3 Iodothioanisole
Iodobenzene

3-Iodothioanisole

Fengxi Chemical

    Specifications

    HS Code

    910247

    Chemical Formula C7H7IS
    Molar Mass 250.10 g/mol
    Appearance Colorless to light yellow liquid
    Density 1.66 g/cm³
    Boiling Point 122 - 124 °C (10 mmHg)
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Odor Characteristic odor
    Chemical Formula C7H7IS
    Molar Mass 250.10 g/mol
    Appearance Yellow to orange solid
    Melting Point 45 - 48 °C
    Boiling Point 135 - 137 °C at 15 mmHg
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Density 1.734 g/cm³
    Flash Point 128.9 °C
    Purity Typical ≥98%
    Storage Conditions Store in a cool, dry place away from light

    As an accredited 3-Iodothioanisole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 3 - iodothioanisole packaged in a sealed, chemical - resistant container.
    Storage 3 - Iodothioanisole should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly - sealed container to prevent vapor leakage. Store it separately from oxidizing agents, as they may react. This helps maintain its stability and reduces the risk of hazardous incidents.
    Shipping 3 - iodothioanisole is shipped in well - sealed containers, compliant with chemical transport regulations. Shipment involves proper labeling, ensuring protection from physical damage, and transported under conditions that maintain its stability.
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    3-Iodothioanisole
    General Information
    Historical Development
    Taste the industry of chemical industry, constantly pushing new things, there is a thing called 3 - Iodothioanisole, which is gradually emerging in the field of chemical industry.
    In the past, to explore the source of this thing, at the beginning, all the researchers worked hard for its production. At the beginning of its development, the technology is not refined, and it is difficult to obtain pure products. All kinds of attempts, or the method is biased, or the materials are not suitable, and the results are very limited.
    However, the researchers are determined, and they have not stopped because of difficulties. Delay at the end of the calendar year, and the technique is advancing day by day. The public is more refined in the selection of raw materials; in the control of the process, it is more and more strict. Finally, the method is obtained, so that the mass production of this product is expected.
    Looking at its development process, it has been difficult to explore at the beginning, and it has gradually become a scale, which really depends on the perseverance and spirit of exploration of the researchers. The way of chemical industry needs to be like this, and unremitting research can be done in the system of new things to achieve a good state and be used by the world to benefit all people.
    Product Overview
    The product description of 3-Iodothioanisole
    3-Iodothioanisole is a valuable compound in the field of organic synthesis. Its unique structure is cleverly connected by thioether groups and iodine atoms, and the phenyl ring is the base frame, giving this compound special chemical activity.
    Looking at its properties, it is mostly colorless to light yellow liquid at room temperature, with clear texture. Its physical properties are stable and its boiling point is suitable. It can be used as a good reaction substrate or intermediate in organic reaction systems. This product has certain solubility and can be well dissolved in common organic solvents such as dichloromethane and ether, providing convenience for the development of various organic reactions.
    On the stage of chemical synthesis, 3-Iodothioanisole has an extraordinary effect. Due to its high activity of iodine atoms, it is prone to nucleophilic substitution reactions, which can introduce various functional groups to build complex organic molecular structures. Thioether groups can also participate in various transformations, such as oxidation reactions, to generate derivatives with different functions. Therefore, it can be seen in many fields such as medicinal chemistry and materials science, making great contributions to the synthesis of novel compounds with specific properties.
    Physical & Chemical Properties
    3 - Iodothioanisole is an organic compound whose physical and chemical properties are of great interest. From the perspective of physical properties, this substance is in a solid state at room temperature and has a specific melting point and boiling point. Its melting point causes it to melt into a liquid state at a specific temperature, and its boiling point determines its transformation into a gaseous state at a certain temperature.
    Regarding chemical properties, the iodine atom and thioether bond in 3 - Iodothioanisole give it unique reactivity. Iodine atoms can participate in nucleophilic substitution reactions and can be replaced by other groups under appropriate reagents and conditions. Thioether bonds also exhibit certain chemical activity, or can be converted into sulfoxides or sulfones under specific oxidation conditions. The study of these physical and chemical properties is of great significance in the field of organic synthesis, which can help chemists explore new synthetic paths and lay the foundation for the preparation and application of related compounds.
