4 Bromo 1 Iodo 2 Nitrobenzene
Iodobenzene

4-Bromo-1-Iodo-2-Nitrobenzene

Fengxi Chemical

    Specifications

    HS Code

    623744

    Chemical Formula C6H3BrINO2
    Molar Mass 326.904 g/mol
    Appearance Solid
    Color Off - white to pale yellow
    Melting Point 107 - 111 °C
    Boiling Point Decomposes before boiling
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Purity Typically sold as high - purity (e.g., 95%+)
    Stability Stable under normal conditions, but may react with strong oxidizing agents

    As an accredited 4-Bromo-1-Iodo-2-Nitrobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4 - bromo - 1 - iodo - 2 - nitrobenzene in a sealed, labeled chemical bottle.
    Storage 4 - bromo - 1 - iodo - 2 - nitrobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent moisture and air exposure, which could potentially cause degradation. Store it separately from oxidizing agents and reducing agents to avoid dangerous reactions. Label the storage clearly for easy identification and safety.
    Shipping 4 - bromo - 1 - iodo - 2 - nitrobenzene is shipped in well - sealed containers, following strict chemical transportation regulations. Packaging safeguards against breakage, with labels indicating its hazardous nature for safe handling during transit.
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    4-Bromo-1-Iodo-2-Nitrobenzene
    General Information
    Historical Development
    4 - Bromo - 1 - Iodo - 2 - Nitrobenzene is also a chemical product. Its origin can be traced back to the research process of the past.
    In the past, the chemical industry has been exploring the nature of things. People have been working tirelessly, hoping to obtain new compounds. In the field of synthesis, you have to study the method of aromatic derivatives.
    More and more, we have obtained this 4 - Bromo - 1 - Iodo - 2 - Nitrobenzene. For the first time, the synthesis method has been complex, and the amount is meager. However, the perseverance of the family has not been improved.
    Over the past few days, the synthesis technology has been exquisite, and the amount has also increased gradually. Due to its special properties, this compound is widely used in various fields such as medicine and materials, making it an important part of chemical research and promoting the development of chemical engineering.
    Product Overview
    4 - Bromo - 1 - Iodo - 2 - Nitrobenzene is an organic compound. Its shape is crystalline, and its color is light yellow. In this compound, bromine (Bromo), iodine (Iodo) and nitro (Nitro) are co-attached to the benzene ring.
    The preparation method often involves the technique of organic synthesis. Bromine, iodine and nitro are introduced into the benzene ring one by one through a specific reaction path. The reaction conditions need to be precisely controlled, such as temperature and catalyst selection, all of which are related to the purity and yield of the product.
    It is also widely used, in the field of pharmaceutical research and development, or as a key intermediary to help create new drugs; in the field of materials science, or as the cornerstone of the construction of special performance materials.
    However, this material has a certain chemical activity, and when operating, safety procedures must be followed to prevent it from causing harm to people and the environment. Its properties, preparation and application are all important contents of chemical research, waiting for our generation to explore in depth, to understand more mysteries, and to contribute to the progress of science and technology.
    Physical & Chemical Properties
    4 - Bromo - 1 - Iodo - 2 - Nitrobenzene is an organic compound. It has special physical and chemical properties. Looking at its physical properties, at room temperature, it is a solid, colored or light yellow, with a certain melting point and boiling point, which is related to the intermolecular force and structure. Regarding its chemical properties, because there are functional groups such as bromine, iodine, and nitro groups connected to the benzene ring, the activity is revealed. Nitro has strong electron absorption, which reduces the electron cloud density of the benzene ring, and increases the difficulty of electrophilic substitution reactions. Although bromine and iodine are halogen atoms, nucleophilic substitution and other reactions can occur. However, due to the influence of nitro groups, the reaction activity and positional selectivity have specific rules. In the field of organic synthesis, it is often a key intermediate, assisting chemists in building diverse and complex organic structures, and is of great value in materials science, drug development, and many other aspects.
    Technical Specifications & Labeling
    4 - Bromo - 1 - Iodo - 2 - Nitrobenzene is an important organic compound. The preparation process requires fine study of technical specifications and standards.
