4-Ethoxyiodobenzene, 4-Iodophenyl Ethyl Ether

Fengxi Chemical

Specifications

HS Code	146211
Chemical Formula	C8H9IO
Molecular Weight	248.06 g/mol
Appearance	Colorless to light yellow liquid
Boiling Point	Approximately 240 - 245 °C
Density	Around 1.68 - 1.7 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, ether, chloroform
Flash Point	Approximately 105 - 110 °C
Vapor Pressure	Low at room temperature
Chemical Formula	C8H9IO
Molecular Weight	248.06
Appearance	colorless to light yellow liquid
Boiling Point	253 - 255 °C
Density	1.715 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, ether
Purity Usually	Typically high - purity grades available around 95%+
Cas Number	23074 - 56 - 6

As an accredited 4-Ethoxyiodobenzene, 4-Iodophenyl Ethyl Ether factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 4 - ethoxyiodobenzene (4 - iodophenyl ethyl ether) in a sealed glass bottle.
Storage	4 - ethoxyiodobenzene (4 - iodophenyl ethyl ether) should be stored in a cool, dry place away from heat and ignition sources. Keep it in a tightly sealed container to prevent exposure to air and moisture, which could potentially lead to decomposition. Store it separately from oxidizing agents and incompatible substances to avoid chemical reactions.
Shipping	4 - ethoxyiodobenzene (4 - iodophenyl Ethyl Ether) is shipped in well - sealed, corrosion - resistant containers. Special care is taken to prevent leakage during transit as it's a chemical, following all relevant safety and regulatory guidelines for chemical shipments.

Free Quote

Competitive 4-Ethoxyiodobenzene, 4-Iodophenyl Ethyl Ether prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@bouling-chem.com.

We will respond to you as soon as possible.

Tel: +8615371019725

Email: sales7@bouling-chem.com

4-Ethoxyiodobenzene, 4-Iodophenyl Ethyl Ether

General Information

Historical Development

4-Ethoxyiodobenzene and 4-Iodophenyl Ethyl Ether are actually the same substance and are organic compounds. Tracing its historical development, organic chemistry was first emerging in the past, and chemists focused on the exploration and synthesis of various compounds. At that time, the conditions were limited, and the understanding of many substances was still shallow.
The discovery of this compound was the result of unremitting experimentation and research by chemists. Early organic synthesis technology was still immature, and it was quite difficult to synthesize this compound. It was necessary to repeatedly explore the reaction conditions and the ratio of raw materials. With the gradual development of chemical technology, many new synthesis methods emerged, which improved the synthesis efficiency and gradually increased the yield. From the initial accidental discovery to the subsequent in-depth study of its properties and applications, this compound has become increasingly important in the field of organic synthesis, laying the foundation for many related studies and promoting the continuous development of organic chemistry.

Product Overview

4-Iodophenyl Ethyl Ether is an important compound in the field of organic synthesis that has attracted much attention. Its molecular structure is unique. It is based on a benzene ring, with an iodine atom at one end and an ethoxy group at the other end.
This compound is often used as a key intermediate in organic synthesis. With the activity of iodine atoms, various functional groups or carbon chains can be introduced through many reactions, such as coupling reactions, to construct complex organic molecules. The existence of ethoxy groups not only affects the physical properties of molecules, such as solubility, but also regulates their reactivity and selectivity.
In the fields of fine chemistry and drug research and development, 4-ethoxyiodobenzene is indispensable. In fine chemistry, it is used to prepare high-end organic materials; in drug development, it provides key starting materials for the synthesis of specific structure drug molecules. In short, it plays a significant role in the field of organic synthesis and has broad prospects.

Physical & Chemical Properties

The physicochemical properties of 4-ethoxy iodobenzene, also known as 4-iodophenyl ethyl ether, are particularly important. Its color is pure, usually solid at room temperature, and its texture is fine. The melting point is in a specific range. When the temperature changes, the state of the substance changes from solid to liquid, which is the key performance of its physical properties.
When it comes to chemical properties, 4-ethoxy iodobenzene has certain reactivity. In its molecular structure, ethoxy interacts with iodobenzene, which makes the substance exhibit unique properties in many chemical reactions. In the field of organic synthesis, due to its specific structure, it can be used as a key raw material to participate in various reaction pathways, providing the possibility for the synthesis of complex organic compounds. Due to its unique physical and chemical properties, it has wide application prospects in chemical industry, pharmaceutical research and development, and is a substance that cannot be ignored in chemical research and industrial production.

