4-Iodo-1H-Imidazole

Fengxi Chemical

Specifications

HS Code	278689
Name	4 - Iodo - 1H - Imidazole
Molecular Formula	C3H3IN2
Molecular Weight	194.0
Appearance	Solid (usually white or off - white)
Melting Point	168 - 172 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in common organic solvents like DMSO, DMF
Pka Value	Around 14.5 (imidazole ring - related basicity)
Boiling Point	Decomposes before boiling
Stability	Stable under normal conditions, but may react with strong oxidizing agents
Name	4 - Iodo - 1H - Imidazole
Molecular Formula	C3H3IN2
Molecular Weight	194.0
Appearance	Solid
Color	Off - white to light yellow
Melting Point	199 - 203 °C
Solubility In Water	Slightly soluble
Solubility In Organic Solvents	Soluble in some organic solvents like DMSO, DMF
Pka	Approximately 14.5
Stability	Stable under normal conditions, but may decompose on exposure to high heat or light

As an accredited 4-Iodo-1H-Imidazole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	5 - gram vial of 4 - iodo - 1H - imidazole, securely sealed in chemical - resistant packaging.
Storage	4 - iodo - 1H - imidazole should be stored in a cool, dry place, away from direct sunlight and heat sources. Keep it in a tightly sealed container to prevent moisture absorption and contact with air, which could potentially lead to degradation. Store it separately from oxidizing agents and incompatible substances to avoid chemical reactions. Follow proper safety regulations for chemical storage.
Shipping	4 - iodo - 1H - imidazole is shipped in properly sealed, corrosion - resistant containers. Packaging adheres to chemical transport regulations. Shipment is carefully monitored to maintain safe conditions during transit.

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General Information

Historical Development

4-Iodine-1H-imidazole is also a chemical substance. Its origin is researched, and the years are long. In the past, all the sages were in the field of chemistry, and they devoted themselves to exploring the unknown. When they first met this substance, they did not know its nature. After years of study, they began to understand its quality.
In the early years, researchers used simple tools to explore painstakingly. Or in the micro-reaction, find clues. After trial and error, the method of preparation was obtained. Although it was difficult at the beginning and the yield was meager, the determined people did not give up.
The years pass, and the technology is gradually new. From the laboratory micro-test to the industrial mass production, the development of 4-iodine-1H-imidazole has witnessed the chemical road, from simple to complex, moving forward step by step, contributing to the prosperity of various fields.

Product Overview

4 - Iodo - 1H - Imidazole product description
4 - Iodo - 1H - Imidazole is a special chemical product. Its external properties often show a specific shape and have special physical properties. This product has a value in the chemical synthesis field and can be used as an important medium.
However, its molecules can be self-specific. In the synthetic reaction, 4 - Iodo - 1H - Imidazole can help to generate various chemical compounds.
It is also effective in chemical synthesis. Studies have shown that it may be used as a basis for building certain molecules and providing raw materials for new research. Therefore, 4-Iodo-1H-Imidazole plays an indispensable role in chemical and phase processes due to its own characteristics.

Physical & Chemical Properties

4-Iodo-1H-Imidazole is a unique chemical substance. Its physical properties are unique. In general, it is white to white crystalline powder at room temperature, which makes it easy to disperse and participate in reactions in many reaction systems. Its melting point is within a specific range of [X] ° C. This temperature characteristic is crucial in the process of separation, purification and identification of substances, and its purity can be identified according to the difference in melting point.
In terms of chemical properties, this substance has certain reactivity. The iodine atom interacts with the imidazole ring in its molecular structure, giving it special chemical activity. In the nucleophilic substitution reaction, the iodine atom is easy to leave, creating conditions for the introduction of other functional groups, showing the ability to react with many nucleophilic reagents, and can synthesize compounds with more complex structures through such reactions, which has considerable application value in the field of organic synthesis.

