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What are the chemical properties of 4-chloro-3-iodo-1h-pyrrolo [2,3-b] pyridine
4-Chloro-3-iodine-1H-pyrrolido [2,3-b] pyridine, this is an organic compound. Its chemical properties are unique and it is composed of many properties.
First of all, its structure contains a pyrrolido-pyridine core skeleton, and the chlorine atom and the iodine atom are connected to specific positions. This structure gives it specific chemical activity. Because both chlorine and iodine are halogen elements, they have certain electronegativity, which makes the molecule polar, which has a profound impact on its physical and chemical properties.
In terms of chemical reactivity, halogen atoms can participate in many reactions. Chlorine and iodine atoms can undergo nucleophilic substitution reactions. When suitable nucleophilic reagents are encountered, halogen atoms can be replaced, and various derivatives can be derived. This property brings many possibilities for organic synthesis, which can be used to construct more complex compound structures.
At the same time, in view of the nitrogen heterocycle of the compound, the nitrogen atom has a lone pair of electrons, which can exhibit alkalinity and react with acids to form salts. This property is of great significance in the field of medicinal chemistry, because it may be used to improve the solubility and stability of drugs.
From the perspective of stability, due to the presence of halogen atoms, the stability of the compound is affected or affected under certain conditions. The carbon-halogen bond of the halogen atom may break under specific reagents or conditions, triggering a chemical reaction. However, under normal conditions, without special reagents or environmental stimuli, the compound is relatively stable.
In addition, its electronic structure also affects its spectral properties. In ultraviolet-visible spectroscopy, or due to the presence of conjugated systems, specific absorption peaks appear, which can be used for qualitative and quantitative analysis of compounds. In infrared spectroscopy, vibration absorption peaks of different chemical bonds can help determine the existence of each functional group in the molecule.
In summary, 4-chloro-3-iodine-1H-pyrrolido [2,3-b] pyridine exhibits diverse chemical properties due to its special structure, and has important potential value in organic synthesis, medicinal chemistry and analytical chemistry.
What are the main uses of 4-chloro-3-iodo-1h-pyrrolo [2,3-b] pyridine
4-Chloro-3-iodine-1H-pyrrolido [2,3-b] pyridine is one of the organic compounds. It has a wide range of uses in the field of medicinal chemistry and is often a key intermediate in the synthesis of various drugs. Due to the special chemical structure of this compound, it can endow the prepared drug with unique physiological activities and pharmacological properties. For example, it can be used to create anti-cancer drugs with specific targeting, and by the precise action of its structure and specific targets of cancer cells, it can inhibit the proliferation of cancer cells and induce their apoptosis.
In the field of materials science, 4-chloro-3-iodine-1H-pyrrolido [2,3-b] pyridine also shows potential applications. Or it can participate in the preparation of organic materials with special photoelectric properties for organic Light Emitting Diode (OLED), organic solar cells and other devices. Due to its structure, it is expected to improve the performance of such devices, such as improving luminous efficiency and enhancing photoelectric conversion efficiency.
Furthermore, in the field of pesticide chemistry, this compound may be used as a raw material for the synthesis of new pesticides. Through appropriate chemical modification, pesticide products with high killing effect on specific pests, environmentally friendly and low toxicity are created to meet the needs of modern agriculture for green and efficient pesticides. In short, 4-chloro-3-iodine-1H-pyrrolido [2,3-b] pyridine has important uses in many important fields, providing a key chemical basis for the development of related fields.
What is the synthesis method of 4-chloro-3-iodo-1h-pyrrolo [2,3-b] pyridine
The synthesis of 4-chloro-3-iodine-1H-pyrrolido [2,3-b] pyridine is an important topic in organic synthetic chemistry. To obtain this compound, it can be achieved through a multi-step reaction.
The selection of starting materials is crucial, often starting with pyridine or pyrrole derivatives with appropriate substituents. One method can first introduce a halogen atom at a specific position on the pyridine ring using a pyridine derivative as a base. For example, an electrophilic substitution reaction can be used to react pyridine with an appropriate halogenating agent. If you want to introduce chlorine atoms, you can choose chlorine-containing reagents, such as thionyl chloride, etc., under suitable reaction conditions, so that chlorine atoms replace specific hydrogen atoms on the pyridine ring to form chlorine-containing pyridine derivatives.
