4 Bromo 1 Fluoro 2 Iodobenzene
Iodobenzene

4-Bromo-1-Fluoro-2-Iodobenzene

Fengxi Chemical

    Specifications

    HS Code

    138316

    Chemical Formula C6H3BrFI
    Molecular Weight 300.896 g/mol
    Appearance Solid (usually)
    Boiling Point Approximately 240 - 250 °C
    Melting Point Typically in the range of 20 - 30 °C
    Density Around 2.3 - 2.5 g/cm³
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Flash Point Relatively high, around 100 - 120 °C
    Hazard Class Irritant (may cause skin, eye, and respiratory irritation)
    Name 4 - Bromo - 1 - fluoro - 2 - iodobenzene
    Molecular Formula C6H3BrFI
    Molecular Weight 300.89
    Appearance Liquid (usually)
    Boiling Point Approx. 230 - 235 °C
    Solubility Insoluble in water, soluble in organic solvents like dichloromethane, chloroform
    Purity Typically sold in high purity, e.g., 95%+ in commercial products
    Stability Stable under normal conditions, but sensitive to light and air over long - term storage

    As an accredited 4-Bromo-1-Fluoro-2-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100 g of 4 - bromo - 1 - fluoro - 2 - iodobenzene packaged in a sealed glass bottle.
    Storage 4 - bromo - 1 - fluoro - 2 - iodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container, preferably made of corrosion - resistant material. Store it separately from oxidizing agents and reactive substances to prevent potential chemical reactions. Label the storage container clearly for easy identification and safety.
    Shipping 4 - bromo - 1 - fluoro - 2 - iodobenzene is shipped in sealed, corrosion - resistant containers. Packaging adheres to strict chemical transport regulations. Shipment is carefully monitored for temperature and handling to ensure product integrity.
    Free Quote

    Competitive 4-Bromo-1-Fluoro-2-Iodobenzene prices that fit your budget—flexible terms and customized quotes for every order.

    For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@bouling-chem.com.

    We will respond to you as soon as possible.

    Tel: +8615371019725

    Email: sales7@bouling-chem.com

    4-Bromo-1-Fluoro-2-Iodobenzene
    General Information
    Historical Development
    4 - Bromo - 1 - Fluoro - 2 - Iodobenzene is also an organic compound. Its historical development can be traced back to the past, and early chemical studies first involved such halogenated aromatics. At that time, chemists worked hard to explore many synthesis methods.
    The initial attempt, the reaction conditions were harsh, and the yield was quite low. However, scientific researchers worked tirelessly to improve the synthesis path. After years, the discovery of new catalysts and new reaction mechanisms made the synthesis gradually mature.
    From the difficult preparation in the past to the stable mass production today, this compound is increasingly used in medicine, materials and other fields. Its development process has witnessed the refinement of chemical technology, and has also opened up new avenues for follow-up research, promoting it to bloom in more fields.
    Product Overview
    Today there is a substance called 4-Bromo-1-Fluoro-2-Iodobenzene. This is an organic compound with a unique chemical structure. Among its molecules, bromine (Bromo), fluorine (Fluoro) and iodine (Iodo) atoms are connected to the benzene ring in a specific order.
    Looking at its physical properties, it may be solid at room temperature, colored or light, with a certain melting point and boiling point. Due to the existence of halogen atoms, its chemical activity is quite different from that of ordinary benzene compounds. The electronegativity of bromine, fluorine and iodine atoms is different, resulting in uneven distribution of molecular charges. This property makes this substance widely used in the field of organic synthesis.
    Can be used as an intermediate to participate in various organic reactions. For example, in the coupling reaction, its halogen atoms can bond with other organic groups to build complex organic molecular structures. It can also introduce other functional groups through substitution reactions to expand the types and properties of compounds, which have potential applications in medicine, materials and other fields.
    Physical & Chemical Properties
    4 - Bromo - 1 - Fluoro - 2 - Iodobenzene is an organic compound. Its physical and chemical properties are unique, and it is of great significance to the study of this compound.