    Technical Specifications & Labeling
    There is a chemical product today, called 3-Iodothioanisole. Its process specifications and identification (product parameters) are related to the quality of this product. The process specifications are the French criteria for making this product, from the selection of raw materials to the degree of synthesis. Such as the purity of raw materials, the temperature of reaction, and the duration of time, all need to be accurately grasped before it can become a good product.
    Identification (product parameters) is also very important, indicating its character, purity, and the amount of impurities contained. The appearance is clear, the purity shows its purity, and the amount of impurities indicates whether it is clean or not. This is the key to judging the quality of 3-Iodothioanisole. Strictly adhere to the process specifications and identify the product parameters, so that this product can be used in various chemical applications.
    Preparation Method
    3-Iodothioanisole is made in this product, and the raw materials are prepared first. Take an appropriate amount of thioanisole and add iodide as an aid. The two are placed in a reactor in an appropriate ratio.
    When reacting, control its temperature and pressure. At the beginning, slowly heat up, so that the raw materials are fused and the activity gradually rises. Then, maintain a constant temperature, so that the reaction proceeds in an orderly manner. In this process, carefully observe the signs of the reaction, observe the changes in its color and smell, and judge the progress of the reaction.
    After the reaction is completed, the product is separated and purified. First, the insoluble impurities are removed by filtration. After the use of distillation technology, according to the difference in boiling point, the mixed quality is divided to obtain pure 3-Iodothioanisole. This preparation method, by means of chemical principles, follows the rules of reaction, and goes through the steps of raw material compatibility, reaction regulation, and product refining to obtain the desired thing.
    Chemical Reactions & Modifications
    I will study the reaction and modification of 3-Iodothioanisole. The reaction and modification of this product are made from sulfide and iodide. Under specific reaction conditions, the two interact and undergo a series of complex chemical changes.
    As for modification, in order to increase its stability and reactivity, chemical modification is often used. For example, the introduction of specific functional groups can optimize the molecular structure. In this way, not only its physical properties can be changed, but also its chemical properties can be significantly changed.
    The reaction and modification of this product are of great significance in the field of organic synthesis. It can provide key intermediates for the preparation of new materials, drug development, etc., and promote the development and progress of related fields.
    Synonyms & Product Names
    "3 - Iodothioanisole of the same name and trade name"
    Husband 3 - Iodothioanisole, the thing of the same name. The thing of the same name, either because of the reason, or because of the name, has its official name. And the trade name, is a business that circulates and recognizes its characteristics.
    3 - Iodothioanisole, or the iodine-substituted thioanisole, is the name of the same name because of its chemical and manufacturing properties. As for the trade name, it is easy to call it in the market, or it is called by a special trade name, hoping that it can be distinguished among the same things.
    However, it is not the same name, or the name of the product, all seek clarity to avoid confusion. The things that are transformed and the uses of nature are all based on the name. Therefore, when it comes to research and application, it is necessary to observe its name, so as to understand its essence and make good use of it, so as to achieve the work of research.
    Safety & Operational Standards
    3-Iodothioanisole is also a thing that is transformed. We should be careful when handling it safely.
    Its nature is fearsome, so the operation of it must follow the rules. First of all, it is clear that this thing needs to be stored in a place that is dry, dry, and well-connected. Do not approach fire or smoke sources to prevent damage.
    When operating it, it must be protected against damage. Wear protective clothing to protect your eyes, so as to protect your eyes. Wear protective gloves, and avoid the connection of the skin. If you are not careful about the skin, wash it with a lot of water quickly, and ask for treatment. If you get into your eyes, you should also wash it with water immediately, and you should be in a hurry.
    Use this product to prevent it from steaming and harming people. After the operation, the utensils used in the cave should be cleaned and dried to prevent the left things from being damaged.
    Furthermore, there is also a certain amount of storage. In the container, it needs to be properly packaged to ensure that it is not shocked or collided. It is suitable for the degree and degree of storage, and it needs to be separated and placed to avoid the reaction of oxidation.
    Of course, 3-Iodothioanisole is useful for chemical research, but its safe operation is difficult. We cannot ignore it, and we must abide by it to ensure safety and make use of this product.
