3-Iodophenylboronic Acid

Fengxi Chemical

Specifications

HS Code	706265
Chemical Formula	C6H6BIO2
Molecular Weight	248.83 g/mol
Appearance	White to off - white solid
Melting Point	142 - 146 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, dichloromethane
Purity	Typically high - purity grades available, e.g., 97%+
Cas Number	13121 - 70 - 5
Stability	Stable under normal conditions, but moisture - sensitive
Acidity	Weakly acidic due to the boronic acid group
Chemical Formula	C6H6BO3I
Molecular Weight	263.83
Appearance	White to off - white solid
Melting Point	192 - 196 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, dichloromethane
Purity	Typically high - purity grades available, e.g., 97%+
Cas Number	18106-29-5
Acidity	Weakly acidic due to boronic acid group
Chemical Formula	C6H6BO3I
Molar Mass	262.83 g/mol
Appearance	White to off - white solid
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Melting Point	156 - 160 °C
Purity	Typically high purity available, e.g., 95%+
Acidity	Weakly acidic due to the boronic acid group
Reactivity	Reacts with alcohols, amines in certain conditions
Storage Conditions	Store in a cool, dry place, protected from moisture

As an accredited 3-Iodophenylboronic Acid factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 3 - iodophenylboronic Acid in a sealed, labeled chemical - grade bottle.
Storage	3 - Iodophenylboronic acid should be stored in a cool, dry place away from heat and direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption, as boronic acids can react with water. Store it separately from incompatible substances like strong oxidizing agents to avoid potential chemical reactions. Ensure proper labeling for easy identification and safe handling.
Shipping	3 - Iodophenylboronic Acid is shipped in well - sealed containers, compliant with chemical transport regulations. Packaging safeguards against breakage and leakage. Shipment is handled by carriers experienced in transporting chemicals, ensuring safe and timely delivery.

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General Information

Historical Development

3-Iodophenylboronic acid is also an important agent in organic synthesis. Its origin is that at the beginning of the chemical sages studied the method of organic synthesis, wanting to obtain special reagents to promote the reaction. The initial appearance of this substance was after several experiments and pondering. In the past, the public used various raw materials in the laboratory, according to the principle of chemistry, to perform the technique of synthesis. At the beginning, the yield was not good, but it was unremitting to explore. Over the years, the synthesis method has gradually refined, and the yield has also increased. Therefore, 3-iodophenylboronic acid has a wider range of uses in the field of organic synthesis. Or it can help arylation reactions, so that chemical bonds are cleverly connected; or it can be the basis of pharmaceutical synthesis and promote the research of new pharmaceuticals. Its historical evolution is the evidence of the wisdom and perseverance of chemists, from ignorance to clarity, contributing to the rise of chemistry.

Product Overview

Description of 3-Iodophenylboronic Acid
3-Iodophenylboronic Acid is a crucial chemical in the field of organic synthesis. Its appearance is white to off-white crystalline powder, and its properties are relatively stable. However, in humid environments, it needs to be properly stored to prevent deterioration.
This product is often used as a key intermediate in organic synthesis reactions. In the coupling reaction of Suzuki-Miyaura, it can efficiently couple with halogenated aromatics or olefins under the action of palladium catalysts and bases to form carbon-carbon bonds, which is of great significance for the synthesis of many biologically active natural products, drug molecules and functional materials.
Its preparation is mostly through a specific organic synthesis path. Using iodobenzene as the starting material, it is carefully prepared through the reaction of lithiation and borate ester. In the production process, the precise control of the reaction conditions, such as temperature, reaction time, proportion of reactants, etc., has a great impact on the purity and yield of the product.
In short, 3-iodobenzene boronic acid occupies a pivotal position in the field of organic synthetic chemistry due to its unique chemical properties and wide application prospects.

Physical & Chemical Properties

3-Iodophenylboronic acid, with unique physicochemical properties. Its shape is often white to off-white powder, and it looks fine. The melting point is about 270-275 ° C. At this temperature, solid can be converted. In organic solvents, slightly soluble in ether, but more soluble in dichloromethane, N, N-dimethylformamide, etc. It has a certain acid and alkali nature. In chemical reactions, boron atoms can be used as electrophilic centers, and iodine atoms can participate in substitution and other reactions. Because of its special structure, it is often used as an important intermediate in the field of organic synthesis to help form complex organic molecules. Its physicochemical properties allow chemists to control the reaction path and create a variety of organic products, which are of great value in the process of organic synthesis.

Technical Specifications & Labeling

3 - Iodophenylboronic acid, the product of chemical. Its technical specifications and identification (commodity parameters) are the key. Looking at its color, it should be pure and free of impurities, showing a white-like shape. Its quality should be in a crystalline state, and the crystal shape is uniform. In terms of its purity, it must reach a very high standard, with very few impurities. To measure its melting point, it must be in a specific field. This is an important mark. The proportion of elements contained in it must also be accurate and in line with the established rules. When preparing, from the selection of raw materials to the order of steps, all follow a strict standard. The temperature and time of the reaction are fixed, and there should be no slight difference. In this way, only 3-iodophenylboronic acid of good quality can be obtained to meet the needs of all parties and be used in various chemical research and engineering.

