3-Nitroiodobenzene

Fengxi Chemical

Specifications

HS Code	645309
Chemical Formula	C6H4INO2
Molar Mass	249.006 g/mol
Appearance	Yellow solid
Melting Point	94 - 96 °C
Boiling Point	281 - 282 °C
Density	1.952 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, ether
Hazard Class	Harmful if swallowed, inhaled or in contact with skin; may cause irritation

As an accredited 3-Nitroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 3 - nitroiodobenzene packaged in a sealed, chemical - resistant container.
Storage	3 - nitroiodobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. It should be kept in a tightly closed container to prevent contact with air and moisture. Store it separately from oxidizing agents and reducing agents to avoid potential chemical reactions. Adhere to local safety regulations for chemical storage.
Shipping	3 - nitroiodobenzene is a chemical that may have specific shipping regulations due to its nature. It should be packaged securely in suitable containers, following all hazardous material shipping guidelines to ensure safe transportation.

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General Information

Historical Development

3-Nitroiodobenzene is also an organic compound. At the beginning of its historical development, chemists began to pay attention to this unique molecule when exploring the synthesis of various substances. In the past, the method of organic synthesis was still simple, and it was quite difficult to obtain 3-Nitroiodobenzene. Chemists used their ingenuity and tried repeatedly to explore various reaction paths.
Initially, or tried to add nitro to the conventional halogenation reaction, but the effect was not satisfactory. Later, with the improvement of chemical theory, the control of reaction conditions, such as temperature and catalyst, made the synthesis efficiency gradually increase. After years of delay, many chemists have continued to improve the synthesis process, making the preparation of 3-Nitroiodobenzene more mature and gaining a place in the field of organic synthesis, laying an important foundation for the development of subsequent organic chemistry.

Product Overview

3 - Nitroiodobenzene is an organic compound. It is a light yellow crystal with a special odor. The melting point is quite low, between 37 and 39 degrees Celsius, and the boiling point is about 276 degrees Celsius.
This compound is widely used in the field of organic synthesis. It is often used as an intermediate to prepare various drugs, dyes and other fine chemicals. In its structure, both nitro and iodine atoms have active chemical properties and can participate in many chemical reactions, such as nucleophilic substitution reactions.
The preparation method can be obtained by the nitration reaction of iodobenzene. During the reaction process, careful temperature control and appropriate reaction conditions should be selected to ensure the purity and yield of the product.
When using this compound, it is also necessary to pay attention to its safety. Due to its certain toxicity and irritation, strict safety procedures must be followed during operation, and protective measures must be taken to avoid harming people and the environment.

Physical & Chemical Properties

3 - Nitroiodobenzene is an organic compound, and its physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, this substance is often in a solid state, with a specific melting point and boiling point. The melting point is the critical temperature at which the substance changes from solid to liquid state; the boiling point is the key temperature at which the liquid state changes to gas state.
Discussing chemical properties, the nitro and iodine atoms in 3 - Nitroiodobenzene give it unique reactivity. Nitro has strong electron absorption, which can affect the electron cloud density of the benzene ring and cause changes in the electrophilic substitution activity of the benzene ring. Iodine atoms can also participate in many chemical reactions, such as nucleophilic substitution reactions. Due to its special structure, 3-Nitroiodobenzene is often used as a key intermediate in the field of organic synthesis, laying the foundation for the synthesis of many complex organic compounds, and is an important object of organic chemistry research.

Technical Specifications & Labeling

3 - Nitroiodobenzene is an important compound in organic synthesis. The preparation process first uses iodobenzene as the starting material, and in an appropriate reaction vessel, under the action of a specific temperature and catalyst, nitrification reaction occurs with the mixed acid of concentrated nitric acid and concentrated sulfuric acid. During the reaction, parameters such as temperature, acid ratio and reaction time need to be precisely controlled to prevent side reactions from occurring.
The identification of the product can be determined by a melting point tester, which is compared with the standard value; its characteristic functional groups can also be analyzed by infrared spectrometer. The stretching vibration peak of the nitro group and the related vibration peak of the benzene ring are all important bases; the structure can also be confirmed by nuclear magnetic resonance spectrometer according to the chemical shifts and coupling constants of hydrogen and carbon spectra. At the same time, high-performance liquid chromatography can be used to determine the purity of the product to ensure that the product quality meets the corresponding standards and meets the needs of subsequent experiments or industrial applications.

