of ethyl acetate is taken away by the base to form a carbon negative ion. This carbon negative ion performs nucleophilic addition to the carbonyl of another molecule of ethyl acetate, and then loses the ethoxy negative ion to form ethyl acetate. The reaction formula is as follows:
\ (2CH_ {3} COOC_ {2} H_ {5}\ xrightarrow [] {C_ {2} H_ {5} ONa} CH_ {3} COCH_ {2} COOC_ {2} H_ {5} + C_ {2} H_ {5} OH\). Ethyl acetoacetate is hydrolyzed and acidified to obtain 3-carbonyl butyric acid.
Second, diethyl malonate Synthesis: Diethyl malonate reacts with halogenated acetate under the action of a strong base to introduce a carboxyl group substituent. After hydrolysis and decarboxylation, the target product can be obtained. For example, diethyl malonate reacts with ethyl bromoacetate under the action of sodium ethyl alcohol to generate the corresponding substituted diethyl malonate, which can be hydrolyzed, acidified, and decarboxylated by heating to obtain 3-carbonyl butyric acid. The reaction steps are as follows:
\ (CH_ {2} (COOC_ {2} H_ {5}) COOC_ {2} + BrCH_ {2} COOC_ {2} H_ {5}\ xrightarrow [] {C_ {2} H_ {5} ONa} C_ {2} H_ {5} OOCCH (CH_ {2} COOC_ {2} H_ {5}) H_ {2}\);
\ (C_ {2} H_ {5} OOCCH (CH_ {2} COOC_ {2} H_ {5}) H_ {2}\ xrightarrow [] {H_ {2} O/H ^ {+}} HOOCCH (CH_ {2} COOH) CH_ {2}\);
\ (HOOCCH (CH_ { 2} COOH) _ {2}\ xrightarrow [] {\ Delta} CH_ {3} COCH_ {2} COOH + CO_ {2}\ uparrow\).
Third, synthesized from acetylacetone: acetylacetone and formaldehyde undergo hydroxyaldehyde condensation reaction under basic conditions to generate corresponding β-hydroxy compounds, and then 3-carbonylbutyric acid can be prepared by oxidation, hydrolysis and other steps.
Fourth, acetyl chloride and malonic acid are used as raw materials: acetyl chloride reacts with malonic acid in the presence of an appropriate catalyst to form an intermediate product, which can be obtained by subsequent treatment. In this process, the reaction conditions need to be precisely controlled to ensure the smooth progress of the reaction.
What are the physical and chemical properties of 3-iodoindazole?
The physicochemical properties of 3-nifurane are as follows:
This material is often in the form of a chromatic crystal powder. Its melting properties are particularly high, between 190 and 192 degrees Celsius. In terms of solubility, 3-nifurane dissolves in water, but has a certain solubility in solvents such as dimethylformamide and dimethyl.
In terms of its chemical properties, the molecule contains nitro groups, so it has a certain degree of oxidation. This property makes 3-nifurane in some chemical reactions, which can be filled with oxidation. In addition, its furan also makes it exhibit specific chemical activity. Under suitable conditions, it can generate reactions such as chemical substitution, and other functional groups are introduced into it.
The characterization of 3-nifuran depends on the environment. In the environment of constant dryness and darkness, the phase stability can still be maintained. However, in the presence of high temperature, acid, or oxidation conditions, its degradation is easily broken, leading to decomposition and reversal. The decomposition process or release of nitrogen oxides and other substances.
In terms of acidity, due to the molecular properties of 3-nifuran, 3-nifuran is neutral, neither acidic nor acidic. This property determines its inverse orientation in the acid medium. Under normal acid conditions, it does not neutralize and reverse the reaction of acids or raw acids, but is mostly due to its oxidation and furan activity.
What is the price of 3-iodoindazole in the market?
In today's market, the price of San Baijiu varies from time to time, and it varies from place to place. The change in its price is related to various reasons, so listen to me in detail.
The first one is because of the materials. Three Baijiu is made of rice, wheat, and water. The quality of rice, the new age of wheat, and the sweetness of water all have a great impact on the taste and quality of wine. If you use refined rice, new wheat, and clear springs, the wine you make will be good, and the price will be higher; on the contrary, if the materials are ordinary, the wine quality will be slightly inferior and the price will be slightly lower.
Both are also important brewing methods. Those who are good at brewing, according to the ancient law, are punctual, and control the heat, their wine is mellow and rich, and everyone loves it, so the price will be high. If the brewing method is not proper, the flavor of the wine will be lost, and the price will be difficult to be high.
Furthermore, the origin is related to fame. If in the hometown of famous wine, the craftsmanship has been passed down for a long time and the reputation is far spread, the price of the wine is often the highest. There are also famous shops brewing, which have a well-known reputation, and everyone believes it, and the price can be viewed.
In addition, the supply and demand of the city determine the price. On festive festivals and celebrations, everyone wants to buy wine, and if they need to supply more and less, the price will be raised; on weekdays, if they need to supply
Generally speaking, Baijiu is the third most common in the market. For ordinary people, the price per bucket or tens of dollars; for those who are fine brewed and famous, the price per bucket can reach hundreds of dollars, or even more. However, the market is volatile, and the price is not fixed. Buyers should check according to the time and consider according to the place, so that they can get wine with affordable price.
What are the storage conditions for 3-iodoindazole?
3- Those who hide sugar have their own way of hiding it. In the past, the method of hiding things in the "Heavenly Works" was used, and there was also a way to investigate the collection of sugar.
Where sugar is hidden, it is the first priority. It is appropriate to be in a place where things are dry, and to avoid it. Sugar is easy to absorb moisture, causing it to melt and shape, and even mildew. Therefore, the room where it is hidden must be well connected, so that the air can flow and the water vapor can gather.
For the second time, the degree is also important. It should not be exposed to the hot sun. High temperatures can make sugar dissolve and burn quickly. During the summer, you need to pay special attention. If you can get a cool place, so that sugar can be stored in a suitable place, you can hide it for a long time without burning.
Furthermore, the package also contains sugar. Wrapped in a vase, it can be separated from the outside world. It is better if it is held in a dense vessel. Such as pottery pots and porcelain vases, sealed, can be empty and empty, sugar can last for a long time.
And when it is hidden in sugar, it is also necessary to prevent rats. Rats like to eat sweetness, and rats are also good. Hidden in a vase, there should be no gaps and caves to prevent rats from entering. Or in a vase, it is necessary to pay attention to the separation of sugar and sugar, so as not to dye each other.
If this method of hiding sugar is followed, the sugar can be hidden for a long time, and the taste will not be changed, so that people can enjoy its sweet taste without losing its original taste.
