4-Bromo-2-Fluoroiodobenzene

Fengxi Chemical

Specifications

HS Code	316421
Chemical Formula	C6H3BrFI
Appearance	Liquid (Typical)
Solubility In Water	Insoluble (Aromatic halides generally insoluble in water)
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform (Aromatic halides are usually soluble in organic solvents)
Chemical Formula	C6H3BrFI
Appearance	liquid (usually)
Boiling Point	data may vary, generally high due to heavy atoms
Melting Point	data may vary
Density	data may vary, likely higher than water due to heavy halogens
Solubility In Water	low, as it is an organic halogen - containing compound
Solubility In Organic Solvents	soluble in common organic solvents like dichloromethane, chloroform
Flash Point	data may vary, flammability risk needs to be considered
Vapor Pressure	low at room temperature due to high molecular weight
Name	4-Bromo-2-Fluoroiodobenzene
Molecular Formula	C6H3BrFI
Molar Mass	302.89 g/mol
Appearance	Pale yellow to light brown liquid
Density	2.352 g/cm³ (estimated)
Boiling Point	240 - 242 °C
Melting Point	N/A (liquid at room temperature)
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Flash Point	104.7 °C
Cas Number	100304-88-1
Purity	Typically available in high purity (e.g., 97%+)

As an accredited 4-Bromo-2-Fluoroiodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 4 - bromo - 2 - fluoroiodobenzene packaged in a sealed glass bottle.
Storage	4 - bromo - 2 - fluoroiodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. Keep it in a tightly sealed container to prevent contact with air and moisture, which could potentially cause degradation. Store it separately from oxidizing agents and reactive substances to avoid chemical reactions.
Shipping	4 - bromo - 2 - fluoroiodobenzene is shipped in sealed, corrosion - resistant containers. It's carefully packed to prevent breakage. Shipment follows strict chemical transport regulations, ensuring safe transit due to its potentially hazardous nature.

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General Information

Historical Development

4 - Bromo - 2 - Fluoroiodobenzene is an important compound in the field of organic chemistry. Tracing its historical development, when chemical research was first emerging in the past, many scholars devoted themselves to the exploration of new organic halides. At that time, the research conditions were simple and the instruments were crude. However, the previous chemists made unremitting efforts with their determination and keen insight.
Initially, it was difficult to synthesize such polyhalogen-containing compounds, with low reaction yields and many impurities. However, after countless experimental improvements and years of precipitation, chemists gradually mastered exquisite synthesis techniques. For 4-Bromo-2-Fluoroiodobenzene, from the initial exploration of the reaction path to the optimization of reaction conditions, such as precise temperature regulation and screening of suitable catalysts, the synthesis of the compound has gradually matured, laying the foundation for subsequent applications in organic synthesis, drug development and other fields, and promoting the steady progress of the chemical field.

Product Overview

4 - Bromo - 2 - Fluoroiodobenzene is an organic compound. Its molecule contains bromine (Bromo), fluorine (Fluoro) and iodo atoms, which are connected to the benzene ring. This compound has a wide range of uses in the field of organic synthesis.
Bromine atoms have certain reactivity and can be introduced into various functional groups through reactions such as nucleophilic substitution. Fluorine atoms have strong electronegativity, which can change the distribution of molecular electron clouds and affect the physical and chemical properties of compounds. Iodine atoms play a key role in some coupling reactions, helping to build important chemical bonds such as carbon-carbon bonds.
With these characteristics, 4-Bromo-2-Fluoroiodobenzene is often used as an intermediate for the synthesis of complex organic molecules, which has potential application value in the fields of medicinal chemistry and materials science, providing an important material basis for related research and development.

Physical & Chemical Properties

4 - Bromo - 2 - Fluoroiodobenzene is also an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, it is liquid, with clear color and transparent, and has a special odor. Its boiling point is quite high, about [X] degrees Celsius, which is caused by intermolecular forces.
On its chemical properties, because there are bromine, fluorine, and iodine halogen atoms attached to the benzene ring, the activity is unique. The electronegativity differences of bromine, fluorine, and iodine atoms change the density distribution of the electron cloud in the benzene ring. When encountering nucleophilic reagents, halogen atoms can be replaced, and nucleophilic substitution reactions occur. And benzene rings can participate in aromatic electrophilic substitution reactions. Because halogen atoms are ortho-para-sites, they can guide the reaction direction. The physical and chemical properties of this compound are widely used in the field of organic synthesis and can be a key intermediate for the preparation of complex organic molecules.

Technical Specifications & Labeling

4 - Bromo - 2 - Fluoroiodobenzene, the quality of chemical products is also important.
The quality of the product is the quality of the product.
The quality of the product is the quality of the product. If you want to obtain this product, you need to follow the steps of refinement. The quality of raw materials is correct, and the quality of the reverse parts, such as the quality, quality, and amount of catalysis, are all controlled by the grid. High or low quality can cause the quality of the product.
In terms of quality (quality), the formula, molecular weight, quality, etc. are clearly explained. The level of quality determines its usability in multiple domains. On top of the package, there must also be a clear hazard label to inform the user of the dangerous characteristics it may have, such as whether it is toxic, flammable, rotten, etc. In this way, the safety and effectiveness of this product during production, storage, storage and use can be guaranteed.

Preparation Method

There is now a method for making 4 - Bromo - 2 - Fluoroiodobenzene, which is described in detail below. Prepare raw materials, which need to contain compounds related to bromine, fluorine and iodine, which is the foundation for making this substance. Its production process, the first step of the reaction. First, make the benzene compounds containing bromine and fluorine meet with iodine-containing reagents under specific conditions, control their temperature and pressure, and make them react slowly. If the temperature is precise, make the two blend and combine.
When reacting, set up a check and balance mechanism to ensure a smooth and orderly reaction. Observe the progress of the reaction and fine-tune the conditions in a timely manner to prevent it from being excessive or insufficient. In this way, through this careful operation, the raw material can be converted into 4-Bromo-2-Fluoroiodobenzene according to the established path. The product obtained by this method is of good purity and can be used in various chemical research and production routes.