Technical Specifications & Labeling

The preparation process of 4-ethoxyiodobenzene, also known as 4-iodophenyl ethyl ether, requires strict procedures. First, in a clean reactor, the raw materials are put into the raw materials according to the precise ratio, and the ratio of iodobenzene to ethyl alcohol etherification agent should be appropriate, which is related to the purity and yield of the product. The reaction temperature should be controlled in a specific range to ensure a smooth etherification reaction. During the reaction process, continue to stir to make full contact with the material. After the reaction is completed, the product is refined through distillation, extraction and other steps.
The identification of the product is related to the quality, and various parameters must be recorded in detail. The appearance should be a colorless to slightly yellow liquid with a pure smell. The purity determination needs to meet specific standards, and the impurity content is strictly controlled. Physical parameters such as melting point and boiling point also need to be accurately determined as key indicators of quality. On the packaging, the product name, specification, batch and date must be clearly marked to ensure that the product can be traced back to meet the needs of the market and quality control.

Preparation Method

To prepare 4-ethoxyiodobenzene (4-iodophenyl ethyl ether), it is necessary to understand the method of preparation. The raw materials used should be iodobenzene and ethanol. The preparation process is as follows:
First, iodobenzene and an appropriate amount of ethanol are placed in a reactor, a catalyst is added, and the temperature is heated to a suitable temperature. At the beginning of the reaction, the two slowly combine and the molecules interact. This reaction goes through multiple steps, and the iodine atom of iodobenzene is gradually connected to the ethoxy group of ethanol.
The reaction process needs to be carefully regulated, and the temperature and pressure are adjusted in time according to the reaction progress. After the reaction is completed, the impurities are removed through the steps of separation and purification, and pure 4-ethoxyiodoben In this method, the catalyst is the key, which can promote the reaction rate and affect the purity and yield of the product. Therefore, the desired 4-Ethoxyiodobenzene can be prepared by this method.

Chemical Reactions & Modifications

Guanfu 4 - Ethoxyiodobenzene and 4 - Iodophenyl Ethyl Ether, the two chemical substances, the reaction and change, can be quite studied.
The chemical reaction of the husband, such as the interaction of yin and yang, is pushed back by rigidity and softness. In these two substances, either heat and change, or every agent. The clutch of its bonds, the fusion and dispersion of atoms, all follow the principles of chemistry.
However, if you want to improve its change, make the reaction smooth, and the product is excellent, you must investigate all the reasons in detail. The influence of temperature is not small, if it is too high, it will be messy, if it is too low, it will be slow and stagnant. And the nature of the solvent also affects it, and the appropriate agent can help the reaction to be smooth.
And the design of the catalyst, if well-crafted, can change the path of the reaction, reduce the force required, promote its speed and increase its yield. Therefore, in the reaction of the two, good adjustment of various causes can make it easier to meet the requirements, turn decay into magic, and achieve the best of chemical research.

Synonyms & Product Names

4-Ethoxy iodobenzene, also known as 4-iodophenyl ethyl ether, the alias and trade name of this substance are things that need to be detailed in chemical research. During my chemical research, I knew that there are often more than one substance. 4-ethoxy iodobenzene, from its structure, ethoxy and iodine atoms are connected to the phenyl ring, showing unique chemical properties. Its alias 4-iodophenyl ethyl ether also accurately describes the molecular composition, and ethyl ether groups are connected to iodobenzene.
In chemical trade and academic research, the distinction between aliases and trade names is very important. Accurate appellation can avoid confusion and ensure the correct transmission of information. Chemical synthesis and material research and development rely on precise names to advance experiments and production in an orderly manner. 4-Ethoxy iodobenzene or 4-iodophenyl ethyl ether, although different names, refers to the same substance, and chemical researchers need to be familiar with it in order to avoid ambiguity and errors in their work.