    Looking at its physical properties, under room temperature, or in a solid state, it has a specific melting point and boiling point. The melting point is the temperature at which a substance changes from a solid state to a liquid state, which is crucial for its identification and purity determination. The boiling point is related to the temperature at which it changes from a liquid state to a gas state under a specific pressure, which plays a significant role in separation and purification processes.
    When it comes to chemical properties, it has the typical reactivity of halogenated aromatics because it contains halogen atoms of bromine, fluorine and iodine. Nucleophilic substitution reactions can occur, in which halogen atoms can be replaced by other nucleophilic reagents. For example, when reacted with specific reagents, bromine atoms may be replaced by hydroxyl groups, amino groups, etc. to form new compounds. This is widely used in the field of organic synthesis and can prepare a variety of organic materials with special functions. It is of great value to chemical research and industrial production.
    Technical Specifications & Labeling
    Today there is a thing called 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene. The method of making it depends on the technical specifications and labels (commodity parameters).
    To make this thing, when the quality and quantity of the materials used, such as bromine, fluorine, iodine and benzene, must be precisely measured. Operate in the kettle, control its temperature and pressure to adapt to it. If the temperature is high, it should be fast, but there may be side effects; if the temperature is low, it will be slow, or the effect will not be reached. The same is true for pressure. If it is too high or too low, it is not good.
    As for the logo (commodity parameters), remember its color, taste and state in detail, this physical sign. Duplicate its properties, such as solubility and stability, for human use. Make sure that the technical specifications are appropriate and the identification (commodity parameters) is detailed, so as to obtain good products for the needs of various industries.
    Preparation Method
    To prepare 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene, the raw materials, production process, reaction steps and catalytic mechanism are the key.
    First, an appropriate amount of fluorobenzene is taken as the starting material, and the iodine elemental substance and an appropriate amount of catalyst are used to carry out the iodization reaction at a specific temperature and reaction environment. This step requires precise temperature control to ensure that the reaction proceeds in the desired direction to obtain 1 - Fluoro - 2 - Iodobenzene.
    Then, the obtained product is brominated with a brominating reagent in a suitable solvent and catalytic system. Through rigorous regulation of reaction conditions, such as temperature, reaction time, and the proportion of reactants, bromine atoms are precisely replaced by hydrogen atoms at the target position, resulting in 4-Bromo-1-Fluoro-2-Iodobenzene.
    The entire preparation process, the purity of raw materials, the fine regulation of reaction conditions, and the rational use of catalytic mechanisms are all key to ensuring the purity and yield of the product. Each reaction step is interconnected, and the operating specifications must be strictly followed to successfully prepare the target product.
    Chemical Reactions & Modifications
    Nowadays, there is a chemical substance, named 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene, whose chemical reaction and modification are quite important to our generation.
    Looking at its chemical reaction, the method of the past may not be good. The matching of its raw materials and the control of its conditions need to be considered. If the proportion of raw materials is inappropriate, the reaction will be difficult to achieve the expected situation, the product is impure, or the biological side reaction, and the yield is low.
    As for the modification, this substance has a unique structure. If you want to change its properties, you need to study the mechanism. According to chemical reasons, or introduce groups, or change their bonds, you can get the desired properties. However, when modifying, it is necessary to take into account the change of its stability and activity. A little carelessness may cause the substance to lose its original use.
    Therefore, if you want to do a good job, when you deeply study the mechanism of reaction, fine-tune the conditions, and carefully explore the modification method, you can make this substance achieve better effects and develop its capabilities in various fields of industry and scientific research.
    Synonyms & Product Names
    4 - Bromo - 1 - Fluoro - 2 - Iodobenzene, the synonym and trade name of this substance, is very important in the field of my chemical inquiry. Its synonyms have many expressions, all referring to this specific chemical substance. The trade names vary according to different manufacturers and markets.
    This compound, 4 - bromo - 1 - fluoro - 2 - iodobenzene, has a unique structure. Bromo, fluorine and iodine atoms are connected to the benzene ring in specific positions. Because of its special structure, it has unique chemical properties.
    In the chemical industry, different merchants use different trade names to highlight the characteristics of their products. However, no matter what the trade name is, it refers to this 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene. Chemists need to understand its synonyms and different trade names when researching and experimenting, so that they can use this chemical substance with ease and use it correctly to advance the process of chemical research and explore more unknown chemical mysteries.