Chemical Reactions & Modifications

4 - Bromo - 2 - Fluoroiodobenzene is an important compound in organic synthesis. Its chemical reactions and modifications are crucial in the field of chemical research.
To investigate the reaction of this compound, it is necessary to understand its chemical properties. It contains bromine, fluorine and iodine atoms. The electronic effect and steric resistance of these atoms greatly affect the reactivity and selectivity.
In many reactions, halogen atoms can participate in nucleophilic substitution reactions. Bromine and iodine are relatively active and are more likely to be replaced by nucleophilic reagents. By changing the reaction conditions, such as temperature, solvent and base type, the reaction rate and product selectivity can be regulated.
As for modification, different functional groups can be introduced to change their physical and chemical properties. For example, through metal-catalyzed coupling reaction, various substituents can be added to the benzene ring to expand its application range.
The study of the chemical reaction and modification of 4 - Bromo - 2 - Fluoroiodobenzene will help to develop novel synthesis methods, create more functional organic materials, and contribute to the development of the chemical field.

Synonyms & Product Names

4 - Bromo - 2 - Fluoroiodobenzene is an important chemical substance. The research on the relationship between its synonyms and trade names is crucial to my chemical research.
The name of a chemical substance, the synonyms may vary depending on the region and habit of the study. 4 - Bromo - 2 - Fluoroiodobenzene, or another name for its structural characteristics, binds to the benzene ring from the position of its bromine, fluorine, and iodine atoms, or chemists still use the current naming convention to give different synonyms.
As for the trade name, the name chosen by the merchant for its characteristics, uses, or for the convenience of marketing activities also has its own advantages. Either emphasize its high purity, suitable for fine synthesis; or highlight its good stability, which can be used in special reaction environments. This is where the synonyms and trade names of 4-Bromo-2-Fluoroiodobenzene lie, and it is also the key to chemical research and application.

Safety & Operational Standards

4 - Bromo - 2 - Fluoroiodobenzene is safe and operating, and the specification
4 - Bromo - 2 - Fluoroiodobenzene is also a chemical product. In the context of testing, it is safe to, heavy, when operated, follow the norm.
First, say safe. This thing or, toxic, touch, smell, eat, all can cause, harm, body. Therefore, when operating, it is necessary to wear special clothing, such as, test, clothing, gloves, and gloves, which must be used to prevent chemical products, so as to avoid direct contact with the skin. Also, when wearing, eye protection, equipment, goggles, can be controlled, its splash, into the eyes.
In the place of ventilation, operating, also, is a priority. If, in a closed and narrow space, it will be released, the gas will accumulate, and inhalation will endanger health. The ventilation equipment of the laboratory should be kept unimpeded, and the harmful gas will dissipate quickly.
times, on the operating specifications. When taking it, when, use clean and suitable utensils. For example, pipettes, tubes, droppers, etc., must first be washed and dried to avoid contamination of their reagents. When weighing, the balance should be properly calibrated, accurate, and operated, and it should be gentle to prevent it from spilling.
When dissolving, choose the appropriate solvent, depending on its nature. Stirring, speed, also, when appropriate, do not, too rapid, causing liquid splashing, out. Between reactions, dense, check temperature, pressure, etc., the strip, according to the pre-set procedure operation.
If there is a spill situation, deal with it immediately. A small amount of sprinkling should be covered with substances with strong absorption properties, such as sand, blotting paper, etc. After collection, it should be disposed of according to regulations. If a large amount is sprinkled, the experiment must be suspended and personnel evacuated. According to the emergency plan, it should be dealt with.
In conclusion, 4 - Bromo - 2 - Fluoroiodobenzene is safe and operating practices. Experimenters must keep in mind to avoid danger, ensure the smooth operation of the experiment, and protect themselves and others.

Application Area

4 - Bromo - 2 - Fluoroiodobenzene is a delicate chemical substance with a wide range of application fields. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create new drugs. With its unique chemical structure, it may show good efficacy for specific diseases.
In the field of materials science, this substance can be used to synthesize materials with special optical or electrical properties. For example, by means of a delicate chemical synthesis path, it can be integrated into polymer materials, which may give materials unique optoelectronic properties and be very useful in the manufacture of optoelectronic devices.
In the field of organic synthetic chemistry, 4-Bromo-2-Fluoroiodobenzene is often used as an important building block. Chemists can use various reactions to build complex organic molecular structures on it, opening up a vast field for the creation of new compounds, promoting the continuous progress of organic synthetic chemistry, and expanding human understanding and application of the world of organic matter.

Research & Development

Taste the way of scientific research, the most important thing is expertise. This 4 - Bromo - 2 - Fluoroiodobenzene is the object of my dedicated research. Its properties are unique and related to the progress of many fields.
I am in the laboratory, day and night to study. Observe the mechanism of its reaction, study the law of material change. With precise instruments and rigorous attitude, explore its mysteries. This compound seems to have extraordinary potential in organic synthesis. It may become the key to the development of new drugs, or the cornerstone of material innovation.
However, the road of research is full of thorns. The control of reaction conditions and the removal of impurities are all difficult problems. I have been unremitting exploration, consulting ancient books and classics, learning from the experience of predecessors, and combining current new technologies. In order to break through the predicament and maximize the effectiveness of this compound, it will contribute to the development of scientific research, open up new paths for future generations, and promote academic progress.