Safety & Operational Standards

4-Ethoxyiodobenzene (4-Ethoxyiodobenzene), also known as 4-Iodophenyl Ethyl Ether (4-Iodophenyl Ethyl Ether), this compound is essential for safety and operation in experimental and industrial applications.
For storage, it should be placed in a cool, dry and well-ventilated place, away from fire and heat sources. Because of its certain chemical activity, it is necessary to store it in isolation from oxidizing agents, strong acids and other substances to prevent violent chemical reactions, such as oxidation reactions, which may cause combustion or explosion. The packaging must also be well sealed to avoid contact with moisture, oxygen and other components in the air to prevent deterioration.
During operation, the experimenter must take protective measures. Wear appropriate protective gloves. The material should be suitable to resist the erosion of the compound to prevent it from contacting the skin and causing chemical burns. Wear protective glasses to avoid it splashing into the eyes and causing damage to the eye tissue. The operation should be carried out in a fume hood. If the conditions are limited, it is also necessary to ensure that the operating environment is well ventilated, and the volatile gas should be discharged in time to prevent human inhalation and cause damage to the respiratory tract and nervous system.
When taking the compound, clean and dry appliances should be used, and the dose should be accurately measured strictly according to the experimental requirements to avoid waste and pollution. If it is accidentally spilled, proper cleaning measures should be taken immediately. When a small amount is spilled, it can be carefully wiped with a clean rag, and properly disposed of after collection; if a large amount is spilled, it is necessary to evacuate personnel in time, start the emergency ventilation device, and cover the adsorption with appropriate adsorption materials, and then dispose of it according to the hazardous waste treatment process.
When operating a chemical reaction, it is necessary to precisely control the reaction conditions, such as temperature, pressure, reaction time, etc. Due to high temperature or long reaction time, side reactions may occur, affecting the purity of the product, and even causing safety accidents.
Only by strictly following the above safety and operating practices can we ensure the safety and effectiveness of 4-Ethoxyiodobenzene or 4-Iodophenyl Ethyl Ether during use, and ensure the safety of personnel and the smooth progress of experiments and production.

Application Area

Today there is a product called 4 - Ethoxyiodobenzene, also known as 4 - Iodophenyl Ethyl Ether. The application field of this product is quite critical. In the field of organic synthesis, it is often used as a key intermediate. Based on it, many organic compounds can be derived, just like a skilled craftsman builds a building with good materials.
In the field of medicinal chemistry, its contribution should not be underestimated. Through exquisite synthesis paths, it is integrated into the molecular structure of drugs, which may endow drugs with unique activities and heal various diseases.
Furthermore, in the field of materials science, its special chemical properties can optimize material properties. Such as participating in the creation of new functional materials, making materials have better photoelectric properties, etc., to contribute to material innovation. This is the outline of the 4 - Ethoxyiodobenzene application field.

Research & Development

Today there is a thing called 4 - Ethoxyiodobenzene, also known as 4 - Iodophenyl Ethyl Ether. We take research and development as our business, and study it in detail.
The properties of this thing are related to its structure and composition. Its molecular structure is unique, or it has a different chemical activity. At the beginning of research, analyze its components, distinguish its characteristics, and hope to understand its reaction in different situations.
The way of development lies in expanding its use. Or in the field of synthesis, add bricks to the creation of new substances; or in the field of materials, give materials novel properties. After many tests, accumulating a lot of data is the way to find the best.
We are unswervingly committed to exploring and expanding its applications with scientific methods, with the aim of making achievements in the path of research and development, so that this thing can be used by the world and benefit people.

Toxicity Research

Looking back at this world, there is a thing called 4-Ethoxyiodobenzene, also known as 4-Iodophenyl Ethyl Ether. Our generation focuses on the study of poisons.
This substance is also unknown in its nature, so it is all the research. It may involve the field of chemical industry, or it may be related to medicine. However, the nature of poisons cannot be ignored. If used improperly, it may cause harm to people and the surrounding area.
If you want to understand its toxicity, you must use scientific methods to observe its response to other things and observe the changes in its entry into the body. With ancient methods, today's equipment, explore its nature in detail. It is good to hope to obtain the true meaning in order to avoid its harm and use it for good, so that this thing is not a disaster to the world, but a thing that benefits others.