    Application Area
    3 - Iodothioanisole is also a chemical compound. Its use is outstanding in a wide range of fields.
    In the field of synthesis, this compound can be used as an important ingredient. Due to the special properties of the iodine atom, sulfur methyl, it can be used for a wide range of reactions, such as even reactions. By means of the delicate solution, the molecular skeleton of 3 - Iodothioanisole can be used, providing a powerful tool for synthesizing compounds with specific biological activities or material properties.
    In terms of research, it is also not small. Studies have shown that derivatives containing 3-Iodothioanisole elements may have significant physical activity or can be used as precursors for new research, providing new ideas and directions for conquering many diseases.
    In the field of materials science, 3-Iodothioanisole can be synthesized and modified for materials. Its special functional properties, such as the properties of materials, and light properties, etc., play an important role in high-quality materials, and promote the development of materials science.
    Research & Development
    In recent years, I have been researching many chemical substances, especially 3-Iodothioanisole. Its unique properties are quite promising in the field of organic synthesis.
    The first time I dealt with this substance, I observed its delicate structure, sulfide and iodine atoms are combined, and the chemical activity is very different. To understand its quality, I tried to measure it by various methods, analyze its spectrum, and distinguish its reaction properties.
    During the investigation, it was found that it can be a key agent in the coupling reaction. With appropriate conditions, it can make the carbon-sulfur bond and carbon-iodine bond controllable changes, paving the way for the creation of complex organic molecules.
    After repeated trials, it gradually became clear that the optimum reaction environment, temperature, solvent, and catalytic substances are all subtly related. And its side reactions are quite few, and the yield can be seen. It is a good material for organic synthesis.
    Looking to the future, I hope to borrow 3-Iodothioanisole to have deeper exploration and greater progress in the research and development of new drugs and materials, so that it can benefit various fields and become a weapon for chemical research and development.
    Toxicity Research
    I have tried to study the nature of poisons, and I have paid special attention to this thing in 3-Iodothioanisole. The nature of its poison is related to the safety of living beings, so I cannot study it carelessly.
    At the beginning, explore its chemical structure and know the wonder of its atomic connection. Then observe its phase transformation with other things and observe the signs of its reaction. During the experiment, abide by the rules to prevent it from escaping, so as not to cause disaster.
    After many inquiries, I know the reason for its poison, or it hurts the organs, or messes up the qi and blood. Although the amount is different, its harm exists.
    My intention is to study the toxicity of this thing, in order to clarify its danger and avoid harm in future generations. I hope my colleagues will study together, so that this poison will not be a disaster to the world, and the living will be safe.
    Future Prospects
    Wuguan 3 - Iodothioanisole This product has unique properties and extraordinary potential. Looking forward to the future, it may shine in the field of medicine. After in-depth research, it may be possible to use its characteristics to develop new drugs, bringing dawn for the treatment of difficult diseases.
    Furthermore, in the field of materials science, it is also expected to emerge. After clever deployment and processing, it may be able to generate new materials with excellent performance, which can be applied to key fields such as electronics and aviation, and promote scientific and technological progress.
    Although there may be many difficulties and obstacles ahead, we scientific researchers should have the determination to explore. We firmly believe that with time, we will be able to unleash its full potential, contribute greatly to human well-being, and create a better future.
    Historical Development
    3 - Iodothioanisole is also a matter of transformation. Its origin and origin can be explored. The ancient family of transformation, the nature of the object, has been involved in this compound. For the first time, few people have studied it, and they have reviewed one or two of its characteristics.
    It is a matter of time, the moon is full of talent, and the heart is full of research. Or seek the method of transformation, or study the other way around. Every time there is a problem, it is used for the purpose of research. Light promotion, 3 - The knowledge of Iodothioanisole is becoming more and more profound. The method of synthesis is exquisite by the day, and the field of application is also difficult. From the initial ignorance and exploration to the current widespread use, the development of this compound is a wonderful chapter in the history of chemistry.
    Product Overview
    3 - Iodothioanisole is also a chemical substance. Its shape or color is often light and unique. Among them, the iodine atom, sulfur atom and anisole group are cleverly intertwined, resulting in this special transformation.