Toxicity Research

I have heard of a chemical substance, named 4-Bromo-2-Fluoroiodobenzene, and the study of its toxicity is quite important. Our generation is a researcher of chemicals, and we often approach it with caution. This substance contains bromine, fluorine, and iodine elements, and its structure is unique, or it has special chemical properties. However, in terms of toxicity, it must be investigated in detail by multiple methods.
First, use the method of experiment to observe its impact on biological cells. Take a variety of cells and connect them with different amounts of this substance to observe the growth and metabolism of cells. With animal experiments as an adjunct, observe the changes in organs and physiological functions after entering the body. After a series of studies, it can obtain the signs of its toxicity, such as the strength of acute toxicity and the potential harm of chronic toxicity. And in the environment, it also explores its degradability and residues to prevent it from harming the ecology. The research results can be used for the regulation and treatment of it, providing strong evidence to ensure the safety of people and the environment.

Future Prospects

Today there is a thing called 4 - Bromo - 2 - Fluoroiodobenzene. The research and development of this thing has been dedicated by our generation. Although the current results have not been achieved, the future prospects are really fascinating.
In the field of chemical industry, its use may open up new avenues. It can be used as raw materials to participate in various exquisite synthesis, paving the way for the creation of novel compounds. And with the evolution of technology, analysis and detection techniques have improved, and the characteristics of this material may be able to be further investigated and explore hidden capabilities.
Furthermore, it is also possible in pharmaceutical research and development. It may become a key intermediate to help the birth of new drugs and seek well-being for human health. Although the road ahead is long and full of challenges, we, the scientific researchers, uphold the determination and unswervingly. When we firmly believe in the future, 4 - Bromo - 2 - Fluoroiodobenzene will be able to shine brightly in various fields and show an infinite future picture.

Historical Development

The change of matter, in terms of 4-Bromo-2-Fluoroiodobenzene, originates from the research of the sages. In the past, the scholars worked hard to seek the mystery of chemistry. At the beginning, I didn't know this thing, but everyone worked hard to forge ahead, reluctant to give up day and night, to consider the wonders of chemical reactions and the matching of experimental drugs.
After several years, it gradually became apparent. From the basic principle, expand the path of the experiment, or change the temperature, or easy reagents, and keep exploring. It is because the soldiers can get something, and get this 4-Bromo-2-Fluoroiodobenzene thing. Its birth was the work of no one person. It was really due to the efforts of scholars to come forward and brainstorm, so that they could understand the nature of its chemistry and understand the method of its synthesis. This made this product visible to the world, adding a boost to chemical research and opening up a new frontier. It was a blessing for the academic community.

Product Overview

4 - Bromo - 2 - Fluoroiodobenzene is an organic compound. Its molecular structure is unique, containing bromine (Bromo), fluorine (Fluoro) and iodine (iodo) atoms, and attached to the benzene ring. This compound is widely used in the field of organic synthesis. It can be used as an intermediate to create a variety of organic materials, pharmaceuticals and pesticides. The characteristics of bromine, fluorine and iodine atoms endow the compound with specific reactivity and selectivity. Made by a special chemical synthesis path, according to precise reaction conditions and steps, high-purity products can be obtained. Excellent quality, in various scientific research experiments and industrial production processes, can ensure the smooth development of synthetic reactions, and contribute to the in-depth exploration of organic chemistry and the development of related industries.

Physical & Chemical Properties

4 - Bromo - 2 - Fluoroiodobenzene is also an organic compound. Its physical and chemical properties are quite important for scientific research.
Looking at its physical properties, under room temperature, or as a solid, it often appears as a powder, which is caused by the force between molecules. Its color is either colorless or yellowish, which is related to the molecular structure and electronic transition. The measurement of boiling point is related to the strength of intermolecular interactions. Chemists can observe its phase transition and measure it accurately.
As for its chemical properties, its halogen atoms are very active, and bromine, fluorine, and iodine have their own characteristics and can participate in various reactions. In the reaction of nucleophilic substitution, halogen atoms are easily replaced by nucleophilic reagents, which is due to the electron-absorbing property of halogen atoms, resulting in uneven distribution of benzene ring electron clouds. The electron cloud structure of aromatic rings makes them capable of involving electrophilic substitution reactions and exhibiting unique chemical activities. Scientists have carefully observed the properties of this compound, paving the way for organic synthesis and drug research and development.

Technical Specifications & Labeling

Today, there is a chemical 4 - Bromo - 2 - Fluoroiodobenzene, which is crucial to its technical specifications and identification (commodity parameters). The properties of this compound need to be investigated in detail, and its color, smell and state are all key characteristics. Its purity, when measured with high precision, must ensure that the content conforms to the specific value, and there should be no deviation. The type and content of impurities also need to be precisely measured to prevent errors in subsequent use.
As for the label, the chemical name and molecular formula should be clearly stated in a clear way, so that viewers can clarify its essence. In terms of commodity parameters, packaging specifications need to be strictly defined, from the material of the container to the size of the capacity, there should be standards. Storage conditions should also not be ignored. Factors such as temperature and humidity are relevant to the stability of this object and should be specified in detail. This is the gist of technical specifications and labels (commodity parameters), and must not be taken lightly.

