4 Bromo 1 Iodo 2 Nitrobenzene
Iodobenzene

4 Bromo 1 Iodo 2 Nitrobenzene

Fengxi Chemical

Specifications

HS Code

623744

Chemical Formula C6H3BrINO2
Molecular Weight 326.80
Appearance Solid
Melting Point 92 - 96 °C
Boiling Point N/A
Density N/A
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Flash Point N/A
Purity Typically available in high purity (e.g., 95%+)
Name 4-bromo-1-iodo-2-nitrobenzene
Molecular Formula C6H3BrINO2
Molecular Weight 326.899 g/mol
Appearance Yellow solid
Melting Point 124 - 128 °C
Boiling Point 325.5 °C at 760 mmHg
Density 2.365 g/cm³
Flash Point 150.6 °C
Solubility In Water Insoluble
Purity Typically high - purity compounds are 95%+
Stability Stable under normal conditions but can react with strong oxidizing agents
Name 4-bromo-1-iodo-2-nitrobenzene
Molecular Formula C6H3BrINO2
Molecular Weight 326.80
Physical State At Room Temp Solid
Melting Point Data may vary, typically in a certain range, e.g., around 90 - 100 °C approximately
Density No standard value, but heavier than water due to halogens
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Odor Odorless or faint, non - characteristic smell
Name 4-bromo-1-iodo-2-nitrobenzene
Molecular Formula C6H3BrINO2
Molecular Weight 326.899 g/mol
Appearance Solid (Typical organic solid appearance, often off - white to pale yellow)
Melting Point Data may vary, around 100 - 110°C approximately
Boiling Point Estimated to be relatively high due to aromatic structure, likely > 250°C
Solubility In Water Insoluble in water due to non - polar aromatic and hydrophobic halogen and nitro groups
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform, toluene
Stability Stable under normal conditions, but may react with strong reducing agents, strong bases or nucleophiles
Packing & Storage
Packing 100g of 4 - bromo - 1 - iodo - 2 - nitrobenzene in a sealed, labeled chemical bottle.
Storage 4 - bromo - 1 - iodo - 2 - nitrobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent moisture and air exposure, which could potentially cause degradation. Store it separately from oxidizing agents and reducing agents to avoid dangerous reactions. Label the storage clearly for easy identification and safety.
Shipping 4 - bromo - 1 - iodo - 2 - nitrobenzene is shipped in well - sealed containers, following strict chemical transportation regulations. Packaging safeguards against breakage, with labels indicating its hazardous nature for safe handling during transit.
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4-bromo-1-iodo-2-nitrobenzene 4-bromo-1-iodo-2-nitrobenzene 4-bromo-1-iodo-2-nitrobenzene
General Information
Frequently Asked Questions
What are the chemical properties of 4-bromo-1-iodo-2-nitrobenzene?
4-Bromo-1-iodine-2-nitrobenzene is also an organic compound. It has the dual characteristics of halogenated aromatics and nitro compounds.
First of all, its halogen atom characteristics. Bromine and iodine atoms are active and can participate in many nucleophilic substitution reactions. When encountering nucleophilic reagents, such as sodium alcohol, amines, etc., halogen atoms can be replaced. Taking sodium alcohol as an example, bromine or iodine can be replaced by alkoxy groups to obtain corresponding aryl ethers. This reaction is commonly used in organic synthesis and can increase the functional group types of molecules.
Furthermore, the influence of nitro groups. Nitro has strong electron absorption, which can reduce the electron cloud density of benzene rings and weaken the electrophilic substitution reaction activity of benzene rings. However, due to the nitro group, the acidity of the o-para-hydrogen atom is enhanced, and it can be formed into a salt when it encounters a strong base. And the nitro group can be reduced, such as iron and hydrochloric acid, hydrogen and catalyst systems, which can be reduced to amino groups, so it can be prepared into compounds containing amino groups, which are important intermediates for the synthesis of medicines, dyes and so on.
4-bromo-1-iodine-2-nitrobenzene contains halogen atoms and nitro groups, and has unique reactivity. It is widely used in the field of organic synthesis and can be converted into organic compounds with diverse structures through various reactions.
What are the main uses of 4-bromo-1-iodo-2-nitrobenzene?
4-Bromo-1-iodine-2-nitrobenzene is also an organic compound. Its main use is mostly related to the field of organic synthesis.
In the art of organic synthesis, this compound is often an important raw material or intermediate. In its molecular structure, bromine, iodine and nitro each have unique chemical activities. Bromine and iodine atoms can introduce other functional groups or structural fragments by means of nucleophilic substitution reactions to build more complex organic molecules. Nitro is also an extraordinary substance, which can be converted into other functional groups such as amino groups through reduction and other reactions, thus paving the way for the synthesis of various nitrogen-containing organic compounds.
In the field of medicinal chemistry, the delicate products of organic synthesis are often the cornerstone of the creation of new drugs. 4-Bromo-1-iodine-2-nitrobenzene or because of its structural characteristics, can participate in the synthesis of compounds with specific physiological activities. After subsequent research and development, it may become a good medicine for treating diseases.
Furthermore, in the field of materials science, organic synthesis products can be used to prepare materials with special properties. 4-Bromo-1-iodine-2-nitrobenzene is involved in the synthesis of compounds, or due to its unique photoelectric, thermal and other properties endowed by its structure, it plays an important role in the preparation of new materials, such as organic optoelectronic materials.
In summary, 4-bromo-1-iodine-2-nitrobenzene is an organic compound, but it has many uses in organic synthesis, pharmaceutical chemistry and materials science. It is a valuable existence in the field of organic chemistry.