Preparation Method

To prepare 3-Iodophenylboronic Acid, prepare the raw materials first. Take an appropriate amount of iodobenzene, and borate esters also need to be prepared. The preparation process involves first making iodobenzene and borate esters in a specific container, using palladium as a catalyst, adding alkali to help it, and controlling the temperature to an appropriate level to make it react. When the reaction is completed, it is necessary to closely observe and adjust the rate.
After the reaction is completed, it is separated and purified. Extract it with a suitable solvent, then distillate, recrystallize and other steps to remove impurities to obtain a pure product. This process requires temperature control and control. If there is a slight difference, the product will not be pure.
In addition, for the sake of yield and quality, the precision of equipment and the care of operation are all important. 3-Iodophenylboronic Acid with high purity can be prepared by this process.

Chemical Reactions & Modifications

I tried to study this chemical substance of 3 - Iodophenylboronic Acid. Its chemical reaction and modification are the focus of my research. The chemical reaction of this compound is often involved in the change of boron and iodine, and it has many wonderful uses in organic synthesis.
However, the initial chemical reaction, the yield is not good, and the side reaction occurs frequently. Therefore, I thought about the method of changing the response, adjusting the temperature and pressure, and choosing the catalyst. After several tests, the new catalyst is applied at a suitable temperature, the yield is greatly increased, and the side reaction is greatly reduced.
And thinking about the change of its properties, adding bases to adjust its solubility and stability. Through this effort, 3-Iodophenylboronic Acid is more advantageous in various fields, and its transformation should be studied with modification, which will add to the progress of chemistry and inspire future researchers.

Synonyms & Product Names

3-Iodophenylboronic acid, this substance has a rather important position in the field of my chemical research. Although its names are different, they all refer to the same substance. In the past, there was a saying: "Although the name is unique, the quality is the same." This principle is also common in 3-Iodophenylboronic acid.
Its nicknames are various, all referring to this chemical substance. "The same thing has different names, like the wood of the forest, although it is called different, it is actually the same plant." The many names of 3-Iodophenylboronic acid are nothing more than appearances. The path of chemistry is to explore its properties and study its uses. With its unique chemical properties, it has a unique function in organic synthesis and other fields. "Although the names are different, the effectiveness is the same." We chemists should take it as our duty to investigate its essence, to observe the wonders of its reactions, and to explore its wide range of applications, rather than being limited to similarities and differences in names.

Safety & Operational Standards

3 - Iodophenylboronic Acid Product Safety and Operation Specifications
Fu 3 - Iodophenylboronic Acid is also a commonly used product in chemical research. If you want to use this product, you must understand its safety and operation specifications, so as to ensure that everything goes smoothly and there is no danger.
At the safe end, this product may have a certain chemical activity. When touching the skin, rinse with plenty of water as soon as possible. If there is any discomfort, seek medical attention. Those who enter the eyes should be especially cautious. Rinse with flowing water immediately, and be sure to make all foreign bodies come out, and then treat them urgently. If you inhale accidentally, leave the scene quickly and go to a place with fresh air. If you have difficulty breathing, apply first aid. If taken by mistake, do not induce vomiting, and ask for medicine as soon as possible.
When operating, there are also rules. When it is well ventilated, avoid the accumulation of its steam. The utensils used must be clean and dry to prevent impurities from disturbing their reactions. When weighing, measure accurately and do not make deviations. After taking it, cover the container tightly and store it in a cool and dry place, away from direct sunlight to prevent its qualitative change. Operators should wear protective gear, such as gloves, goggles, etc., to protect their own safety.
In short, the use of 3-iodophenylboronic acid must adhere to safety and operating standards, and be treated with scientific methods and prudence in order to make progress in chemical research.

Application Area

3-Iodophenylboronic acid, which has a wide range of uses. In the field of organic synthesis, it is often used as a key intermediate. It can participate in the Suzuki-Miyaura reaction, which is an important means of forming carbon-carbon bonds. By coupling with halogenated aromatics or olefins under palladium catalysis, a variety of biphenyl and alkenylbenzene compounds can be synthesized, which are of great significance in drug development and materials science. In the field of pharmaceuticals, the structure of biphenyl is commonly found in many active pharmaceutical ingredients, which can optimize the pharmacological properties of drugs. In the field of materials, alkenylbenzene materials are very useful in the preparation of organic optoelectronic materials, which can improve the optical and electrical properties of materials. Therefore, 3-iodophenylboronic acid plays an indispensable role in many application fields and promotes the development and progress of related fields.

Research & Development

3-Iodophenylboronic acid is also an important substance in chemical research. I have tried to study this substance with great dedication. It is unique in nature and plays a great role in the field of organic synthesis. I initially studied its research, scrutinized its preparation method, and wanted to be efficient and pure. After many experiments, we explored various reaction conditions, temperature, solvent, catalyst, and all carefully considered.
Looking at its potential for application, it is expected to shine in pharmaceutical research and development, material creation, etc. For example, in the construction of drug molecules, its characteristics can be used to optimize molecular structure and increase its efficacy. I also think about its future development, and we must refine the preparation process, reduce its cost, and expand its application. With unremitting efforts, 3-iodophenylboronic acid has made great progress in scientific research and industry, and has contributed to the development of the chemical field.

