4 Iodo 1h Indazole
Iodobenzene

4-Iodo-1H-Indazole

Fengxi Chemical

    Specifications

    HS Code

    537315

    Chemical Formula C7H5IN2
    Molecular Weight 244.03
    Appearance Solid
    Color Off - white to light yellow
    Melting Point 165 - 169 °C
    Solubility In Water Poorly soluble
    Solubility In Organic Solvents Soluble in some organic solvents like DMSO, DMF
    Purity Typically high - purity (e.g., 95%+)
    Odor Odorless or very faint odor
    Stability Stable under normal conditions, avoid strong oxidizing agents
    Chemical Formula C7H5IN2
    Molecular Weight 244.03 g/mol
    Appearance Solid (usually off - white to light yellow)
    Solubility Soluble in some organic solvents like DMSO, DMF
    Melting Point Approximately 155 - 159 °C
    Purity Can be obtained in high purity, e.g., 95%+
    Odor Odorless or very faint odor
    Stability Stable under normal conditions, but sensitive to light and air over time
    Hazard Class May be harmful if swallowed, inhaled or in contact with skin

    As an accredited 4-Iodo-1H-Indazole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 10 grams of 4 - iodo - 1H - indazole packaged in a sealed, labeled vial.
    Storage 4 - iodo - 1H - indazole should be stored in a cool, dry place, away from heat sources and direct sunlight. Keep it in a tightly - sealed container to prevent moisture absorption and exposure to air, which could potentially lead to degradation. Store it separately from incompatible substances, such as strong oxidizing agents or bases, in a well - ventilated area dedicated to chemical storage.
    Shipping 4 - iodo - 1H - indazole is shipped with strict adherence to chemical safety regulations. It is carefully packaged in appropriate containers to prevent breakage and leakage, and transported via approved carriers for safe delivery.
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    4-Iodo-1H-Indazole
    General Information
    Historical Development
    4-Iodo-1H-Indazole is a special chemical product. Looking back to the past, since the beginning of chemical research, researchers have been dedicated to the exploration and study of various compounds. At that time, science and technology were still unknown, and research methods were extremely limited.
    However, with unremitting efforts and keen insight, scholars gradually opened the door to the mystery of chemical substances. For 4-Iodo-1H-Indazole, although only a glimpse of its properties was given in the early days, it planted the seeds for subsequent research.
    With the passage of time, technology has changed with each passing day, analytical methods have become more accurate, and experimental equipment has become more advanced. Many chemists have devoted themselves to this, in-depth analysis of its structure and characteristics. Every experimental improvement and every theoretical revision has promoted the expansion of the understanding of 4-Iodo-1H-Indazole. From a vague understanding to a gradually clear understanding, the historical evolution of this chemical product is like a slowly unfolding picture, witnessing the vigorous development and unremitting pursuit of chemical research.
    Product Overview
    4-Iodo-1H-Indazole is a key compound involved in the research of pharmaceuticals. Its shape is fine crystalline, its color is nearly pure white, and it is quite stable under normal conditions.
    This compound has a unique structure. The structure of indolazole is supplemented by iodine atoms at the 4 position. This special structure endows it with different physical and chemical properties. In organic solvents, it exhibits good solubility and is easy to participate in transformation in various reaction systems.
    In terms of its application, it has extraordinary potential in the field of new drug creation. After experimental investigation, it has significant affinity for specific targets, which is expected to provide a new opportunity for the treatment of certain difficult diseases. Although the synthesis process has gone through many steps, with precise reaction regulation and purification techniques, higher purity products can be obtained, paving the way for subsequent research.
    Physical & Chemical Properties
    4-Iodo-1H-Indazole, its physical and chemical properties can be particularly investigated. Looking at its shape, it often shows a specific state, or is crystalline, color or plain, which is related to the order of its molecular arrangement. Its melting and boiling point is also characteristic, and it melts when heated, and boils when it reaches a certain temperature, which is determined by the intermolecular force. In terms of solubility, it is soluble in some solvents, but not in others. This involves the interaction between molecules and solvents. And its chemical activity is also considerable, and it can react with various reagents. Because of the specific groups in its structure, it has a unique chemical behavior. In the field of organic synthesis, it can be used as a key intermediate, causing such wonderful changes, adding a lot of opportunities for chemical exploration.
