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4- (4-hydroxy-3-iodophenyl) What are the chemical properties of benzonitrile?
4- (4-hydroxy-3-iodophenyl) benzonitrile is an organic compound. Its chemical properties are unique, including nitrile (-CN) and hydroxyl (-OH), and iodine atoms attached to the benzene ring.
The nitrile group is active in nature and can be converted into carboxyl (-COOH) by hydrolysis reaction, or amino (-NH2O) by reduction reaction. Hydroxy groups have the characteristics of typical alcohols and can participate in esterification reactions and interact with acids to form ester compounds; they can also undergo substitution reactions, and the hydroxyl groups are replaced by other functional groups. The iodine atom on the
benzene ring affects the electron cloud distribution of the benzene ring due to its electronegativity, which in turn affects the reactivity and selectivity of the compound. In the nucleophilic substitution reaction, the iodine atom can be used as a leaving group and replaced by other nucleophilic reagents.
This compound can participate in many organic synthesis reactions because it contains a variety of functional groups, and is used to construct more complex organic molecules. It has potential application value in the fields of medicinal chemistry, materials science and so on. Its physical properties or specific melting boiling point and solubility due to the existence of functional groups need to be carefully considered in practical applications and experimental operations.
4- (4-hydroxy-3-iodophenyl) What are the main uses of benzonitrile?
4- (4-hydroxy-3-iodophenyl) benzonitrile, this substance is used in today's chemical industry and has a wide range of uses.
First, in the field of pharmaceutical creation, this compound has potential value. Because iodine and hydroxyl, nitrile and other groups can interact with specific targets in the body. Chemists use its unique structure to explore its therapeutic effect on diseases. For example, when developing anti-cancer drugs, it may be able to target tumor cells, interfere with their metabolism or proliferation process, and achieve the purpose of inhibiting tumor growth.
Second, in the field of materials science, it can also be used. Because of its special chemical structure, or endow materials with unique electrical and optical properties. It can be used to prepare organic optoelectronic materials, such as organic Light Emitting Diode (OLED). In the manufacture of OLED, its structure may improve the luminous efficiency and stability of the material, make the display screen clearer and energy-saving, and be used in display devices such as mobile phones and TVs.
Third, it may be able to show its skills in the development of pesticides. Its chemical group combination may inhibit or kill some pests and pathogens. It can be modified and optimized to develop high-efficiency and low-toxicity pesticides to escort agricultural production, reduce the damage of pests and diseases to crops, and improve yield and quality.
In conclusion, 4- (4-hydroxy-3-iodophenyl) benzonitrile has potential uses in many fields such as medicine, materials, and pesticides. With the deepening of scientific research, more novel applications may be discovered.
4- (4-hydroxy-3-iodophenyl) What are the synthesis methods of benzonitrile?
There are many methods for synthesizing 4- (4-hydroxy-3-iodophenyl) benzonitrile in the past. One method is to introduce iodine atoms at specific positions in the benzene ring by halogenation from suitable starting materials. First, the compound containing the benzene ring is taken and carefully designed to react with the iodine source under specific conditions, such as in a suitable catalyst and solvent system, so that the iodine atom precisely falls in the 3-position to form the 3-iodine intermediate.
Then, by the hydroxylation reaction, the hydroxyl group is introduced at the 4-position. This step requires the selection of suitable hydroxylation reagents and reaction conditions, so that the reaction can be carried out efficiently and in a directional manner to obtain 4-hydroxy-3-iodobenzene derivatives.
Then nitrile reaction, the benzyl group is partially converted into a nitrile group. In this process, the selection of appropriate nitrile reagents and reaction conditions is crucial, so that the benzyl group can be chemically converted into the target nitrile group, thereby constructing the structure of 4- (4-hydroxy-3-iodophenyl) benzonitrile.
Another way of synthesis may be to start from different starting materials, first construct a benzene ring skeleton containing nitrile groups, and then introduce iodine atoms and hydroxyl groups at specific positions through selective halogenation and hydroxylation reactions, in order to achieve the purpose of synthesizing the target product. During synthesis, the precise control of the reaction conditions and the fine selection of reagents are all related to the success or failure of the reaction and the purity of the product, and caution is required.
4- (4-hydroxy-3-iodophenyl) What are the precautions during storage and transportation of benzonitrile?
4- (4-hydroxy-3-iodophenyl) benzonitrile is also an organic compound. During storage and transportation, all precautions should not be ignored.
Bear the brunt, storage is important, care about the environment. It should be placed in a cool, dry and well-ventilated place. This is because the compound may be afraid of heat and moisture. If it is in a high temperature place, it may cause its chemical properties to change, or even cause disasters such as decomposition; if it is in a humid environment, it may cause moisture to dissolve and damage its quality.
Furthermore, keep away from fire and heat sources. Because of its flammability, in case of open flames and hot topics, it is easy to cause the risk of combustion and endanger the safety of the surroundings.
When storing, it should also be stored in isolation from oxidants, acids, alkalis, etc. Due to its chemical activity, coexistence with them can easily trigger chemical reactions, or cause explosions or produce harmful substances.
As for the transportation, the packaging must be tight. Make sure it is not damaged and leaked due to vibration or impact. The transportation vehicle should also be selected as safe and reliable, and equipped with corresponding fire protection equipment to avoid danger.
The person escorting the transportation must be familiar with the characteristics of the compound and the emergency response method. In case of leakage, we can take appropriate measures and deal with it quickly to reduce the harm.
In general, the storage and transportation of 4- (4-hydroxy-3-iodophenyl) benzonitrile should be strictly adhered to and handled carefully to ensure its safety and avoid disasters.
4- (4-hydroxy-3-iodophenyl) What is the environmental impact of benzonitrile?
4 - (4-hydroxy-3-iodophenyl) benzonitrile, the impact of this substance on the environment is particularly complex and involves many factors.
First of all, from the perspective of its chemical structure, it contains functional groups such as iodine and cyanyl. Iodine is in the environment or participates in various biogeochemical cycles. However, in this compound, due to chemical bonds binding, its behavior may be different from elemental iodine. If this substance is released into nature, through weathering, hydrolysis and other processes, iodine may be detached, affecting the local iodine cycle and affecting the balance of iodine in aquatic and terrestrial ecosystems. Although iodine is an essential trace element for life, excess or biological metabolic disorders. Taking aquatic organisms as an example, it may affect their thyroxine synthesis, causing growth and reproduction to be hindered.
Furthermore, the cyanyl group is highly toxic. If 4- (4-hydroxy-3-iodophenyl) benzonitrile degrades in the environment, the cyanyl group is free, which is very harmful to surrounding organisms. Cyanide can inhibit cellular respiration enzymes, causing biological cells to be unable to uptake oxygen normally, and acute poisoning can cause rapid death of organisms. In the soil environment, it may affect the structure and function of microbial communities, destroy the ecological balance of the soil, and hinder the decomposition of organic matter and nutrient circulation.
In addition, the existence of 4-hydroxy groups may make the compound have a certain hydrophilicity, which affects its migration in environmental media. It may be soluble in water and diffuse with runoff, expanding the scope of pollution. Compounds with hydroxyl groups may participate in complex photochemical reactions under light, heat and other conditions to generate new pollutants, increasing the complexity of environmental hazards.
In summary, the impact of 4- (4-hydroxy-3-iodophenyl) benzonitrile on the environment covers many aspects such as element cycle, biotoxicity and migration and transformation. Careful study is needed to clarify its latent risk and provide a solid basis for environmental protection and pollution prevention and control.