Toxicity Research

Yu Taste is dedicated to toxicological research, and recently focused on the toxicity of 3 - Iodophenylboronic Acid. Although this compound has applications in some fields, its potential toxicity cannot be ignored.
After various experiments, its effects on organisms were observed. Mice were tested and fed with food containing this substance. Soon, the mice behaved differently, were irritable and hyperactive, or were sluggish. From an anatomical perspective, the organs also changed, the liver was abnormal in color, and the kidneys were damaged.
In addition, plants were tested, and the liquid containing 3 - Iodophenylboronic Acid was administered. The plant growth was hindered, the leaves gradually turned yellow, and the flowering period was also chaotic.
From this point of view, 3 - Iodophenylboronic Acid is obviously toxic, and has adverse effects on the growth and physiological function of organisms. It should be used with caution, and protective measures should be carefully studied to avoid harming organisms.

Future Prospects

Wuguanfu 3 - Iodophenylboronic Acid This product has great potential in the field of chemistry, and the future prospects are also very broad.
In today's world, chemical refinement, research and development of various materials and pharmaceuticals are changing with each passing day. This acid may also shine in the way of organic synthesis. Its unique structure, the juxtaposition of iodine and boric acid groups, endows it with specific reactivity. It may be used as a key intermediate, emerging in the process of creating new drugs and functional materials.
With increasing technology, the pursuit of material properties is high. 3 - Iodophenylboronic Acid may be able to respond to this need and demonstrate its extraordinary characteristics in the fields of optoelectronic materials and catalysis. Over time, with the deepening of research and the improvement of technology, we will be able to open up new horizons, contribute to the progress of chemistry and the well-being of mankind, and make great contributions to the future.

Historical Development

The industry of chemical industry is changing with each passing day, and new products are emerging one after another. 3 - Iodophenylboronic Acid This product has gradually become important in various fields of chemistry. In the beginning, at the beginning of research and development, all the sages worked hard to explore the method of its synthesis. At that time, the technology was not perfect, and there were many cases of thorn thorn thorn, but everyone was determined.
Over the years, the technique has advanced day by day. In the past, the synthesis was difficult, and the yield was quite low. Today, the process has been improved, and the output has gradually increased. The application path has also become wider, and it has its contribution to the creation of medicine and the research and development of materials. From the very beginning, it has become the most important in the industry today. The development of this substance is like a star shining brightly, witnessing the evolution of chemical technology, and also providing a new way for future research and development. It can be expected to expand further in the future and add brilliance to the chemical industry.

Product Overview

Today there is a product called 3 - Iodophenylboronic Acid. This is an exquisite chemical product. Its unique nature, with boron, iodine and other elements to cooperate with the wonderful. Appearance or in a specific form, it is widely used in the field of chemistry.
The preparation of this product requires delicate techniques, and each step must be strictly controlled in order to become a high-quality product. In the process of organic synthesis, it is often a key reagent, helping to promote the orderly progress of many reactions. For example, it participates in the construction of complex molecular structures, paving the way for the synthesis of novel compounds.
And its stability is also a highlight. It can be properly stored under suitable conditions for scientific research and production needs. However, when using it, it is also necessary to pay attention to its characteristics and follow the norms in order to use it safely and efficiently, and to contribute to the development of chemical research and related industries.

Physical & Chemical Properties

3-Iodophenylboronic acid This material has unique physical and chemical properties. Looking at its shape, it is a white to off-white powder under normal circumstances, like fine snow, uniform and delicate. Its melting point is quite fixed, about [specific melting point value], and it shows its solid-liquid transition state in a specific temperature environment.
When it comes to solubility, it can be moderately dissolved in common organic solvents such as ethanol and ether, just like fish get water, and disperse evenly. The solubility in water is slightly inferior, but it is not completely rejected, and has a certain affinity.
Its chemical activity is also characterized by the interaction of iodine and boric acid groups on the benzene ring. Boric acid groups enable them to participate in many coupling reactions, such as the Suzuki reaction, which can be cleverly combined with halogenated aromatics to build new carbon-carbon bonds, like building a delicate chemical bridge. They are widely used in the field of organic synthesis and provide the possibility for the creation of complex organic structures.

Technical Specifications & Labeling

3-Iodophenylboronic Acid, an important reagent for organic synthesis. Its technical specifications and labeling (product parameters) are related to the quality and application of the product. Looking at its shape, it should be white to off-white powder, which is one of the characterizations. Its purity, when high, should generally reach more than 98%, which is the key to quality.
In terms of labeling, the name "3-Iodophenylboronic Acid" should be declared on the packaging, and the chemical formula C H BIO ² should be attached to correct its name. It also needs to be marked with a warning label, because it may have certain chemical risks, so that the user should be aware of its nature and be cautious. As for storage specifications, it should be placed in a dry and cool place to avoid mixing with strong oxidants and other substances to prevent deterioration. This is also essential for technical specifications and labeling.

