4 Ethoxy 4 Iodobenzene
Iodobenzene

4-Ethoxy-4-Iodobenzene

Fengxi Chemical

Specifications

HS Code

209725

Chemical Formula C8H9IO
Molecular Weight 264.06
Appearance Solid
Melting Point 46 - 50 °C
Boiling Point 269.9 °C at 760 mmHg
Density 1.634 g/cm³
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Flash Point 116.0 °C
Cas Number 33508 - 36 - 8
Purity Typically high - purity grades available, e.g., 95%+

As an accredited 4-Ethoxy-4-Iodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 4 - ethoxy - 4 - iodobenzene packaged in a sealed, labeled glass bottle.
Storage 4 - ethoxy - 4 - iodobenzene should be stored in a cool, dry, well - ventilated area. Keep it away from heat sources, flames, and oxidizing agents. Store in a tightly sealed container to prevent moisture absorption and evaporation. Since it is a chemical, label the storage container clearly for easy identification and to ensure proper handling.
Shipping 4 - ethoxy - 4 - iodobenzene is shipped in accordance with strict chemical transportation regulations. Packed securely in appropriate containers to prevent leakage, it is transported by carriers licensed for hazardous chemicals.
Free Quote

Competitive 4-Ethoxy-4-Iodobenzene prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@bouling-chem.com.

We will respond to you as soon as possible.