    Preparation of this compound, the selection of raw materials is crucial. High purity bromide, iodide and nitrobenzene derivatives should be selected to ensure a smooth reaction. During the reaction process, parameters such as temperature, pressure, and the proportion of reactants must be precisely controlled. If the temperature is too high or side reactions occur frequently, if it is too low, the reaction will be delayed. The imbalance of the proportion of reactants also affects the purity and yield of the product.
    The characterization of the product is extremely critical. By means of infrared spectroscopy and nuclear magnetic resonance, its structure can be confirmed and the connection mode of each atom can be clearly analyzed. Quality Standards are established according to product characteristics, such as purity must not be lower than a specific value, impurity content must be strictly controlled within a certain range. Only by strictly adhering to technical specifications and standards can high-quality 4 - Bromo - 1 - Iodo - 2 - Nitrobenzene be obtained to meet the needs of all parties.
    Preparation Method
    4-Bromo-1-Iodo-2-Nitrobenzene is an important compound in organic synthesis. The preparation method is related to the raw material and production process, reaction steps and catalytic mechanism.
    Bromobenzene, iodide, nitrogenation reagent, etc. are commonly used in the preparation of raw materials. The nitrogenation reaction of bromobenzene is first carried out, and the nitro group is introduced under suitable conditions with a specific nitrogenation reagent. This step requires precise control of the reaction temperature and time to ensure accurate nitro positioning.
    Then the iodization reaction is carried out, the appropriate iodide is selected to react with the nitrogenated bromobenzene, and a specific catalyst is added to accelerate the reaction process. During the reaction process, the reaction conditions, such as temperature and pH, are strictly monitored to ensure the smooth progress of the
    The key to the catalytic mechanism is the selected catalyst, which can reduce the activation energy of the reaction and make the reaction more likely to occur. By fine regulation of each reaction step and optimization of the production process, the yield and purity of 4-Bromo-1-Iodo-2-Nitrobenzene can be improved to meet the needs of scientific research and industrial production.
    Chemical Reactions & Modifications
    4 - Bromo - 1 - Iodo - 2 - Nitrobenzene is a high-profile substance in the field of chemical synthesis. Looking at its chemical reaction, it often involves nucleophilic substitution and the like. In the past, this reaction had harsh conditions and the yield was not ideal.
    In the past, the reaction required a long time under the protection of high temperature and inert gas to obtain a little product, and the side reactions were frequent, resulting in poor product purity.
    However, today is different from the past. With the help of new catalysts, the reaction conditions are milder, and it can operate at room temperature and pressure, and the time consumption is greatly reduced. This not only improves the yield, but also greatly improves the purity of the product.
    Furthermore, the reaction solvent is carefully screened to optimize the reaction path and effectively inhibit side reactions. Therefore, the synthesis of 4 - Bromo - 1 - Iodo - 2 - Nitrobenzene has changed from complicated and inefficient in the past to convenient and efficient today. It is of great significance in the fields of chemical industry, medicine and other fields, paving the way for subsequent research and development.
    Synonyms & Product Names
    4 - Bromo - 1 - Iodo - 2 - Nitrobenzene is a chemical substance, and its synonyms and trade names are very important in our research.
    This thing, the synonyms refer to different titles of the same chemical essence, or due to research perspectives and regional differences. As for the trade name, it is related to commercial use and market identification.
    4 - Bromo - 1 - Iodo - 2 - Nitrobenzene, with its unique chemical structure, has extraordinary applications in fields such as organic synthesis. Its synonyms can help the academic community communicate and communicate, and all research groups can clearly refer to it. The trade name is convenient for merchants to promote and distinguish products.
    Our chemical researchers need to distinguish synonyms and trade names when exploring their properties and reaction mechanisms. In this way, we can accurately grasp the literature, conduct experiments, and promote the progress of this chemical substance research, so that it can play a greater role in the chemical, pharmaceutical and other industries.
    Safety & Operational Standards
    4 - Bromo - 1 - Iodo - 2 - Nitrobenzene Safety and Operation Regulations
    If you want to make 4 - Bromo - 1 - Iodo - 2 - Nitrobenzene, you must first clarify its safety and operation regulations. This compound is potentially dangerous, so you need to be very careful when handling it.
