4 Chloro 3 Iodo 2 3 Dihydro 1h Pyrrolo 2 3 B Pyridine
Iodobenzene

4-chloro-3-iodo-2,3-dihydro-1h-pyrrolo[2,3-b]pyridine

Fengxi Chemical

Specifications

HS Code

909771

Chemical Formula C7H6ClIN2
Molar Mass 296.49 g/mol
Appearance Solid (predicted, actual may vary)
Melting Point Unknown
Boiling Point Unknown
Solubility In Water Low (due to non - polar nature of aromatic rings, predicted)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform (predicted)
Density Unknown
Pka Unknown
Stability Sensitive to light and air (due to presence of iodine, predicted)
Chemical Formula C7H6ClIN2
Molecular Weight 296.49
Appearance Solid (usually)
Solubility In Water Low (expected due to its non - polar nature)
Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
Stability Stable under normal conditions; may react with strong oxidizing agents
Chemical Formula C7H6ClIN2
Molecular Weight 296.49
Appearance Solid (predicted)
Solubility Insoluble in water (predicted)
Logp 2.76 (predicted)
Name 4-chloro-3-iodo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine
Molecular Formula C7H6ClIN2
Molecular Weight 280.5
Appearance Solid (predicted)
Boiling Point Predicted around 370 - 380 °C
Melting Point Predicted range: 100 - 120 °C
Solubility Slightly soluble in water, more soluble in organic solvents like DMSO, DMF
Pka Predicted to have a pKa in the range related to pyridine - like nitrogen basicity, around 4 - 6
Logp Predicted to have a logP value around 2 - 3, indicating moderate lipophilicity
Density Predicted density around 2.0 - 2.2 g/cm³
Packing & Storage
Packing 500g of 4 - chloro - 3 - iodo - 2,3 - dihydro - 1H - pyrrolo[2,3 - b]pyridine in sealed chemical - grade bags.
Storage 4 - chloro - 3 - iodo - 2,3 - dihydro - 1H - pyrrolo[2,3 - b]pyridine should be stored in a cool, dry place away from direct sunlight. Keep it in a tightly sealed container to prevent moisture and air exposure, which could potentially cause degradation. Store it separately from incompatible substances, in a well - ventilated area designated for chemicals to ensure safety.
Shipping 4 - chloro - 3 - iodo - 2,3 - dihydro - 1H - pyrrolo[2,3 - b]pyridine is shipped in properly sealed containers. It adheres to chemical transport regulations, ensuring safe transit from source to destination, protected from environmental factors.
Free Quote

For samples, pricing, or more information, please call us at +8615371019725 or mail to info@bouling-chem.com.

We will respond to you as soon as possible.

