4-Ethyliodobenzene

Fengxi Chemical

Specifications

HS Code	808237
Chemical Formula	C8H9I
Molecular Weight	218.06
Appearance	Colorless to yellow liquid
Boiling Point	211 - 212 °C
Melting Point	-22 °C
Density	1.572 g/mL at 25 °C
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in many organic solvents like ethanol, ether
Flash Point	87 °C
Odor	Characteristic aromatic odor
Vapor Pressure	Low vapor pressure

As an accredited 4-Ethyliodobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500 - gram bottle of 4 - ethyliodobenzene, tightly sealed in chemical - resistant packaging.
Storage	4 - ethyliodobenzene should be stored in a cool, dry, well - ventilated area away from heat sources and open flames. It should be kept in a tightly sealed container, preferably made of corrosion - resistant materials. Avoid storing it near oxidizing agents. Store it at a temperature below 30°C to prevent decomposition and potential safety hazards.
Shipping	4 - ethyliodobenzene is shipped in accordance with strict chemical transport regulations. Packed in suitable, leak - proof containers, it's transported by approved carriers, ensuring safety during transit to prevent any environmental or safety hazards.

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General Information

Historical Development

4-Ethyliodobenzene is also an organic compound. Its traces can be traced back to the process of chemical inquiry in the past. In the past, chemical sages were dedicated to the improvement of organic synthesis. In the long exploration, the research on benzene derivatives became more and more profound.
At that time, organic chemistry was in the ascendant, and scholars worked hard to find a wonderful way to transform substances. 4-Ethyliodobenzene then emerged in the synthetic ingenuity. At the beginning, the synthesis method was cumbersome and the yield was meager, but chemists were determined and made unremitting improvements.
After generations of research, the synthesis technology is becoming more and more mature. The reaction conditions are gradually milder, and the yield is also steadily increasing. From the prototype of the laboratory to the large-scale preparation, the development of 4-Ethyliodobenzene reflects the progress of chemistry, and its use in the field of organic synthesis has become more and more extensive, laying the foundation for many subsequent studies and applications, and forming an indispensable chapter in the development of chemistry.

Product Overview

4-Ethyliodobenzene is an important raw material for organic synthesis. Its appearance is colorless to pale yellow liquid with a unique odor. The compound is composed of benzene ring, ethyl group and iodine atoms.
In terms of chemical properties, iodine atoms are highly active and easily participate in nucleophilic substitution reactions. This property makes 4-Ethyliodobenzene play a key role in the preparation of various benzene-containing derivatives. The presence of ethyl groups alters the electron cloud density of benzene rings and affects the reactivity and selectivity of compounds.
In the field of organic synthesis, 4-Ethyliodobenzene is widely used to construct complex organic molecular structures, contributing to the development of medicinal chemistry, materials science and many other disciplines. By ingeniously designing reaction pathways, it can be used to synthesize organic compounds with specific functions and structures, providing a key material foundation for research and application in related fields.

Physical & Chemical Properties

4 - Ethyliodobenzene is an organic compound with unique physical and chemical properties. Its physical properties are liquid at room temperature, with a specific color and odor, specific boiling point and melting point, and its solubility is different from that of organic solvents. Its chemical properties are stable benzene ring, active iodine atom, and can participate in nucleophilic substitution reactions. In case of nucleophilic reagents, iodine is easily replaced to form new compounds. Ethyl can participate in alkylation reactions. This compound is widely used in the field of organic synthesis and can be used as a raw material or intermediate to synthesize complex organic molecules. Researchers often explore its reaction conditions and mechanism to optimize the synthesis path, improve the purity and yield of the product, and promote the development of organic chemistry.

Technical Specifications & Labeling

4-Ethyliodobenzene is also an organic compound. Its process specifications and identification (product parameters) are essential for production and application.
In terms of its process specifications, the purity needs to reach a very high level, and the impurity content must be strictly controlled. The synthesis method needs to be carefully controlled according to the precise steps, the ratio of materials, the temperature and duration of the reaction. At the time of reaction, or the method of iodine substitution, ethylbenzene and iodine reagents interact, and the conditions are suitable to obtain high-purity products.
As for the identification (product parameters), in addition to the clear chemical name "4-Ethyliodobenzene", its physical and chemical properties need to be indicated. For example, the appearance should be colorless to light yellow liquid, with specific boiling point, melting point and density. And the conditions for storage need to be clear, and it should be stored in a cool place away from light to prevent deterioration. In this way, this material can be used correctly in various fields of chemical industry and play its role.