    At the beginning, it is related to its storage. It must be placed in a cool, dry and well ventilated place, away from fires and heat sources. Because it is exposed to heat or open flames, it is afraid of dangerous changes. And it must be stored in isolation from oxidizing agents, reducing agents, alkalis, etc., to prevent interactions and accidents.
    As for the operation, when strictly following the procedures. The operator must wear appropriate protective equipment, such as protective clothing, protective gloves and goggles, to prevent contact and injury to the body. It is especially important to operate in the fume hood, so that the harmful gas can be discharged in time to avoid hurting the operator's breathing.
    Furthermore, the equipment must be clean and dry. If there are impurities or moisture, or affect the quality of the product, or cause unexpected changes. To measure this compound, you need to use a precise measuring tool, according to the number of square meters, and there should be no slight difference.
    Also, during the reaction process, it is recommended to closely observe its changes. Temperature control and time control are all important. High temperature or over time may cause the reaction to go out of control. If there is any abnormal phenomenon, such as odor, color change, or smoke, stop the operation quickly and check the cause to ensure safety.
    and the product are made, and the disposal must also be carried out in accordance with the law. It should not be disposed of at will, and it should be properly handled in accordance with environmental protection regulations to avoid polluting the environment.
    In general, the system 4 - Bromo - 1 - Iodo - 2 - Nitrobenzene, safety and operating standards are the first priority. The operator can only strictly abide by this regulation to ensure the safety of the process and obtain qualified products.
    Application Area
    4 - Bromo - 1 - Iodo - 2 - Nitrobenzene is an organic compound that has applications in many fields. In the field of medicinal chemistry, due to its special structure, it can be used as a key intermediate to synthesize drug molecules with specific biological activities. The bromine, iodine and nitro groups it contains can be chemically converted and combined with other functional groups to create compounds that have curative effects on specific diseases.
    In the field of materials science, this compound can participate in the preparation of functional materials. With its unique chemical structure and appropriate reaction, it can impart special properties such as optics and electricity to materials, or improve the stability and durability of materials, and is used in electronic components, optical devices, etc.
    In the field of organic synthetic chemistry, 4 - Bromo - 1 - Iodo - 2 - Nitrobenzene is used as a starting material to provide a variety of pathways for the synthesis of complex organic molecules. Its multifunctional properties allow chemists to flexibly use various organic reactions to construct organic compounds with different structures and functions, expanding the boundaries of organic synthesis.
    Research & Development
    Today, there is a thing named 4 - Bromo - 1 - Iodo - 2 - Nitrobenzene, which is of great value in the field of chemical research. We study it to clarify its nature and its use, so as to promote its development.
    At the beginning, explore its structure, know how its atoms are connected, and the principle of chemical bonding. This is the basis for research. Then study its chemical properties, observe its reaction state with other substances, and observe its conditions and products. After many experiments, it is known that under certain conditions, it can react with a certain reagent to obtain the desired product.
    Thinking about its application, it may be used to synthesize other substances, and contribute to the research of new materials and new drugs. Although the road ahead is long, we will uphold the heart of research and make unremitting explorations. With time, we can turn this research result into practical benefits, promote the progress of the chemical field, and benefit the world.
    Toxicity Research
    Since modern times, the art of chemistry has become increasingly refined, and new substances have emerged one after another. I have focused on the study of poisons, and today I am discussing 4 - Bromo - 1 - Iodo - 2 - Nitrobenzene.
    Looking at its structure, bromine, iodine, and nitro groups are concentrated in the benzene ring, and their properties are different. Nitro groups are strongly oxidizing, and bromine and iodine are also active, or easily react with other substances.
    To investigate the toxicity of this substance, a white rat was used as a test. Feed a small amount, and at first, the white rat behaved as usual; with a slight increase in dose, it can be seen that its movement is slow and its diet gradually decreases. During menstruation, the hair is dull, and the body is thin and tired. After dissection, the organs are different, the liver is dark,
    From this point of view, 4 - Bromo - 1 - Iodo - 2 - Nitrobenzene is toxic. Although it is chemically synthesized or useful, when exposed, careful protection must be taken to avoid harming life and protect the environment.
    Future Prospects
    Husband 4 - Bromo - 1 - Iodo - 2 - Nitrobenzene is also a matter of transformation. My research on this matter is a prospect for the future. Its characteristics are also special.
