3 Pyridinecarboxylic Acid 1 2 Dihydro 5 Iodo 2 Oxo
Iodobenzene

3-pyridinecarboxylic Acid, 1,2-dihydro-5-iodo-2-oxo-

Fengxi Chemical

Specifications

HS Code

338932

Chemical Formula C6H4INO3
Molar Mass 265.005 g/mol
Chemical Formula C6H4INO3
Molar Mass 265.005 g/mol
Solubility In Water Limited solubility expected due to non - polar parts in the molecule
Pka For the carboxylic acid group, likely around 4 - 5 typical for pyridine - carboxylic acids
Stability Stable under normal conditions, but may be sensitive to light and strong oxidizing agents due to the presence of iodine
Reactivity Can react with bases due to the carboxylic acid group, and iodine can participate in substitution reactions
Name 3-pyridinecarboxylic Acid, 1,2-dihydro-5-iodo-2-oxo-
Molecular Formula C6H4INO3
Molecular Weight 265.005
Appearance Solid (predicted)
Boiling Point 446.7±45.0 °C at 760 mmHg (predicted)
Melting Point 250 - 252 °C (lit.)
Density 2.139±0.06 g/cm3 (20 °C, 760 mmHg) (predicted)
Pka 3.94±0.20 (Predicted)
Solubility Soluble in DMSO (Slightly), Methanol (Slightly)
Refractive Index 1.682 (predicted)
Flash Point 224.0±28.7 °C (predicted)
Chemical Formula C6H4INO3
Molecular Weight 265.005 g/mol
Appearance Solid (likely, based on common organic compounds of this type)
Solubility In Organic Solvents May be soluble in polar organic solvents like DMSO, DMF due to polar functional groups
Stability May be sensitive to light and air due to presence of iodine and carbonyl group
Packing & Storage
Packing 100g of 3 - pyridinecarboxylic Acid, 1,2 - dihydro - 5 - iodo - 2 - oxo in sealed chemical - grade bags.
Storage Store 3 - pyridinecarboxylic Acid, 1,2 - dihydro - 5 - iodo - 2 - oxo - in a cool, dry place away from heat and ignition sources. Keep it in a tightly sealed container to prevent moisture absorption and exposure to air. Avoid storing near incompatible substances, as this compound may react. Store in a location accessible only to trained personnel.
Shipping 3 - pyridinecarboxylic Acid, 1,2 - dihydro - 5 - iodo - 2 - oxo - is shipped in well - sealed containers. Packaging is designed to prevent leakage. Shipment adheres to strict chemical transportation regulations to ensure safety during transit.
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3-pyridinecarboxylic Acid, 1,2-dihydro-5-iodo-2-oxo- 3-pyridinecarboxylic Acid, 1,2-dihydro-5-iodo-2-oxo- 3-pyridinecarboxylic Acid, 1,2-dihydro-5-iodo-2-oxo-
General Information
Frequently Asked Questions
3 - pyridinecarboxylic Acid, 1, 2 - dihydro - 5 - iodo - 2 - oxo - what is the main use
3 + - + pyridinecarboxylic acid, 1,2-dihydro-5-iodine-2-oxygen, this substance has a wide range of uses. In the field of medicine, it is often a key intermediate, helping to synthesize a variety of drugs. Due to its unique chemical structure, it can participate in specific reactions, construct compounds with biological activity, or lay the foundation for the development of new drugs to treat certain diseases.
In the field of organic synthesis, as a special chemical raw material, it can participate in the construction of many complex organic molecules. With its specific functional group characteristics, chemists can ingeniously design reaction pathways to prepare organic materials with specific properties and structures, which play an important role in the development of materials science.
In terms of scientific research and exploration, it has become an important object for studying the mechanism of organic reactions. Scientists observe the various reaction processes they participate in, deeply analyze the laws of reactions, and gain insight into the nature of chemical changes, providing a key basis for the enrichment and improvement of organic chemistry theory, promoting the continuous development of chemistry, and helping people to understand and manipulate the transformation and properties of substances at the molecular level.
3 - pyridinecarboxylic Acid, 1, 2 - dihydro - 5 - iodo - 2 - oxo - what are the physical properties
3 + -Pyridinecarboxylic acid, 1, 2-dihydro-5-iodine-2-oxygen compound, the physical properties of this substance are as follows.
Its appearance or a specific color and shape. Generally speaking, it may be a crystalline solid, which can be orderly deposited into a crystalline state under suitable conditions due to the regular arrangement of atoms in the molecule. The color of this substance is different from that of ordinary pyridinecarboxylic acid derivatives due to the introduction of iodine atoms. The electronic structure of the iodine atoms makes it yellowish to light brown.
When it comes to the melting point, due to the complex intermolecular forces, including functional groups such as iodine atoms and carbonyl groups, which enhance the interaction between molecules, the melting point may be in a relatively high range, and it is speculated that it may be between 150 ° C and 250 ° C.
In terms of solubility, given the basicity of the pyridine ring and the acidity of the carboxyl group, it may have a certain solubility in polar solvents. In water, carboxyl groups can form hydrogen bonds with water molecules, but the hydrophobicity of iodine atoms and benzene rings limits the solubility in water, so the solubility in water may be limited; in organic solvents such as alcohols, due to the similar principle of compatibility, and alcohols can form hydrogen bonds with carboxyl groups, the solubility may be better than that of water.
Density is also an important physical property. Due to the presence of iodine atoms in the molecule, the relative mass of iodine atoms is large, resulting in a higher density than that of pyridinecarboxylic acid derivatives without iodine, or between 1.8 and 2.2 g/cm ³. The specific value depends on the exact molecular structure and crystal form.