Future Prospects

Fu 4 - Ethoxyiodobenzene is 4 - Iodophenyl Ethyl Ether, which has an extraordinary future prospect in the field of my chemical research. Its unique structure, the arrangement and combination of molecules, seem to hide endless mysteries to be explored by us.
Looking at the present, although there are still limitations in its understanding, I firmly believe that with time, with the help of more and more advanced research methods, its deep properties and reaction mechanism will be able to be understood.
In the future, it may emerge in the research and development of new materials. With its special chemical properties, it may be able to construct functional materials with excellent performance, which can be used in many cutting-edge fields such as electronics and optics.
Or in the process of organic synthesis, it may become a key intermediate to help synthesize more complex and unique compounds. This is my vision for its future development, and I will do my best to devote myself to research to prove that this vision is not false.

Historical Development

The author of 4 - Ethoxyiodobenzene, that is, 4 - Iodophenyl Ethyl Ether, can be described in the history of its products. For the first time, the person who made it was carefully studied in the room, hoping to have some results. It is not easy to do, either because the reverse parts are not negotiated, or because the raw materials are not good, and the results are not yet effective. However, no one has yet said it, and it is supported by exploration. The first time the method of improvement and the matching of the reverse materials have been improved, so that the synthesis of this compound has become mature. The synthesis of the past has been smooth in the past, and it is useful in many fields. It can be turned into an important milestone on the way to development. It is an important milestone that has been achieved through the exploration of our company.

Product Overview

4-Ethoxyiodobenzene, also known as 4-Iodophenyl Ethyl Ether, is a chemical compound that we have recently investigated. It consists of chemical compounds with specific chemical properties.
In this compound, the iodine atom is in the phase of benzene, and the ethoxy group is also attached to the benzene group. In this way, it has a certain chemical activity. It is physical. It is often low or solid, and the color is white or white. Its melt-boiling equivalence is due to the dense phase of its molecules.
In the chemical reaction, the iodine atom can be used as an active site, such as the even reaction. The existence of ethoxy groups also affects the distribution of molecular sub-clouds, and the direction of the left and right reaction. We will explore its inverse properties from a variety of sources, hoping to better understand its effectiveness in the field of chemical synthesis.

Physical & Chemical Properties

The physical and chemical properties of 4-ethoxyiodobenzene, also known as 4-iodophenyl ethyl ether, are very important. Its appearance is often off-white to light yellow crystalline powder. The melting point is in a specific range, about [X] ° C, which is of great significance in the identification and purification process. The boiling point also has a corresponding value, about [X] ° C, which depends on its state change at different temperatures.
In terms of solubility, 4-ethoxyiodobenzene has a certain solubility in organic solvents such as ethanol and ether, but its solubility in water is very small. This property determines its application in various chemical reactions and separation operations. Its chemical stability is acceptable under normal conditions, but when it encounters strong oxidizing agents, strong acids and bases, it is prone to chemical reactions and its structure or properties will change. Such physical and chemical properties make it unique in the fields of organic synthesis and so on.

Technical Specifications & Labeling

4-Ethoxyiodobenzene (4-Ethoxyiodobenzene), also known as 4-Iodophenyl Ethyl Ether (4-Iodophenyl Ethyl Ether), its preparation process and standards (product parameters) are crucial.
Preparation of this product requires specific process procedures. First take an appropriate amount of iodobenzene, add an appropriate amount of ethanol and alkali in a precise way, and fully react at a suitable temperature and pressure. When reacting, it is necessary to closely monitor the reaction process and observe its changes with professional instruments to control the direction and degree of reaction.
Product standards are related to many parameters. Appearance should be colorless to slightly yellow liquid without obvious impurities. The purity must reach a specific proportion or more, and the impurity content is strictly limited. Its boiling point, melting point and other physical properties also need to fall within the established range. In this way, the quality of the product can be guaranteed to meet the needs of the market and industrial applications.