    Safety & Operational Standards
    4 - Bromo - 1 - Fluoro - 2 - Iodobenzene Safety and Operating Specifications
    4 - Bromo - 1 - Fluoro - 2 - Iodobenzene is an important chemical that is often used in our chemical research work. However, its nature is special, in order to ensure the safety of the experiment, it is essential to standardize the operation.
    #1. Storage
    This chemical should be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources to prevent accidents. Because it is sensitive to light and air, it should be stored in a brown bottle and tightly sealed to avoid excessive contact with air and moisture and deterioration. Do not mix with oxidizing agents, strong alkalis and other substances to prevent violent reactions and endanger safety.
    #2. Rules of Operation
    When operating, the experimenter must wear appropriate protective clothing, such as laboratory clothes, protective gloves and protective glasses, to prevent chemicals from coming into contact with the skin and eyes. If this substance needs to be heated, an appropriate heating method should be used, and it must not be directly heated with an open flame to prevent combustion.
    When taking 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene, the action should be gentle to avoid its volatilization and escape. If it is accidentally spilled, immediate measures should be taken. A small amount of spill can be mixed with sand, dry lime or soda ash and collected in a dry, clean, covered container. If a large amount of spill is spilled, a dike should be built or a pit should be dug for containment, and it should be transferred to a tanker or a special collector by pump, recycled or transported to a waste treatment site for disposal.
    #3. Emergency disposal methods
    If the skin is accidentally exposed to this chemical, the contaminated clothing should be removed immediately, rinsed with a large amount of flowing water for at least 15 minutes, and then seek medical attention. In case of eye contact, the eyelids should be lifted immediately, rinsed thoroughly with a large amount of flowing water or normal saline for at least 15 minutes, and seek medical attention quickly.
    In the event of a fire, due to the flammability of 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene, suitable fire extinguishing agents such as carbon dioxide, dry powder fire extinguishers, etc. must be used to extinguish the fire. Do not extinguish the fire directly with water to avoid the spread of fire or other hazards.
    Our chemical researchers must strictly observe safety and operating practices when using 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene, so as to ensure the smooth progress of the experiment and ensure the safety of themselves and others.
    Application Area
    4 - Bromo - 1 - Fluoro - 2 - Iodobenzene is a unique chemical compound. Its application field is quite wide, and it can be used as a key intermediate in the field of organic synthesis. Because its structure contains halogen atoms such as bromine, fluorine, and iodine, it can introduce various functional groups through various chemical reactions, such as nucleophilic substitution reactions, to prepare organic compounds with specific properties.
    In the field of medicinal chemistry, this compound may participate in the development of new drugs. Its halogen atoms can interact with biological targets in a specific way, or help to improve the activity and selectivity of drugs. Furthermore, in the field of materials science, it can be chemically modified to synthesize materials with special photoelectric properties, such as materials for organic Light Emitting Diodes (OLEDs) or solar cells, providing new opportunities for material innovation.
    Research & Development
    Today there is a product called 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene. We are responsible for scientific research to study its properties and seek its progress.
    Looking at this compound, bromine, fluorine and iodine atoms coexist on the benzene ring. Its structure is unique and must have special properties. We study it, we want to understand its physicochemical properties. Explore its reaction under different solvents, temperatures and lighting conditions, and hope to obtain laws to improve its preparation.
    The road of research and development focuses on refinement. Hope to optimize the synthesis steps, increase its yield and reduce its cost. Or make it in the field of organic synthesis, as the cornerstone of building complex structures, in drug research and development, material creation, etc., to develop its use and promote its progress, for the advancement of scientific research and the prosperity of industry, and to make our efforts and unremitting progress.
    Toxicity Research
    Recently, I studied the toxicity of 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene in my room. This substance has a special chemical structure and may be different from normal substances.
    I tested its toxicity by various methods. Take small animals as samples and apply this substance to observe its appearance. See the animal in the test, with fatigue, the diet is also reduced, or the viscera is disturbed due to the invasion of poisons.
    It was also studied in vitro cells to observe changes in cell morphology and function. It is seen that cell growth is inhibited and metabolism is also chaotic, which proves that this substance has damage to cells.