    This compound is valuable in the field of synthesis. It is often used as an important factor, and it can help to produce more chemical substances. For example, in some reactions, it can be used by the activity of iodine atoms to replace other molecules, and the synthesis of new chemical substances can be built.
    Because of its special chemical properties, it is also popular in the field of materials science, and may provide new ideas for the research of new materials.
    Physical & Chemical Properties
    3 - Iodothioanisole is an important chemical substance, and its physical and chemical properties are worth studying. Looking at its physical properties, at room temperature, this substance may be in a solid state with a specific color and state, and the melting and boiling point is also a key characterization. The determination of the melting point can help us know the temperature node of its conversion from solid to liquid, and the boiling point indicates the condition of its transformation from liquid to gas.
    In terms of its chemical properties, the presence of iodine atoms and sulfur atoms in 3 - Iodothioanisole gives it unique reactivity. Iodine atoms can participate in nucleophilic substitution reactions, while sulfur atoms exhibit their chemical activity under specific conditions, or interact with electrophilic reagents. In addition, the benzene ring in its structure also affects the overall chemical properties and can participate in typical reactions of aromatics. The study of its physical and chemical properties can provide a solid foundation for related chemical synthesis and applications.
    Technical Specifications & Labeling
    There is a method for making 3-Iodothioanisole, which requires its technical specifications and identification (product parameters). To make it, first take an appropriate amount of sulfide, put it in a clean vessel, control the temperature to a moderate level, and slowly add iodide. During this time, observe the reaction state carefully, and do not overplay it. After the reaction is completed, after separation and purification, 3-Iodothioanisole is obtained.
    As for the identification (product parameters), its color should be colorless to slightly yellow, like a liquid, with a specific density, boiling point, and purity must be very high, and the impurity content must be very low. In this way, it can meet the requirements of the technical specifications and identification (product parameters) of this product, and can be used in all required places.
    Preparation Method
    In order to prepare 3-Iodothioanisole, the raw materials should be prepared first. Thioanisole and iodine are used as the main materials, and appropriate reagents need to be added. The preparation process is as follows: In a clean reaction vessel, add thioanisole and iodine in a fixed ratio, and then add an appropriate amount of auxiliary reagents. Control the temperature to a suitable degree, stir slowly, so that the various substances are fully in contact. When the reaction is completed, pay attention to its changes and fine-tune the reaction situation in a timely manner. After the reaction is completed, the product is separated and purified according to the conventional method. The catalytic mechanism is the process of promoting the reaction with auxiliary reagents, reducing the energy barrier of the reaction, so that thioanisole and iodine are more easily combined, and then 3-Iodothioanisole is obtained. Throughout the preparation, all steps need to be followed in order to obtain a high-quality product.
    Chemical Reactions & Modifications
    I try to study the chemical reaction and modification of 3-Iodothioanisole. The chemical reaction is based on the properties of sulfide and iodide. In a specific environment, control its temperature, pressure and the amount of catalyst, so that the two can combine, and then obtain this product.
    However, the initial method, the yield is not perfect, and there are a little more impurities. Thinking about it, if you want to modify it, improve its quality. It is easy to choose a new catalyst, and adjust the order. First, the sulfide is pre-treated to increase its activity.
    After this change, the yield of chemical reaction is significantly increased, and the impurities are also reduced. The quality of 3-Iodothioanisole is better than before. This shows us that we can achieve good results and optimize the quality of products in order to meet the needs of all.
    Synonyms & Product Names
    3 - Iodothioanisole is also a thing that is transformed. Its name refers to the same thing. It is also common sense that there are things in the world, and their names are different. There are names based on form, and there are functions.
    3 - Iodothioanisole, or those who have their names, have their names because of the differences in the region and the size of the person. However, when looking at their origin, they are all the same thing.
    This thing has its own characteristics and uses in the field of transformation. Those who inquire about it need to understand their respective conditions in order to grasp them. The name and whatever, must not be ignored by its name. Only by understanding its essence and understanding the name of the same, can we improve the way of research, do better, explore deeper, and use its wonders.
    Safety & Operational Standards
    3 - Iodothioanisole is an important chemical substance that needs to be explained in detail in terms of its safety and operating practices.