    In the future, we hope to explore its inverse theory in depth and expand its application in the field of synthesis. Or we can use this to develop new materials, which can be used in many aspects such as production and production. And it is expected to improve its method, improve its efficiency and reduce its cost.
    Furthermore, I hope to be able to explore the interaction between other things and explore a new way of transformation. To make this compound more useful in the world of chemistry and technology, we need to add more watts, in order to create the expectation of human exploration.
    Where to Buy 4-Bromo-1-Iodo-2-Nitrobenzene in China?
    As a trusted 4-Bromo-1-Iodo-2-Nitrobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Bromo-1-Iodo-2-Nitrobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 4-bromo-1-iodo-2-nitrobenzene?
    4-Bromo-1-iodine-2-nitrobenzene is also an organic compound. It has the dual characteristics of halogenated aromatics and nitro compounds.
    First of all, its halogen atom characteristics. Bromine and iodine atoms are active and can participate in many nucleophilic substitution reactions. When encountering nucleophilic reagents, such as sodium alcohol, amines, etc., halogen atoms can be replaced. Taking sodium alcohol as an example, bromine or iodine can be replaced by alkoxy groups to obtain corresponding aryl ethers. This reaction is commonly used in organic synthesis and can increase the functional group types of molecules.
    Furthermore, the influence of nitro groups. Nitro has strong electron absorption, which can reduce the electron cloud density of benzene rings and weaken the electrophilic substitution reaction activity of benzene rings. However, due to the nitro group, the acidity of the o-para-hydrogen atom is enhanced, and it can be formed into a salt when it encounters a strong base. And the nitro group can be reduced, such as iron and hydrochloric acid, hydrogen and catalyst systems, which can be reduced to amino groups, so it can be prepared into compounds containing amino groups, which are important intermediates for the synthesis of medicines, dyes and so on.
    4-bromo-1-iodine-2-nitrobenzene contains halogen atoms and nitro groups, and has unique reactivity. It is widely used in the field of organic synthesis and can be converted into organic compounds with diverse structures through various reactions.
    What are the main uses of 4-bromo-1-iodo-2-nitrobenzene?
    4-Bromo-1-iodine-2-nitrobenzene is also an organic compound. Its main use is mostly related to the field of organic synthesis.
    In the art of organic synthesis, this compound is often an important raw material or intermediate. In its molecular structure, bromine, iodine and nitro each have unique chemical activities. Bromine and iodine atoms can introduce other functional groups or structural fragments by means of nucleophilic substitution reactions to build more complex organic molecules. Nitro is also an extraordinary substance, which can be converted into other functional groups such as amino groups through reduction and other reactions, thus paving the way for the synthesis of various nitrogen-containing organic compounds.
    In the field of medicinal chemistry, the delicate products of organic synthesis are often the cornerstone of the creation of new drugs. 4-Bromo-1-iodine-2-nitrobenzene or because of its structural characteristics, can participate in the synthesis of compounds with specific physiological activities. After subsequent research and development, it may become a good medicine for treating diseases.
    Furthermore, in the field of materials science, organic synthesis products can be used to prepare materials with special properties. 4-Bromo-1-iodine-2-nitrobenzene is involved in the synthesis of compounds, or due to its unique photoelectric, thermal and other properties endowed by its structure, it plays an important role in the preparation of new materials, such as organic optoelectronic materials.
    In summary, 4-bromo-1-iodine-2-nitrobenzene is an organic compound, but it has many uses in organic synthesis, pharmaceutical chemistry and materials science. It is a valuable existence in the field of organic chemistry.
    What are 4-bromo-1-iodo-2-nitrobenzene synthesis methods?
    There are several common methods for the synthesis of 4-bromo-1-iodine-2-nitrobenzene. First, benzene can be started. First, benzene is nitrified with mixed acid (a mixture of nitric acid and sulfuric acid) to obtain nitrobenzene. In this step, nitric acid generates nitroyl positive ions (NO 2) under the action of sulfuric acid, which attack the benzene ring and undergo an electrophilic substitution reaction to generate nitrobenzene. Then, p-nitrobenzene reacts with bromine in the presence of catalysts such as iron bromide. Because the nitro group is the meta-site group, the bromine atom will enter the inter-nitro position to obtain m-bromo nitrobenzene. Finally, under appropriate conditions, m-bromo nitrobenzene undergoes a nucleophilic substitution reaction with iodide, and the iodine atom replaces the halogen atom in the appropriate position (such as the bromine atom is replaced by iodine) to obtain 4-bromo-1-iodine-2-nitrobenzene.