Preparation Method

The method of making 4-ethoxyiodobenzene (4-Iodophenyl Ethyl Ether) is related to the raw materials and production process, reaction steps, and catalytic mechanism. The raw materials are selected from refined iodine, p-ethoxy phenol, etc. First put an appropriate amount of p-ethoxy phenol in the reaction kettle, add a catalyst, adjust it to a specific temperature, and slowly inject refined iodine. During this time, the catalyst promotes the reaction to proceed quickly, and the molecules are active and phased. The reaction steps are rigorous, and the temperature is controlled in a certain range to prevent side reactions. The temperature and stirring rate are adjusted in a timely manner according to the reaction process to ensure the uniformity of the reaction. In the catalytic mechanism, the catalyst decreases the activation energy of the reaction, increases the molecular collision frequency and the effective collision number, and causes the reaction to be efficient. Through this series of operations, relatively pure 4-ethoxy iodobenzene can be obtained, which can provide high-quality raw materials for chemical industry and scientific research.

Chemical Reactions & Modifications

I am going to study the anti-modification of 4-Ethoxyiodobenzene, that is, the anti-modification of 4-Iodophenyl Ethyl Ether. For this compound, the way of its anti-modification can be explored. In the field of chemical transformation, if you want to understand its properties, you must check its anti-modification.
Its anti-modification may be different due to the quality of the product and the quality of the product. For example, the rise and fall of the temperature and the change of the dissolution can affect the process of its anti-modification. Or promote its formation, or inhibit it.
As for the modification, it is designed to reduce its properties and meet different needs. Or increase its performance, or improve its activity. When it comes to exploring, it is necessary to follow the rules and investigate the rules, so that you can obtain the best ones and use them.

Synonyms & Product Names

Today there is a thing called 4 - Ethoxyiodobenzene, also known as 4 - Iodophenyl Ethyl Ether. These two are actually the same thing but have different names. In my chemical exploration, the same thing is common but many. Although the names are different, the things they refer to are one. This 4 - Ethoxyiodobenzene, or 4 - Iodophenyl Ethyl Ether, is a common raw material for organic synthesis. In the reaction, its properties are unique, and it can combine with various reagents to form new substances. Although there are two names, their essence is this specific chemical substance. In chemistry, there are many people with different names, and this is only one example. We should be clear about the reason, check the quality, and not be confused by the difference in its name, so that we can explore the seclusion and make progress in the realm of chemistry.

Safety & Operational Standards

4-Ethoxyiodobenzene (4-Iodophenyl Ethyl Ether) Safety and Handling Specifications
Fu 4-ethoxyiodobenzene, also known as 4-Iodophenyl Ethyl Ether, is a compound commonly used in chemical research. During its experimental operation, safety and standardized operation are of paramount importance.
First words are safe. This compound has certain chemical activity or potential harm to human body. When operating, appropriate protective equipment must be worn, such as laboratory clothes, gloves and goggles. Gloves should be made of suitable materials to prevent compound penetration. Goggles can effectively protect the eyes from accidental splashing injuries. If you accidentally contact the skin, you should immediately rinse with a large amount of water and seek medical treatment if necessary. If you splash into the eye, you need to rinse quickly and seek professional medical assistance as soon as possible.
Times and operating specifications. When weighing, a precise balance should be used and in a well-ventilated environment to prevent the diffusion of compound dust. During the dissolution or reaction process, the temperature and speed should be strictly controlled according to the reaction conditions. When heating, use suitable heating equipment to avoid local overheating causing the decomposition of compounds or causing danger. The stirring process should also be smooth to prevent the solution from splashing out.
After the reaction is completed, the treatment of the product should not be ignored. According to the nature of the compound, suitable separation and purification methods should be used. Waste should be collected in accordance with regulations and should not be discarded at will to avoid polluting the environment.
In conclusion, in the research operation of 4-ethoxyiodobenzene, strict adherence to safety and operating standards can ensure the smooth operation of the experiment, ensure the safety of researchers, and protect the environment from damage.

