4 4 Hydroxy 3 Iodophenoxy 3 5 Diiodophenyl Acetic Acid
Iodobenzene

[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic Acid

Fengxi Chemical

Specifications

HS Code

796742

Chemical Formula C14H9I3O4
Molecular Weight 570.93
Iupac Name 2-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic acid
Appearance Solid (usually white to off - white)
Solubility In Water Poorly soluble
Solubility In Organic Solvents Soluble in some organic solvents like DMSO
Pka Value Around 4 - 5 (carboxylic acid group)
Boiling Point Decomposes before boiling
Melting Point Typically in the range of 180 - 190°C
Density Calculated density, approximate value around 2.5 - 2.7 g/cm³
Chemical Formula C14H9I3O4
Molecular Weight 575.93
Appearance Solid (usually white or off - white)
Odor Odorless (usually)
Solubility In Water Poorly soluble
Solubility In Organic Solvents Soluble in some organic solvents like ethanol, DMSO
Melting Point Specific value would require literature search
Boiling Point Decomposes before boiling (expected, due to its structure)
Pka Value related to the carboxylic acid group, specific value from literature
Stability Stable under normal conditions, but may decompose on exposure to strong oxidizing agents
Chemical Formula C14H9I3O4
Molecular Weight 571.93
Appearance Solid (presumed, based on common nature of such organic acids)
Solubility In Water Low (due to hydrophobic nature of aromatic rings)
Solubility In Organic Solvents Soluble in polar organic solvents like ethanol
Pka Around 4 - 5 (typical for carboxylic acids)
Boiling Point Decomposes before boiling (due to instability at high temperatures)
Odor Odorless or faint odor (common for many aromatic organic acids)
Reactivity Reactive towards bases (due to carboxylic acid group), can form esters with alcohols
Chemical Formula C14H9I3O4
Molar Mass 652.93 g/mol
Appearance Solid (usually white or off - white powder)
Solubility In Water Poorly soluble in water
Solubility In Organic Solvents Soluble in some organic solvents like DMSO, ethanol to some extent
Melting Point Typically in a certain range (data may vary, e.g., around 170 - 180°C)
Pka Value related to its acidic nature (data may vary, e.g., around 4 - 5 for the carboxylic acid group)
Density Estimated density based on related compounds (approximate value, e.g., around 2 - 3 g/cm³)
Stability Stable under normal storage conditions away from strong oxidizing agents and extreme heat
Packing & Storage
Packing 100g of [4-(4 - hydroxy - 3 - iodophenoxy)-3,5 - diiodophenyl]acetic acid in sealed chemical - grade packaging.
Storage [4-(4 - hydroxy - 3 - iodophenoxy)-3,5 - diiodophenyl]acetic Acid should be stored in a cool, dry place away from direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and contact with air, which could potentially lead to chemical degradation. Store it separately from incompatible substances to avoid reactions.
Shipping [4-(4 - hydroxy - 3 - iodophenoxy)-3,5 - diiodophenyl]acetic Acid is shipped in sealed, corrosion - resistant containers. Special handling precautions are taken due to its chemical nature to ensure safe transit and prevent any leakage.
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[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic Acid [4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic Acid [4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]acetic Acid
General Information
Frequently Asked Questions
What is the chemical structure of [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] acetic Acid?
The chemical structure of [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] acetic acid is a specific molecular structure in organic chemistry. The core of this compound is a phenyl group, on which many substituents are derived.
Looking at its structure, first above the benzene ring, there is a (4-hydroxy-3-iodophenoxy) group at position 4. This (4-hydroxy-3-iodophenoxy) group contains another benzene ring, which has a hydroxyl group at position 4 and an iodine atom at position 3, and is connected to the main benzene ring through an oxygen atom.
Furthermore, the 3-position and 5-position of the main benzene ring are each connected with an iodine atom. And at the 1-position of the main benzene ring, there is an acetic acid group, that is, -CH ³ COOH structure.
From this, it can be seen that the chemical structure of [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] acetic acid, with the benzene ring as the skeleton, is connected by substituents at different positions to form this specific organic compound structure. Each group interacts to endow the compound with specific chemical properties and reactivity.
What are the main uses of [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] acetic Acid?
[4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] acetic acid, an organic compound. Its use is quite extensive, in the field of medicine, or can be used to create new drugs. Because its structure is rich in iodine atoms and specific phenoxy and carboxyl structures, or it has unique biological activities, it may have potential efficacy in the treatment of certain diseases, or it can participate in the synthesis of pharmaceutical chemistry, providing key intermediates for the development of targeted therapeutic drugs.
In the field of materials science, or because of its special molecular structure, it can be appropriately modified and processed to prepare materials with special properties. For example, with the help of its intermolecular interactions and reactivity, polymer materials with specific functions can be synthesized, or used to develop materials with recognition and adsorption properties for specific substances.
In addition, in the field of organic synthetic chemistry, as an important class of organic intermediates, it can provide starting materials or key modules for the construction of more complex organic molecular structures. Chemists can use its activity check point to achieve precise regulation and construction of molecular structures through various organic reactions, such as nucleophilic substitution, coupling reactions, etc., to prepare organic compounds with specific functions and structures.
What are the physical properties of [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] acetic Acid?