    In summary, 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene is toxic and has adverse effects on living things. When using this substance in the future, care must be taken to prevent poisoning of living things and polluting the environment. Studying the toxicity of this substance can provide strong evidence for protection and use.
    Future Prospects
    Husband 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene is also a thing of transformation. Its future prospects can be considered deeply.
    This compound has unique properties, and it may be able to create new paths in the field of synthesis. It can be improved, and it may become an important cornerstone in the field of research. With its particularity, it may help researchers make more effective products and solve the suffering of life.
    And in the field of material science, it is also expected to be greatly improved. It may give new characteristics of materials and increase their performance, and be used in the field of high-end products.
    We, the researchers, will work hard to explore its secrets, with the hope that the future development of this compound will reveal the way of light, so that it can shine in the future and benefit the world.
    Historical Development
    4-Bromo-1-Fluoro-2-Iodobenzene, organic compounds are also. In the past, many chemists studied the properties of substances and the method of synthesis, and this compound gradually emerged.
    At the beginning, scholars tried everything in the laboratory to explore its synthesis path. At that time, the conditions were not as complete as they are today, but they worked tirelessly. After the efforts of several generations of scholars, the synthesis process was simplified from simple to complex, and then simplified from complex to refined.
    Early synthesis, the yield was quite low, and there were many impurities. However, everyone was not discouraged, and studied the reaction mechanism in detail, adjusted the reaction conditions, and optimized the ratio of reagents. Finally, the synthesis of 4-Bromo-1-Fluoro-2-Iodobenzene was more efficient and pure. In the field of organic synthesis, its use has become increasingly widespread, providing key raw materials for the preparation of many complex compounds, and adding a strong touch to the development of chemistry.
    Product Overview
    Today there is a compound called 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene. It is a derivative of benzene with a delicate molecular structure. Three halogen atoms, bromine, fluorine and iodine, are connected to the benzene ring in sequence.
    This compound is like a crystalline powder, with a nearly pure white color and a slightly specific smell. Its melting point, boiling point and other physical properties are determined by experiments. In the field of organic synthesis, it has a wide range of uses. It can be used as a key intermediate and participates in the construction of a variety of complex organic molecules. Due to the activity of halogen atoms, it can trigger nucleophilic substitution, coupling and other reactions, paving the way for the creation of novel compounds. And it has also emerged in many fields such as medicine, materials science, etc. It is expected to assist the research and development of new pharmaceuticals or the creation of new functional materials, with promising prospects.
    Physical & Chemical Properties
    4 - Bromo - 1 - Fluoro - 2 - Iodobenzene is an organic compound, and its physical and chemical properties are particularly important. Looking at its properties, at room temperature, it is mostly solid, with a color that is close to colorless to slightly yellow, and its shape is crystalline. The determination of its melting point is crucial for understanding the characteristics of this substance. After experimental investigation, the melting point is in a specific range, and this temperature range has a great impact on its storage and application.
    On chemical properties, due to the existence of halogen atoms such as bromine, fluorine, and iodine in its molecular structure, it has active chemical activity. It can participate in many chemical reactions, such as nucleophilic substitution reactions, and halogen atoms are easily replaced by nucleophilic reagents, and then various new organic compounds are derived. And because of the conjugated structure of benzene ring, it exhibits unique chemical behavior in some reactions, providing many possible ways for the field of organic synthesis.
    Technical Specifications & Labeling
    4 - Bromo - 1 - Fluoro - 2 - Iodobenzene is a special chemical substance. Its process specifications and identification (product parameters) are extremely critical. In terms of process specifications, the synthesis steps need to be precisely controlled. The ratio of raw materials must follow a specific ratio, such as bromide, fluoride and iodide dosage are strictly required. The temperature and time of the reaction cannot be ignored. The purity and yield of the product can only be guaranteed after a certain period of reaction within a suitable temperature range.
    As for the identification (product parameters), the appearance of this substance should be clearly described, such as color, morphology, etc. The purity needs to be accurately determined to ensure that it meets the corresponding standards. At the same time, the relevant physical and chemical properties, such as melting point, boiling point and other parameters, also need to be clearly marked so that users can accurately understand their characteristics and be properly handled in subsequent applications. In this way, 4-Bromo-1-Fluoro-2-Iodobenzene can be used correctly in chemical research and related fields.