Preparation Method

To prepare 4-Ethyliodobenzene, the raw materials are crucial to the production process, reaction steps and catalytic mechanism. First take an appropriate amount of iodobenzene as the starting material and dissolve it in a specific organic solvent to ensure uniform dispersion. Then add an appropriate amount of ethylation reagent, which is the key to introducing ethyl. Add a specific catalyst to the reaction system to efficiently promote the reaction, precisely control the catalytic mechanism, and improve the reaction rate and yield.
The reaction steps are as follows: Under suitable temperature and pressure conditions, continuously stir the mixture to fully contact the reactants. Close monitoring of the reaction process, fine-tuning the temperature and pressure according to the reaction conditions to ensure the smooth progress of the reaction. When the reaction reaches the desired level, it is purified through a series of post-processing operations, such as extraction, washing, drying, etc.
The whole preparation process, the selection of raw materials, the control of reaction conditions and the use of catalytic mechanisms are all crucial, and fine operation is required to obtain high-purity 4-Ethyliodobenzene products.

Chemical Reactions & Modifications

In recent years, chemical compounds have been studied in the synthesis and modification of 4-Ethyliodobenzene. The reaction path of this compound is often related to the reaction conditions and the reagents used. In the past, the conventional method may have the disadvantages of low yield and complicated side effects.
We then think about the way of change, try to use new agents and adjust their conditions. In terms of temperature, pressure, and catalyst, all aspects are considered in detail. At a suitable temperature, supplemented by a specially prepared catalyst, the reaction of 4-Ethyliodobenzene can increase the yield and decrease the side effects.
When modifying, we use subtle methods to adjust the molecular structure. Or adding groups, or changing bonds, so that its physical properties and chemical properties are fickle. In this way, 4-Ethyliodobenzene is used in various fields more widely. This is the way of chemical research, constantly seeking to improve the environment, so that the chemical application and modification can be suitable for the needs of the world.

Synonyms & Product Names

4-Ethyliodobenzene, which has attracted much attention in chemical research. The study of its alias and trade name is of great importance in the academic world.
In the past, the names of chemical substances were often different due to regions and habits. 4-Ethyliodobenzene is also known as o-ethyliodobenzene, which is named according to the relative position of ethyl and iodine atoms in its molecular structure. In inter-city trade, or there are trade names called by specific trade names, which are designed to recognize its unique quality and use.
Investigating its chemical nature, 4-Ethyliodobenzene has the characteristics of aromatics, and the substitution of ethyl and iodine atoms gives it another reactivity. In the field of organic synthesis, it is often a key intermediate, which can be derived from a variety of organic compounds through many reaction paths. Due to the complexity of its aliases and trade names, it can be seen that the development of the chemical industry is in the vein. Scholars and merchants from all over the world have given it different names based on their own understanding and needs, but they all revolve around this core substance, promoting the research and application of organic chemistry.

Safety & Operational Standards

4 - Ethyliodobenzene is an organic compound. It is crucial to discuss in detail the safety and operation specifications of this product.
In terms of safety, the first toxicity awareness. 4 - Ethyliodobenzene may have certain toxicity. If it is inadvertently exposed, whether it is absorbed through the skin, mistakenly inhaled its volatile gas, or accidentally ingested, it may endanger human health. Therefore, it is necessary to wear appropriate protective equipment during operation, such as gloves, anti-goggles and gas masks, to prevent the possibility of contact.
Furthermore, the risk of ignition cannot be ignored. Under certain conditions, this compound may be flammable, exposed to open flames, hot topics, etc., or cause combustion or even explosion. Store away from fire and heat sources, and keep well ventilated to prevent dangerous conditions.
Discuss the operating specifications, and do not prepare hastily before the experiment. Experimenters need to be familiar with the properties and latent risks of 4-Ethyliodobenzene, and carefully plan the operation process. When taking it, be careful in the fume hood, precisely control the dosage, and avoid spillage.
During operation, reaction conditions such as temperature and pressure need to be strictly controlled. Due to its reaction characteristics or strict requirements for conditions, a slight deviation, or the reaction is out of control, which not only affects the quality of the product, but may also endanger safety.
After the operation is completed, the remaining 4-Ethyliodobenzene should be properly disposed of according to regulations and must not be discarded at will. The experimental equipment should also be cleaned in time to eliminate residual substances to prevent subsequent experiments from being disturbed or causing other safety problems.
In short, the safety and operation standards of 4-Ethyliodobenzene need to be vigilant at all times and treated strictly to ensure the safety of personnel and the smooth progress of the experiment.