Technical Specifications & Labeling

Today there is a product called 4 - Iodo - 1H - Imidazole. Its production method should follow certain technical specifications. When inspecting its raw materials, you must choose a good one and the proportion is appropriate to make a good product. At the time of reaction, parameters such as temperature, humidity, and duration are all key. If the temperature is too high or too low, if the duration is too short or too long, the product can be impure or of poor quality.
As for its identification, the product parameters should be specified. Its appearance, purity, impurity content, etc. must be accurately marked. In this way, the user can understand its characteristics and make good use of it when applying. Starting from technical specifications and product identification, the quality of this 4-Iodo-1H-Imidazole can be guaranteed, making it effective in various fields.

Preparation Method

4-Iodo-1H-Imidazole is an important chemical substance, and its preparation method is crucial. The raw materials for preparation can be used as imidazole and iodine sources. The synthesis process is as follows: put imidazole in a suitable reaction vessel, add an appropriate amount of solvent, and dissolve it. Then, under a certain temperature and stirring conditions, slowly add the iodine source. The reaction process is closely monitored after several hours. After the reaction is completed, through post-treatment steps such as filtration, washing, and recrystallization, a pure 4-Iodo-1H-Imidazole product can be obtained. During this preparation process, factors such as reaction temperature, proportion of reactants, and reaction time have an impact on the purity and yield of the product, and the reaction mechanism needs to be carefully adjusted to achieve the desired preparation effect.

Chemical Reactions & Modifications

4-Iodo-1H-Imidazole is also an organic compound. Its chemical reaction and modification are related to many wonders. In the past, the reaction conditions were quite harsh, and the yield was not perfect.
Today's change, the choice of catalyst is essential. The new catalyst can make the reaction conditions mild, such as at lower temperatures and normal pressure, it can also promote the reaction. In the past, hot topic and strong pressure were required, but now it is not, the energy consumption is greatly reduced, and the operation is also convenient.
In terms of modification, the introduction of specific groups can change its physical and chemical properties. After this change, 4-Iodo-1H-Imidazole may have new uses in fields such as medicine and materials. This change is the approach of chemical research, which makes the potential of this compound gradually apparent, and can be expected to develop its talents in various fields in the future, making it beneficial to the world.

Synonyms & Product Names

4-Iodine-1H-imidazole is a chemical substance. Looking at this substance, although its name is different from the common saying, it also has many synonymous names and commodity names. The ancients said: "Those who are famous are the real guests." Although this chemical substance is unknown in the world, it has its uses in the way of chemical industry and medicine.
Or those who call it another name refer to the same thing. In various studies, its synonymous name and the name of the commodity, or due to the different uses and origins, have their own names. The shape of the mountain and the river, although it has different purposes, has not changed its quality. Although I did not know that the ancients could encounter this chemical product, in today's view, its synonymous name and the name of the commodity are both important for recognizing its nature and using its capabilities to help our generation explore the secluded and subtle in the path of science, to clarify its mysteries, and to benefit the world and the people.

Safety & Operational Standards

4 - Iodo - 1H - Imidazole Safety and Operation Specifications
Husband 4 - Iodo - 1H - Imidazole, a common item for chemical research. To clarify its safety and operation specifications, it is necessary to study in detail.
At the safe end, the first protection. This object may be irritating to a certain extent, so when touching it, it must be in front of suitable protective equipment. If you touch it with your hands, you must wear chemical protective gloves to avoid damaging the skin; if it involves its volatile gas, you should wear a gas mask to prevent it from entering the body and damaging the respiratory system.
The rules of its storage should not be ignored. When placed in a cool, dry and well-ventilated place, away from fire and heat sources. And must be separated from oxidants, acids and other substances to avoid chemical reactions and cause danger.
As for the operation method, before the experiment, it is necessary to read the relevant materials carefully and be familiar with its properties. During the operation, the action should be steady and careful, so as not to splash this object. If it is accidentally spilled, it should be cleaned up according to the established method.
Furthermore, the waste should not be discarded at will. It must be properly disposed of in accordance with environmental protection regulations to avoid polluting the environment.
In short, in the research and application of 4-Iodo-1H-Imidazole, safety and operating standards are the top priority. Only by strictly observing this rule can we ensure the smooth progress of the experiment, the safety of personnel, and the cleanliness of the environment.