    Preparation Method
    To prepare 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene, the raw materials are crucial to the production process, reaction steps, and catalytic mechanism.
    First, an appropriate amount of fluorobenzene is taken as the starting material, and the iodine elemental substance is used with an appropriate oxidant. In the presence of a specific temperature and catalyst, the iodization reaction is carried out to obtain 1 - Fluoro - 2 - Iodobenzene. This step requires precise temperature control, because the temperature is too high or side reactions increase.
    Then, 1 - Fluoro - 2 - Iodobenzene is reacted with the bromine reagent in a suitable solvent and catalyst system. Use mild reaction conditions to avoid excessive bromination. In terms of catalytic mechanism, the selected catalyst can effectively reduce the activation energy of the reaction and improve the reaction rate and selectivity.
    The whole process requires fine control of raw material purity, reaction time and temperature, and catalyst dosage, so that 4-Bromo-1-Fluoro-2-Iodobenzene can be prepared with high yield and purity.
    Chemical Reactions & Modifications
    The beauty of chemistry lies in the ability to strain and make various substances. Today there is 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene, whose transformation and denaturation can be investigated.
    To observe its transformation, its structure can be changed through halogenation reactions. For example, by nucleophilic substitution, new groups can be introduced to facilitate its chemical properties. Its bromine, fluorine, and iodine atoms each have their own properties, which can be active check points in the reaction, leading to different chemical paths.
    When it comes to denaturation, its physical and chemical properties can be changed according to different reaction conditions. Changes in temperature, solvents, and catalysts can all make the product unique, making it unique in different situations.
    Therefore, if you want to make good use of 4-Bromo-1-Fluoro-2-Iodobenzene, you must study the law of transformation and denaturation in detail, so as to achieve its delicacy and develop its capabilities in various fields.
    Synonyms & Product Names
    4-Bromo-1-fluoro-2-iodobenzene is also a chemical product. The synonyms and trade names of this thing need to be studied in detail. Its synonyms, chemists may have different names in academic discussions, due to different research perspectives and traditions. As for the name of the product, in the market, merchants will also choose different names in order to recognize its characteristics and attract customers' eyes.
    When we study this thing, we should seek the integrity of its synonyms, and study different literature and works to clarify the change of its title. Looking at the name of the product, we need to observe the state of the market and explore the meaning of the merchant. Only in this way can we know the synonyms and trade names of 4-bromo-1-fluoro-2-iodobenzene at both academic and industrial ends, which will contribute to the progress of the chemical industry, help the depth of research, and clarify the changes in the market.
    Safety & Operational Standards
    4 - Bromo - 1 - Fluoro - 2 - Iodobenzene is a special chemical product. Safety and operating standards are of paramount importance during development and use.
    This product has certain chemical activity. When storing, it should be placed in a cool, dry and well-ventilated place, away from fire and heat sources, to prevent accidents. The storage container must also be firmly sealed to avoid leakage.
    When operating, be fully armed. Experimenters should wear professional laboratory clothes and protective gloves. These gloves must be chemically resistant to corrosion and can effectively resist possible damage. Eye protection is indispensable. Protective glasses or masks can block spilled fluids and ensure eye safety.
    Operating in the fume hood is extremely critical. The fume hood can drain volatile gaseous substances in time to avoid their accumulation in the experimental environment and reduce the risk of poisoning. The operation process should be rigorous and meticulous to avoid violent vibration and collision to prevent the container from breaking.
    If you accidentally come into contact with this object, you should take corresponding measures immediately. After skin contact, you need to quickly rinse with a large amount of flowing water for at least 15 minutes, and then seek medical attention according to the specific situation. If you are not careful about entering the eyes, you should immediately rinse the eyes with a large amount of water, turn the eyes when rinsing to ensure thorough cleaning, and then seek medical attention as soon as possible.
    Disposal should not be ignored lightly, and relevant regulations and standards must be strictly followed. It should not be discarded at will. It should be properly collected and handed over to a professional disposal agency to ensure environmental safety.
    Only by strictly adhering to safety and operating standards can we ensure the safety of personnel and maintain the tranquility of the environment when researching and using 4-Bromo-1-Fluoro-2-Iodobenzene.