Furthermore, it has a certain refractive index. The electron cloud distribution and chemical bond characteristics in the molecule cause light to refract when passing through. The refractive index can reflect the influence of the internal structure of the molecule on light propagation. Under specific conditions, the refractive index may be between 1.6 and 1.7, which can provide a basis for the identification of this substance.
In summary, 3 + -pyridinecarboxylic acid, 1,2-dihydro-5-iodine-2-oxygen, with its unique physical properties, lays the foundation for research and application in related fields.
3 - pyridinecarboxylic Acid, 1, 2 - dihydro - 5 - iodo - 2 - oxo - what are the chemical properties
5-Iodine-1,2-dihydro-2-oxo-3-pyridinecarboxylic acid, which has strange physical properties and is common to acids. It can be weakly ionized in water and release hydrogen ions, which is acidic. Its structure is unique. The iodine atom is connected to the pyridine ring, and there are dihydrogen and oxygen groups on the ring, which makes its chemical activity unique.
When it comes to the reaction characteristics, carbonyl groups can be involved in many reactions. In the case of nucleophiles, carbonyl carbons can undergo addition reactions when attacked by nucleophiles. They can form esters with alcohols and amides with amines. The activity of iodine atoms should not be underestimated. They can participate in the substitution reaction and be replaced by other groups, and then derive a variety of compounds.
Its solubility is quite special, because it contains carboxyl groups, it has a certain solubility in polar solvents such as water, but the pyridine ring and iodine atom increase its hydrophobicity, resulting in its solubility is not very high. When heated, the molecular structure may change, decompose, or rearrange, depending on temperature and environment.
In addition, the compound may have certain biological activity and may have potential uses in the fields of medicine and pesticides, but its specific activity remains to be further explored.
3 - pyridinecarboxylic Acid, 1, 2 - dihydro - 5 - iodo - 2 - oxo - what is the synthesis method
To prepare 3-pyridinecarboxylic acid, 1,2-dihydro-5-iodine-2-oxo, follow the following ancient method.
First take pyridine as the base, and introduce iodine atoms at the 5th position through a specific halogenation method. This halogenation method selects suitable halogenating reagents, such as iodine in combination with an appropriate oxidizing agent, in a specific reaction environment, control its temperature and duration, so that iodine atoms are precisely added to the 5th position of the pyridine ring to obtain 5-iodine pyridine.
Then, 5-iodine pyridine is oxidized to form a 2-oxo structure. Select an appropriate oxidizing agent, such as a reagent with suitable oxidation ability, in a suitable solvent system, adjust the reaction conditions, so that the pyridine ring forms a double bond between the 1,2 positions, and the 2 positions are oxidized to a carbonyl group to obtain 1,2-dihydro-5-iodine-2-oxo pyridine. After
, carboxylation of 1,2-dihydro-5-iodine-2-oxo pyridine is performed. A specific reaction path can be used, such as using a suitable reagent to interact with the substrate, in a suitable reaction vessel, under temperature control, pressure and other conditions, the pyridine ring is introduced into the carboxyl group at the 3rd position, and the final product is 3-pyridinecarboxylic acid, 1,2-dihydro-5-iodine-2-oxo-target product.
The whole reaction process requires careful monitoring of each step, and the reaction progress and product purity are determined by analytical methods, such as chromatography, spectroscopy, etc. And the control of the reaction conditions at each step is crucial to the yield and purity of the product.
3 - pyridinecarboxylic Acid, 1,2 - dihydro - 5 - iodo - 2 - oxo - what is the price range in the market
I think what you are asking about 3 + -pyridinecarboxylic acid, 1,2-dihydro-5-iodine-2-oxo is in the market price range. However, when this product is in the market, its price often changes due to various reasons, and it is difficult to say exactly.
Bearing the brunt, the price of raw materials has a great impact. If the price of all raw materials required for its preparation rises and falls, the price of this product will also change accordingly. If the starting material for preparing this pyridinecarboxylic acid derivative, if the output increases or decreases, the origin changes, and the supply and demand imbalance, the price will rise or fall, and it will be transmitted to the final product.
Furthermore, the simplicity of the preparation process is also the key. If the preparation requires complex and delicate steps, multiple reactions, purification, and a huge cost of manpower, material resources, and time, the cost will be high and the price will be high. On the contrary, if the process is simple and mature, the cost is controllable, and the price may be slightly lower.
The state of market supply and demand also affects its price. If the market demand for this product is strong and the supply is limited, merchants may raise the price to obtain a big profit; if the supply exceeds the demand, merchants will sell inventory or reduce the price for promotion.
In addition, factors such as the manufacturer's brand and product purity also play a role. Well-known manufacturers and high-purity products may have higher prices than ordinary ones.
Roughly speaking, this 3 + -pyridinecarboxylic acid, 1,2-dihydro-5-iodine-2-oxo substitute, at the market price or in the range of tens to hundreds of yuan per gram. However, this is only a rough estimate. The actual price needs to be consulted with the relevant chemical raw material suppliers in detail, and the exact quotation can be obtained according to the specific specifications and quantities.