4 Amino 1 2 Deoxy 2 Fluoropentofuranosyl 5 Iodopyrimidin 2 1h One

This is the name of 4-amino-1- (2-deoxy-2-fluoropentanofuran glycosyl) -5-iodopyrimidine-2 (1H) -one. Looking at its name, its chemical structure can be deduced. This compound contains a pyrimidine ring, with a ketone group at the 2nd position, an amino group at the 4th position, and an iodine atom at the 5th position. And it is connected to a pentanofuran glycosyl group at the 1st position, which is deoxidized at the 2nd position and has a fluorine atom substitution.
The analysis of its structure should start from the pyrimidine ring. Pyrimidine is a six-membered nitrogen-containing heterocycle with a specific electron cloud distribution and chemical activity. The 2-position ketone group on the ring affects the electron cloud density and chemical reactivity of the molecule, and is easy to participate in nucleophilic addition and other reactions. The 4-position amino group is alkaline, which can form salts with acids, and can also participate in nucleophilic substitution and other reactions. The 5-position iodine atom has a large atomic radius and electronegativity, which can make the molecule have unique physical and chemical properties.
Then look at the pentofuran sugar group connected to it. The pentofuran sugar group contains five carbon atoms and has a furan ring structure. The 2-position deoxygenation makes the sugar group structure different from that of ordinary pentose, while the 2-position fluorine atom is substituted. Because the fluorine atom has a large electronegativity, it significantly affects the distribution and spatial structure of the sugar group electron cloud,
In summary, the chemical structure derived from this name is composed of a pyrimidine ring connected to a specific modified pentafuran sugar group, and each substituent gives the molecule unique physical and chemical properties, which lays the foundation for the study of chemical reactions and biological activities.

4 - amino - 1 - (2 - deoxy - 2 - fluoropentofuranosyl) -5 - iodopyrimidin - 2 (1H) -one, this is the name of a compound. Its main uses are quite extensive, in the field of medicinal chemistry, it is mostly used in the research and development of antiviral drugs. Due to its unique structure, it can effectively inhibit the replication process of viruses.
Watching the virus wreak havoc, eroding the human body, like a foreign enemy invasion, disrupting the normal physiological order. And this compound, like a warrior, with its special structure, can accurately act on the key link of virus replication, just like setting a checkpoint in the key of the enemy army, hindering the reproduction of the virus, so as to achieve the purpose of anti-virus.
In the development of anti-tumor drugs, it also has its own role. Abnormal proliferation of tumor cells endangers life. This compound can affect the metabolism and proliferation pathways of tumor cells, just like putting shackles on the crazy growth of tumor cells, restricting their wanton spread. By interfering with key metabolic processes of tumor cells, such as nucleic acid synthesis, and then inhibiting the growth and spread of tumor cells, it provides new opportunities and hope for anti-tumor treatment.
Furthermore, in the field of biochemical research, it is also an important tool. Scientists can gain insight into the mysteries of life processes by studying the interaction of this compound with biological macromolecules. It is like providing a beacon for exploring the labyrinth of life, helping researchers gain a deeper understanding of the structure and function of nucleic acids, and contributing to the development of life science, so that we can have a deeper understanding and understanding of the essence of life.

The method of preparing 4 - amino - 1 - (2 - deoxy - 2 - fluoropentofuranosyl) -5 - iodopyrimidin - 2 (1H) -one is the category of organic synthetic chemistry, and the process is quite delicate.
The choice of starting materials is very important. Usually start with pyrimidine compounds and glycosylation reagents containing suitable substituents. For example, choose a pyrimidine derivative, which has 2 positions that can be converted to carbonyl groups, 5 positions for introducing iodine atoms, and 4 positions for amination check point. The glycosylation reagent needs to have the structure of 2-deoxy-2-fluoropentafuran.
The first step, or the glycosylation reaction. Here, the pyrimidine derivative and the glycosylation reagent are added to a suitable catalyst, usually Lewis acid, under suitable reaction conditions, such as in a specific organic solvent, to catalyze the connection of the glycosylation group to the nitrogen atom of the pyrimidine ring to construct the glycosylation intermediate. This reaction requires precise temperature control and time control to ensure the selectivity and yield of the reaction.
Then, 5 positions of the resulting intermediate are iodized. An iodizing reagent, such as a combination of iodine elemental substance and a suitable oxidizing agent, can be used in a suitable reaction system to selectively replace the specific group of 5 positions with an iodine atom to form an iodine-containing intermediate. This step also requires careful regulation of reaction parameters to prevent side reactions. At the end of
, amination is performed on the 4-position. Usually an ammonia source, such as an alcohol solution of ammonia gas, or a suitable amination reagent, under suitable reaction conditions, the 4-position is introduced into the amino group, and the final product is 4-amino-1- (2-deoxy-2-fluoropentofuranosyl) -5 -iodopyrimidin-2 (1H) -one. After the reaction is completed, separation and purification techniques, such as column chromatography, recrystallization, etc. are required to obtain a high-purity target product. The whole preparation process requires fine operation and strict control of reaction conditions to obtain satisfactory results.