Application Area

4-Ethoxyiodobenzene (4-Ethoxyiodobenzene), also known as 4-Iodophenyl Ethyl Ether (4-Iodophenyl Ethyl Ether), is widely used in the field of chemical medicine.
In the process of organic synthesis, it is a key intermediate. Due to its special structure, the presence of iodine atoms and ethoxy groups endows it with active reactivity. Through many chemical reactions, such as nucleophilic substitution reactions, various functional groups can be introduced to build complex organic molecular structures, laying the foundation for the creation of new drugs and functional materials.
In the context of drug development, it may participate in the construction of specific drug molecules. With its unique chemical properties, it can precisely adjust the spatial structure and electron cloud distribution of drug molecules, thereby optimizing the activity, selectivity and pharmacokinetic properties of drugs.
has also made its mark in the field of materials science. After rational chemical modification and assembly, materials with special optoelectronic properties can be prepared, such as in organic Light Emitting Diodes, solar cells and other fields, which contribute to the improvement of material properties.

Research & Development

In recent years, I have focused on the research of 4-Ethoxyiodobenzene, that is, 4-Iodophenyl Ethyl Ether. This substance has unique properties and great potential in the field of organic synthesis.
At the beginning, the synthesis path was explored, and the raw materials and conditions were screened through repeated experiments. Using iodobenzene as a base, a suitable ethylation reagent was found, and the reaction temperature, duration and catalyst influence were considered. After many failures, a feasible method was finally obtained, and the yield gradually increased.
The reactivity was studied, and the reaction mechanism was investigated by interacting with compounds with different functional groups. It was found that under specific conditions, it can efficiently participate in the coupling reaction, paving the way for the creation of new organic materials.
Looking to the future, we hope to optimize the synthesis process, reduce costs, improve efficiency, and expand its applications. Or for drug research and development, using its structural characteristics to create special drugs; or for materials science to give new properties to materials. I will do my best to promote the development of this product and add bricks and mortar to the chemical field.

Toxicity Research

The industry of chemical industry is related to people's livelihood. However, things have yin and yang, and there are advantages and disadvantages. In today's words, 4 - Ethoxyiodobenzene and 4 - Iodophenyl Ethyl Ether are both chemical products.
In the study of toxicity, it is necessary to observe. We are cautious to explore its properties. Although it may be beneficial in industrial applications, the harm of toxicity can be underestimated? After various experiments, observe its impact on life, and observe its changes in the environment. Or damage the ability of the body, or disrupt the balance of ecology.
The study of toxicity is an important part of the chemical industry. Only by understanding its harm can we avoid its risks and make good policies to protect the people and the environment. Therefore, the toxicity of 4 - Ethoxyiodobenzene and 4 - Iodophenyl Ethyl Ether should be studied carefully and dare not be ignored.

Future Prospects

Today there is a thing called 4 - Ethoxyiodobenzene, also known as 4 - Iodophenyl Ethyl Ether. We study it in chemistry, observe its characteristics, and think about its future development. This thing may have extraordinary uses in the field of chemical industry. Although our knowledge is limited today, our generation has high expectations and hopes that it will shine in the future. I hope to understand its mechanism, expand its application, and make achievements in medicine and materials. Make this material contribute to the progress of science and technology in the future, so as to become the grand aspiration of our hearts and develop the infinite possibilities of the future.

Where to Buy 4-Ethoxyiodobenzene, 4-Iodophenyl Ethyl Ether in China?

As a trusted 4-Ethoxyiodobenzene, 4-Iodophenyl Ethyl Ether manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 4-Ethoxyiodobenzene, 4-Iodophenyl Ethyl Ether supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the main use of 4-ethoxyiodobenzene, 4-iodophenyl Ethyl Ether?

4-Ethoxyiodobenzene (4-ethoxyiodobenzene) and 4-iodophenyl ethyl ether (the two are actually the same substance) have a wide range of main uses.
In the field of organic synthesis, it is often used as a key intermediate. The presence of iodine atoms and ethoxy groups in the molecule gives it unique reactivity. Iodine atoms can participate in a variety of coupling reactions, such as the Ullmann reaction, whereby carbon-carbon bonds, carbon-heteroatomic bonds, etc. can be formed to synthesize complex organic compounds, which are of great significance in drug development, materials science, etc.
In the field of medicinal chemistry, with this as the starting material, other active groups can be introduced through a series of reactions to prepare compounds with specific pharmacological activities. For example, by modifying the substituents on the benzene ring, the physical and chemical properties of the compound such as lipophilicity and electron cloud density can be adjusted, and then its interaction with biological targets can be optimized to improve the efficacy and selectivity of drugs.
In the field of materials science, it can be used to synthesize functional polymer materials. It is connected to the polymer skeleton by coupling reaction to endow the material with unique optical and electrical properties. For example, synthesizing polymers with photoelectric activity can be used in organic Light Emitting Diodes (OLEDs), solar cells and other optoelectronic devices to improve the performance and efficiency of the device.
In addition, 4-ethoxyiodobenzene also plays an important role in the preparation of fine chemical products. It can be used to prepare special structures of fragrances, dyes, etc. With its unique chemical structure, it imparts novel characteristics and quality to the products.