Tel: +8615371019725

Email: sales7@bouling-chem.com

4-Ethoxy-4-Iodobenzene
General Information
Historical Development
4-Ethoxy-4-iodobenzene is also an organic compound. Its origin originated in the gradual pursuit of chemical research. At the beginning, the sages reached the field of organic chemistry and devoted themselves to exploring the properties and changes of various substances.
At that time, scholars studied the method of combining halogenated aromatics with ethers. After repeated experiments, with precise operation and careful measurement, this 4-ethoxy-4-iodobenzene was obtained. The method of its preparation has gradually become complete with the passage of time, from crude to exquisite.
The simple equipment and ignorance of cognition in the past have gradually been replaced by sophisticated equipment and profound learning. In the process of synthesis, chemists study the mechanism of the reaction and optimize the conditions, so that the yield of 4-ethoxy-4-iodobenzene rises and the purity increases. Looking at its development process is the trace of scientific evolution and accumulation of wisdom, which lays a solid foundation for the great cause of organic synthesis in later generations.
Product Overview
4-Ethoxy-4-Iodobenzene is an organic compound. Its shape and color are colorless to pale yellow liquids at room temperature, with a special odor. In this compound, the benzene ring is a group, with an ethoxy group at one end and an iodine atom at the other end. The ethoxy group is an organic group, which has a certain electronic effect and affects the properties of the molecule. The iodine atom is active and can be used as a leaving group in many chemical reactions to participate in substitution and other reactions. The preparation method is obtained by a series of reactions such as halogenation and etherification of benzene derivatives. In the field of organic synthesis, 4-Ethoxy-4-Iodobenzene is often an important intermediary, which can be used to prepare a variety of organic materials with special structures and properties, and has potential applications in pharmaceutical chemistry and other fields. It is an important object of organic chemistry research.
Physical & Chemical Properties
4-Ethoxy-4-Iodobenzene is an organic compound. Its physicochemical properties are particularly important. Looking at its physical properties, at room temperature, this substance may be in a solid state, with a specific melting point and boiling point. The melting point is the temperature limit at which a substance changes from a solid state to a liquid state. The melting point of this compound may vary depending on intermolecular forces. The boiling point is related to its gasification temperature.
In terms of its chemical properties, the structure of the benzene ring endows it with aromatic properties and can participate in many electrophilic substitution reactions. The ethoxy group at 4 positions is the power supply radical, which can affect the density distribution of the electron cloud of the benzene ring, so that the density of the electron cloud in the adjacent para-position increases, and it is easier to react with electrophilic reagents. Although the 4-position iodine atom has a certain electronegativity, it can also undergo substitution reactions under suitable conditions, showing its unique chemical activity. All these physicochemical properties are of great significance in organic synthesis and related fields.
Technical Specifications & Labeling
4-Ethoxy-4-Iodobenzene is an important organic compound. Its preparation process requires strict adherence to specific technical specifications and standards. During the preparation process, the selection and ratio of raw materials are crucial, and precise control of reaction conditions, such as temperature, pressure, reaction time and other parameters, can ensure the purity and yield of the product.
To identify this product, a series of criteria are required. Looking at its appearance, it should have a specific color state. Using spectroscopic analysis methods, such as infrared spectroscopy, nuclear magnetic resonance spectroscopy, etc., its molecular structure can be confirmed. According to the characteristic peak of the spectrum, it is determined whether it conforms to the structural characteristics of the product by comparing the standard map. The determination of physical constants such as melting point and boiling point is also an important identification method. Compared with the standard value, the purity of 4-Ethoxy-4-Iodobenzene products can be guaranteed by strictly controlling the technical specifications and identification standards.
Preparation Method
To make 4-Ethoxy-4-Iodobenzene, it is necessary to explain the raw materials and production process. The raw materials are selected, when benzene is used as a base, supplemented by ethanol, iodine, etc. The production process first reacts benzene with ethanol to obtain ethoxylbenzene. This step requires sulfuric acid as a catalyst and temperature control of about one hundred and twenty degrees. After a few times, the reaction is complete.
The reaction of ethoxylbenzene and iodine under specific conditions is obtained. This reaction is assisted by potassium iodide, adding an oxidant, such as hydrogen peroxide, and stirring at room temperature. After a few hours, the product can be seen to form.
Reaction step, prepare the utensils first, wash and dry. Take an appropriate amount of benzene and ethanol, put it into the reactor, add sulfuric acid, and react at temperature. After finishing, cool, and separate the liquid to take the organic phase. Then put the organic phase into another kettle, add potassium iodide, iodine and hydrogen peroxide, and stir the reaction.
As for the catalytic mechanism, sulfuric acid promotes the electrophilic substitution of benzene and ethanol in the first step, lowering the reaction energy barrier. Potassium iodide helps iodine to activate in the second step, making the reaction easier. In this way, 4-Ethoxy-4-Iodobenzene can be obtained.
Chemical Reactions & Modifications
In recent years, more attention has been paid to the reaction and modification of 4-Ethoxy-4-Iodobenzene. The reaction of this substance is related to many fields of chemical industry, and it is the key.
