3 Trifluoromethyl 4 Iodonitrobenzene
Iodobenzene

3 Trifluoromethyl 4 Iodonitrobenzene

Fengxi Chemical

Specifications

HS Code

430342

Chemical Formula C7H3F3INO2
Molar Mass 329.004 g/mol
Appearance Solid (usually)
Physical State At Room Temperature Solid
Melting Point Data may vary, typical range needs further literature search
Boiling Point Data may vary, typical range needs further literature search
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane
Density Data may vary, typical range needs further literature search
Flash Point Data may vary, typical range needs further literature search
Vapor Pressure Low vapor pressure
Stability Stable under normal conditions, but may react with strong oxidizing agents
Chemical Formula C7H3F3IN2O2
Molecular Weight 329.91
Appearance Solid (usually a yellow - colored solid)
Boiling Point Estimated high due to aromatic and polar groups
Melting Point Data may vary, but typically in a range characteristic of aromatic nitro - containing compounds
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Solubility In Water Insoluble in water due to non - polar fluoromethyl and aromatic groups
Density Calculated based on its molecular structure and expected to be relatively high
Reactivity Reactive at the iodine and nitro positions, can undergo substitution reactions
Stability Stable under normal conditions but may decompose on heating or in the presence of strong reducing or oxidizing agents
Chemical Formula C7H3F3INO2
Molar Mass 329.004 g/mol
Appearance Solid (likely yellowish, but color can vary)
Melting Point Data may vary, needs experimental determination
Boiling Point Data may vary, needs experimental determination
Density Data may vary, needs experimental determination
Solubility In Water Insoluble (due to non - polar nature of aromatic and fluoromethyl groups)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Stability Stable under normal conditions, but may react with strong reducing or oxidizing agents
Hazard Irritant to eyes, skin and respiratory system; may be toxic if swallowed or inhaled
Chemical Formula C7H3F3IN2O2
Molar Mass 329.91 g/mol
Appearance Solid (usually a powder)
Physical State At Room Temperature Solid
Solubility In Water Low solubility
Solubility In Organic Solvents Soluble in some organic solvents like dichloromethane
Melting Point Typically in a specific range (data may vary, around 90 - 100 °C)
Boiling Point Higher boiling point due to molecular weight and polarity
Odor Typically has an organic, pungent odor
Reactivity Reactive towards nucleophilic substitution reactions due to the presence of iodine and nitro group
Hazard Class May be classified as a hazardous chemical due to toxicity and flammability potential
Packing & Storage
Packing 100g of 3-(trifluoromethyl)-4-iodonitrobenzene packaged in a sealed glass bottle.
Storage Store 3-(trifluoromethyl)-4-iodonitrobenzene in a cool, dry, well - ventilated area away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent moisture and air exposure. Since it's a chemical, store it separately from incompatible substances like oxidizing agents, reducing agents, and bases to avoid potential reactions.
Shipping 3-(Trifluoromethyl)-4-iodonitrobenzene is shipped in sealed, corrosion - resistant containers. Compliance with strict hazardous chemical shipping regulations ensures safe transport, with proper labeling and handling to prevent spills and exposure.
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3-(trifluoromethyl)-4-iodonitrobenzene 3-(trifluoromethyl)-4-iodonitrobenzene 3-(trifluoromethyl)-4-iodonitrobenzene
General Information
Frequently Asked Questions
What is the main use of 3- (trifluoromethyl) -4-iodonitrobenzene?
Tris (Sanxiang methyl) -4-thiazolylfuran, its main use is to cover all things. According to Guanfu's "Tiangong Kaiwu", such things have their uses in various industries.
In the way of medicine, it can be the foundation of pharmaceuticals. Because of its unique structure and certain pharmacological activity, it can help doctors make all kinds of good medicines to treat people's diseases. For example, it can participate in the synthesis of specific drugs for certain diseases, so that patients can heal.
In the field of chemical industry, it is also indispensable. It can be a raw material for the synthesis of many chemical materials. With its characteristics, it can make materials with unique properties, either very tough or with good chemical stability, for the needs of construction, equipment and other industries.
In addition, in agriculture, it also has its function. Or it can be used as a component of pesticides to repel pests and protect the growth of crops. It allows farmers to maintain a good harvest and enrich the warehouse.
And it is in the process of scientific research, the key to exploring the unknown. Scientists rely on it to study new things, discover novelty, expand the frontier of human cognition, and pave the way for the progress of various disciplines.
In short, tris (Sanxiang methyl) -4-thiazolylfuran is widely used and plays an important role in many fields such as medicine, chemical industry, agriculture, scientific research, etc. It is an indispensable substance for the prosperity of people's livelihood, the prosperity of the industry, and the progress of academia.
What are the synthesis methods of 3- (trifluoromethyl) -4-iodonitrobenzene?
The synthesis of triethyl-4-pyridyl benzyl ether has various pathways, which are described in detail below.
First, it can be achieved by nucleophilic substitution reaction. Take appropriate halogenated benzyl, such as bromobenzyl or chlorobenzyl, and interact with triethyl-4-pyridyl alcohol salt. In a suitable solvent, such as dimethylformamide (DMF) or dimethyl sulfoxide (DMSO), under the catalysis of alkali, the halogen atom of halogenated benzyl can be attacked by the oxygen anion of triethyl-4-pyridyl alcohol salt nucleophilic, and then form a carbon-oxygen bond to obtain the target product triethyl-4-pyridyl benzyl ether. In this process, the choice of base is very critical. Potassium carbonate, sodium carbonate, etc. are commonly used, which can promote the formation of alkoxides and increase the reaction rate.
Second, with the help of Williamson synthesis method. First, triethyl-4-pyridyl alcohol is reacted with the base to generate the corresponding alkoxide, and then reacted with halogenated hydrocarbons. The halogenated hydrocarbons need to be benzyl halide, and the reaction conditions are mild. Under heating or room temperature, in a suitable solvent, nucleophilic substitution can occur smoothly to generate the desired ether.