Preparation Method

The method of making 3-Nitroiodobenzene is related to the raw materials and production process, reaction steps and catalytic mechanism. Take iodobenzene as the raw material, and mix the acid with concentrated nitric acid and concentrated sulfuric acid. The dosage of the two is precisely controlled and the ratio is appropriate. Slow injection of iodobenzene into the mixed acid, stir well, and control the temperature in a specific range to prevent side reactions. This step is the beginning of nitrification. Nitrate ions are used as electrophilic reagents to attack the iodobenzene ring, rearrange through the electron cloud to form an intermediate, and then deproton to obtain 3-Nitroiodobenzene crude product.
Crude products are purified by neutralization, washing with water, extraction, and distillation to remove impurities and improve purity. Catalyst can promote the reaction rate, reduce energy barrier, such as Lewis acid, which interacts with nitric acid to enhance electrophilic activity and increase yield. Fine operation and strict compliance with procedures can produce good product 3-Nitroiodobenzene.

Chemical Reactions & Modifications

The beauty of chemistry lies in the endless change, and the matter of reaction and modification is particularly crucial. In today's discussion of the product of 3-Nitroiodobenzene, the chemical reaction and modification of it can be investigated quite a bit.
In past studies, the reaction was often based on specific methods, but if you want better properties, you must think about changes. The conditions of the reaction, such as temperature and the amount of reagents, can affect the fruit. Or adjust the temperature to make the molecular movement suitable, promote the speed of the reaction, and increase the purity of the product.
As for modification, other groups can be introduced into its structure and its properties to meet the needs of diversity. If you add a certain base, change its polarity, change its solubility, or increase its stability to avoid the risk of its variability.
If you want to clarify its details, you should carefully investigate all changes, test them repeatedly, and find the best way to make the properties of 3-Nitroiodobenzene products reach an ideal state, which is a chemical advance and adds bricks and mortar.

Synonyms & Product Names

3 - Nitroiodobenzene, the synonym and trade name of this thing, we need to explore in detail. In the field of chemical research, knowing its synonyms and trade names is related to the accuracy and depth of research.
The ancient books of the past, although 3 - Nitroiodobenzene is not directly described, the names of chemical substances often vary with the changes of the times. Or there are ancient names, which have evolved into today's scientific names through the years.
Its synonyms, or due to the habits of different regions and schools, have slightly different titles. And commodity names are mostly determined by merchants according to market and product characteristics.
Our generation should be rigorous, check all the literature, visit all the parties, and explore the synonyms and trade names of 3-Nitroiodobenzene, so as to be accurate and not confused in chemical research and application, and lay a solid foundation for academic refinement and industrial practice.