What are the physical properties of 4-ethoxyiodobenzene, 4-iodophenyl Ethyl Ether

The physical properties of 4-ethoxyiodobenzene (4-ethoxyiodobenzene) and 4-iodophenyl ethyl ether (4-iodophenyl Ethyl Ether, the same substance as 4-ethoxy iodobenzene) are quite important for their application in various fields.
Looking at its appearance, at room temperature, 4-ethoxyiodobenzene mostly appears as a colorless to light yellow liquid, which is easy to intuitively identify. It has a certain volatility and can slowly emit a smell in the air. However, this smell is not pungent and intolerable, but has a slightly special aromatic aroma. Although it is not strong, it can be distinguished.
When it comes to the melting point, the melting point is about [X] ° C. Under this temperature condition, the substance changes from solid to liquid, showing a phase change. The boiling point is around [X] ° C. When the temperature rises to the boiling point, the liquid will violently vaporize and turn into a gaseous state. This boiling point characteristic has a significant impact on separation, purification and storage. To separate this substance, it can be achieved by distillation according to its boiling point.
4-ethoxyiodobenzene has a slightly higher density than water, about [X] g/cm ³. When mixed with water, it will sink to the bottom. This property needs to be taken into account when it comes to liquid-liquid separation operations.
In terms of solubility, it is insoluble in water, because water is a highly polar solvent, while 4-ethoxy iodobenzene has a weaker polarity, and according to the principle of "similar miscibility", the two are difficult to miscible. However, it is soluble in many organic solvents, such as ethanol, ether, chloroform, etc., and can be well dispersed in these organic solvents to form a uniform solution. This property is of great significance when used as a solvent or reactant in organic synthesis reactions, which can promote the smooth progress of the reaction.
In addition, the refractive index of 4-ethoxy iodobenzene is also one of its important physical properties, about [X]. The refractive index reflects the degree of deflection of light when propagating in the substance, and is involved in the research or application of optical materials.
The above physical properties are related to each other, and together outline the characteristics of 4-ethoxy iodobenzene, which lays the foundation for its application in many fields such as chemical industry and medicine.

Is 4-ethoxyiodobenzene, 4-iodophenyl Ethyl Ether chemically stable?

The chemical properties of 4-ethoxyiodobenzene (4-ethoxyiodobenzene) and 4-iodophenyl ethyl ether (4-iodophenyl Ethyl Ether, which is different from 4-ethoxyiodobenzene for the same substance) are relatively stable.
In this compound, the benzene ring is a stable conjugated system, which endows it with a certain degree of stability. Although the iodine atom has a certain activity and can undergo reactions such as nucleophilic substitution, the reactivity is restricted to a certain extent due to the conjugation of the benzene ring. The ethoxy group is connected to the benzene ring, and the electron cloud density of the benzene ring is further enhanced through the electron-giving conjugation effect, which contributes to the stability of the whole molecule. Under normal environmental conditions, without specific reagents, catalysts and suitable reaction conditions, 4-ethoxy iodobenzene will not easily undergo chemical reactions. However, in some specific scenarios, iodine atoms may be replaced in case of strong nucleophiles; under extreme conditions such as high temperature and light, the molecular structure may undergo some changes, but overall, in conventional storage and general experimental environments, its chemical properties are relatively stable and its own structure and properties can be maintained unchanged.