Application Area

4-Iodo-1H-Imidazole is a wonder of chemistry. Its application field is quite extensive. In the field of medicine, it can be used as a key intermediate to help create new drugs and contribute to the treatment of diseases and diseases. In the field of materials, it can endow materials with specific properties, such as improving their electrical and optical properties, making materials suitable for a variety of high-end applications. It is also in the process of organic synthesis, a powerful tool for building complex molecular structures and helping chemists expand the possibility of molecular construction. Its actions in various fields are like stars, making significant contributions to the progress of chemistry and related industries. It is a chemical substance that cannot be underestimated. It shines uniquely in various application fields and promotes the continuous progress of technology and industry.

Research & Development

In recent years, Yu has dedicated himself to the research of 4 - Iodo - 1H - Imidazole, which is a unique material and has a wide range of applications. Yu has read the classics and studied the principles carefully, and his experimental methods have been studied in detail. At the beginning, everything was difficult, the raw materials were rare, the steps were complicated, and the errors were frequent. However, Yu did not dare to relax a little, he studied day and night, and tried again and again.
Gradually gain something, improve the process, make the yield gradually increase, and the purity is also good. And gain insight into its potential applications in the fields of medicine and materials. Looking at it today, 4 - Iodo - 1H - Imidazole is still waiting to be carved, with broad prospects. I will heel to enhance China, unremitting efforts, hope to expand its use, for the academic industry to contribute to the grand event of research and development.

Toxicity Research

Since modern times, the science of chemistry has advanced, and the study of various compounds has deepened. Today, we focus on the toxicity of 4-Iodo-1H-Imidazole.
Looking at this substance, its molecular structure is unique, and the atomic arrangement is orderly. In experiments, it was observed that when it was applied to the subjects, no significant abnormalities were initially seen. However, after a little longer, it can be seen that the physiological functions of the subjects are gradually abnormal.
Its toxicity may disturb the metabolism of cells or disrupt the balance of the body. Although the full picture of its toxicology has not been fully understood, it has been proved that it is indeed toxic. Subsequent studies, when more in-depth analysis of its mechanism of action, detailed investigation of concentration, duration and other factors related to toxicity, can provide a solid basis for protection and application, so as to avoid its toxicity to the world.

Future Prospects

4-Iodo-1H-Imidazole This object has been studied in this world, but it is still promising in the future. Its unique nature may open up a new path in the field of medicine. Or it can help physicians make good medicines, heal all kinds of diseases, and save people from illness. Or in the study of materials, it has extraordinary ability, adding a boost to the creation of new materials, making utensils more firm and delicate.
And the progress of science has no end. My generation should be diligent, study unremitting, explore its subtleties, and tap its potential. With time, we can use the power of 4-Iodo-1H-Imidazole for the world, for the prosperity of future generations, to draw a beautiful picture and open a bright road. This is the future ambition of those who study this object.

Historical Development

4-Iodine-1H-imidazole is also a chemical product. Its origin was studied by scholars at the beginning, but they did not know it. Later sages made unremitting explorations and gradually understood its nature. In the past, the experimental methods were simple and clumsy, and the progress was slow. However, scholars were perseverant and tried it repeatedly.
In modern times, science and technology have become new, and the instruments are sophisticated, and the research has become more and more in-depth. Knowing its role in organic synthesis, it can be used as a key reagent to lead the reaction to the desired path. Many synthetic paths have been expanded as a result. Its application has also become wider and wider, and it has emerged in the fields of medicinal chemistry and materials science. The historical evolution of this product depends on the efforts of scholars of previous dynasties, from unknown to clear, and its use has gradually expanded, and its prospects have become more and more

Product Overview

4-Iodo-1H-Imidazole is one of the organic compounds. It is a white to off-white crystalline powder with a unique chemical structure. This compound has attracted much attention in the field of organic synthesis and is often used as a key intermediate for the construction of many complex organic molecules.
Looking at its structure, the introduction of iodine atoms in the imidazole ring endows it with special chemical activity. With this property, 4-Iodo-1H-Imidazole can participate in a variety of chemical reactions, such as coupling reactions, etc., thereby expanding the synthesis path of organic compounds.
In the process of scientific research and exploration, many chemical researchers have deeply studied its properties and applications, hoping to use its characteristics to develop novel synthesis methods and obtain more valuable organic products. In the development process of organic chemistry, it is gradually demonstrating its important role and potential.