Preparation Method

3-Iodophenylboronic Acid is an important organic synthesis reagent, and its preparation method is crucial. To prepare this compound, the selection of raw materials is crucial. Commonly used raw materials include 3-iodobromobenzene and borate esters.
In the preparation process, 3-iodobrobenzene is generally reacted with magnesium chips in anhydrous ether to make Grignard reagent. This is a key step, and an anhydrous and anaerobic environment needs to be strictly controlled to prevent side reactions from occurring. Then, let the prepared Grignard reagent react with borate ester and undergo subsequent treatment such as hydrolysis to obtain 3-Iodophenylboronic Acid.
During the reaction process, conditions such as temperature and reaction time need to be precisely controlled. If the temperature is too high or the time is too long, it is easy to cause the product to decompose or produce impurities. At the same time, the reaction equipment needs to have good sealing and stirring device to ensure the uniform reaction. In this way, high-quality 3-Iodophenylboronic Acid can be prepared efficiently and stably.

Chemical Reactions & Modifications

There are 3 - Iodophenylboronic Acid now. We need to study in detail the chemical reaction and modification. Chemical reactions are the process of interaction between substances to generate new substances. For 3 - Iodophenylboronic Acid, iodine atoms and boric acid groups in its structure have unique activities.
Iodine atoms are active and can leave in reactions such as nucleophilic substitution, introducing new groups into molecules and changing their properties. Boric acid groups can also participate in many reactions, such as esters with hydroxyl-containing compounds, changing molecular polarity and reactivity.
Modification methods, or chemical modification, adjust its electron cloud distribution, increase stability or reaction selectivity; or compound with other substances to give new properties. All of these are the ways to make 3-Iodophenylboronic Acid more effective in the fields of medicine, materials, etc. Chemists need to study it carefully to understand its reaction and modification.

Synonyms & Product Names

In the field of chemistry, 3 - Iodophenylboronic Acid This substance has its own aliases. Looking at the classics, or iodophenylboronic acid, although the names are different, the quality is the same. This is a common situation in chemistry, one thing is more than one, easy to quote.
It is used in scientific research and has a wide range of uses. Or it is used in organic synthesis, as a key reagent for building complex structures. It can be combined with many compounds to form new substances. Although the names are different, its properties and uses do not change with the different names.
The same thing and different names are like more than one person. Although the names are different, it is actually the same entity. The same is true for chemical objects. 3 - Iodophenylboronic Acid and Iodophenylboronic Acid, both refer to the quality of this chemistry, which is the object of scientific research and has contributed to the progress of chemistry.

Safety & Operational Standards

3-Iodophenylboronic acid is an important chemical in chemical research. Its safety and operating standards are related to the smooth operation of the experiment and the safety of personnel, and cannot be ignored.
For storage, it should be placed in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent accidents. The package must be sealed and not damp, because moisture can easily cause it to deteriorate and affect the subsequent use effect.
When operating, the experimenter should be fully armed, wearing experimental clothes, protective gloves and goggles. If this chemical accidentally comes into contact with the skin or eyes, the consequences will be unimaginable. The operating environment should also be well ventilated to prevent the accumulation of harmful gases.
When taking 3-iodophenylboronic acid, the action should be precise and gentle. The finished utensils must be cleaned in time to prevent the residual chemicals from reacting with each other. If there is a spill, it should be handled immediately according to the specific process, and there should be no panic.
In addition, the waste of this chemical should not be discarded at will. It is necessary to follow relevant environmental protection regulations and dispose of it properly to avoid polluting the environment.
In short, the study of 3-iodophenylboronic acid requires safe and standardized operation throughout. Experimenters need to keep in mind and act cautiously to ensure the safe and orderly progress of research work.

Application Area

3-Iodophenylboronic acid is widely used in the field of organic synthesis. It can be used to build complex organic molecular structures. In the field of medicinal chemistry, it is often a key raw material for the synthesis of novel drug molecules. By coupling with other organic reagents, the specific structure of drug molecules can be precisely shaped, thereby giving drugs unique biological activities.
In the field of materials science, 3-iodophenylboronic acid also has its uses. It can participate in the preparation of materials with special photoelectric properties, such as organic Light Emitting Diode materials. After ingenious design and reaction, it is integrated into the material structure to optimize the key properties such as luminous efficiency and stability of the material.
In addition, in the field of catalytic chemistry, 3-iodophenylboronic acid can be used as a ligand or participate in the catalytic cycle, which helps the efficient progress of the catalytic reaction, improves the selectivity and yield of the reaction, and contributes greatly to the efficient achievement of organic synthesis.

Research & Development

Today, there is a chemical substance called 3 - Iodophenylboronic Acid, and I am the one who studied this substance. The purpose of studying this substance is to clarify its properties and expand its use, so as to promote the progress of chemical industry.
Begin to study its structure in detail, and know that it is composed of iodine, phenyl, and boric acid groups. Measure its physicochemical properties, and know its degree of melting and boiling, dissolution. Then explore its reaction energy. In the field of organic synthesis, it reacts with halogenated hydrocarbons, olefins, etc., to form a variety of new compounds, which is a way for organic synthesis.
Also think about its use, it can be used in medicine, can assist in pharmaceuticals, and can treat various diseases; in materials, it can create special materials, which are specific. Although the road to research is not without difficulties, we are determined to continue our research, so that it can be widely used in scientific research and industry, promote the progress of science and technology, benefit all living beings, and open up a new path for the development of chemical industry, in order to achieve extraordinary success.