Safety & Operational Standards

3 - Nitroiodobenzene is a chemical substance, which is crucial for its safety and operating practices.
Safety is the top priority when preparing and using 3 - Nitroiodobenzene. This substance may be toxic and dangerous, and the experimenter must strictly follow safety procedures. First, appropriate protective equipment must be worn, such as laboratory clothes, gloves and goggles, to prevent skin contact and splashing into the eyes. Second, the operation should be carried out in a well-ventilated environment, preferably in a fume hood, to avoid the accumulation of harmful gases and endanger the health of the experimenter.
Furthermore, the operating standards cannot be ignored. When weighing 3-Nitroiodobenzene, be sure to use a precise weighing instrument to ensure accurate dosage. Due to wrong dosage or experimental deviation, it may even cause danger. During the dissolution or reaction process, the temperature, time and stirring rate should be strictly controlled according to the reaction requirements. When heating, do not raise the temperature suddenly, but do it slowly to prevent local overheating from causing the reaction to get out of control.
Storage of 3-Nitroiodobenzene is also exquisite. It should be placed in a cool, dry and ventilated place, away from ignition sources and oxidants. Because of its certain chemical activity, improper storage or deterioration and danger. At the same time, it should be properly marked, indicating key information such as name, nature and hazard, for easy access and management.
In terms of waste treatment, the used 3-Nitroiodobenzene and related solutions should not be dumped at will. They must be collected in accordance with chemical waste treatment regulations and handed over to professional institutions for treatment to avoid polluting the environment.
In short, the treatment of 3-Nitroiodobenzene should strictly abide by safety and operating standards from operation to storage and disposal to ensure the safety of the experiment and achieve the expected results.

Application Area

3 - Nitroiodobenzene is also an important chemical substance. Its application is not limited. In the research and development, it is often used in important synthesis. It can be synthesized by specific chemical reactions and multi-compound interactions to create chemical compositions with special effects.
In the field of materials science, it also has an extraordinary performance. Its material synthesis can improve the physical properties of materials, such as improving the quality and performance of materials. For example, some polymer reactions can obtain new functional materials with excellent performance, which can be used in sub-devices, optical components, etc.
In addition, in the field of synthesis, 3 - Nitroiodobenzene can be filled with chemical compounds, which can be used to build the molecular properties of the material. With its unique chemical properties, it can lead to a series of reactions, such as nuclear substitution, even reactions, etc., which can enrich the development of chemical compounds and promote the development of chemical synthesis.

Research & Development

I am in the field of chemistry, and I am good at studying. Recently, the object I studied is 3-Nitroiodobenzene. This material is unique and has extraordinary potential in many fields such as chemical industry and medicine.
In order to clarify its properties, I have tried to explore it in many ways. First observe its chemical properties, observe its reaction under different conditions, and study the influence of various factors on its reaction. Then test its physical properties, measure its melting point, dissolution, etc.
After months of work, I have made some gains. In the synthesis method, find a new way to increase its yield, save raw materials and reduce pollution. However, the road ahead is still difficult, and in order to promote the results widely, it is still necessary to study its safety and stability in detail.
I will work tirelessly, hoping to better understand the mystery of 3-Nitroiodobenzene, to promote its ability in various industries, and to contribute to the progress of the world.

Toxicity Research

Since modern times, chemical refinement has come into being, and various compounds have come into being. Looking at 3-Nitroiodobenzene today, the study of its toxicity is quite important.
We carefully observe its properties, and handle it cautiously during experiments. Observe its sympathies with other things, and observe its signs of change. See it in a specific environment, or produce strange changes, and it has an impact on surrounding organisms.
After repeated investigations, we know the importance of its toxicity. It is in the body of organisms, or the order of metabolism is disorderly, and the ability to disturb the viscera. Although it is used in some fields, the risk of toxicity should not be ignored.
Therefore, the study of the toxicity of this substance should be done with scientific methods and rigorous heart. Those who use this object for future generations should understand its advantages and disadvantages, avoid its harm, ensure the safety of all living beings, and protect the tranquility of the environment.

Future Prospects

I have dedicated myself to the product of 3-Nitroiodobenzene. This substance, a treasure of chemistry, contains endless potential. Although it is known today, it is only its appearance, but I am full of enthusiasm for its future development.
Looking at its nature, its structure is exquisite, and its response is specific, it may be able to open up a new path in the field of medicine. Based on it, it is not a lie to develop special drugs to treat difficult diseases in the world. And in material science, it is also expected to shine brightly, making high-strength and special materials for use in all kinds of high-end places.
Although the road ahead is long and there are many thorns, but I uphold my perseverance and will never give up. It is hoped that with unremitting efforts, we can gain a glimpse of its secrets, so that this product can be used in the future, for the well-being of mankind, to build unparalleled achievements, and to show infinite brilliance, so as to demonstrate the great achievements of chemical research.