At the beginning, although the conventional method can cause the reaction, the yield is not ideal, and the purity of the product is also lacking. In order to improve, many books and methods have been collected to try to catalyze this reaction with different conditions and different reagents.
Or change the temperature, or change the pressure strength, or the type of catalyst. After repeated tests, some gains have been made. With the addition of a new type of catalyst, the temperature is controlled to an appropriate degree, and the pressure is adjusted to an appropriate environment, the reaction rate is significantly improved, the yield is also greatly increased, and the product purity is also considerable.
This is the effect of modification, and it also gives us a deeper understanding of the reaction of 4-Ethoxy-4-Iodobenzene, hoping to be able to widely apply it in chemical practice and promote the development of this field.
Synonyms & Product Names
The same trade name as 4-ethoxy-4-iodobenzene
There is currently a product named 4-ethoxy-4-iodobenzene. This product is relevant to the chemical field, but it also has the same trade name.
The same name is used to indicate the different uses of the same concept. The same name of 4-ethoxy-4-iodobenzene, or based on the description of its chemical properties, or according to its different properties. This is equivalent. Those who can help chemicals know this product from different angles and promote communication.
As for the trade name, it is often used in commercial activities. Merchants recognize the characteristics of their products, or facilitate market promotion, and provide a specific trade name for 4-ethoxy-4-iodobenzene. This trade name not only reflects the wisdom of the merchant, but also reflects the needs of the market.
, with the same trade name, all 4-ethoxy-4-iodobenzene are used in the market, so as to enrich our knowledge and use of this product.
Safety & Operational Standards
Safety and Handling Specifications for 4-ethoxy-4-iodobenzene
Fu 4-ethoxy-4-iodobenzene is an important substance in chemical research. During its experimental operation, many safety and operation specifications cannot be ignored.
The first word is safety. This substance may have certain chemical activity, and protection is the first priority when exposed. Experimenters wear suitable protective clothing, such as laboratory clothes, to prevent it from contaminating the body. And they need to wear protective gloves. The material should be able to resist the erosion of the substance and avoid direct contact with the skin. Eye protection is also indispensable. Goggles must be worn at all times to prevent substances from splashing into the eyes and causing eye damage.
Furthermore, the operating environment is very important. The experiment should be carried out in a well-ventilated place, so that the potentially volatile gas can be discharged in time to avoid accumulation in the experimental space and cause potential harm. If there is a substance spilled accidentally, do not panic, and clean it up according to the established process. First ensure your own safety, then use suitable materials to absorb, properly dispose of waste, and do not discard it at will to avoid polluting the environment.
In terms of operating specifications, when weighing, use precise instruments and take the amount required by the experiment. Do not take more waste or cause less experimental deviation. During the dissolution or reaction process, strictly control the temperature, time and other conditions. When heating, control the heat to prevent overheating from causing material decomposition or causing other accidents. The stirring process also needs to be uniform to make the reaction proceed evenly.
Also, the experimental records must be detailed. From the amount of raw materials, reaction conditions to experimental phenomena, all should be truthfully recorded for subsequent analysis and summary. Every step of operation must be done with caution and follow scientific methods, so as to ensure the safety of the experiment, so that the research of 4-ethoxy-4-iodobenzene can be carried out smoothly, and the intended purpose can be achieved, and the safety of the experimenter and the environment is also guaranteed.
Application Area
Today there is a substance called 4 - Ethoxy - 4 - Iodobenzene. This substance has its uses in many fields. In the field of medicine, it can be used as a key intermediate to help synthesize special drugs and heal chronic diseases. In materials science, it can participate in the preparation of new materials, endowing materials with specificity, such as optimizing their optical or electrical properties. Furthermore, in the field of fine chemicals, it can be used to create high-end fine chemicals, improve product quality and performance. It has a wide range of uses and adds to the development of many industries. It is as indispensable as a cornerstone in a high-rise building. It shows extraordinary potential in various application fields and promotes the continuous progress of related industries.
Research & Development
Today, there is a product called 4-Ethoxy-4-Iodobenzene, which is of great significance in our chemical research. We are committed to the research and development of this product.
At the beginning of the research, we carefully observed its physical properties, analyzed its structure, and understood its chemical properties. After various experiments, explore its reaction rules and seek the best synthesis method. Strive to increase its yield and improve its quality in an efficient and environmentally friendly way.
In the process of development, seek its wide use. Or it can be used for the preparation of new drugs, or to assist the progress of materials. Hope it can add bricks to the field of chemistry and promote the rise of science and technology. We must persevere and study unremittingly, and expect great success in the research and development of 4-Ethoxy-4-Iodobenzene.
Toxicity Research