    For storage, be sure to choose a cool, dry and well-ventilated place. Due to its specific chemical properties, if the ambient humidity is high, it may cause deterioration; and if the temperature is too high, it may increase its chemical reactivity and cause danger. Therefore, it should be kept away from fires and heat sources and avoid direct sunlight. Storage containers should also be carefully selected, preferably those with good corrosion resistance and sealing to prevent leakage.
    Operators must wear appropriate protective equipment during operation. Such as wearing protective gloves to prevent skin contact, because it may be irritating or even corrosive to the skin; at the same time, goggles should be worn to avoid the substance splashing into the eyes, causing serious damage to the eyes. The operation process must be carried out in the fume hood to ensure that harmful gases are discharged in time, maintain the operating environment air is fresh, and reduce the risk of operator inhalation.
    If a leak unfortunately occurs, the first thing to do is to quickly evacuate the personnel in the leaked contaminated area to a safe area, and quarantine, strictly restrict personnel access. Emergency personnel need to wear professional protective equipment, do not directly contact the leak. In the event of a small amount of leakage, it can be absorbed by inert materials such as sand and vermiculite, and collected in a closed container for subsequent proper disposal; in the event of a large amount of leakage, a dike or pit should be built for containment, covered with foam to reduce steam hazards, and then transferred to a dedicated collection container for disposal by a professional organization.
    In short, the safety and operation specifications of 3-Iodothioanisole must be meticulously followed in order to ensure the safety of personnel and the environment are not damaged, and to ensure the smooth development of related work.
    Application Area
    3 - Iodothioanisole, which is quite useful in many fields. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create new drugs, participate in the construction of drug molecules through unique chemical properties, or be helpful for the treatment of specific diseases. In the field of materials science, it can improve material properties, such as enhancing material stability and conductivity, so that materials can be better used in electronic devices and other aspects. In the field of organic synthesis, it is also an important reagent, assisting chemists in synthesizing complex organic molecules, expanding the path for organic chemistry research and production. In short, 3 - Iodothioanisole has great value in many application fields and promotes the development of related sciences and industries.
    Research & Development
    Recently, I studied 3-Iodothioanisole. It is unique, related to various fields of chemical industry, and has a wide range of prospects, so I studied it in detail.
    Begin to explore its craftsmanship. After many tests, I adjusted various parameters, such as temperature, pressure and the ratio of agents, to obtain the best method. At the beginning, the yield was not as expected, and there were many impurities. However, I was not discouraged, and I carefully inspected the process to investigate the crux of the matter. After obtaining a new formula, the yield gradually increased, and the quality became purer.
    Restudy its use. In organic synthesis, it can be used as a key reagent to introduce specific groups and expand reaction pathways. Try again in material preparation, hoping to add novelty. After repeated attempts, some results have been obtained, and the material properties have improved.
    Although progress has been made today, the road ahead is still difficult. In the future, it will be deeply studied, its use will be expanded, and its methods will be improved. Phase 3 - Iodothioanisole shines brightly in the field of chemical industry and promotes the prosperity of this industry.
    Toxicity Research
    3-Iodothioanisole This chemical product, the study of toxicity, is quite important.
    Watching the past, all kinds of chemical products, or because of their toxicity, have caused harm to living things. 3-Iodothioanisole Although it has not been widely spread, it is impossible to ignore it. To explore its toxicity, we need to follow the scientific method, test it in all things, observe its reaction, and observe its changes.
    After many trials, we can explore its interaction with living things, observe the changes of cells, and measure the signs of physiology. If there is any abnormality, we can know the toxicity. Although it is only 200 words, the investigation of toxicity has a long way to go. We should make unremitting research to understand its benefits for the world and ensure the well-being of all living beings.
    Future Prospects
    Husband 3 - Iodothioanisole is also a thing of transformation. There is nothing to be said about the future prospects of this compound.
    This compound is unique, and it may have new applications in multiple domains. It has not been developed yet, or it can be used in research and development, which can help create new technologies and add strength to the treatment of diseases. Or in the field of materials, it will become the cornerstone of new materials. Materials with unique properties are widely used.
    Furthermore, the method of synthesis is also expected to be innovative. Scientists may be able to explore more efficient and safe ways, reduce energy consumption and reduce pollution. In this way, the amount cannot be increased, and it can be more suitable for the concept of colorization.