[4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] acetic acid, its physical properties are particularly important, and it is related to the characteristics and applications of this compound.
Looking at this compound, under normal temperature and pressure, it is mostly in the shape of a solid state. This is due to the relatively strong intermolecular force, which allows it to maintain a solid state in general environments. Its color is often white or off-white, and the color is more uniform when it is pure.
As for the melting point, it has been determined by many experiments that it is within a specific temperature range. This temperature limit varies depending on the purity of the compound and the experimental conditions. When heated to near the melting point, the molecule is energized, the lattice structure gradually disintegrates, and then it melts from a solid state to a liquid state.
In terms of solubility, this compound has a certain solubility in organic solvents such as ethanol and acetone. Due to the fact that the molecules of the organic solvent can form suitable interactions with the molecules of the compound, such as van der Waals force, hydrogen bond, etc., to help it disperse in the solvent medium. However, in water, its solubility is not good. This is because the hydrophobic groups in the molecular structure account for a large proportion, and it is difficult to form effective interactions with water molecules, making it difficult to dissolve in water.
Its density is also an inherent physical property, which characterizes the mass of the substance per unit volume. This value reflects the degree of tight packing of molecules, and is of great significance for the study of its behavior in different systems, such as sedimentation and mixing in solution.
The physical properties of this compound, such as morphology, color, melting point, solubility, density, etc., play an important role in chemical synthesis, drug development, materials science and other fields, laying the foundation for its rational application and in-depth research.
What are the synthesis methods of [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] acetic Acid?
The synthesis method of [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] acetic acid has been explored by chemists since ancient times and now. There are many methods, each with its own strengths. The following are selected from the main ones, and the ancient Chinese say.
First, halogenated benzene is used as the beginning, and the method of phenylation makes the halogen atom replaced by the hydroxyl group, so that the hydroxyl-containing benzene is obtained. Then, iodine is replaced by iodine, and the iodine atom is introduced at a specific position in the benzene ring to obtain the iodine-containing benzene derivative. Then, by etherification, the hydroxyl-containing benzene is connected to another halogenated benzene to form an ether bond structure. After carboxylation, a carboxyl group is added at a specific position to obtain the target product.
Second, benzene containing phenolic hydroxyl groups is used as the starting material. First, iodine atoms are introduced into the benzene ring with iodine substitution reagent according to specific reaction conditions to obtain intermediates with iodine and phenolic hydroxyl groups. Then, by nucleophilic substitution, phenolic hydroxyl groups are formed with halogenated phenyl ethers to construct ether bonds. Finally, through a specific carboxylation reaction, carboxyl groups are introduced at suitable check points to complete the synthesis of the target product.
Third, phenyl ring compounds with specific substituents are selected, and with the help of organometallic reagents, halogen-metal exchange reactions are carried out to generate active metal-organic intermediates. Then react with iodine-containing electrophilic reagents to introduce iodine atoms. After a series of reactions, including ether bond formation, carboxyl group introduction and other steps, this [4- (4-hydroxy-3-iodophenoxy) -3,5 -diiodophenyl] acetic acid can also be obtained.
The synthesis methods depend on the availability of raw materials, the difficulty of reaction, and the high and low yield. However, fine operation and strict control of the reaction conditions are required to obtain pure products for subsequent research and application.
What are the precautions for [4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] acetic Acid during use?
[4- (4-hydroxy-3-iodophenoxy) -3,5-diiodophenyl] acetic acid. When using this product, many matters must be paid attention to.
First, it is safe, and its nature may be unknown. During operation, protective equipment, such as gloves, goggles, etc., must be worn to prevent contact with skin and eyes, causing injury to the body. If you accidentally touch it, rinse it with plenty of water quickly, and in serious cases, seek medical attention urgently.
Furthermore, it is related to storage. It needs to be placed in a dry, cool and ventilated place, away from fire and heat sources. Because of its sensitivity to heat and light, improper environment, or deterioration, it loses its effectiveness, and even causes dangerous changes.
The use environment is also important. When used in a well-ventilated place, if in a closed place, its volatile substances may cause air pollution and endanger people. And do not approach acids and alkalis and other substances to prevent chemical reactions and cause disasters.
Weighing and dosage also need to be accurate. According to the needs of experiment or production, measure carefully, not more or less. Too much is wasteful, and may cause adverse reactions; too little is not the expected effect.
Operation steps must be followed according to the specifications. Know the relevant process in advance, follow it step by step, and do not change it at will. Every step is related to success or failure and safety. If there is a slight mistake, it is easy to make mistakes.
At the end of the day, after use, properly dispose of the remaining materials and waste. Do not discard at will, and dispose of it according to the prescribed law, so as not to pollute the environment and cause harm to all parties. In this way, the use process will be smooth and safe, and the intended purpose will be achieved.