Application Area

4 - Ethyliodobenzene is an organic compound with a wide range of application fields. In the field of organic synthesis, it can be used as a key intermediate. For example, in the construction of complex organic molecular structures, with its unique chemical properties, it can be cleverly connected with other organic fragments through many reactions, such as coupling reactions, thus laying the foundation for the synthesis of novel compounds.
In the field of materials science, it also has potential application value. The specific materials it participates in the preparation may have unique electrical and optical properties, which can be applied to the development of new electronic devices and optical materials.
Furthermore, in the field of medicinal chemistry, through reasonable modification and transformation, it may be able to derive substances with specific biological activities, providing the possibility for the development of new drugs. Overall, 4-Ethyliodobenzene has shown important application potential in many fields, and its application prospects will become broader with the deepening of research.

Research & Development

Today, there is the name 4 - Ethyliodobenzene, which is quite important in the field of my chemical research. I have been working on the study of this thing for a long time, hoping to clarify its properties and expand its uses, in order to promote the progress of science and technology.
At the beginning, explore its structure, clarify the conformation of its molecules, and understand the connection of its atoms. Then study its chemical properties and observe its changes in various reactions. Under various conditions, observe its function with other things in detail, analyze the mechanism of its reaction, and obtain accurate conclusions.
In the research, also seek the way of development of this thing. Think of new techniques and new methods to improve its yield and quality. I hope it will be widely used in medicine, materials and other fields to benefit the world. I will make unremitting research and development of 4-Ethyliodobenzene, making great progress and contributing to the chemical industry.

Toxicity Research

Recently, I have been researching the toxicity of 4-Ethyliodobenzene, focusing on the study of its toxicity. Although this substance has been widely used in various industrial fields, its toxicity is still poorly known.
I have measured its effects on organisms by various methods. From the perspective of experimental organisms, there are behavioral and physiological changes at low concentrations. At high concentrations, the damage is more obvious, such as organ abnormalities and metabolic disorder.
Investigate its toxicology, or due to the special molecular structure, it is easy to interact with biological macromolecules and disturb its normal function. And metabolized, or produce more toxic products.
I know very well that 4-Ethyliodobenzene is extremely toxic. In the future, we should expand the breadth and depth of research, for the safety of industrial use and the protection of the environment, and make every effort to clarify its nature, avoid its harm, and seek well-being for the world.

Future Prospects

I have tried to study chemical substances, and now I focus on 4-Ethyliodobenzene. This substance has been studied to a certain extent in the field of chemistry today. Looking at its future, I am still full of expectations.
The future development may be refined in the synthesis method. Strive for a simpler, purer and more efficient method to reduce its cost and increase its yield. Furthermore, its application in materials science may have new frontiers. It may become a key component of new functional materials for electronics, optics and other fields.
And in pharmaceutical chemistry, it is also expected to emerge. Or it can be modified and derived to provide new paths for the development of new drugs. I believe that with time, 4-Ethyliodobenzene will be able to showcase its brilliance in various fields, contributing to the advancement of chemistry and science and technology, and developing infinite possibilities to feed the world.

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Frequently Asked Questions

As a leading 4-Ethyliodobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 4-ethyliodobenzene?