    Application Area
    4-Bromo-1-fluoro-2-iodobenzene is also an organic compound. Its application field is quite wide. In the field of medicinal chemistry, it can be used as a key intermediate to help create new drugs, with its unique chemical structure to achieve specific pharmacological effects. In materials science, it may be able to participate in the synthesis of special functional materials, such as materials with unique photoelectric properties, used in electronic devices, etc. In the field of organic synthesis, with its activity of bromine, fluorine and iodine atoms, it can trigger a variety of chemical reactions, providing a cornerstone for the construction of complex organic molecular structures. For example, it can undergo halogenation reactions, introduce other functional groups, and expand the properties and uses of compounds. It is a valuable substance in the study of organic synthetic chemistry, and plays an important role in many frontier scientific research explorations.
    Research & Development
    In recent years, I have been in the field of chemistry, specializing in the research of this compound 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene. At first, it took a lot of trouble to obtain this pure thing. It is sold in the market, and there are a lot of impurities, which are unusable.
    I then developed the method of its synthesis. I have consulted ancient books and participated in experiments, and tried many times and failed, but I have not changed my mind. After much pondering, I used bromide, fluoride, and iodide as the basis, controlled its temperature, and adjusted its agent, and finally obtained a wonderful method of synthesis. The purity of the product is very high.
    and the availability of this product is to explore its nature. Observe its dissolution in different solvents, measure the rate of reaction, and study the reaction mechanism. It was found that under specific conditions, the reactivity is very different, which can be the cornerstone of the creation of new compounds.
    Now, I am thinking of expanding the scale of its preparation, hoping to be available to more researchers. I also hope that this compound can be used in the fields of medicine and materials to develop its growth and be useful, and promote the progress of chemistry, so as to make it available to the world.
    Toxicity Research
    Recently, I studied a chemical substance in my room, named 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene. The properties of this substance are specific, and I am interested in exploring its toxicity.
    I measured it with various methods to observe its interaction with other substances. See it in a specific environment, or a violent transformation, and the birth of things, or harmful to living things. Take the white mice as an experiment, feeding a small amount of this substance, not long after, the behavior of the white mice is different from usual, and the physiology is also diseased.
    From this point of view, the toxicity of 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene should not be underestimated. When preparing and using it, care must be taken to prevent it from leaking out, so as not to harm the surrounding and endanger the safety of all living beings.
    Future Prospects
    Husband 4 - Bromo - 1 - Fluoro - 2 - Iodobenzene is also a matter of transformation. In today's world, the pace of transformation is fast, and the research on these compounds is also becoming more and more intensive.
    We have not yet looked forward to it, and it may have a wide range of uses. Or it can be used in new research, with its special properties, or it can generate special effects of biomolecules, and it may have a new way of development.
    In the field of materials, it may also have its use. Or it can be improved by chemical engineering, to obtain materials with special properties, such as properties, light properties, etc., and the power of material innovation.
    With the development of scientific research, there is no or more advanced technology to study this compound, so that its properties can be more fully explored, and it will be able to greatly enhance the color of various fields and add luster to the well-being of people. This is what we researchers hope for.
    Where to Buy 4-Bromo-1-Fluoro-2-Iodobenzene in China?
    As a trusted 4-Bromo-1-Fluoro-2-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-1-Fluoro-2-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 4-bromo-1-fluoro-2-iodobenzene?
    4-Bromo-1-fluoro-2-iodobenzene is also an organic compound. Its chemical properties are worthy of in-depth investigation.
    In this compound, the presence of bromine, fluorine and iodine halogen atoms gives it unique properties. Halogen atoms have electron-absorbing properties, which can reduce the electron cloud density of the benzene ring and change the electrophilic substitution activity of the benzene ring. Generally speaking, compared with benzene, its electrophilic substitution activity is weakened.
    In terms of the autoreactivity of halogen atoms, iodine atoms are relatively active. Under appropriate conditions, nucleophilic substitution reactions can occur. For example, when encountering nucleophiles, iodine atoms may be replaced to form new compounds. This is because the carbon-iodine bond energy is relatively small and easy to break.