Tel: +8615371019725

Email: info@bouling-chem.com

4-chloro-3-iodo-2,3-dihydro-1h-pyrrolo[2,3-b]pyridine 4-chloro-3-iodo-2,3-dihydro-1h-pyrrolo[2,3-b]pyridine 4-chloro-3-iodo-2,3-dihydro-1h-pyrrolo[2,3-b]pyridine
General Information
Frequently Asked Questions
What are the physical properties of 4-chloro-3-iodo-2,3-dihydro-1h-pyrrolo [2,3-b] pyridine
The physical properties of 4-chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine are crucial for many applications.
Looking at its appearance, under room temperature, or in the form of white to light yellow solid powder, the texture is fine and uniform, just like the micro-powder of nature. This appearance feature not only gives it a unique visual appearance, but also reflects the order of its microstructure to a certain extent.
The melting point has been determined by many researchers and is approximately in a specific temperature range. This melting point value is stable and accurate, just like a precise scale for measuring the transformation of its physical state, which is an inherent physical constant of the substance. The characteristics of melting point are not only due to the delicate balance of forces between molecules, but also influenced by the unique configuration of the molecular structure.
In terms of solubility, it shows different performances in common organic solvents. In some polar organic solvents, it can be moderately dissolved, just like a fish entering water, and the interaction between molecules prompts it to disperse. In non-polar solvents, the solubility is much inferior, just like the barrier between oil and water, and it is difficult to blend between molecules. This difference in solubility is due to the joint action of the polar characteristics of the molecules of the substance and the properties of the solvent molecules.
Furthermore, density is also an important characteristic of its physical properties. Its density value is accurate and unique, reflecting the mass distribution of matter per unit volume. This value does not exist in isolation, but is closely related to the crystal structure and molecular accumulation of matter, like threads of clues, connecting microscopic and macroscopic properties.
In summary, the physical properties of 4-chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine, such as appearance, melting point, solubility, density, etc., each carry information on the microstructure and molecular properties of the substance, just like a delicate picture, slowly unfolding its unique physical appearance, laying a solid foundation for subsequent research and application.
What are the chemical properties of 4-chloro-3-iodo-2,3-dihydro-1h-pyrrolo [2,3-b] pyridine
4-Chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine is an organic compound. Looking at its structure, it contains halogen atoms such as chlorine and iodine, and has the fused heterocyclic structure of pyrrolido pyridine. This structure gives it its unique chemical properties.
Because it contains chlorine and iodine halogen atoms, it can exhibit the characteristics of halogenated hydrocarbons. Halogen atoms are highly active and can participate in many nucleophilic substitution reactions. Under appropriate conditions, chlorine and iodine atoms can be replaced by other nucleophilic reagents, such as hydroxyl groups, amino groups, etc., to synthesize a variety of derivatives, which are widely used in the field of organic synthesis.
Furthermore, the pyrrolidine fused heterocyclic structure of the compound endows it with certain aromaticity and stability. The presence of nitrogen atoms in the heterocyclic structure enables it to provide lone pairs of electrons, which can participate in coordination reactions and form complexes with metal ions. It may have potential applications in the fields of materials science and catalysis.
Because of its multiple reaction check points, under different reaction conditions, it can selectively modify specific positions, providing the possibility for the synthesis of complex organic molecules. In pharmaceutical chemistry, it can be used as a lead compound to develop drugs with specific biological activities through structural modification and optimization. However, its specific chemical properties are also affected by reaction conditions, solvent environment and other reagents that react with it. The reaction activity and chemical behavior should be investigated in depth according to the specific experimental scenarios and purposes.
In which areas is 4-chloro-3-iodo-2,3-dihydro-1h-pyrrolo [2,3-b] pyridine used?
4-Chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine is useful in many fields such as medicine and materials.
In the field of medicine, due to its unique chemical structure, it can be used as a key intermediate to synthesize compounds with specific biological activities. If carefully designed and modified, it may generate drug molecules with high affinity and selectivity for specific disease targets, or can be used to develop anti-tumor drugs. The abnormal proliferation of tumor cells is closely related to a specific signaling pathway, and this compound may be able to inhibit the growth and spread of tumor cells by precisely acting on key proteins in this signaling pathway. For example, in the research and development of drugs for neurological diseases, it can modulate the transmission of neurotransmitters, which is helpful for the treatment of Parkinson's disease, Alzheimer's disease and other diseases.
In the field of materials, it can also show unique properties. In the field of organic optoelectronic materials, the specific electronic properties endowed by molecular structure can be applied to organic Light Emitting Diode (OLED). OLED is widely used in display technology. This compound may optimize the performance of OLED light-emitting layers, improve luminous efficiency and color purity, and make display screens appear more vivid and realistic colors. In the field of organic photovoltaic materials, it may participate in the construction of high-efficiency photoactive layers to improve the photoelectric conversion efficiency of solar cells, contributing to the development of renewable energy.
In addition, at the level of scientific research and exploration, this compound provides a rich research material for researchers in the fields of chemical synthesis and medicinal chemistry. Through various chemical modifications and derivatization reactions, the relationship between structure and activity can be deeply explored, laying a theoretical foundation for the creation of new functional compounds.
What is the synthesis method of 4-chloro-3-iodo-2,3-dihydro-1h-pyrrolo [2,3-b] pyridine
To prepare 4-chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine, the method is as follows:
First take an appropriate starting material, with a nitrogen-containing heterocyclic compound as the group, which may have the basic structure of pyrrolido-pyridine, and reserve a modifiable group at the corresponding position, such as the activity check point of the halogenation reaction.
The first step or halogenation reaction can be selected from suitable halogenating reagents, such as chlorine-containing reagents, such as sulfoxide chloride, phosphorus oxychloride and the like. Under appropriate reaction conditions, such as in a specific solvent system, such as non-protic solvents such as dichloromethane, N, N-dimethylformamide, etc., control the temperature and reaction time, so that the chlorine atom precisely replaces the hydrogen atom at the target position to obtain a chlorine-containing intermediate.
Next, iodine atoms are introduced into the intermediate. Select suitable iodizing reagents, such as the combination of iodine elemental and reducing agent, or iodine substitutes such as N-iodosuccinimide, etc. In another suitable reaction environment, the solvent can still be used as the above-mentioned aprotic solvent or slightly adjusted, the temperature and reaction time are adjusted, so that the iodine atom replaces the hydrogen at the predetermined position, and then 4-chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine is obtained.
After each step of the reaction, it is necessary to separate and purify the steps, such as column chromatography, recrystallization, etc., to remove the unreacted raw materials and by-products to obtain a pure target product. And the conditions of each step of the reaction need to be carefully adjusted, and the reaction parameters need to be optimized according to the characteristics of the raw materials and products to increase the yield and purity of the product.
What is the market outlook for 4-chloro-3-iodo-2,3-dihydro-1h-pyrrolo [2,3-b] pyridine
4-Chloro-3-iodine-2,3-dihydro-1H-pyrrolido [2,3-b] pyridine is an organic compound. Its market prospect is related to many aspects.
Looking at the field of medicine, this compound may have potential biological activity due to its unique structure. In the process of drug development, it may become a key intermediate. Today, there is a strong demand for new drug creation, and there is a great thirst for compounds with special activities. If it is confirmed by research that it can participate in the regulation of specific biological targets, or provide new opportunities for the development of anti-cancer, anti-infection drugs, etc., the market prospect is quite promising.
As for the field of materials science, with the rapid development of science and technology, the demand for functional materials is increasing. If this compound can exhibit unique optoelectronic properties, such as fluorescence properties, semiconductor properties, etc., it can be used to prepare organic Light Emitting Diode (OLED) materials, solar cell materials, etc. These emerging material markets are booming, and once its performance meets relevant application standards, it will open up a broad market space.
However, its market expansion also faces many challenges. Synthesis of this compound may pose technical difficulties, the cost remains high, and large-scale production is restricted. And the market competition is fierce, and it needs to compete with other similar compounds. To develop the market, it is necessary to study innovation in the synthesis process, reduce costs, and enhance product competitiveness.
In conclusion, the market outlook for 4-chloro-3-iodine-2,3-dihydro-1H-pyrrole [2,3-b] pyridine contains both opportunities and challenges. If the technical and cost difficulties can be overcome, it is expected to emerge in the fields of medicine and materials and gain a considerable market share.