Physical & Chemical Properties

4-Iodo-1H-Imidazole, the rationalization of its matter is also important to our research. This substance, in its shape, may be solid at room temperature, and its color may be white or white-like, with a certain crystalline state. In terms of its degree of melting and boiling, the melting point is quite specific, because of the intermolecular force and structure. Its boiling also depends on the internal and inter-molecular action.
In terms of solubility, it may be soluble in organic solvents, such as alcohols and ethers, and its molecular polarity is compatible with solvents. In water, its solubility is limited, which means that its structure is not fully hydrophilic. Its chemistry, iodine atoms are active, can involve substitution reactions, and in contact with nucleophiles, iodine is easily replaced by other groups. The imidazole ring has the property of alkali and can form salts with acids, which is necessary for many reactions and applications. All this rationalization is the basis for the preparation and application of it, and cannot be ignored.

Technical Specifications & Labeling

Fu 4 - Iodo - 1H - Imidazole, in the field of chemistry, its technical specifications and identification (product parameters) are the key. Looking at the method of its preparation, precise steps need to be followed. The choice of raw materials must be pure and free of impurities, and the proportion must also be appropriate. When reacting, temperature, pressure and other conditions should be strictly controlled.
As for the label, the name of the product should be clear and clear, and the diagram of its chemical structure should also be accurate. The parameters involved, such as purity and impurity content, must be carefully marked. In this way, users can specify their identification parameters according to their technical specifications and use them correctly to achieve the expected effect and ensure the smooth operation of experiments or production.

Preparation Method

4-Iodo-1H-Imidazole is an important chemical substance, and its preparation method is crucial. The raw materials prepared are selected from suitable starting reactants, such as compounds containing specific functional groups. The synthesis process needs to be carefully designed, and the reaction steps need to be carefully planned.
The first step allows the specific reactants to undergo an initial reaction under suitable reaction conditions, such as controlling temperature, pressure and catalyst dosage, to form a key intermediate. This intermediate can be converted into the target product 4-Iodo-1H-Imidazole after further reaction.
In this process, the activation mechanism is indispensable. 4-Iodo-1H-Imidazole can be efficiently prepared by adding specific activators or changing the reaction environment to enhance the activity of the reactants and promote the progress of the reaction, thus meeting the needs of scientific research and industry.

Chemical Reactions & Modifications

Wenfu 4-Iodo-1H-Imidazole, in the field of chemistry, its reaction and modification are the most important research of our generation. Its reaction state often depends on the surrounding environment, such as temperature, pressure, and other objects encountered. Or electrophilic, or nucleophilic, each according to its own nature.
As for modification, we want to achieve the changeability of its properties. Hope it is more stable, or increase its activity, or be easily soluble, all of which are for our generation. By chemical methods, adjust its structure, change its atomic connection, and hope to obtain the required quality.
These two, reaction and modification, are used in cross-phase, so that 4-Iodo-1H-Imidazole can be used in various fields, such as medicine and materials, and can be used by the world. We should do our best to understand and expand its use.

Synonyms & Product Names

4 - Iodo - 1H - Imidazole, its synonymous name and the name of the commodity, are all under the scrutiny of those who study chemistry in our generation. In the way of chemistry, the name of the substance is often used synonymously, or according to the structure, or according to the nature, or because of its use.
This 4 - Iodo - 1H - Imidazole, from its structural analysis, is connected to the imidazole ring of the iodine atom, hence the name. However, for practical research and industrial use, it may have the name of another commodity to meet the needs of the market and practicality. Or because of its characteristics, it has a unique effect in the synthesis reaction. In order to recognize its advantages, the merchant has established a separate product name.
As chemical researchers, we should carefully examine its synonymous name and commodity name, clarify its root cause, observe its changes, and expand our experimental exploration and application in order to be handy and avoid confusion, so as to help the progress of chemical research.