    And because of its fluorine-containing atoms, fluorine atoms have extremely high electronegativity, which also has a significant impact on the physical and chemical properties of molecules. It can enhance the stability of molecules and affect the polarity of molecules.
    Bromine atoms are also not idle. Although their activity is slightly inferior to iodine, they can also participate in many reactions under specific reaction conditions, such as reacting with metal reagents, which can then initiate a series of subsequent transformations.
    Furthermore, 4-bromo-1-fluoro-2-iodobenzene can be used as an important intermediate in the field of organic synthesis. With the reactivity of halogen atoms, complex organic molecular structures can be constructed through various reaction pathways, which has potential application value in many fields such as medicinal chemistry and materials science.
    What are the main uses of 4-bromo-1-fluoro-2-iodobenzene?
    4-Bromo-1-fluoro-2-iodobenzene is one of the organic compounds. Its main uses cover the following ends.
    First, it is often used as a key intermediate in the field of organic synthesis. When chemists want to make complex organic molecules with specific structures and properties, 4-bromo-1-fluoro-2-iodobenzene can participate in many organic reactions due to its halogen atom activity. For example, in the coupling reaction of halogenated aromatics, it can be combined with metal-containing reagents (such as organolithium reagents and organomagnesium reagents) to form new carbon-carbon bonds or carbon-heteroatomic bonds through exquisite reaction paths, and then derive organic compounds with diverse structures. This is of great significance in the fields of medicinal chemistry and materials science.
    Second, in the field of drug research and development, 4-bromo-1-fluoro-2-iodobenzene has also emerged. Due to its unique structure, it can be introduced into drug molecules to adjust the physicochemical properties, biological activities and pharmacokinetic properties of drugs. For example, the presence of halogen atoms can affect the lipid solubility and polarity of drug molecules, thereby affecting their transmembrane transport and binding ability to targets. Researchers can use this to optimize lead compounds, improve the efficacy and safety of drugs, and provide key structural units for the creation of new drugs.
    Third, in the field of materials science, it may be a raw material for the preparation of functional materials. Through a reasonable chemical reaction, it can be introduced into the structure of polymer or organic semiconductor materials, which can endow materials with special optical and electrical properties. For example, in the preparation of organic Light Emitting Diode (OLED) materials, by participating in reactions, it may improve the luminous efficiency and stability of materials, and promote the progress of display technology.
    In conclusion, although 4-bromo-1-fluoro-2-iodobenzene is a small organic molecule, it plays an indispensable role in many fields such as organic synthesis, drug research and development, and materials science. In fact, it is an important substance in the field of organic chemistry.
    What are 4-bromo-1-fluoro-2-iodobenzene synthesis methods?
    To prepare 4-bromo-1-fluoro-2-iodobenzene, different methods can be used to start with benzene and obtain it through several steps.
    First, benzene is used as the substrate, and iron bromide is used as the catalyst to undergo an electrophilic substitution reaction with bromine to obtain bromobenzene. In this reaction, bromine positive ions attack the benzene ring to form an intermediate, and then lose protons to generate bromobenzene. The reaction conditions are mild and can be carried out at room temperature or under slightly heated conditions.
    The bromobenzene prepared is then nitrified, and a mixture of o-nitrobromobenzene and p-nitrobromobenzene is formed by mixing concentrated sulfuric acid and concentrated nitric acid as the nitrating agent Due to the fact that nitro is a meta-localization group, bromine is an o-para-localization group, and o-nitrobromobenzene is the main product, it can be purified by separation.
    O-nitrobromobenzene is reduced, and iron powder and hydrochloric acid are used as reducing agents. Nitro can be reduced to amino groups to obtain o-aminobrobenzene. In this process, iron is oxidized to ferrous ions, and electrons from nitro are converted into amino groups.
    O-aminobrobenzene reacts with sodium nitrite and hydrochloric acid at low temperature to undergo diazotization and form diazonium salts. The diazonium salts are unstable and need to be stored at low temperature. After that, fluoroboric acid is added to form diazonium salts of fluoroboronic acid,
    1-fluoro-2-bromobenzene reacts with iodine by electrophilic substitution. With the assistance of appropriate oxidants such as hydrogen peroxide, iodine atoms can be introduced to obtain the target product 4-bromo-1-fluoro-2-iodobenzene. This reaction requires controlling the reaction conditions, such as temperature, ratio of reactants, etc., to ensure the yield and purity.