Where to Buy 3-Nitroiodobenzene in China?

As a trusted 3-Nitroiodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 3-Nitroiodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 3-nitroiodobenzene?

3-Nitroiodobenzene is 3-nitroiodobenzene, which is widely used. It plays an important role in the field of organic synthesis.
Because of its unique chemical activity in the structure of nitro and iodine atoms, it can be used as a key intermediate for the preparation of many complex organic compounds. Taking medicinal chemistry as an example, many biologically active molecules often rely on 3-nitroiodobenzene as the starting material in the synthesis process. Through appropriate chemical reactions, its nitro and iodine atoms can be modified to construct structural units with specific pharmacological activities, and then synthesize new drugs.
In the field of materials science, 3-nitroiodobenzene also has important applications. It can participate in the synthesis of polymer materials, introducing it into the main chain or side chain of the polymer through chemical reactions, giving the material specific properties, such as improving the electrical properties, optical properties or thermal stability of the material.
Furthermore, in the field of dye chemistry, 3-nitroiodobenzene can be used as a raw material for the synthesis of special structural dyes. Through functional group transformation and modification, dyes with unique colors and properties are prepared to meet the needs of different industries for dyes.
In summary, 3-nitroiodobenzene, with its unique chemical structure, plays an indispensable role in many fields such as organic synthesis, medicinal chemistry, materials science, and dye chemistry, providing an important foundation for the synthesis of many compounds and the development of new materials.

What are the physical properties of 3-nitroiodobenzene?

3-Nitroiodobenzene is an organic compound. It has unique physical properties, which are related to the properties of this substance. Let me describe it in detail for you.
Looking at its properties, under normal conditions, 3-nitroiodobenzene is in a light yellow crystalline state. The characteristics of this color state can be observed by the naked eye. Its light yellow appearance is one of its physical properties.
When it comes to the melting point, the melting point is about 38-42 ° C, and the boiling point is about 285 ° C. The melting point is established. At a certain temperature, this substance can gradually melt from a solid state to a liquid state. This temperature range is its melting point range. The boiling point is also a key property. When it reaches 285 ° C, 3-nitroiodobenzene changes from a liquid state to a gaseous state. The nature of this melting point is an important guide in the separation, purification and application of substances.
Solubility is also an important physical property. 3-nitroiodobenzene is slightly soluble in water, but soluble in many organic solvents, such as ethanol, ether, benzene, etc. Slightly soluble in water, because water is a polar solvent, and the molecular polarity of 3-nitroiodobenzene is different from that of water, according to the principle of "similar miscibility", it is difficult to dissolve in water. On the contrary, it has better solubility in organic solvents such as ethanol, ether, and benzene, because the molecular structure and polarity of these organic solvents are more compatible with 3-nitroiodobenzene.
In addition, the density of 3-nitroiodobenzene is also one of the important physical properties. Its density is higher than that of water. If it is co-placed with water in a container, it will sink in the lower layer of water due to its high density. This density characteristic is of great significance in some processes involving liquid-liquid separation or mixing.
To sum up, the physical properties of 3-nitroiodobenzene, such as its light yellow crystalline appearance, specific melting and boiling point, solubility and density, together constitute its unique physical properties, which are crucial for its application and treatment in the fields of organic synthesis, chemical production and other fields.

What are the chemical properties of 3-nitroiodobenzene?