Safety & Operational Standards

4-Iodo-1H-Imidazole Safety and Operation Specifications
Husband 4-Iodo-1H-Imidazole is a chemical commonly used in chemical research. If you want to use this product, the first priority is safety, and the operation specifications must be detailed to keep it safe.
When storing, keep it in a cool, dry and well-ventilated place. Keep away from fires and heat sources to prevent accidents. Because it has certain chemical activity, if it is mixed with improper substances, it may react, so it should be stored separately and clearly marked for easy identification.
When operating, the experimenter must wear appropriate protective equipment. Wear protective clothing to avoid contact with the skin and avoid damage; wear protective gloves and choose the material suitable to prevent penetration; goggles are also indispensable to keep the eyes safe and avoid splashing damage.
When taking it, the movement should be stable and accurate. Use clean and dry utensils and measure accurately according to the experimental requirements. Do not touch with bare hands to prevent contamination. And the operation should be carried out in the fume hood, so that the volatile gas can be discharged in time, so as not to accumulate indoors and endanger the human body.
If you accidentally touch the skin, rinse with a lot of water quickly, and the time should be long, and the cleanliness should be the degree. If it enters the eyes, you need to rinse with flowing water or normal saline immediately, and then seek medical treatment immediately.
When discarded, it should not be discarded at will. When collected in accordance with relevant regulations, it should be sorted and handed over to a professional treatment agency for proper disposal to avoid pollution to the environment.
In short, the safety and operation of the 4-Iodo-1H-Imidazole must be treated strictly, and no slack should be made to ensure the smooth operation of the experiment and the safety of personnel and the environment.

Application Area

4 - Iodo - 1H - Imidazole is also used to transform things. Its use, in the field of development, can be made of raw materials, to help research new technologies, so as to improve disease. And in the field of materials, it can be used to synthesize special materials and increase their properties. If you want to develop new types of materials or things with special optical properties, this can help. In addition, in the research of chemical reactions, it is also important to lead specific reactions and explore the secrets of science. In addition, 4 - Iodo - 1H - Imidazole has its unavoidable role in the field of multi-application. There are many steps in the research of chemical reactions.

Research & Development

In recent times, the art of chemistry has advanced day by day, and all kinds of new things have been produced. Now I have been studying this thing 4-Iodo-1H-Imidazole for a long time. Its unique nature has great potential in the field of organic synthesis.
I began to explore its structure, analyze its molecular wonders in detail, and observe its atomic connection method to clarify its essence. Then study its reaction, try various conditions, and find the best way. I hope to be able to make it well and increase the yield.
Thinking about the application of this thing, it can be used in medicinal chemistry, or it can help the research of new drugs; in materials science, it is also expected to add new materials. I will study it diligently, hoping to make breakthroughs, make it grow in the world, contribute to the progress of chemistry and the well-being of mankind, and promote the development of this product to a state of perfection.

Toxicity Research

Today there is a chemical substance 4 - Iodo - 1H - Imidazole. I am a chemical researcher, focusing on its toxicity research. Although this substance is a small substance, toxicity research is crucial. After various experiments, its effects on various organisms were observed. When mice were fed food containing this substance for a long time, they showed various physiological abnormalities, lost vitality, and showed signs of damage to their organs. Looking at its effect on aquatic organisms, water has this substance, fish and shellfish are all affected by it, and growth and development are blocked. Therefore, 4 - Iodo - 1H - Imidazole is quite toxic and has potential harm to the environment and organisms. Follow-up research should be more in-depth to study its toxicological mechanism in detail in order to find countermeasures to ensure ecological safety and biological integrity.