What are 4-bromo-1-iodo-2-nitrobenzene synthesis methods?
There are several common methods for the synthesis of 4-bromo-1-iodine-2-nitrobenzene. First, benzene can be started. First, benzene is nitrified with mixed acid (a mixture of nitric acid and sulfuric acid) to obtain nitrobenzene. In this step, nitric acid generates nitroyl positive ions (NO 2) under the action of sulfuric acid, which attack the benzene ring and undergo an electrophilic substitution reaction to generate nitrobenzene. Then, p-nitrobenzene reacts with bromine in the presence of catalysts such as iron bromide. Because the nitro group is the meta-site group, the bromine atom will enter the inter-nitro position to obtain m-bromo nitrobenzene. Finally, under appropriate conditions, m-bromo nitrobenzene undergoes a nucleophilic substitution reaction with iodide, and the iodine atom replaces the halogen atom in the appropriate position (such as the bromine atom is replaced by iodine) to obtain 4-bromo-1-iodine-2-nitrobenzene.
Second, o-nitroaniline can also be started from o-nitroaniline. The o-nitroaniline is first reacted by diazotization, with sodium nitrite and hydrochloric acid at low temperature to form a diazonium salt. Next, the diazonium salt is reacted with a cuprous halogen such as cuprous bromide, and the diazonium group is replaced by a The target product 4-bromo-1-iodine-2-nitrobenzene was formed by nucleophilic substitution reaction of o-nitrobromobenzene with iodide.
Furthermore, other aromatic compounds can be used as starting materials. According to the basic reaction principles of organic synthesis, such as electrophilic substitution, nucleophilic substitution, oxidation, reduction, etc., through rational design of reaction routes, the required functional groups and molecular structures are gradually constructed, and finally 4-bromo-1-iodine-2-nitrobenzene is synthesized. These methods have their own advantages and disadvantages, and the appropriate synthesis path should be selected according to the actual situation, such as the availability of raw materials, the difficulty of reaction conditions, and the high or low yield.
4-bromo-1-iodo-2-nitrobenzene what are the precautions during storage and transportation?
4-Bromo-1-iodine-2-nitrobenzene is an organic compound. When storing and transporting, many matters must be paid attention to to to ensure safety.
First storage. Because of its chemical activity, it should be stored in a cool, dry and well-ventilated place. High temperature and humidity, easy to cause chemical reactions, damage its quality, or even dangerous. The warehouse temperature should be controlled in a specific range, away from fire and heat sources to prevent accidents. And should be stored separately from oxidants, reducing agents, alkalis, etc., must not be mixed with storage, because of interaction or severe reaction, causing fire and explosion disaster.
Secondary packaging. The packaging material must have good sealing and corrosion resistance, which can effectively block the intrusion of air, moisture and other substances. It is commonly used in glass, plastic or metal containers, but the selected material must be compatible with the compound and not react with it. The name of the chemical, hazard characteristics, warning signs and other information should be clearly marked on the outside of the package, so that users and transporters can see at a glance and be vigilant.
Further transportation. The transportation process must follow relevant regulations and standards. Select suitable transportation tools to ensure that the container is stable and prevent package damage caused by collision and vibration. Transportation personnel should be professionally trained and familiar with chemical characteristics and emergency treatment methods. Pay close attention to the condition of the goods on the way. In case of leakage and other emergencies, they should be dealt with quickly according to the established plan to avoid the spread of hazards.
In addition, the storage and transportation places should be equipped with corresponding fire and emergency equipment, such as fire extinguishers, eye washers, protective equipment, etc. Periodically check the equipment to ensure that it is fully functional and ready for emergencies. In this way, it is necessary to ensure that 4-bromo-1-iodine-2-nitrobenzene is safe during storage and transportation.
What are the effects of 4-bromo-1-iodo-2-nitrobenzene on the environment and human health?
4-Bromo-1-iodine-2-nitrobenzene is one of the organic compounds. Its impact on the environment and human health cannot be ignored.
As far as the environment is concerned, if such compounds are released in nature, their structure contains bromine, iodine, nitro, etc., they have certain chemical stability and are difficult to be easily decomposed by the natural environment. They may remain in soil and water bodies, causing damage to soil fertility and affecting plant growth. In water bodies, it can affect the survival and reproduction of aquatic organisms. It may be transmitted through the food chain, bioaccumulation, and endangering high-level biological populations.
As for human health, 4-bromo-1-iodine-2-nitrobenzene may be toxic. After respiration, skin contact or ingestion, nitro can cause oxidative stress in human cells and damage the normal function of cells. Bromine and iodine atoms may interfere with the human endocrine system and affect hormone balance. Long-term exposure to this compound may increase the risk of cancer, because nitrobenzene substances have been suspected of carcinogens. And may damage the nervous system, causing headaches, dizziness, fatigue and other diseases. Therefore, in the production and use of products containing 4-bromo-1-iodine-2-nitrobenzene, care should be taken to prevent it from escaping into the environment to protect the environment and human health.