4-Ethyliodobenzene is also an organic compound, and its Chinese name is 4-iodoethylbenzene. Its chemical properties are quite interesting and closely related to its structure.
From its structural point of view, the benzene ring is a stable conjugated system, which endows the compound with a certain degree of aromaticity. Ethyl is connected to the benzene ring, and because it is a power supply group, it can increase the electron cloud density of the benzene ring through induction and superconjugation effects. The iodine atom is an electron-withdrawing group, which decreases the electron cloud density of the benzene ring through induction effects.
This compound can undergo many reactions. The first is the electrophilic substitution reaction. Due to the action of the power supply of ethyl group, the electron cloud density of the ortho and para-position of the benzene ring is relatively high, and the electrophilic reagents are more likely to attack the ortho and para-position. If it is used with bromine under the action of appropriate catalysts, it can generate ortho or para-brominated products. The second is a coupling reaction. The activity of iodine atoms is high. In the presence of suitable metal catalysts and ligands, it can be coupled with other organometallic reagents to form carbon-carbon bonds. This reaction is widely used in organic synthesis. Third, the hydrogen atom on the ethyl group can undergo a substitution reaction under appropriate conditions, such as under light or high temperature, it can undergo a free radical substitution reaction with halogens.
In addition, 4-ethyliodobenzene has a certain lipid solubility in organic solvents because it contains benzene ring and iodine atom. And because of its structural particularity, it may have potential applications in materials science, pharmaceutical chemistry and other fields. For example, in material synthesis, it can be used as a structural unit for constructing complex organic materials; in drug development, it can be modified by modifying its structure to regulate the activity, solubility and metabolic properties of drugs.

What are the main uses of 4-ethyliodobenzene?

4-Ethyliodobenzene, which is 4-ethyliodobenzene, has a wide range of uses and is an essential intermediate in the field of organic synthesis.
One of them can be used to construct complex aromatic compounds. In organic synthesis, it is often necessary to expand the carbon chain or introduce special functional groups. 4-ethyliodobenzene contains iodine atoms and ethyl groups, and the iodine atoms are highly active. It can undergo many reactions, such as the Suzuki reaction and coupling with boron-containing reagents to form new carbon-carbon bonds, thereby extending the carbon chain and constructing complex aromatic systems. This is of great significance in the preparation of new drugs and functional materials.
Second, in materials science, it also has important functions. It can be chemically modified to introduce it into the structure of a polymer to endow the material with special photoelectric properties. For example, when preparing organic Light Emitting Diode (OLED) materials, the special structure of 4-ethyliodobenzene may improve the charge transfer capacity and luminous efficiency of the material, and improve the performance of OLED devices.
Furthermore, in the field of medicinal chemistry, 4-ethyliodobenzene can be used as the starting material of lead compounds. After modifying and modifying its structure, new drug molecules with biological activity are explored. Due to the existence of benzene rings and substituents, it may interact with specific targets in organisms, providing a possible direction for the development of new drugs. In conclusion, 4-ethyliodobenzene, with its unique structure and reactivity, is an indispensable key substance in many fields such as organic synthesis, materials science, and medicinal chemistry, promoting research and development in various fields.

What are the synthesis methods of 4-ethyliodobenzene?

4-Ethyliodobenzene is 4-ethyliodobenzene. The common synthesis methods are as follows:
First, benzene is used as the starting material. First, benzene and acetyl chloride are acylated by Fu-gram under the catalysis of aluminum trichloride to obtain acetophenone. Acetophenone can be converted into ethylbenzene by Clemson reduction method, which is treated with zinc amalgam and concentrated hydrochloric acid. Ethylbenzene can be prepared by reacting in a suitable solvent (such as glacial acetic acid, etc.) in the presence of iodine and a suitable oxidant (such as hydrogen peroxide, etc.). 4-ethyliodobenzene can be prepared. In this process, the acylation reaction of Fu-gram is an important electrophilic substitution reaction of aromatics. The carbonyl positive ion of acetyl chloride attacks the benzene ring to form a carbon positive ion intermediate, and acetophenone is obtained by deprotonation. Clemenson's principle is to reduce the carbonyl group to methylene. Subsequent iodization reactions can promote the substitution of iodine with ethylbenzene, and because ethyl is an ortho-para-site, iodine tends to enter the para-site.
Second, p-ethylaniline is used as a raw material. P-ethylaniline and sodium nitrite undergo diazotization in hydrochloric acid medium to form diazonium salts. Subsequently, the diazonium salt is co-heated with potassium iodide solution, and the diazonium group is replaced by an iodine atom to obtain 4-ethyliodobenzene. The diazonium reaction needs to be carried out at low temperature to prevent the decomposition of the diazonium salt. The diazonium group has high activity. When reacting with potassium iodide, iodine ions act as nucleophiles to attack the diazonium group and achieve substitution.
Third, p-bromoethylbenzene is used as a raw material. Under palladium catalysis, p-bromoethylbenzene undergoes an ullman reaction with cuprous iodide and appropriate ligands (such as 1,10-phenanthroline, etc.) under basic conditions, and the bromine atom is replaced by the iodine atom to generate 4- The alkaline conditions help to stabilize the reaction intermediates and improve the reaction efficiency.
The above methods have advantages and disadvantages, and should be used according to the actual situation, such as the availability of raw materials, cost, difficulty of reaction conditions and other factors.