What is the preparation method of 4-ethoxyiodobenzene, 4-iodophenyl Ethyl Ether

To prepare 4-ethoxyiodobenzene (4-iodophenyl ethyl ether), which is 4-iodophenyl ethyl ether (4-iodophenyl ethyl ether), the following ancient methods can be used.
The method of nucleophilic substitution is first proposed. Using 4-iodophenol and haloethane as raw materials, this reaction can be carried out in an alkaline environment. Take an appropriate amount of 4-iodophenol and place it in the reaction vessel, and then add alkaline substances such as potassium carbonate slowly. Using alcohols as solvents, such as ethanol, can help dissolve and promote the reaction. After stirring well, add haloethane dropwise. Depending on the activity of haloethane, if it is bromoethane or iodoethane, the activity is higher, and the reaction conditions can be slightly milder; if it is chloroethane, the activity is slightly lower, and the reaction time needs to be properly heated and prolonged. Under heating and stirring, the phenolic hydroxyl oxygen atom of 4-iodophenol acts as a nucleophilic reagent to attack the α-carbon atom of haloethane, and the halogen ion leaves, and 4-ethoxyiodobenzene is obtained. After the reaction is completed, the pure product can be obtained by conventional separation and purification methods, such as extraction, distillation, column chromatography, etc.
Furthermore, it can be prepared by the electrophilic substitution reaction of phenyl ring. First, benzene is used as the starting material and ethoxylated to obtain eth The mixed acid of concentrated sulfuric acid and concentrated nitric acid is used as the nitrifying reagent to nitrate ethyl ether, and the nitro group is introduced at the para-position of the benzene ring. After the reduction step, the nitro group is reduced to the amino group by the reduction system such as iron powder and hydrochloric acid to obtain p-ethoxyaniline. The diazonium salt solution composed of sodium nitrite and hydrochloric acid reacts with p-ethoxyaniline at low temperature to form a diazonium salt. Subsequently, the potassium iodide solution is added, the diazonium group is replaced by the iodine atom, and the final 4-ethoxyiodobenzene is obtained. This route step is slightly complicated, but the raw material is easy to obtain, and the reaction conditions of each step are relatively mature.
Another cross-coupling reaction catalyzed by p 4-Iodohalobenzene and sodium ethanol are used as raw materials to react in the presence of palladium catalysts and ligands. Commonly used palladium catalysts such as tetra (triphenylphosphine) palladium (0), ligands such as tri-tert-butylphosphine, etc. The reaction is carried out in an appropriate organic solvent such as N, N-dimethylformamide (DMF). Under heating and inert gas protection, halogen atoms are cross-coupled with the ethoxy group of sodium ethanol to form the target product 4-ethoxyiodobenzene. This method is efficient and selective, but the cost of catalysts and ligands is high, and the requirements for reaction equipment and operation are also stricter.

What is the price range of 4-ethoxyiodobenzene, 4-iodophenyl Ethyl Ether in the market?

I think what you are asking is the price range of 4-ethoxyiodobenzene (4-ethoxyliodobenzene) and 4-iodophenyl Ethyl Ether (4-iodophenyl ethyl ether) in the market. However, the price of the two in the market often changes due to many reasons, and it is difficult to determine a certain number.
First, the price of raw materials often changes due to time, geographical location, and supply and demand. If the raw materials required for its preparation are rare, or there are disasters or wars in the place of origin, which make the raw materials difficult to harvest, the price must be high. Such as ancient treasures, because it is not easy to produce, the price is high and rare.
Second, the method of preparation also affects its price. If the preparation process is complicated, requires multiple processes, takes a long time, consumables are many, and labor is huge, then the price will be high. The exquisite craftsmanship of ancient times is time-consuming and laborious, and the finished product is precious.
Third, the supply and demand of the city is also the main reason. If there are many applicants for this product, but there are few suppliers, the price will rise; if the supply exceeds the demand, the price will drop. Just like the reason that the valley is low in a good year, and the valley is expensive in a bad year.
Today, 4-ethoxyiodobenzene and 4-iodophenyl ethyl ether are in the market, and their prices range from tens to hundreds of yuan per gram. However, this is only an approximate number, and the actual price should be subject to the quotation of each supplier and the real-time market conditions. To know the exact price, you need to check the dynamics of the market in detail and consult the merchants before you can get it.