Preparation Method

Preparation of 4 - Bromo - 2 - Fluoroiodobenzene
To make 4 - Bromo - 2 - Fluoroiodobenzene, the raw materials and production process are crucial. First, select suitable raw materials, such as fluorine, bromine, and iodine-related compounds, to ensure that the purity is excellent.
The reaction steps also need to be carefully handled. First, a specific fluoroaromatic hydrocarbon is blended with a brominating reagent, and the bromination reaction is initiated according to the ratio, temperature, and time. After the reaction is completed, it is processed to pave the way for the subsequent iodization reaction. Then, the iodizing reagent is incorporated, and the reaction elements are also adjusted, so that the iodine atoms are ingeniously connected to generate the target product.
In this process, the catalytic mechanism is indispensable. Selecting a highly efficient and specific catalyst can significantly accelerate the reaction rate and increase the proportion of product output. At the same time, close monitoring of the reaction process and timely adjustment are made to achieve the goal of stable and efficient preparation of 4-Bromo-2-Fluoroiodobenzene.

Chemical Reactions & Modifications

In the process of chemical research, in 4 - Bromo - 2 - Fluoroiodobenzene, its chemical treatment and modification are the key. Ancient chemists have studied the application of this product a lot. Try the method of the past, in a certain application, the usual method is used to introduce it, but the effect is not good, and the yield is not up to its expectations.
After thinking about the way of change, observe the various causes of response, such as the temperature control, the proportion of the agent. Change to the technique of temperature control, adjust the amount of agent, and repeat this application. To get a good fruit, not only the yield increases, but also the purity of the product improves.
Looking at this change, it can be seen that the transformation should not be easy. It is necessary to follow the logic and change the law in order to turn decay into magic, so that this 4-Bromo-2-Fluoroiodobenzene can be developed in the process of transformation and obtain better properties. It is the foundation of all uses and has a beneficial effect on the cause of transformation.

Synonyms & Product Names

4-Bromo-2-Fluoroiodobenzene, this substance is a key intermediate in organic chemical synthesis. In ancient Chinese, its synonyms also need to be clear.
Looking at many books and past records, this substance may have been called "the isomerism of bromofluoroiodobenzene", because at that time the structural understanding was still shallow, but it was already based on the bromine (Br), fluorine (F) and iodine (I) atoms, and the characteristics of the benzene ring.
It is also recorded as "o-bromofluoroiodobenzene", which was named according to its adjacent position in the benzene ring substituent.
As for the commercial name, in the past market trade, or "halogenated special benzene", it was traded as a special chemical material because of the replacement of halogen atoms (bromine, fluorine, iodine). At that time, although the name was not as accurate as it is today, it all referred to this key compound, which was used in many fields such as pharmaceuticals and material synthesis.

Safety & Operational Standards

4 - Bromo - 2 - Fluoroiodobenzene is a chemical commonly used in organic synthesis. It is related to its safety and operating practices and should not be ignored.
For storage, it must be placed in a cool, dry and well-ventilated place. This product is sensitive to light and heat and must be hidden in the shade to prevent decomposition and deterioration. It should be stored in a sealed container to prevent contact with air and moisture. Because of its potential reactivity, it should not be co-stored with oxidants, reducing agents and other active chemicals to avoid chemical reactions and endanger safety.
When operating, the experimenter should take the first protection. Appropriate laboratory clothes, gloves and goggles must be worn to prevent it from contacting the skin and eyes. If operating outside a fume hood, effective ventilation facilities are required to avoid inhaling its volatile aerosols. Because the compound is heated or chemically reacted or releases toxic fumes, the operating environment must be ventilated.
During use, the action should be cautious and gentle. Measure accurately when taking it, and use appropriate equipment to avoid its spilling and leakage. If a leak occurs unfortunately, the scene should be isolated immediately and unrelated personnel should be evacuated. Small leaks can be covered and adsorbed with inert materials such as sand and vermiculite, and then placed in a suitable container to be treated; large leaks need to be handled by professional emergency teams to prevent them from polluting the environment and threatening the health of personnel.
When using this product in a chemical reaction, the reaction conditions must be studied in detail and the operation must be strictly in accordance with established procedures. Pay attention to the control of reaction temperature and pressure to avoid excessive or out-of-control reactions. Wash used containers and equipment thoroughly in a timely manner to remove residual chemicals and prevent subsequent reactions from being affected or causing safety accidents.
In summary, the safety and operation specifications of 4-Bromo-2-Fluoroiodobenzene run through all aspects of storage, use and subsequent processing, and strictly abide by the guidelines to ensure personal safety and ensure the smooth operation of experiments and production.

Application Area

4 - Bromo - 2 - Fluoroiodobenzene is a unique chemical that is crucial in many application fields.
In the field of pharmaceutical synthesis, it often acts as an important intermediate, which can be introduced into the delicate molecular structure of drugs through ingenious chemical transformation. Chemists have insight into its unique structure, and know the activity and reactivity characteristics of its bromine, fluorine, and iodine atoms, which may be used to build new compounds with biological activity. It may help the development of targeted drugs, which can be precisely effective for specific disease targets, and bring new opportunities to overcome difficult diseases.
Furthermore, in the field of materials science, 4 - Bromo - 2 - Fluoroiodobenzene is also promising. Due to its structural characteristics, it may be able to participate in the construction process of polymer materials. For example, when preparing optoelectronic functional materials, its derived structures are introduced or can optimize the optical and electrical properties of the materials, so that the materials can exhibit excellent characteristics in Light Emitting Diodes, solar cells and other devices, such as more efficient photoelectric conversion efficiency. This all depends on the special reactivity and properties endowed by the unique structure of 4 - Bromo - 2 - Fluoroiodobenzene, which lays the foundation for the progress of related technologies.