Thereafter, for the construction of pyrrole rings. Nitrogen-containing and carbon-containing reagents can be used to form cyclization. For example, with appropriate amines and halogenated hydrocarbon derivatives, under the catalysis of bases, condensation reactions are carried out to construct pyrrole rings. In this process, precise control of reaction conditions, such as temperature, solvent and amount of base, is required to ensure that the reaction proceeds in the direction of generating the target pyrrolido-pyridine structure.
After the basic skeleton of pyrrolido-pyridine is formed, iodine atoms are introduced. In this step, the iodine substitution reaction can be used to select suitable iodizing reagents, such as iodine elemental substance and appropriate oxidant combination, to introduce iodine atoms at specific positions in the pyridine ring, and finally 4-chloro-3-iodine-1H-pyrrolido [2,3-b] pyridine is generated.
Each step of the reaction requires the separation and purification of the product. The commonly used methods include column chromatography, recrystallization, etc., to ensure the purity of the product and meet the needs of subsequent research or application. In this way, through multiple delicate reaction steps, the target compound can be obtained.
What is the price range of 4-chloro-3-iodo-1h-pyrrolo [2,3-b] pyridine in the market?
4-Chloro-3-iodine-1H-pyrrolido [2,3-b] pyridine, this is an organic compound, but in the market price range, there is no fixed number, and its price depends on many reasons.
First, the purity of this product is the key. If the purity is extremely high, it is almost pure, suitable for high-end scientific research experiments, and its price is high; if the purity is slightly lower, it is only used for general experiments, and the price may be slightly reduced. For example, if the purity is above 99%, it is used for precision medicine research and development, and its price is far higher than that of 95% purity.
Second, the difficulty of preparation also affects the price. If the preparation requires complicated steps, harsh conditions, and expensive reagents, the cost will increase significantly and the price will be high. This compound contains chlorine and iodine, and the synthesis may require special technologies and materials, resulting in higher costs.
Furthermore, the market supply and demand situation affects its price. If the demand is strong, such as pharmaceutical companies buying in large quantities, but the supply is limited, the price will rise; if the market demand is weak and the supply is sufficient, the price may decline.
In addition, different suppliers have different prices. Large and well-known suppliers have high prices due to their good reputation and stable product quality; small suppliers compete for the market or price lower.
Due to the interaction of the above factors, the price of 4-chloro-3-iodine-1H-pyrrole [2,3-b] pyridine is difficult to specify, or ranges from tens to thousands of yuan per gram. For the exact price, please consult chemical raw material suppliers and reagent sales platforms to obtain accurate quotations.
What are the manufacturers of 4-chloro-3-iodo-1h-pyrrolo [2,3-b] pyridine
4-Chloro-3-iodine-1H-pyrrolido [2,3-b] pyridine is an organic compound, which is widely used in the fields of medicinal chemistry and organic synthesis. However, its manufacturer is rarely mentioned in the ancient texts of our country, and it is now known to the world.
In today's world, there are many chemical companies and scientific research institutions involved in the production of such compounds. Such as XX Chemical Co., Ltd., which has been focusing on the field of organic synthetic chemistry for a long time, with advanced technology and equipment, it has deep attainments in the production of fine chemicals, or can produce this substance. Furthermore, the scientific research teams of some universities will also synthesize 4-chloro-3-iodine-1H-pyrrolido [2,3-b] pyridine by themselves due to scientific research needs.
There are also many such manufacturers abroad. Some large chemical companies in Europe, America and other countries have strong R & D and production capabilities, and are in a leading position in the production of high-end organic compounds, some of which may involve producers of this substance.
However, if you want to know the detailed list of manufacturers, you need to search carefully in the chemical product information platform and professional chemical literature database, or you can get more accurate and comprehensive information. The manufacturer of this compound may change due to changing times and market demand, and real-time information shall prevail.