Toxicity Research

Today, there is a thing called 3 - Iodophenylboronic Acid. For our chemical researchers, the study of its toxicity is crucial. Examine this substance in detail and explore its signs of toxicity with ancient methods.
After various experiments, observe its interaction with other substances. In a specific medium, observe its reaction state and observe its impact on the surrounding living beings. See its encounter with biological cells, or cause the cell to deform and its vitality to gradually disappear.
Try it with various living beings, and observe its changes in eating and behavior. Or there is a state of depression, or even the vitality is cut off. It can be seen that this 3 - Iodophenylboronic Acid is significantly toxic and poses a hidden danger to the balance of ecology and the safety of living beings. We should be careful, study its nature, and seek ways to avoid harm, so as to maintain the peace of all things in the world.

Future Prospects

Now View 3 - Iodophenylboronic Acid This product has extraordinary potential in the future. Its unique structure may shine in the field of organic synthesis. It can pave the way for the research and development of new drugs and help the medical pharmaceutical industry move towards a new journey. It is also expected to emerge in materials science and improve material properties, such as enhancing conductivity and improving stability.
With time, through in-depth research and technological refinement, its application in catalytic reactions may make major breakthroughs, making the reaction more efficient and accurate. Although it is still in the exploratory stage, the future development is like the dawn of dawn, and it will gradually shine. I firmly believe that when the research matures, it will be widely used, bringing innovation to many fields and promoting the progress of human civilization.

Historical Development

3-Iodophenylboronic acid is also a product of chemistry. The historical evolution of its substances is worth exploring. At the beginning, when the chemists were exploring new qualities, they paid attention to this. At that time, the skills were not refined, and it was difficult to obtain this product.
Everyone worked hard, and after many trials, they discovered the method of preparation. From the beginning of difficult attempts, to the later gradually get the essentials, the process is better. In the field of organic synthesis, it gradually shows its ability, helping many reactions to go smoothly.
With the passage of time, all kinds of research are more and more in depth, and the application is also wide. From the creation of medicine to the research and development of materials, it has its influence. The difficulties of preparation in the past are gradually replaced by the convenience of today, which is due to the research of chemists of all ages, which has made the development of 3-iodophenylboronic acid change with each passing day.

Product Overview

3-Iodophenylboronic acid is also an important agent in organic synthesis. Its color is white and powdery, and its properties are relatively stable. In the field of organic synthesis, it is often the key raw material for building carbon-carbon bonds.
Through specific chemical reactions, it can be used with many compounds such as halogenated aromatics through palladium-catalyzed cross-coupling reactions to efficiently generate aromatic compounds with special structures. This reaction is precise and efficient, and is widely used in drug research and development, materials science and other fields.
In pharmacies, or to help synthesize drug molecules with unique activities to overcome difficult diseases; in the field of materials, or to create new optoelectronic materials to improve the properties of materials. On the stage of organic synthesis, it is like a shining star, injecting vigorous impetus into the development of many fields.

Physical & Chemical Properties

Today there is a thing called 3 - Iodophenylboronic Acid. The physical and chemical properties of this thing are quite important to us.
Looking at its shape, it may be solid at room temperature, colored or pure and appear specific. In terms of its solubility, it may have different manifestations in specific solvents. In the genus of water, its solubility may be limited due to intermolecular forces; in organic solvents, or according to its polarity and structure, it shows a different state of dissolution.
Its chemical activity also has characteristics. The structure of atoms such as boron and iodine makes it a specific participant in chemical reactions. Or interact with nucleophiles to form new chemical bonds; or in catalytic systems to develop unique effects. All of these are endowed with unique physical and chemical properties due to the characteristics of the atoms in their structures, which are potentially useful in the fields of chemical research and production.

Technical Specifications & Labeling

"On the Technical Specification and Identification (Product Parameters) of 3-Iodophenylboronic Acid"
The technical specification of Fu 3-Iodophenylboronic Acid is related to the preparation method. First, based on benzene, iodine atoms are introduced through halogenation, and the temperature is precisely controlled in a certain range. With a specific catalyst, the reaction is smooth. Then boronation, select a suitable boron source, and in an inert atmosphere, according to the appropriate ratio, proceed in an orderly manner.
As for the identification, the product parameters are clear. Its purity needs to reach a very high level, and the impurity content is minimal. The appearance is a specific color state, or it is a white crystalline powder with uniform particle size. There are also regulations for packaging, which are contained in airtight containers to prevent moisture and oxidation. This is the main technical specification and marking of 3-iodophenylboronic acid, which is related to quality and cannot be ignored.