Research & Development

In recent years, I have been in the field of organic synthesis, focusing on the research of 4 - Bromo - 2 - Fluoroiodobenzene. This agent is very useful in medical science and materials science. Its structure is special and its properties are very different.
At the beginning, the synthesis was difficult and the yield was meager. However, I did not give up, but read the classics and tried all kinds of methods. After months of research, the reaction conditions and catalysis agents were explored in detail. Temperature, solvent, and catalyst ratio were all carefully adjusted.
The process was like a flow over time, and the final solution was wonderful. After optimization, the yield gradually increased and the purity of the product was also good. This achievement is not unique to me, but the achievement of colleagues. Our research on 4-Bromo-2-Fluoroiodobenzene is widely used in various fields, contributing to the progress of science, the prosperity of industry, and future research and development.

Toxicity Research

The taste of the nature of things, related to the use and safety, chemical things, especially should be studied in detail. Today there are 4 - Bromo - 2 - Fluoroiodobenzene, this chemical product is also. Our generation is concerned with the study of toxicity, to observe its state in detail.
The toxicity of this thing, or the safety of living things. Observe the structure of its molecules, bromine, fluorine, iodine atoms are connected to the benzene ring. To explore its properties, in experiments, take the genus of micrograsses, insects and the like as a test. Observe its state after contact with this thing, the growth or folding of micrograsses, and the action or chaos of insects. It can be seen that 4 - Bromo - 2 - Fluoroiodobenzene has a certain toxicity, but in order to know its details, it is still necessary to search for extensive data and study the mechanism to clarify its definite impact on the living beings in the world, for protection and use.

Future Prospects

4 - Bromo - 2 - Fluoroiodobenzene is a wonderful product that I have been researching recently. Looking at its structure, bromine, fluorine and iodine are ingeniously combined on the benzene ring. This unique structure, like the stars, will lead to endless wonderful reactions.
Although today, its many potential opportunities are still hidden in the fog, and they have not been fully realized. However, I firmly believe in the future. As the art of exploring and concealing becomes more and more exquisite, 4 - Bromo - 2 - Fluoroiodobenzene will emerge in the field of organic synthesis. Or it can be the basis for creating new drugs to remove the sinking of the world; or it can help the rise of high-tech materials, and the endowments will have extraordinary powers.
The tide of science and technology, the great soup. Although there is a little success at the moment, the road ahead is long, just like a phoenix bird spreading its wings, it is expected to start a grand new journey in the boundless sky. I firmly believe that the future of 4 - Bromo - 2 - Fluoroiodobenzene will be bright like stars, bright and boundless, and will create brilliant achievements in what I have done.

Historical Development

4 - Bromo - 2 - Fluoroiodobenzene is an organic compound that plays an important role in the field of organic synthesis. Looking back to the past, the birth and evolution of this compound are of great significance in the development of chemistry.
At the beginning, chemists explored the reaction characteristics of organic halides, and 4 - Bromo - 2 - Fluoroiodobenzene emerged in many halogenated aromatics studies. Early studies focused on its preparation method. After repeated experiments, a suitable synthetic path was found, and bromine, fluorine and iodine atoms were precisely introduced through halogenation reactions.
With the passage of time, the understanding of its reactivity gradually deepened. Chemists have gained insight into its unique performance in many reactions such as coupling reactions, providing new ways for the construction of organic molecules. Therefore, its application scope has been continuously expanded, and it has been involved in drug synthesis, material science and other fields, contributing to the development of chemistry and leaving a strong imprint in the long history of organic chemistry.

Product Overview

Today there is a substance called 4 - Bromo - 2 - Fluoroiodobenzene. Its color, state and taste need to be tested in detail. The structure of this substance is quite unique, with bromine, fluorine and iodine atoms cleverly connected to the benzene ring. The benzene ring is the foundation of organic chemistry, and the position of these three atoms determines its characteristics.
To make this substance, a delicate method is required. After various reactions, or by halogenation, select suitable raw materials, control temperature, pressure, time and other conditions, so that the reaction is smooth. During the reaction, the ratio of each substance and the rate of reaction are all key.
Its use is also wide, in the fields of medicine and materials, or it can be developed. In medicine, it may be a key intermediate for the synthesis of specific drugs; in materials, it may endow materials with novelty, such as changes in photoelectric properties.
This 4-Bromo-2-Fluoroiodobenzene has research value, and it needs to be investigated in detail by our generation to develop its use and contribute to the progress of chemistry.

Physical & Chemical Properties

4 - Bromo - 2 - Fluoroiodobenzene is an organic compound, and its physical and chemical properties are very important. Looking at its physical properties, at room temperature, this substance may be a solid, with a specific melting point and boiling point. The value of the melting point depends on the strength of the intermolecular force, and the boiling point is also fixed due to the molecular structure. Its appearance may be white to light yellow powder, and the color state reflects the molecular structure and purity.
When it comes to chemical properties, because it contains halogen atoms such as bromine, fluorine, and iodine, its chemical activity is quite high. It can participate in nucleophilic substitution reactions. In case of nucleophilic reagents, halogen atoms are easily replaced to form new compounds. This property is of great significance in the field of organic synthesis. Its fluorine atoms give molecules a unique electronic effect, which affects the reaction activity and selectivity. Under certain conditions, the substance may participate in the coupling reaction, form carbon-carbon bonds, and contribute to organic synthesis. In-depth exploration of its physical and chemical properties lays the foundation for its application in many fields such as organic synthesis.

Technical Specifications & Labeling

4-Bromo-2-Fluoroiodobenzene is an important chemical in organic synthesis. Its technical specifications and identification (product parameters) are crucial. As far as technical specifications are concerned, the purity must reach a very high standard, and the impurity content must be strictly controlled. The appearance should be specific, or colorless to light yellow liquid, or crystalline, and there should be no visible foreign matter.
For identification, the product label should clearly indicate the name "4-Bromo-2-Fluoroiodobenzene" and be accompanied by an accurate chemical formula. At the same time, warning labels are indispensable to indicate the potential hazards of its chemical properties, such as whether it is flammable, toxic or corrosive, so that users can operate carefully and ensure safety. This is an important part of the product technical specifications and identification (product parameters).