Furthermore, the coupling reaction catalyzed by transition metals can be used. Using transition metals such as palladium and copper as catalysts, triethyl-4-pyridyl alcohol derivatives are coupled with benzyl halides in the presence of ligands and bases. This method has high selectivity and can effectively avoid side reactions, especially for synthesis that requires strict reaction conditions.
In addition, considering the activity of raw materials and reaction conditions, the synthesis efficiency and yield of triethyl-4-pyridyl benzyl ether can also be improved by improving the reaction solvent, adjusting the ratio of reactants, and optimizing the reaction temperature and time. And different synthesis methods have their own advantages and disadvantages. It is necessary to carefully choose the appropriate synthesis path according to the actual situation, such as the availability of raw materials, the difficulty of reaction, and the purity requirements of the product.
What are the physical properties of 3- (trifluoromethyl) -4-iodonitrobenzene?
Triethyl-4-azido phenyl sulfone is an important compound in organic synthesis. Its physical properties are as follows:
Looking at its appearance, under room temperature and pressure, triethyl-4-azido phenyl sulfone is mostly white to light yellow crystalline powder. This color and shape are conducive to researchers' preliminary identification during operation and observation.
When it comes to the melting point, the melting point of the compound is in a specific range. Precise control of the melting point is of great significance in the purification and identification of the compound. By measuring the melting point, its purity can be judged. If the purity is high, the melting point range is relatively narrow and close to the theoretical value; if it contains impurities, the melting point will be reduced and the melting range will be wider.
Solubility is also one of the key physical properties. Triethyl-4-azido benzene sulfone exhibits some solubility in common organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc. In dichloromethane, with its good solubility, it can be easily dissolved and used in organic synthesis reactions, providing a homogeneous reaction environment for various reactions. However, in water, its solubility is poor, which makes it necessary to pay special attention to its dispersion and reaction when it comes to reactions or operations in the aqueous phase.
In addition, the stability of triethyl-4-azido benzene sulfone cannot be ignored. The presence of azido groups makes the compound active to a certain extent. When heated, hit or come into contact with specific substances, it may cause decomposition or other chemical reactions. Therefore, during storage and use, strict specifications should be followed. Store in a cool, dry and well-ventilated place to avoid contact with incompatible substances to prevent danger.
What are the chemical properties of 3- (trifluoromethyl) -4-iodonitrobenzene?
The chemical properties of tris (trialkyl) -4-pyridylbenzene are as follows:
This compound exhibits a series of chemical properties due to its unique molecular structure. Judging from the pyridyl group and benzene ring contained in its structure, the nitrogen atom in the pyridyl group has a certain alkalinity and can react with acids to form corresponding salt compounds. Under appropriate conditions, the nitrogen atom on the pyridyl ring can be used as a nucleophilic check point to participate in nucleophilic substitution reactions.
The benzene ring part reflects the typical properties of aromatics. It has high stability and can undergo electrophilic substitution reactions, such as halogenation reactions. Under the catalysis of iron or iron salts, it can react with halogen elements, and the hydrogen atoms on the benzene ring are replaced by halogen atoms; in nitrification reactions, nitro groups are introduced into the benzene ring under the mixed acid of concentrated sulfuric acid and concentrated nitric acid; in sulfonation reactions, sulfonic acid groups can be introduced by co-heating with concentrated sulfuric acid. Although the chemical properties of the alkyl group in the
molecule are relatively stable, the hydrogen atoms on the alkyl group can undergo free radical substitution reactions under high temperature, light or the presence of initiators. Moreover, due to the power supply effect of alkyl groups, the electron cloud density distribution of the benzene ring and the pyridine ring will be affected, thereby changing their activity and selectivity for chemical reactions.
In addition, there may be interactions between the parts of the compound, which affect the overall chemical properties. For example, the electron cloud distribution between the pyridyl group and the benzene ring is affected by the conjugation effect, which affects the activity of the compound in various reactions and the selectivity of the reaction check point. These chemical properties make tri (trialkyl) -4-pyridylbenzene have potential applications in many fields such as organic synthesis and medicinal chemistry.
What are the precautions for 3- (trifluoromethyl) -4-iodonitrobenzene in storage and transportation?
Trimethyltetrabromophenol needs to be kept in mind when it is in storage.
The first word is that both need to be stored in a good, dry and clear place. Trimethylmethyl is easy to be stored, and high or humid conditions can easily cause its rate to accelerate, and even lead to leakage. Tetrabromophenol is stable, but the tide may also make it absorb moisture, affecting its chemical properties. Therefore, it must be kept dry and cool, and the temperature should be maintained at the appropriate temperature, generally at 5 to 30 degrees Celsius.
Furthermore, the two should be stored separately for oxidation, raw materials and other incompatible substances. Tetrabromophenol has a certain degree of originality. If it is oxidized together, a little carelessness may cause the original reaction of strong oxidation, forming a fire or explosion. Tetrabromophenol also partially reacts to the original reaction, changing its type and reducing its use efficiency.
It is necessary to use a sealed and corrosion-resistant container to prevent leakage. Tetrabromophenol should be packaged with moisture-proof and anti-corrosion materials to avoid collision and package damage on the way, and it should also have phase communication, fire protection and explosion-proof application. People are also well-versed in the dangerous characteristics and emergency management measures of the two, and will conduct regular inspections on the way. If there is any leakage, it will be properly handled immediately according to the case to ensure safety.