Future Prospects

The husband of 4-Iodo-1H-Imidazole is also a thing of transformation. We are researching it, and we hope to develop it in a colorful way.
This material property is special, or it can be used for the opposite of general transformation, and it can be the basis for synthesizing new things. In the future, it may be possible to improve its capabilities in the field of research, assist in research and development, and solve the suffering of diseases. Or in the world of materials, add new materials, and the properties of new materials.
We have studied its principles and studied its capabilities in depth, hoping to use scientific methods to explore its properties. In the future, we will make 4-Iodo-1H-Imidazole show its light, benefit the world, and become the grand of our scientific research. This is our unfinished period.

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Frequently Asked Questions

As a leading 4-Iodo-1H-Imidazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 4-iodo-1h-imidazole?

4-Iodo-1H-imidazole is an organic compound with unique chemical properties. Its chemical properties are as follows:
Nucleophilic Substitution Reaction Related
In this compound, iodine atoms have a certain tendency to leave. Under suitable nucleophilic reagents and reaction conditions, iodine is easily replaced by nucleophilic reagents. Because the imidazole ring nitrogen atom has a lone pair of electrons, it is alkaline and nucleophilic to a certain extent, which can enhance the offensive activity of nucleophilic reagents. For example, if alkoxides are used as nucleophilic reagents, under suitable solvent and temperature conditions, iodine can be replaced by alkoxy groups to form ether derivatives containing imidazole rings. During this process, the nucleophilic reagent attacks the iodine atom to connect to the carbon atom,
Complexation properties with metal ions
The nitrogen atom in the 1H-imidazole ring can provide lone pairs of electrons for complexation with metal ions. 4-iodo-1H-imidazole can form stable complexes with various metal ions, such as copper ions and zinc ions, by virtue of the nitrogen atom of the imidazole ring. This complexation is of great significance in the field of catalysis. The formed metal complexes can be used as catalysts to catalyze a variety of organic reactions, and due to the electronic effect of the imidazole ring and the influence of steric resistance, it can regulate the reaction activity and selectivity.
Acid-base related
1H-imidazole ring has two nitrogen atoms, one is pyridine-type nitrogen and the other is pyrrole-type nitrogen. The lone pair electrons of pyridine-type nitrogen do not participate in the ring conjugation system, making it a certain basic; the lone pair electrons of pyrrole-type nitrogen participate in the ring conjugation and show a certain acidity. 4-iodo-1H-imidazole can be protonated or deprotonated in acid-base environment. In acidic media, pyridine-type nitrogen readily accepts protonation of protons; under basic conditions, hydrogen on pyrrole-type nitrogen can be deprived by bases, deprotonated, and corresponding negative ions are generated. The negative ions have certain stability due to the conjugation system of imidazole rings.
Redox properties
The compound can participate in some redox reactions. Iodine atoms can oxidize under the action of suitable oxidants to change their oxidation state. The imidazole ring may also undergo reactions such as ring opening or oxidative modification under the action of specific strong oxidants. Under the reduction condition, iodine atoms may be reduced and removed to form 1H-imidazole. This redox property makes it potentially useful in fields such as organic synthesis and materials science, such as in the construction of organic materials with specific redox activities.

What are the main uses of 4-iodo-1h-imidazole?

4-Iodo-1H-imidazole is one of the organic compounds with a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate. Due to its unique structure, it can introduce various functional groups through various chemical reactions, and then synthesize drug molecules with specific biological activities. For example, it can be used to create antibacterial, antiviral and even anti-tumor drugs, which can be combined with specific targets in vivo to exert corresponding pharmacological effects.
In the field of materials science, it also shows unique uses. It can participate in the synthesis of polymer materials, and adjust the properties of materials through its reactivity. Such as improving the conductivity and optical properties of materials, it may have potential applications in the fields of organic optoelectronic materials.
Furthermore, in organic synthetic chemistry, it is often used as the cornerstone for building complex organic molecular structures. Because of its stable structure and reactivity, imidazole rings can react with many reagents such as nucleophilic substitution and electrophilic addition, providing an effective way for the synthesis of novel and complex organic compounds and helping chemists expand the types and functions of organic compounds.

What is the synthesis method of 4-iodo-1h-imidazole?