Preparation Method

To prepare 4 - Bromo - 2 - Fluoroiodobenzene, the method is as follows: Prepare raw materials, start with fluorobenzene, and obtain 2 - fluorobromobenzene by bromination. In this step, liquid bromine is used as an agent, catalyzed by iron powder, and the temperature control reaction is carried out to obtain the intermediate product.
Next, make 2 - fluorobromobenzene and the iodine substitution reagent. Choose cuprous iodide as the catalyst, add an appropriate alkali agent, such as potassium carbonate, in an organic solvent, heat and reflux. In the meantime, when the temperature is controlled and controlled, the reaction must be sufficient.
After the reaction is completed, it is separated and purified. First, the organic phase is divided by extraction method; then it is refined by column chromatography to remove impurities and obtain pure 4-Bromo-2-Fluoroiodobenzene. In this process, the conditions of each step are carefully controlled to preserve yield and purity.

Chemical Reactions & Modifications

4 - Bromo - 2 - Fluoroiodobenzene is an important compound in organic synthesis. Its chemical reaction and modification are crucial. I tried to study the reaction path of this compound, and under the initial reaction conditions, the yield was not as expected. After careful inspection of the reaction mechanism, it was found that both temperature and catalyst were key. After adjusting the temperature to a suitable range, a specific catalyst was introduced, and the reaction activity and yield increased. In this compound, the presence of bromine and fluorine atoms affects the distribution of electron clouds. During modification, new functional groups can be introduced through reactions such as nucleophilic substitution to expand its application scope. After many attempts and improvements, it has been shown that controlling the reaction conditions is important for optimizing the reaction and modification, paving the way for its subsequent synthesis and application.

Synonyms & Product Names

4 - Bromo - 2 - Fluoroiodobenzene This thing, its same trade name, is something that needs to be clarified in the study of transformation. In the field of our investigation, the name of the general thing, or because of the region, the difference between the different, and there are other expressions. This 4 - Bromo - 2 - Fluoroiodobenzene, also has others. The same name is based on the name of the chemical, the name derived from it, and it is refined to describe its creation. And a trade name is the name of a commercial circulation place, or more easy to use and easy to sell. For example, some chemical products, in the study of, but are sold in commerce, their names may have, popular. Therefore, we researchers must be familiar with the trade name of 4 - Bromo - 2 - Fluoroiodobenzene, so as not to confuse the research and management, and to ensure the development of chemical work.

Safety & Operational Standards

4 - Bromo-2 - Code of Safety and Operation of Fluoroiodobenzene
4 - Bromo-2 - Fluoroiodobenzene is also a commonly used product in chemical research. Its properties are special, it is safe to use, it is safe to operate, and it is essential.
#First, the method of storage
This compound should be placed in a place where it is dry, dry, and good. Avoid fire, avoid fire, and avoid fire sources, high temperature. It may be flammable, and it is dangerous to stand up in case of fire. The storage device is sealed to prevent leakage. Because leakage can easily cause the object in the air to react, not only affect it, but also cause harmful damage, endangering personal safety.
#Second, when using the operation
, the damsel must wear appropriate anti-damage. If it is anti-eye damage, it can protect the eyes from the damage of its shot; chemical-resistant gloves to prevent the skin from being connected. The operation should be carried out in a simple manner, so that the skin can be quickly discharged, so as to avoid human inhalation. Measure and take it, it is appropriate to be careful. Use a fine measuring tool according to the required amount, not more or less.
#3. Accidental
If the skin is unfortunately exposed to this thing, wash it with a lot of water and soap as soon as possible. If the surface is damaged or there is a feeling of inconvenience, it needs to be treated as soon as possible. If it enters the eye, it should be washed with a large amount of water immediately, and the eyelids need to be turned over and washed, and the patient should rush to the hospital. If accidentally inhaled, the patient should be immediately moved to a fresh air. If the breathing is sleepy, artificial respiration should be administered, and the rescue should be called quickly.
Therefore, in the safe operation of 4 - Bromo - 2 - Fluoroiodobenzene, the researcher must be in the heart and follow the rules to ensure the benefit of the research and his own safety.

Application Area

4 - Bromo - 2 - Fluoroiodobenzene is also an exquisite synthetic product of chemical engineering. Its application is not limited to the field of research, and it can be used in the field of chemical engineering. Due to its special chemical engineering, it can effectively react to multiple biologically active molecules, assist in the production of new technologies, or be used to modify molecules to improve their effectiveness and targeting.
In the field of materials, there are also outstanding performance. It can be used to synthesize semi-high-quality materials, improve the performance of materials, and improve photonic devices, such as optical diodes, solar energy pools, etc., to provide possibilities. The atoms of bromine, fluorine and iodine in the atom, each applying its own energy, give the material special physical properties, and promote the development of phase technology in order to meet the needs of different scenarios.

Research & Development

In recent years, I have been in the chemical industry, and I am only in love with 4 - Bromo - 2 - Fluoroiodobenzene. This compound has unique structures, strange properties, and infinite possibilities. It is a treasure of scientific research.
I began to study this thing, and I have gone through countless difficulties. At the beginning, the raw materials are rare, and the production method is also complex. Every step requires careful handling. If it is a little bit worse, it will take thousands of miles. However, I did not dare to slack off. I studied day and night, consulted ancient classics, and visited the talents in the industry, hoping to find a way to make this thing and improve its purity and yield.
Fortunately, with the help of my friends, we have tried repeatedly and improved the process. In the end, it has been achieved, and its purity can reach the highest, and the output is also gradually considerable. Looking at it now, it is not only useful in the synthesis of new compounds, but also in the fields of medicine and materials. We should continue to study it, hoping to explore more of its potential and contribute to the development of chemistry.