Since modern times, chemical refinement, frequent emergence of new substances, 4 - Ethoxy - 4 - Iodobenzene, is also one of them. We take toxicological research as our service to observe the properties of this substance in detail.
At the beginning, observe its structure and think about its transformation in the body. Take all living beings as an experiment and observe their influence on this substance. Observe its eating, activities, and reproduction, all traces can be found.
After repeated tests, it was found that this substance may have potential toxicity. In some organisms, it can cause its physiological incompatibility, even endangering life. The signs of its poison are related to the ability of the organs, or disturb the metabolism, or disrupt the nerves.
However, in order to clarify the details, it still needs to be studied in depth. The nature of poisons is not known all the time, nor can it be observed everywhere. It is necessary to collect data and use all methods to understand the full picture of the toxicity of 4-Ethoxy-4-Iodobenzene for future generations, or to avoid its harm, or to make good use of it, all depend on current research.
Future Prospects
I have tried to study in the field of chemistry, and I have thought a lot about this product at 4-Ethoxy-4-Iodobenzene. Although I am temporarily on the road of research and exploration, I am looking forward to the future.
This product has unique properties and exquisite structure. It may be a key material in the process of organic synthesis. In the future, I hope it can shine in the industry of pharmaceutical creation. Or as a precursor to a good medicine for healing diseases, with its unique properties, it can break the dilemma of difficult diseases.
Also hope to emerge in the field of materials science. Based on it, develop exotic materials for use in the fields of electronics and optics, and help technology move forward. Although the road ahead is long, I firmly believe that with time, 4 - Ethoxy - 4 - Iodobenzene will be able to develop its potential, bring new images to the world, and achieve unfinished business.
Where to Buy 4-Ethoxy-4-Iodobenzene in China?
As a trusted 4-Ethoxy-4-Iodobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Ethoxy-4-Iodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-ethoxy-4-iodobenzene?
4-Ethoxy-4-iodobenzene is an important compound in organic chemistry. It has a wide range of uses and is reflected in many fields.
In the field of organic synthesis, it is often used as a key intermediate. With its unique structure, it can participate in a variety of chemical reactions, such as nucleophilic substitution reactions. Due to its high activity of iodine atoms, it is easily replaced by other nucleophilic reagents, thus assisting in the construction of complex organic molecular structures. By reacting with different nucleophilic reagents, various functional groups can be introduced to create conditions for the synthesis of organic compounds with specific functions, such as drug molecules, natural product analogs, etc.
In the field of materials science, 4-ethoxy-4-iodobenzene is also used. In the preparation process of some organic optoelectronic materials, it can be used as a starting material to synthesize materials with specific optoelectronic properties through a series of reactions. These materials have shown potential application value in the fields of organic Light Emitting Diode (OLED), organic solar cells, etc., which help to improve the performance of devices, such as enhancing luminous efficiency and improving energy conversion efficiency.
In the field of pharmaceutical chemistry, it can become an important foundation for drug research and development. After chemical modification and modification, it is possible to develop drug molecules with specific pharmacological activities. By introducing suitable functional groups into its structure, the interaction between drug molecules and biological targets can be adjusted, thereby achieving better therapeutic effects and providing a key foundation and possibility for new drug research and development.
In conclusion, 4-ethoxy-4-iodobenzene is of great significance to related scientific research and industrial production due to its important uses in organic synthesis, materials science and medicinal chemistry.
What are the physical properties of 4-ethoxy-4-iodobenzene?
4-Ethoxy-4-iodobenzene is also an organic compound. Its physical properties are many and can be described.
Under normal temperature, it is either a colorless to light yellow liquid or a crystalline solid, which varies depending on environmental conditions. Its color is elegant, mostly light color. This appearance can be observed by those who are new to this thing.
When it comes to melting point, the melting point of 4-ethoxy-4-iodobenzene is about within a specific range, but the exact value varies slightly depending on the preparation method and purity. At most moderate temperatures, this substance gradually melts from a solid state to a liquid state. The characteristics of this melting point are crucial for identification and purification.
The boiling point is also one of its important physical properties. Under atmospheric pressure conditions, the boiling point of 4-ethoxy-4-iodobenzene is in a certain range. When the temperature rises to the corresponding boiling point, the liquid boils and converts to a gaseous state. This boiling point data is an indispensable basis for the separation and purification of this compound.
In terms of solubility, 4-ethoxy-4-iodobenzene can exhibit good solubility in organic solvents such as ethanol and ether, but its solubility in water is poor. This property is due to the hydrophobicity of its molecular structure. The interaction between the molecules of the organic solvent and the molecules of 4-ethoxy-4-iodobenzene makes them easily miscible. The difference between the polarity of water and the molecular structure of the compound makes it difficult to dissolve in water.
For densities, 4-ethoxy-4-iodobenzene also has specific values. Its density may be different from that of water. This physical property can provide a basis for judgment and calculation when it involves actual operations such as mixing and separation.