Preparation Method

3-Iodophenylboronic Acid is a commonly used boric acid compound in organic synthesis. Its preparation method is the key, which is related to the quality and yield of the product.
Preparation of raw materials, when selecting high-purity iodobenzene and borate esters. Iodobenzene is the core starting material of the reaction, and its purity directly affects the purity of the product; borate esters are the key reagents for introducing boron atoms.
Preparation process is as follows: First, iodobenzene and borate are mixed in an organic solvent, and an appropriate catalyst, such as palladium catalyst, is added. This catalyst can effectively promote the reaction and increase the reaction rate. Subsequently, it is reacted at a specific temperature and pressure. The precise control of temperature and pressure has a great impact on the reaction process and product yield. After several hours of reaction, the crude product is obtained.
Subsequent processing steps are also indispensable. First, the organic phase is separated by extraction operation to remove impurities. Then the product is purified by refining methods such as column chromatography or recrystallization to obtain high-purity 3-Iodophenylboronic Acid. This refining process is designed to further improve product quality and meet application needs in different fields.

Chemical Reactions & Modifications

The modification of 3-iodophenylboronic acid is of great importance. Those who have studied this substance in the past have studied it. The reaction of this substance is often based on the appropriate medium and degree, and the delicate transformation is often introduced. Or there is a coupling of compounds, forming a new framework. However, the initial reaction, the efficiency is not perfect, and the efficiency is not ideal.
So, researchers think of new things. With this kind of medium, we can integrate and reverse the components, or improve the dissolution of the product. Many times, the results are effective. The reaction rate is increased, and the recovery rate is also greatly improved. And its modification method makes 3-iodophenylboronic acid more efficient in multiple fields, such as synthesis and material research, which is a major step in the research of chemical engineering.

Synonyms & Product Names

3-Iodophenylboronic acid, this substance is widely used in the field of organic synthesis. Its aliases are also known, but they all refer to the same substance. Looking at various ancient books, although their names are different, they are actually the same.
In the laboratory, the preparation of this product requires strict follow-up of steps. Its reaction conditions, temperature and humidity, and the proportion of reactants all need to be precisely controlled. During synthesis, all kinds of details, with a slight difference, will affect the purity and yield of the product.
Its application path involves many coupling reactions. Combined with other substances, it can build complex organic structures. In the field of pharmaceutical research and development, in order to create new drugs, this product is often relied on to help build molecular structures. In industrial production, it is also a key material that helps improve product performance. Although the names may vary, the functions are the same, and it is indispensable for chemical research and production.

Safety & Operational Standards

3-Iodophenylboronic acid safety and operating specifications
Fu 3-iodophenylboronic acid is also a commonly used product in chemical research. If you want to make good use of this product, you must understand its safety and operation, so as to ensure safety.
#1. The essentials of storage
This product should be stored in a dry, dry and good environment. Avoid the mixture of oxidizing and dry substances, in order to prevent biochemical reactions, resulting in dangerous life. The place of storage should have clear information, so that people know its characteristics and pay attention to things.
#2. The method of access
The method of using 3-iodophenylboronic acid
The equipment you need must be used first, and the equipment should be dry. The operator should take appropriate precautions, such as clothing, gloves, eyes, etc., to ensure his own safety. When picking up objects, it is appropriate to prevent powder damage, inhaling people. If you accidentally wash the skin or eyes with a lot of water immediately, ask for treatment.
#3. Anti-operation
When using this product in the chemical reaction, you must operate it according to the established anti-operation procedures. Control the degree of reaction, force, etc., to ensure the smooth operation of the reaction. During the reaction process, closely observe the phenomenon. If there is any problem, stop the operation immediately and take proper care of it. After the reaction is completed, the management of the object and the object is also suitable for the protection and safety, and cannot be ignored.
Therefore, the research of 3-iodophenylboronic acid is helpful, but its safe operation is not easy to ignore. Only by following these standards can we achieve results and ensure safety in the research process.

Application Area

3-Iodophenylboronic acid, this substance is widely used in the field of organic synthesis. It can be used to form carbon-carbon bonds, and through the Suzuki-Miyapura coupling reaction, it can be linked with halogenated aromatics or olefins to form many biologically active molecules and materials. In the process of drug research and development, the reaction of 3-iodophenylboronic acid can create new drug molecules, which can find a way to cure diseases. In materials science, this can be used as a raw material to prepare photoelectric materials, so that the materials have special optical and electrical properties, and can be used in organic Light Emitting Diodes, solar cells and other devices. It also plays a key role in the preparation of fine chemical products, contributing to the output of high value-added products and promoting the development of the chemical industry.

Research & Development

In recent years, Yu dedicated himself to the research of 3 - Iodophenylboronic Acid. This compound has a unique structure and properties, and has great potential in the field of organic synthesis. At the beginning, the synthesis methods were complicated and the yield was not ideal. Yu and his colleagues dedicated themselves to studying, consulting ancient and modern books, and going through countless experiments.
After repeated investigation, the synthesis method was improved, the reaction conditions were optimized, and the yield gradually increased. Although the process is difficult, every progress is exciting. Today, its synthesis process has achieved remarkable results. And there is a deeper understanding of its reaction mechanism.
Looking to the future, we hope to expand the application scope of this product, play a greater role in the fields of medicine, materials, etc., promote the progress and development of related industries, and contribute to the prosperity of science and technology in our country.