    In, 3 - Iodothioanisole's unseen landscape is like the dawn, full of hope. We researchers, diligently explore, in order to unearth its greatest potential for the benefit of the world.
    Where to Buy 3-Iodothioanisole in China?
    As a trusted 3-Iodothioanisole manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 3-Iodothioanisole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 3-iodothioanisole?
    3-Iodothioanisole is also a chemical substance, and the Chinese name is 3-iodothioanisole. Its main use is wide, and it plays an important role in the field of organic synthesis.
    In organic synthesis reactions, 3-iodothioanisole often acts as a key intermediate. Because its molecular structure contains iodine atoms and thiomethyl groups, these two give the compound unique chemical activity. Iodine atoms are active and easily participate in nucleophilic substitution reactions. Chemists can attack iodine atoms with nucleophiles to make them leave, and then introduce various functional groups to build complex organic molecular structures. For example, in the palladium-catalyzed cross-coupling reaction, 3-iodothioanisole can react with nucleophiles containing alkenyl and aryl groups to form carbon-carbon bonds, providing an effective path for the synthesis of polyaryl compounds or alkenyl thioether-containing compounds. Such compounds have potential applications in pharmaceutical chemistry and materials science.
    Furthermore, the presence of thiomethyl groups also affects the electronic properties and spatial structure of molecules. It can be used as a positioning group to guide subsequent reaction check point selectivity, and help to synthesize organic compounds with specific structures and functions. In the process of drug development, through structural modification and derivatization of 3-iodothioanisole, compounds with unique biological activities may be obtained, laying the foundation for the creation of new drugs.
    In the field of materials science, organosulfide materials synthesized by 3-iodothioanisole may exhibit special electrical and optical properties, and may have application potential in organic semiconductors, luminescent materials, etc., and can be used to prepare organic field effect transistors, organic Light Emitting Diodes and other optoelectronic devices.
    What are the physical properties of 3-iodothioanisole?
    3-Iodothioanisole, that is, 3-iodoanisole, is a kind of organic compound. Its physical properties are as follows:
    Looking at its appearance, under room temperature and pressure, it is a colorless to light yellow liquid state, with a clear and transparent texture. Its color and state are intuitive characteristics.
    Smell its smell, it has a special aromatic smell, but this smell is not a simple pleasant fragrance, nor a pungent and intolerable odor, but a unique smell of organic compounds.
    When it comes to the melting point, the melting point is about -18 ° C, and the boiling point is between 270-272 ° C. This melting point data shows that 3-iodoanisulfide exists stably in a liquid state at room temperature, solidifies at low temperature, and boils at high temperature.
    In addition to density, its density is higher than that of water, about 1.73 g/cm ³. This means that if 3-iodoanisulfide is placed in the same container as water, it will sink in the lower layer of water.
    In terms of solubility, 3-iodoanisulfide is insoluble in water, but easily soluble in common organic solvents such as ethanol, ether, chloroform, etc. This solubility characteristic is closely related to the structure and polarity of water molecules and organic solvent molecules.
    The vapor pressure of 3-iodoanisulfide is low, and the volatility is relatively weak. At room temperature, its volatilization rate in air is slow, and it is not easy to quickly escape into the environment.
    The refractive index of this compound is also a specific value, about 1.633-1.637. As a characteristic constant of the substance, the refractive index can be used to identify 3-iodoanisulfide, and it is also helpful to determine its purity.
    The above physical properties are of great significance for understanding the characteristics, identification methods and applications of 3-iodoanisulfide in chemical, pharmaceutical and other fields.
    What are the chemical properties of 3-iodothioanisole?
    3-Iodothioanisole, that is, 3-iodothioanisole. Its chemical properties are quite important and have many applications in the field of organic synthesis.
    This compound has unique reactivity. As far as nucleophilic substitution is concerned, the activity of iodine atoms is high, because the tendency of iodine to leave is quite large. When encountering nucleophiles, iodine atoms are easily replaced to form new carbon-nucleophilic bonds. For example, if there are nucleophiles containing nitrogen, oxygen or sulfur, nucleophilic substitution with 3-iodothioanisole can occur smoothly, resulting in a series of derivatives with different functional groups.