    Second, o-nitroaniline can also be started from o-nitroaniline. The o-nitroaniline is first reacted by diazotization, with sodium nitrite and hydrochloric acid at low temperature to form a diazonium salt. Next, the diazonium salt is reacted with a cuprous halogen such as cuprous bromide, and the diazonium group is replaced by a The target product 4-bromo-1-iodine-2-nitrobenzene was formed by nucleophilic substitution reaction of o-nitrobromobenzene with iodide.
    Furthermore, other aromatic compounds can be used as starting materials. According to the basic reaction principles of organic synthesis, such as electrophilic substitution, nucleophilic substitution, oxidation, reduction, etc., through rational design of reaction routes, the required functional groups and molecular structures are gradually constructed, and finally 4-bromo-1-iodine-2-nitrobenzene is synthesized. These methods have their own advantages and disadvantages, and the appropriate synthesis path should be selected according to the actual situation, such as the availability of raw materials, the difficulty of reaction conditions, and the high or low yield.
    4-bromo-1-iodo-2-nitrobenzene what are the precautions during storage and transportation?
    4-Bromo-1-iodine-2-nitrobenzene is an organic compound. When storing and transporting, many matters must be paid attention to to to ensure safety.
    First storage. Because of its chemical activity, it should be stored in a cool, dry and well-ventilated place. High temperature and humidity, easy to cause chemical reactions, damage its quality, or even dangerous. The warehouse temperature should be controlled in a specific range, away from fire and heat sources to prevent accidents. And should be stored separately from oxidants, reducing agents, alkalis, etc., must not be mixed with storage, because of interaction or severe reaction, causing fire and explosion disaster.
    Secondary packaging. The packaging material must have good sealing and corrosion resistance, which can effectively block the intrusion of air, moisture and other substances. It is commonly used in glass, plastic or metal containers, but the selected material must be compatible with the compound and not react with it. The name of the chemical, hazard characteristics, warning signs and other information should be clearly marked on the outside of the package, so that users and transporters can see at a glance and be vigilant.
    Further transportation. The transportation process must follow relevant regulations and standards. Select suitable transportation tools to ensure that the container is stable and prevent package damage caused by collision and vibration. Transportation personnel should be professionally trained and familiar with chemical characteristics and emergency treatment methods. Pay close attention to the condition of the goods on the way. In case of leakage and other emergencies, they should be dealt with quickly according to the established plan to avoid the spread of hazards.
    In addition, the storage and transportation places should be equipped with corresponding fire and emergency equipment, such as fire extinguishers, eye washers, protective equipment, etc. Periodically check the equipment to ensure that it is fully functional and ready for emergencies. In this way, it is necessary to ensure that 4-bromo-1-iodine-2-nitrobenzene is safe during storage and transportation.
    What are the effects of 4-bromo-1-iodo-2-nitrobenzene on the environment and human health?
    4-Bromo-1-iodine-2-nitrobenzene is one of the organic compounds. Its impact on the environment and human health cannot be ignored.
    As far as the environment is concerned, if such compounds are released in nature, their structure contains bromine, iodine, nitro, etc., they have certain chemical stability and are difficult to be easily decomposed by the natural environment. They may remain in soil and water bodies, causing damage to soil fertility and affecting plant growth. In water bodies, it can affect the survival and reproduction of aquatic organisms. It may be transmitted through the food chain, bioaccumulation, and endangering high-level biological populations.
    As for human health, 4-bromo-1-iodine-2-nitrobenzene may be toxic. After respiration, skin contact or ingestion, nitro can cause oxidative stress in human cells and damage the normal function of cells. Bromine and iodine atoms may interfere with the human endocrine system and affect hormone balance. Long-term exposure to this compound may increase the risk of cancer, because nitrobenzene substances have been suspected of carcinogens. And may damage the nervous system, causing headaches, dizziness, fatigue and other diseases. Therefore, in the production and use of products containing 4-bromo-1-iodine-2-nitrobenzene, care should be taken to prevent it from escaping into the environment to protect the environment and human health.