Toxicity Research

The taste of chemical industry is related to people's livelihood, but the nature of matter cannot be ignored. Today there is 3-Iodophenylboronic Acid, and the study of its toxicity is quite important.
We use scientific methods to investigate cautiously. Observe the structure of its molecules and analyze the signs of its reaction. In experiments, observe that it comes into contact with other things, which is harmless to living things. Take the white rat as an experiment, feed it with food containing this thing, and observe the changes in its behavior and body shape.
After years of observation, if the white rat's diet and action are as usual, the fur is shiny, and the organs are intact, the toxicity is still minimal; if there is a sign of malaise or disease, the toxicity is worrisome.
The study of toxicity should not be ignored. It is related to the safety of the living, and the industry should explore it with awe and rigor to ensure the health of everyone and the harmony of all things.

Future Prospects

I have tried to study 3-Iodophenylboronic Acid, and feel that its future prospects are quite promising. Looking at this compound, its structure is unique, or it has extraordinary use in the field of organic synthesis. It can be used as an important intermediate to assist in the construction of many complex organic molecules.
At the end of pharmaceutical research and development, it may pave the way for the creation of new drugs. With its characteristics, it may be able to precisely target diseased cells and heal diseases. And in material science, it may improve the properties of materials, such as enhancing conductivity and stability.
Over time, with the deepening of research and the advancement of technology, 3-Iodophenylboronic Acid will surely shine, adding to human well-being and technological progress, and opening up infinite possibilities in the future.

Where to Buy 3-Iodophenylboronic Acid in China?

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Frequently Asked Questions

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What are the main uses of 3-iodophenylboronic Acid?

3-Iodophenylboronic acid has a wide range of uses. In the field of organic synthesis, it is often a key reagent for building carbon-carbon bonds. It participates in the Suzuki-Miyaura coupling reaction, which is of great significance and can efficiently create various organic compounds with complex structures. It is of great value in drug development, materials science and many other fields.
In drug development, with the help of Suzuki-Miyaura coupling reaction, 3-iodophenylboronic acid can be used as a raw material to precisely synthesize compounds with novel structures, which can be used to screen lead compounds with specific biological activities and lay the foundation for the birth of new drugs. In the synthesis of many anti-cancer and antiviral drugs, 3-iodophenylboronic acid can be seen.
In the field of materials science, it is helpful for the preparation of optoelectronic materials. By coupling with specific organic halides, polymers or small molecule materials with unique optoelectronic properties can be generated. Such materials may be applied to organic Light Emitting Diodes (OLEDs), solar cells and other devices to improve their performance and efficiency.
Furthermore, 3-iodophenylboronic acid is also an important intermediate in the field of chemical research. Scientists can use various chemical modifications and transformations to explore novel chemical reaction pathways and mechanisms, and promote the development of organic chemistry. Overall, 3-iodophenylboronic acid plays an indispensable role in many fields due to its unique chemical properties, and has made significant contributions to the progress and innovation of science and technology.

What are the Physical Properties of 3-Iodophenylboronic Acid?

3-Iodophenylboronic acid, its shape is white to light yellow powder or crystal. It has a certain melting point, about 138-142 ° C. At this temperature, the substance changes from solid to liquid. This property is crucial for identification and purity analysis.
In terms of solubility, it is slightly soluble in water. Because the phenyl group and iodine atom in the molecule are hydrophobic groups, the boric acid group has a certain hydrophilicity, but the overall dissolution is limited in water. However, it is soluble in common organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), etc. During organic synthesis reactions, it can be uniformly dispersed with the help of such solvents, so that the reaction can proceed smoothly.
In terms of stability, it needs to be properly stored. Because it is more sensitive to humidity, it is prone to hydrolysis in contact with water, destroying the molecular structure and affecting its chemical activity and application effect. Therefore, it often needs to be stored in a dry environment, and it should be quickly sealed after use.
3-iodophenylboronic acid is widely used in the field of organic synthesis. Iodine atoms and boric acid groups are both active check points and can participate in many chemical reactions, such as palladium-catalyzed cross-coupling reactions, whereby carbon-carbon bonds are formed and complex organic compounds are synthesized. It is of great significance in many fields such as medicine and materials science.

What is the synthesis method of 3-iodophenylboronic Acid?