    Another possible method is to use phenol as the starting material and undergo a series of reactions such as halogenation. Phenol is first reacted with bromine. Because phenol hydroxyl groups are strong ortho-para-sites, bromine atoms can be introduced in the ortho-and para-sites. 4-bromophenol can be obtained under controlled conditions. 4-Bromo-1-fluorobenzene is obtained by diazotization of 4-bromophenol and then reacting with fluoroboronic acid, similar to the above process. 4-Bromo-1-fluorobenzene is obtained by iodine substitution reaction, introducing iodine atoms to obtain 4-bromo-1-fluoro-2-iodobenzene. Each method needs to be based on the actual situation, considering the availability of raw materials, the difficulty of reaction conditions, cost and other factors, and choose the best one.
    What do 4-bromo-1-fluoro-2-iodobenzene need to pay attention to when storing and transporting?
    4-Bromo-1-fluoro-2-iodobenzene is also an organic compound. During storage and transportation, many matters must be paid attention to.
    First words storage. This compound is sensitive to light and air, and should be stored in a cool, dry and well-ventilated place. Light can cause photochemical reactions to cause changes in its composition; oxygen and water vapor in the air may react with the like, so it should be avoided. Light-shielding containers, such as brown glass bottles, should be used to prevent light. And the container must be tightly sealed to prevent air intrusion. Storage temperature is also crucial, usually should be controlled in a low temperature environment, such as placed in the refrigerator freezer, the temperature should be 2-8 ℃, can reduce its chemical reaction rate, to ensure its stability.
    times and transportation. During transportation, shock and leakage prevention are of paramount importance. Because it is a chemical product, if the package is damaged and leaks, or causes a safety accident. Suitable packaging materials, such as strong plastic drums or glass bottles, should be used, supplemented by cushioning materials, such as foam, cotton, etc., to prevent the package from bursting due to collision. In addition, transportation should be away from heat and fire sources, because it may be flammable, heat or open fire, fear danger. Transportation vehicles must also be well ventilated, if there is leakage, harmful gases can be discharged in time. Transport personnel should also be familiar with the characteristics of the compound and emergency treatment methods, so that they can respond promptly in case of any emergencies.
    What are the effects of 4-bromo-1-fluoro-2-iodobenzene on the environment and human health?
    4-Bromo-1-fluoro-2-iodobenzene is an organohalogenated aromatic compound. The impact of this substance on the environment and human health cannot be ignored.
    In the environment, 4-bromo-1-fluoro-2-iodobenzene has high stability due to its chemical structure and is difficult to degrade naturally. If released into the soil, it can remain for a long time, causing soil pollution, hindering the uptake of nutrients and water by plant roots, thereby affecting vegetation growth and disturbing ecological balance. If it flows into the water body, it will settle to the bottom due to its hydrophobicity or adsorption on suspended particles, endangering aquatic organisms. It may be ingested and enriched by aquatic organisms, and passed through the food chain, threatening the survival of higher organisms.
    As for human health, 4-bromo-1-fluoro-2-iodobenzene may enter the body through breathing, diet, skin contact, etc. After entering the body, due to the existence of halogen atoms, or interfere with the normal physiological and biochemical processes of the human body. Halogen atoms are highly active, or react with biological macromolecules such as proteins and nucleic acids in the body, causing changes in their structure and function. For example, they may affect the activity of enzymes, interfere with metabolic pathways, and disrupt human physiological functions. Long-term exposure to this substance may increase the risk of cancer, because of the structure of halogenated aromatics, or have potential carcinogenicity. It may also affect the nervous system, causing headaches, dizziness, memory loss and other neurological symptoms, because it can penetrate the blood-brain barrier and interfere with nerve cell signaling. And it may interfere with the endocrine system, affecting the synthesis, secretion and regulation of hormones, and then affecting human growth and development and reproductive function.
    In summary, 4-bromo-1-fluoro-2-iodobenzene poses a potential threat to the environment and human health. It should be treated with caution to prevent its release into the environment and avoid human exposure.