What are the precautions for 4-ethyliodobenzene during storage and transportation?

4 - ethyliodobenzene is also an organic compound. When storing and transporting, all kinds of precautions should not be ignored.
First, when storing, find a cool, dry and well-ventilated place. Because of its flammability, if it is at high temperature or near a fire source, it will be dangerous. The indoor temperature should be controlled within a specific range to prevent it from deteriorating or causing accidents due to excessive temperature. And it must be kept away from oxidizing agents. When the two meet, they are prone to chemical reactions, which can cause changes in the properties of compounds, or even lead to accidents. It must be sealed and stored, because moisture, oxygen, etc. in the air can interact with it and damage its quality.
As for transportation, the carrier needs professional training to be familiar with its characteristics and emergency response methods. Containers used for transportation must be sturdy and well sealed to prevent leakage. During transportation, avoid exposure to the sun, rain, and bumps in the road. If mixed with other goods, never co-load with oxidizers, acids, etc., to prevent dangerous reactions. Once a leak is detected, it should be dealt with immediately according to the established emergency plan, evacuate the crowd, seal the scene, and professionals should quickly clean it up in an appropriate way to prevent the spread of contamination.
All of these are the keys to the storage and transportation of 4-ethyliodobenzene. Practitioners must be careful to ensure safety.

What are the effects of 4-ethyliodobenzene on the environment and human health?

4-Ethyliodobenzene, or 4-ethyliodobenzene, has an important impact on the environment and human health.
In the environment, if 4-ethyliodobenzene is released into the atmosphere, it will diffuse through atmospheric circulation. Because of its volatility, it can participate in photochemical reactions. Under sunlight, or react with other substances in the atmosphere, such as hydroxyl radicals, to form new compounds. This process may change the chemical composition of the atmosphere and affect air quality. And it exists in the atmosphere, or it settles to the ground or water with precipitation and other processes.
If it enters the water body, because of its hydrophobicity, or adsorbed on suspended particulate matter, it will settle into the sediment at the bottom of the water. In the aquatic ecosystem, or cause harm to aquatic organisms. It may interfere with the physiological processes of aquatic organisms, such as affecting the respiration, feeding and reproduction of fish. If some aquatic organisms are exposed to water bodies containing 4-ethyl iodobenzene for a long time, or experience growth retardation, developmental deformities, etc., resulting in a decrease in the number and diversity of biological populations.
As for the soil environment, 4-ethyl iodobenzene may be adsorbed by soil particles after entering the soil. It may affect the activity and community structure of soil microorganisms. Soil microorganisms are crucial in soil nutrient cycling, organic matter decomposition and other processes. The presence of 4-ethyliodobenzene may inhibit the growth of certain beneficial microorganisms, hinder the normal ecological function of soil, and then affect the growth of vegetation.
For human health, 4-ethyliodobenzene can enter the human body through various routes. If people are in an environment where it evaporates in the air, they can be inhaled through the respiratory tract. Once it enters the respiratory tract, or irritates the mucosa of the respiratory tract, causing uncomfortable symptoms such as cough and asthma. Long-term inhalation may cause damage to the lungs and reduce the ventilation and ventilation functions of the lungs.
It can also enter the human body through skin contact. After skin contact with substances containing 4-ethyliodobenzene, it may cause allergic reactions to the skin, resulting in erythema, itching, blisters and other symptoms. If the skin is damaged, it is easier to enter the human blood circulation system, and then transported to various tissues and organs of the body.
After entering the human body, 4-ethyliodobenzene may undergo metabolic transformation in the body. Its metabolites or interact with biological macromolecules in the body, such as proteins, nucleic acids, etc., interfering with the normal physiological function of cells. Or there is a latent risk of mutagenesis and carcinogenesis, long-term exposure or increase the risk of cancer, seriously threatening human health.