4 - amino - 1 - (2 - deoxy - 2 - fluoropentofuranosyl) -5 - iodopyrimidin - 2 (1H) -one is an organic compound. It has several physical and chemical properties.
Looking at its physical properties, the properties of this compound under normal conditions depend on its molecular structure and composition, or it is solid. The intermolecular forces, hydrogen bonds and van der Waals forces interact to make the molecules arranged in an orderly manner, resulting in a solid state. As for the melting point, due to the presence of amino groups, halogens and other functional groups in the molecule, the interaction between them enhances the intermolecular binding force, so the melting point may be in a certain high range. However, the exact value still needs to be accurately determined by experiments.
When it comes to chemical properties, its amino group has a certain alkalinity and can react with acids to form corresponding salts. This is because the nitrogen atom in the amino group has a lone pair of electrons and can accept protons. The iodine atom in the molecule, although the carbon-iodine bond is relatively weak, endows the compound with certain reactivity. Under specific conditions, nucleophilic substitution reactions can occur, and iodine atoms can be replaced by other nucleophilic reagents. In addition, the presence of fluorine atoms in the 2-deoxy-2-fluoropentafuran glycosyl part changes the electron cloud distribution of glycosyl groups, affects the overall stability and reactivity of the compound, or makes the compound exhibit a unique reaction path and selectivity in some reactions involving glycosyl groups. Its pyrimidine ketone ring is also aromatic and can participate in some common reactions of aromatic compounds, such as electrophilic substitution reactions. Due to the characteristics of electron cloud density distribution on the ring, the reaction check point may have specific selectivity.

4 - amino - 1 - (2 - deoxy - 2 - fluoropentofuranosyl) - 5 - iodopyrimidin - 2 (1H) - one is a chemical substance, and its safety is related to many ends. Let me tell you in detail.
This substance may have specific effects in pharmacological research, but its safety is first involved in toxicity. Although there is no detailed ancient book to compare, in today's scientific view, chemical compounds need to be carefully tested for toxicity. If it enters the organism or interacts with intracellular molecules, it will damage the normal function of the cell. For example, it may interfere with DNA synthesis and repair, because the structure of pyrimidine is involved in nucleic acid metabolism. If so, it may cause genetic mutation, cause cell cancer or abnormal function, and pose a serious threat to the health of organisms.
Repeat its environmental safety. If this substance accidentally flows into the environment, in water, soil, or through diffusion, degradation and other processes. However, because of its fluoride, iodine and other elements, or affect the structure and function of microbial communities, it disrupts the material cycle and energy flow of the ecosystem. And its degradation products are also unknown, or have higher toxicity or durability, endangering environmental organisms.
Re-discuss its safety of use. In experimental operations or industrial production, if the operator is not properly protected, contact with this substance, or absorb it through the skin, respiratory inhalation. In light cases, it causes skin and respiratory irritation, and in severe cases, it damages internal organs. If long-term inhalation of dust or gas containing this substance, or cause lung diseases, affect respiratory function.
In summary, the safety of 4 - amino - 1 - (2 - deoxy - 2 - fluoropentofuranosyl) - 5 - iodopyrimidin - 2 (1H) - one needs to be explored in an all-round and multi-level way. Caution should be taken in all aspects of use and disposal to ensure biological safety and environmental health.