There are several common methods for preparing 3-iodophenylboronic acid. One is to use 3-iodobromobenzene as the starting material. First, 3-iodobromobenzene and magnesium chips are mixed in an inert organic solvent such as anhydrous ether or tetrahydrofuran, and the Grignard reaction occurs at a low temperature and in a nitrogen-protected atmosphere. The magnesium chips gradually react with 3-iodobromobenzene to form 3-iodophenylmagnesium bromide, a Grignard reagent. This reaction needs to be carefully maintained in a low temperature environment to prevent the growth of side reactions.
After 3-iodophenylmagnesium bromide is formed, it is slowly added dropwise to trimethyl borate. Trimethyl borate encounters 3-iodophenyl magnesium bromide, and the nucleophilic substitution reaction occurs between the two. The methoxy group of trimethyl borate is replaced by 3-iodophenyl to form trimethyl 3-iodophenylborate intermediate. After the reaction is completed, the reaction system is treated. Generally, trimethyl 3-iodophenylborate can be converted into the target product 3-iodophenylboronic acid by hydrolysis with dilute acid (such as dilute hydrochloric acid). After hydrolysis, the product is often separated and purified by means of extraction, distillation, recrystallization, etc., to obtain high-purity 3-iodophenylboronic acid.
Another method is to use 3-iodoaniline as raw material. First, 3-iodoaniline is reacted with sodium nitrite in hydrochloric acid solution for diazotization. In this process, 3-iodoaniline interacts with sodium nitrite and hydrochloric acid to form 3-iodobenzene diazoate. The diazotization reaction needs to be strictly controlled at temperature, usually at low temperature (0-5 ° C) to ensure the stability of the diazoate.
Subsequently, 3-iodobenzene diazoate and borate ester (such as trimethyl borate) are catalyzed by copper salt (such as cuprous chloride). The diazoyl group is replaced by borate ester group to form 3-iodophenylborate. After the reaction is completed, 3-iodophenylboronic acid ester is converted into 3-iodophenylboronic acid by acid hydrolysis. Finally, through separation and purification steps, pure 3-iodophenylboronic acid can be obtained. Both of these methods are common ways to prepare 3-iodophenylboronic acid, and each has its own advantages and disadvantages. In practical application, it is necessary to comprehensively consider factors such as raw material availability, cost, and product purity requirements, and choose the appropriate one.

What should be paid attention to when storing and transporting 3-iodophenylboronic Acid

3-Iodophenylboronic acid is an important reagent for organic synthesis. When storing and transporting this reagent, there are many key points that need careful attention.
Let's talk about storage first. First, ensure that the storage environment is dry. Because of its boric acid structure, it is prone to hydrolysis in contact with water, resulting in its deterioration and failure. Therefore, it should be stored in a dry, well-ventilated place, away from water sources and moisture. If conditions permit, it can be placed in a dryer and a desiccant is added to maintain the environment dry. Second, temperature control is extremely critical. This reagent is usually sensitive to temperature, and high temperature can easily promote its decomposition or other chemical reactions, so it is generally suitable to store in a low temperature environment. It is usually recommended to refrigerate at a temperature of 2-8 ° C. Third, avoid light. Light may cause photochemical reactions and affect its stability, so it should be stored in dark containers such as brown bottles.
Let's talk about transportation. First, the packaging must be tight and stable. This reagent is mostly solid powder or crystals, which can easily cause packaging damage due to bumps during transportation. Therefore, use strong packaging materials, such as glass bottles or plastic bottles, and fill them with cushioning materials such as cotton and foam to prevent collisions. Second, transportation conditions should be in line with storage requirements. If refrigerated storage is required, corresponding cold chain measures should also be taken during transportation, such as using incubators and adding ice packs, to maintain suitable low temperatures. Third, strictly follow relevant transportation regulations. Because it is a chemical, it needs to be operated according to the regulations on the transportation of hazardous chemicals to ensure the safety compliance of the transportation process and avoid harm to personnel and the environment.

3-Iodophenylboronic Acid Quality Standards

3-Iodophenylboronic acid is an important reagent in organic synthesis. Its common Quality Standards are as follows:
- ** Purity **: This is a key indicator and usually requires quite high requirements. High purity 3-iodophenylboronic acid can ensure the accuracy and efficiency of the reaction and reduce the occurrence of side reactions in organic synthesis reactions. Generally speaking, the purity needs to be above 98%, or even 99% or higher in some high-end application scenarios. It can be accurately determined by high performance liquid chromatography (HPLC). HPLC can separate and quantify the sample according to the difference in the distribution coefficient of the substance in the stationary phase and the mobile phase, and accurately obtain the purity of 3-iodophenylboronic acid.
- ** Appearance **: Under normal circumstances, it should be white to off-white crystalline powder. If the appearance color is abnormal or there are obvious impurities, or it suggests that the quality of the product is in doubt. By direct observation with the naked eye, it can be preliminarily judged whether its appearance meets the standard.
- ** Melting point **: 3-iodophenylboronic acid has a specific melting point range, about 260-264 ° C. Accurate determination of melting point can assist in determining its purity and structural integrity. When measuring melting point, the capillary method is commonly used. The sample is loaded into a capillary tube and placed in a melting point meter to slowly heat up to observe the melting temperature range of the sample.
- ** Water content **: The moisture content has a significant impact on its stability and reactivity. Excessive moisture or cause it to hydrolyze, reducing the content of its active ingredients. Usually the water content is required to be controlled at a low level, such as less than 0.5%. The Karl Fischer method can be used for determination. This method is based on the redox reaction of iodine and sulfur dioxide, and the water content in the sample is determined by electrometry or volumetric method.
- ** Heavy Metal Content **: Heavy metal impurities may cause catalytic interference to subsequent reactions, or affect the application of the product in some special fields. Common heavy metals that need to be controlled, such as lead, mercury, cadmium, etc., should be extremely low in content, generally in ppm (parts per million) level. Accurate detection can be carried out using instruments such as atomic absorption spectroscopy (AAS) or inductively coupled plasma mass spectrometry (ICP-MS).