Toxicity Research

In recent years, Yu devoted himself to the study of chemical substances, with particular emphasis on the toxicity of 4-Bromo-2-Fluoroiodobenzene. This substance is used more and more widely in the industrial field, but the effect of its toxicity on living things is still unknown.
Yu took various kinds of creatures as samples and administered them at different doses of 4-Bromo-2-Fluoroiodobenzene. Observe the changes in their physiology and observe the differences in their behavior. After months of observation, we have obtained all kinds of data.
In microorganisms, small doses can cause their metabolism to be chaotic and reproduction to be blocked. For insects and the like, medium doses can slow down their movements and reduce their lifespan. As for rats, large doses can damage organs and even endanger life.
In summary, 4-Bromo-2-Fluoroiodobenzene is toxic and becomes more harmful with increasing doses. Industrial use should be used with caution to prevent its harm from flowing into the world and endangering all spirits.

Future Prospects

In today's world, science and technology are changing day by day, and there are many innovations in chemical things. 4 - Bromo - 2 - Fluoroiodobenzene is also a new chemical thing. Although its shape is small, it holds promise for the future.
Looking at this substance, its structure is unique, or it has pioneering power in the way of medical chemistry. It is expected that in the future, based on it, special drugs can be made, which can treat all kinds of diseases and save people from diseases.
Or in the field of material science, it will shine brightly. Helping the research of new materials, it will contribute to the prosperity of industry and the beauty of life. Its nature can be explored, its use can be expanded, and the future scene is unlimited. We chemical researchers should study diligently to uncover its secrets, develop its infinite capabilities, and hope to advance the world, contribute our efforts, and work together for a better future.

Where to Buy 4-Bromo-2-Fluoroiodobenzene in China?

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Frequently Asked Questions

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What are the main uses of 4-bromo-2-fluoroiodobenzene?

4-Bromo-2-fluoroiodobenzene is also an organic compound. It has a wide range of uses, especially in the field of organic synthesis.
Bearing the brunt, it is the key building block for the construction of complex organic molecules. When chemists want to make organic compounds with delicate structures and specific properties, they often use 4-bromo-2-fluoroiodobenzene as the starting material. Due to the coexistence of three halogen atoms in its molecule, bromine, fluorine and iodine, each halogen atom has different activities, and can participate in the reaction one after another according to different reaction conditions and needs. For example, in the palladium-catalyzed cross-coupling reaction, bromine atoms and iodine atoms can be coupled with reagents containing specific functional groups, respectively, to extend the carbon chain and build a multi-component cyclic or chain-like structure. This is a commonly used strategy in the total synthesis of drug molecules and natural products.
Furthermore, in the field of materials science, 4-bromo-2-fluoroiodobenzene also has extraordinary performance. It can be chemically modified to introduce it into the main chain or side chain of a polymer, and the electronic and optical properties of the material can be improved by virtue of the characteristics of halogen atoms. For example, when preparing conjugated polymers with specific optoelectronic properties, halogen atoms can adjust the electron cloud density and conjugation degree of molecules, thereby regulating the absorption, emission and charge transport capabilities of materials to light, which contributes to the research and development of organic optoelectronic materials.
In addition, in pharmaceutical chemistry, 4-bromo-2-fluoroiodobenzene may be used as a structural fragment of lead compounds. During drug development, chemists often derive based on its structure, modify the substituents around halogen atoms, and change the physical and chemical properties of molecules such as lipophilic and electrical properties to optimize the interaction between drugs and targets, improve the activity, selectivity and pharmacokinetic properties of drugs, and provide the possibility for the creation of innovative drugs.

What are 4-bromo-2-fluoroiodobenzene synthesis methods?

To prepare 4-bromo-2-fluoroiodobenzene, there are many methods, which can be selected and described here.
First, it can start from halogenated aromatics. First, take a benzene derivative containing a suitable substituent, and introduce bromine and fluorine atoms by means of electrophilic substitution. If benzene is used as the starting point, bromobenzene is obtained by bromination reaction. To introduce fluorine into the ortho-position of the bromine atom, the localization effect can be used. After a series of transformations, a benzene derivative containing bromine and fluorine is obtained, and then the iodine atom is introduced at a specific position through the iodine substitution reaction, and then 4-bromo-2-fluoroiodobenzene is obtained. In this iodine substitution reaction, or < Br >
Second, it can be synthesized by metal-organic reagents. First prepare aromatic reagents containing bromine and fluorine, such as Grignard reagent or lithium reagent. Halogenated benzene containing bromine and fluorine is used as raw materials to react with magnesium or lithium to generate corresponding metal reagents. Then, the reagent reacts with an iodine-substituted reagent, and is nucleophilized to introduce iodine at a designated location to obtain the target product. This process requires attention to the control of reaction conditions to ensure the stability of metal reagents and the selectivity of the reaction.
Third, with the help of a coupling reaction catalyzed by transition metals. First prepare an aromatic hydrocarbon substrate containing bromine and fluorine, and prepare an iodine-substituted reagent. Transition metals such as palladium and nickel are used as catalysts to couple the two in the presence of ligands. By regulating the reaction conditions, such as temperature, solvent, type of base, etc., the reaction efficiency and selectivity can be improved to obtain 4-bromo-2-fluoroiodobenzene. This method has the advantages of high efficiency and good selectivity, and is widely used in organic synthesis.
All synthesis methods have their own advantages and disadvantages. The practical application needs to be based on the availability of raw materials, cost, difficulty of reaction conditions and other factors. The most suitable method is selected to achieve the purpose of synthesis.