    Its sulfur methyl group also has special properties. The solitary pair electrons on the sulfur atom give it a certain nucleophilicity. Although it is slightly slower than the reaction involving the iodine atom, it can react with the electrophilic reagent under appropriate conditions. And the sulfur methyl has an effect on the electron cloud distribution of the benzene ring, which changes the density of the electron cloud of the benzene ring and the para-position, which affects the electrophilic substitution reaction on the benzene ring.
    In the oxidation reaction, the sulfur atom can be oxidized. Under moderate oxidation conditions, sulfoxide products can be formed; if the oxidation conditions are more severe, it is further converted to sulfone.
    And because of its iodine and thiomethyl, 3-iodothioanisole can be used as an important substrate in the metal-catalyzed coupling reaction For example, palladium-catalyzed coupling reactions can be coupled with boric acids containing alkenyl and aryl groups to form carbon-carbon bonds, which are crucial in the synthesis of complex organic molecules. And iodine atoms and thiomethyl groups can cooperate to make the reaction more selective and active, providing organic synthesis chemists with many strategies to construct organic compounds with diverse structures.
    What is the synthesis method of 3-iodothioanisole?
    The synthesis of 3-iodothioanisole covers the important tasks of chemical preparation. There are many methods, one of which is described here. Thioanisole is used as the starting material and the target product can be obtained by halogenation.
    Take an appropriate amount of thioanisole first and place it in a clean reaction vessel. This vessel must be dry and able to withstand the reaction conditions. Then add an appropriate amount of halogenating reagent, such as iodine elemental substance ($I_2 $), and add an appropriate catalyst, such as iron powder or ferric chloride. The catalyst can promote the reaction and increase its rate.
    When reacting, it is often necessary to control the temperature. Generally speaking, mild heating is appropriate to maintain the reaction system within a specific temperature range. If the temperature is too high, or side reactions occur, the product is impure; if the temperature is too low, the reaction will be slow and time-consuming. During the reaction process, pay close attention to the changes of the system and observe the changes in its color and state.
    When the reaction reaches the expected level, that is, after appropriate detection methods, such as thin layer chromatography (TLC), it is confirmed that most of the raw materials have been converted into products, the reaction can be terminated. Subsequent treatment is also crucial. The reaction mixture is cooled first, and then separated and purified. The product is often extracted by extraction with a suitable organic solvent, such as dichloromethane. After that, impurities are removed by washing, drying, distillation or column chromatography, and pure 3-iodothioanisole can be obtained.
    However, the synthesis method is not only at this end, but also has other ways, which can be selected according to factors such as actual needs, raw material availability and cost. This synthesis method is only a common example. In chemical practice, chemists are constantly seeking better methods to increase yield, reduce energy consumption and side reactions, and achieve the environment of green chemistry.
    3-Iodothioanisole What to pay attention to when storing and transporting
    3-Iodothioanisole is an organic compound. When storing and transporting, the following numbers should be paid attention to:
    First, about storage. This compound should be placed in a cool, dry and well-ventilated place. Because it is more sensitive to heat, high temperature is easy to decompose or cause other chemical reactions, so it should be kept away from fire and heat sources and avoid direct sunlight. If the storage temperature is too high, the structure of 3-iodothioanisole may be damaged, which will affect its quality and performance. In addition, it is necessary to ensure that the storage environment is dry, because it may react with moisture, and if it is damp in contact with water, it may cause deterioration. When storing, it should also be sealed to prevent contact with oxygen, carbon dioxide and other gases in the air. Oxygen may oxidize it, and carbon dioxide may also participate in certain chemical reactions, thereby changing its chemical properties.
    Second, in terms of transportation. The transportation process must ensure that the packaging is complete and well sealed. Packaging materials should have good compression and shock resistance to prevent package damage due to collision and vibration, resulting in leakage of 3-iodothioanisole. At the same time, transportation vehicles need to be equipped with corresponding fire equipment and leakage emergency treatment equipment to deal with possible unexpected situations. Moreover, in accordance with relevant regulations, transportation should be carried separately from oxidants, acids, alkalis and other substances, because 3-iodothioanisole may react violently with these substances, causing danger. In addition, transportation personnel should also be familiar with the characteristics and emergency treatment methods of 3-iodothioanisole, and regularly check the condition of the goods during transportation to ensure the safety of transportation.