3 - nitroiodobenzene, Chinese name 3 - nitroiodobenzene. This is a benzene compound with chemical properties. It is described as follows:
Its molecule contains nitro (-NO ³)
The iodine atom also absorbs the molecular group, but the benzene is connected, and it can supply benzene through p-π. This effect increases the density of the benzene sub-cloud, especially in the negative and negative positions.
3-nitroiodobenzene can be reacted. In the nuclear substitution reaction, the iodine atom has high activity, and can be replaced by nuclear substances such as alcohols and amines to form new compounds. For example, the reaction of alcohol can generate aryl ethers; the reaction of amine can obtain aromatic amine derivatives.
In terms of proto-reaction, nitro groups can be obtained by specific proto-amino groups such as powders, acids, and catalysts, etc., to obtain 3-aminoiodobenzene, which is an important step in the synthesis of polymers, dyes, and organic materials.
In addition, 3-nitroiodobenzene can be used for gold-catalyzed antidotes, such as cross-catalyzed antidotes, which can contain alkenyl groups, aryl groups, etc., and build carbon-carbon molecules. The synthesis of more complex molecules has a wide range of uses in the field of synthesis.

What are the synthesis methods of 3-nitroiodobenzene?

The synthesis method of 3-nitroiodobenzene has been studied by many scholars in the past, and now I will describe it in detail.
First, nitrobenzene can be started. First, iodine and nitrobenzene are obtained by electrophilic substitution with the help of specific catalysts, such as ferric chloride or mercury sulfate. In this process, the nitro group is the meta-site group, and the iodine atom is easily introduced into the nitro meta-site to form 3-nitroiodobenzene. However, it is necessary to pay attention to the reaction conditions. Temperature and catalyst dosage are all related to the yield and purity of the product. If the temperature is too high, it may cause side reactions, resulting in complex and difficult purification of the product; improper dosage also affects the reaction rate and process.
Second, aniline can also be obtained as a raw material The aniline is acetylated to protect the amino group, and then the nitro group is introduced into the amino interposition through nitration reaction. After hydrolysis to remove the acetyl group, diazotization and reaction with potassium iodide, and finally converted into 3-nitroiodobenzene. Although this path is a little complicated, it can effectively control the position of the substituent and improve the selectivity of the product.
Third, the coupling method of halogenated aromatics. If there is a suitable halogenated nitrobenzene, it can be synthesized by coupling reaction with iodizing reagents and catalyzed by transition metal catalysts such as palladium. This method is efficient and atom-economical, but the precise control of catalyst cost and reaction conditions is the key, which is related to the industrial application prospect.
There are many methods for synthesizing 3-nitroiodobenzene, each with its own advantages and disadvantages. Experimenters need to carefully choose the appropriate method according to their own conditions, such as raw material availability, cost considerations, equipment status, etc., in order to obtain this compound efficiently.

What are the precautions for 3-nitroiodobenzene in storage and transportation?

3-Nitroiodobenzene is an organic compound, and many matters must be paid attention to when storing and transporting it.
The first word of storage, this substance should be stored in a cool and ventilated warehouse. Because it is easy to decompose when heated, the temperature of the warehouse should not be too high to prevent danger. And it is necessary to keep away from fire and heat sources, and strictly prohibit fireworks, because 3-nitroiodobenzene is exposed to open flames, hot topics, or the risk of combustion and explosion. In addition, it should be stored separately from oxidants, reducing agents, alkalis, etc., and must not be mixed to prevent mutual reaction and cause accidents. When storing, the package must also be sealed to avoid moisture, because it may be sensitive to humidity, after moisture or affect its quality, and even produce dangerous reactions.
As for transportation, it is necessary to ensure that the packaging is complete and the loading is safe before transportation. During transportation, the speed of the vehicle should not be too fast, and sudden braking should be avoided to prevent damage to the packaging. Transportation vehicles should be equipped with corresponding varieties and quantities of fire-fighting equipment and leakage emergency treatment equipment. During transportation, it should be protected from exposure to the sun, rain, and high temperature. If transported by rail, it is not allowed to stop in residential areas and densely populated areas.
In short, in the storage and transportation of 3-nitroiodobenzene, every link needs to be treated with caution, and relevant regulations and operating procedures should be strictly followed to ensure the safety of personnel and the environment.