In addition, the volatility of 4-ethoxy-4-iodobenzene is relatively moderate, neither extremely difficult nor highly volatile. Its vapor pressure has a corresponding value at a certain temperature. This vapor pressure is related to volatility and affects its diffusion and existence in the environment.
The physical properties of 4-ethoxy-4-iodobenzene are of great significance in the research of organic chemistry, chemical production and related fields.
What are 4-ethoxy-4-iodobenzene synthesis methods?
In the synthesis of 4-ethoxy-4-iodobenzene, benzene derivatives are often used as starting materials. One method is to take p-ethoxy aniline and make it react with sodium nitrite and hydrochloric acid at low temperature to undergo diazotization reaction to form diazonium salts. This diazonium salt is extremely unstable and needs to be mixed with potassium iodide solution immediately, and the diazonium group is then replaced by an iodine atom to obtain 4-ethoxy-4-iodobenzene.
There are also those who use p-ethoxy-anisole as the starting material. First, the methoxy group is oxidized to a carboxyl group with an appropriate strong oxidizing agent, such as potassium permanganate, to obtain p-ethoxy-benzoic acid. Subsequently, the acid interacts with phosphorus halide (such as phosphorus trichloride, phosphorus pentachloride, etc.) to convert the carboxyl group into an acid chloride. Then, the acid chloride is reduced to an aldehyde group by a reducing agent such as lithium aluminum hydride. Then, the aldehyde group and the hypohalous acid (such as hypoiodized acid) undergo a haloform reaction under basic conditions, and the aldehyde group is converted to a halogenated methyl group. Finally, the target product 4-ethoxy-4-iodobenzene can be obtained through hydrolysis and other steps.
Furthermore, the coupling reaction of p-ethoxy-phenylboronic acid with iodoaromatic hydrocarbons in an alkaline environment catalyzed by palladium is also an effective way to synthesize 4-ethoxy-4-iodobenzene. This reaction condition is relatively mild and has good selectivity, and is widely used in the field of organic synthesis. Through rational selection of reaction substrates, catalysts and reaction conditions, the target product can be efficiently obtained with less side reactions and high product purity.
What are the precautions in storage and transportation of 4-ethoxy-4-iodobenzene?
4-Ethoxy-4-iodobenzene is also an organic compound. During storage and transportation, many matters need to be paid attention to to ensure its stability and safety.
Primary storage environment. This compound should be stored in a cool, dry and well-ventilated place. Avoid heat and moisture to prevent it from deteriorating due to excessive temperature or humidity. High temperature can easily cause it to decompose, and humidity may cause chemical reactions and damage its quality.
Secondary and packaging materials. Choose suitable packaging materials to ensure that they are well sealed. Glass containers or specific plastic materials can effectively block air and moisture to prevent the compound from contacting with external substances. If the packaging is not good, air and moisture seep in, or the compound oxidizes or hydrolyzes.
When transporting, it should ensure that it is stable and prevent collision and vibration. Violent vibration or collision, or cause damage to the packaging, so that the compound leaks. The transportation process must follow relevant regulations and standards to ensure that the transporter is aware of its characteristics and emergency treatment methods.
Repeat to avoid mixing with incompatible substances. 4-ethoxy-4-iodobenzene may react with certain oxidizing agents, reducing agents, acids, bases, etc. Therefore, during storage and transportation, it must be isolated from such substances to prevent accidental chemical reactions.
Finally, the storage and transportation places should be equipped with corresponding emergency treatment equipment and materials. Such as adsorbents, to absorb in case of leakage; fire extinguishing equipment to respond to fire needs. And relevant personnel should be familiar with the emergency treatment process. In case of emergencies, they can be disposed of quickly and properly to reduce the hazard.
4-ethoxy-4-iodobenzene impact on the environment and human health
4-Ethoxy-4-iodobenzene is also an organic compound. However, its impact on the environment and human health should be carefully observed.
At the end of the environment, if 4-ethoxy-4-iodobenzene is released in nature, it may flow between soil and water. In the soil, or interact with various components in the soil, affecting the physical and chemical properties of the soil, or causing soil ecological imbalance, affecting the survival and reproduction of organisms in the soil. If it enters the water body, it will exist in the water for a long time due to its chemical properties or difficult to degrade, endangering aquatic organisms. Or cause damage to the physiological functions of fish, shellfish and other organisms, such as affecting their respiration, reproduction and other activities, or even reduce the population and destroy the balance of water ecology.
As for human health, 4-ethoxy-4-iodobenzene enters the human body through respiration, diet or skin contact. After entering the body, or interfere with normal biochemical reactions during metabolism in the body. Or affect the nervous system of the human body, causing dizziness, fatigue, memory loss, etc.; or involve the endocrine system, interfering with the normal secretion and regulation of hormones, thereby affecting human growth and development, reproductive function, etc. Long-term exposure to this substance may increase the risk of disease, such as carcinogenesis. Due to its structure or similarity to known carcinogens, it can lead to abnormal cell proliferation and differentiation, eventually leading to the formation of tumors.
In summary, although 4-ethoxy-4-iodobenzene may be useful in industrial or scientific research, its potential threat to the environment and human health should not be underestimated. It should be used with caution and effective prevention and control measures should be developed to reduce its harm.