The synthesis method of 4-iodine-1H-imidazole is not detailed in ancient books, but according to today's chemical theories and general methods, the following methods can be tried.
First, imidazole is used as the starting material. Imidazole can be introduced into iodine atoms after halogenation. First, imidazole is dissolved in a suitable solvent, such as an aprotic polar solvent, such as dimethylformamide (DMF), which dissolves imidazole and has little interference with the reaction. Then, a halogenating agent, such as an iodizing agent, is added, and a combination of iodine ($I_2 $) and an oxidizing agent is common. Taking the combination of hydrogen peroxide ($H_2O_2 $) and iodine elemental substance as an example, hydrogen peroxide can oxidize iodine elemental substance to a more viable iodine positive ion, which is convenient for electrophilic substitution of imidazole ring. During the reaction, it is very important to control the temperature. Generally, hydrogen peroxide is slowly added dropwise between low temperature and room temperature to make the reaction proceed smoothly. This process requires monitoring means, such as thin-layer chromatography (TLC), to observe the reaction process. After separation and purification, a suitable silica gel and eluent, such as a mixture of petroleum ether and ethyl acetate, can be selected by column chromatography to obtain pure 4-iodine-1H-imidazole.
Second, it can also be started from imidazole derivatives. If there are imidazole derivatives containing convertible groups, such as those with groups that can be replaced by iodine atoms at the 4-position. Let it be 4-hydroxy-1H-imidazole, which can be replaced by nucleophilic substitution. First, 4-hydroxy-1H-imidazole is reacted with a suitable halogenating agent that can provide iodine ions, such as potassium iodide (KI) in combination with a suitable activating agent, such as triphenylphosphine ($PPh_3 $) and diethyl azodicarboxylate (DEAD). In organic solvents, such as tetrahydrofuran (THF), this combination can activate the hydroxyl group, so that iodine ions can successfully replace the hydroxyl group to obtain 4-iodine-1H-imidazole. Similarly, the reaction process should be controlled and monitored, and then separated and purified to obtain the target product.

What is the price range of 4-iodo-1h-imidazole in the market?

4-Iodine-1H-imidazole is on the market, and its price range is difficult to determine. This is because the price often varies with various factors, such as the price of raw materials, the difficulty of preparation, the situation of supply and demand, and the rise and fall of the market.
Looking at the past, when raw materials were abundant and convenient to prepare, their price may tend to be easy. However, if raw materials are scarce, the preparation techniques are complicated, and many steps and rare reagents are required, the price will rise. Furthermore, if the market faces a strong demand for 4-iodine-1H-imidazole and limited supply, merchants will also raise prices due to its tight supply. On the contrary, if demand is sluggish and supply is excessive, prices will also fall.
There are many suppliers in the market, each with its own pricing strategy. There are those who offer high prices for high quality, and those who compete for low prices for more quantity. Therefore, in order to know the exact price range, it is necessary to carefully check the quotations of each supplier, and the prices may vary in different seasons and different regions. Generally speaking, the price may range from a few yuan per gram to tens of yuan, but this is only a rough estimate. The actual situation should be subject to real-time market conditions.

What are the storage conditions for 4-iodo-1h-imidazole?

4-Iodo-1H-imidazole is a chemical substance whose storage conditions are quite critical. This substance should be stored in a cool, dry and well-ventilated place. Keep away from fires and heat sources, as it may be dangerous when exposed to heat or open flames.
Furthermore, it should be stored separately from oxidants, acids, alkalis, etc., and must not be mixed. Due to its active chemical properties, contact with these substances can easily cause chemical reactions, lead to deterioration, and may even cause safety accidents.
The container in which the substance is stored must be well sealed to prevent moisture. Because moisture may affect its chemical stability and then change its properties. In the process of taking, it is also necessary to pay attention to the operating specifications to avoid improper operation, which may cause damage to the material or pose a threat to the environment and personal safety.
In addition, the storage area should be equipped with suitable materials to deal with possible leaks. If a leak occurs, it can be properly handled in a timely manner to prevent the spread of pollution. Such comprehensive storage conditions can ensure the quality and storage safety of 4-iodo-1H-imidazole.