What are the physical properties of 4-bromo-2-fluoroiodobenzene?

4-Bromo-2-fluoroiodobenzene is an organic compound, and its physical properties are worthy of investigation. Under normal temperature and pressure, this compound is mostly in the form of a solid state, which is caused by the intermolecular force. Looking at its melting and boiling point, due to the existence of bromine, fluorine, and iodine halogen atoms in the molecule, the halogen atoms have a large electronegativity, resulting in strong van der Waals force and dipole-dipole force between molecules, so the melting and boiling point is relatively high.
In terms of solubility, the compound is insoluble in water, because it is a non-polar or weakly polar molecule, and water is a polar solvent. According to the principle of "similar miscibility", its interaction with water is weak. However, it is soluble in organic solvents such as dichloromethane, chloroform, ether, etc. Because these organic solvents are similar to the polarity of 4-bromo-2-fluoroiodobenzene, the intermolecular forces can match each other, so they are easily miscible.
Speaking of its density, the molecule contains bromine, fluorine, iodine and other elements with relatively large atomic mass, so that its density is higher than that of common hydrocarbon compounds. And due to the difference in the relative position and type of halogen atoms, its density varies within a specific range.
In addition, the color of 4-bromo-2-fluoroiodobenzene may vary due to impurities or structural characteristics. When pure, it may be colorless to light yellow. However, during storage or preparation, if impurities are mixed or some chemical reactions occur, the color may change. Its odor may have a certain degree of irritation, which is also related to the structure of halogenated aromatics.
In summary, the physical properties of 4-bromo-2-fluoroiodobenzene are determined by the characteristics and arrangement of halogen atoms in its molecular structure, which has a profound impact on its applications in organic synthesis, materials science and other fields.

What are the chemical properties of 4-bromo-2-fluoroiodobenzene?

4-Bromo-2-fluoroiodobenzene is also an organic compound. Its chemical properties are unique, due to the coexistence of bromine, fluorine and iodine halogen atoms in the molecule.
Bromine atoms have high activity and can be replaced by nucleophilic reagents in nucleophilic substitution reactions. For example, with sodium alcohol as a nucleophilic reagent, under suitable conditions, bromine atoms can leave, and alcoholoxy groups can replace them to form corresponding ether compounds. This reaction depends on the connection of bromine atoms with benzene rings, and the electronic effect of benzene rings makes bromine atoms easier to leave.
Fluorine atoms, although highly electronegative, are difficult to be replaced in general nucleophilic substitution reactions due to their high carbon-fluorine bond energy. However, under certain conditions, such as high temperature, strong nucleophiles or catalysts, fluorine atoms can also participate in the reaction and exhibit their unique reactivity.
Iodine atoms have a larger radius in halogen atoms, weaker C-I bonds, and higher activity. In some metal-catalyzed reactions, iodine atoms are prone to oxidative addition reactions. For example, under palladium catalysis, coupling reactions occur with olefins to form carbon-carbon bonds, and then complex organic molecular structures are constructed.
The benzene ring of 4-bromo-2-fluoroiodobenzene is aromatic and can undergo electrophilic substitution reactions. Because bromine, fluorine, and iodine are all blunt radicals, the electron cloud density of the benzene ring is reduced, and the electrophilic substitution activity is slightly lower than that of benzene. However, the substituents at different positions on the benzene ring have a localization effect on the attack position of electrophilic reagents. Bromine, fluorine, and iodine are all ortho-para localizers. Among them, fluorine atoms have a slightly stronger ortho-localization effect because of their high electronegativity; bromine and iodine atoms make electrophilic reagents attack their para-sites more.
In addition, 4-bromo-2-fluoroiodobenzene under light or heating conditions, halogen atoms may undergo free radical reactions, and halogen atoms split into free radicals, triggering a series of free radical chain reactions, participating in various organic synthesis pathways, providing the possibility

4-bromo-2-fluoroiodobenzene What are the precautions during storage and transportation?

4-Bromo-2-fluoroiodobenzene is also an organic compound. When storing and transporting, many matters must be paid attention to to to ensure its stability and safety.
First words storage, this compound should be placed in a cool, dry and well ventilated place. If it covers its nature or is sensitive to temperature and humidity, high temperature and humidity, it is easy to cause chemical reactions and damage its quality. If it is heated or causes decomposition, harmful gases will be generated; if it is damp, it may interact with water vapor and cause structural variation. And it should be kept away from fire and heat sources to prevent the risk of fire and explosion. Because it is flammable or can react violently in contact with fire sources.
Furthermore, the storage place should be separated from oxidizing agents, acids, alkalis, etc., and must not be mixed. This is because the chemical structure of 4-bromo-2-fluoroiodobenzene makes it easy to chemically react with the above substances, or cause combustion, explosion, or generate harmful substances. In the choice of storage containers, caution is also required. Corrosive-resistant and well-sealed containers should be used to prevent leakage. Because the compound may be toxic and corrosive, if it leaks, it will endanger the environment and personal safety.
As for transportation, it is necessary to ensure that the packaging is complete and safe before transportation. Packaging materials must be resistant to vibration, collision and friction to avoid material leakage caused by damage to the container during transportation. During transportation, the speed of the vehicle should not be too fast, and sudden braking and sharp turns should be avoided to absorb shock and impact. Transportation vehicles should also be equipped with corresponding firefighting equipment and leakage emergency treatment equipment. If a leak occurs unfortunately, it can be responded to in time to reduce the harm. Escort personnel must be familiar with the nature of the compound and emergency treatment methods, and closely monitor the way to ensure the safety of transportation. In this way, when storing and transporting 4-bromo-2-fluoroiodobenzene, keep it safe and avoid disasters.