    Technical Specifications & Labeling
    Today there is a thing called 4-Iodo-1H-Indazole. The technique of its preparation requires a fine method. First, prepare all kinds of raw materials, the quantity must be accurate, and there must be no error. In clean vessels, at a suitable temperature, control all reactions. In the meantime, observe the change of its color and texture. If the temperature is high, it is easy to produce impurities, and if the temperature is low, it should be slowed down. All need careful care.
    As for the distinction of quality, the first thing to look at is its color, it should be pure, and there should be no variegated color. The second time you observe its state, it should be in line with the expected shape. Use an instrument to measure its quality and verify the proportion of its components, so as to conform to the set standard. The amount of impurities must be minimal to be a good product. By practicing this technique and distinguishing method, and strictly observing the standard, we can make good things to meet all needs.
    Preparation Method
    There is now a method for making 4 - Iodo - 1H - Indazole, which is described in detail as follows. The raw materials need to be carefully selected and taken in a certain ratio. The production process involves first reacting the raw materials in a certain way, and going through various steps. First take [specific raw materials 1] and [specific raw materials 2], fill them with appropriate equipment, and promote their fusion reaction at a specific temperature. When the reaction reaches a certain level, add [raw materials 3] in sequence to adjust the reaction rate and environment. In this process, the rhythm and temperature of the reaction need to be precisely controlled. As for the catalytic mechanism, use [catalyst name] to promote the reaction speed. The dosage and timing of addition are related to success or failure. After many debugging and fine operation, the 4-Iodo-1H-Indazole product can be obtained. Its quality and quantity depend on the exquisite production process and the fit of each link.
    Chemical Reactions & Modifications
    The wonders of chemistry are related to the change of substances, and the reaction and modification are particularly important. The study of the chemical reaction and properties of 4-Iodo-1H-Indazole is of great significance.
    In the process of reaction, it may be possible to use various reagents to make new products. If a certain agent is used to promote it, its functional groups can be translocated, its structure can be reorganized, or it can produce strange effects. Catalytic substances can also be added to increase the speed of reaction, reducing energy consumption and increasing yield.
    As for the change of properties, or the adjustment of its crystal form, resulting in physical changes and increased stability. Or introduce new groups, endowing them with special properties, such as photoelectric energy and biocompatibility.
    This is what chemical researchers have been thinking about and seeking, hoping to use microscopic research to open up a new way of material change, which is used by the world.
    Synonyms & Product Names
    4 - Iodo - 1H - Indazole This product has the same trade name, which is important for research. We need to clearly check its name in the research. 4 - Iodo - 1H - Indazole may also have different properties, as in the general report, or because of its use and method. However, it does not refer to this specific compound.
    In the field of chemistry, the same product can help researchers to communicate with each other, and the trade name is involved in commercial and circulation. This 4 - Iodo - 1H - Indazole, under what name, has its specific chemical use. We shall study the reasons for their names in order to better understand their status in chemical research and application. In this way, we can take a step further in the process of chemical research and gain a more transparent understanding of this compound.
    Safety & Operational Standards
    4 - Iodo - 1H - Indazole Product Safety and Operation Specifications
    Husband 4 - Iodo - 1H - Indazole is an important substance for chemical research. When it is experimentally operated and used, safety regulations are of paramount importance.
    #1. Storage Regulations
    4 - Iodo - 1H - Indazole should be placed in a cool, dry and well ventilated place. Keep away from fire and heat sources to prevent it from changing its properties due to heat or even causing danger. The storage place should use explosion-proof lighting and ventilation facilities to avoid potential dangerous factors such as static electricity. Do not mix with oxidants, acids, alkalis and other substances. Due to its active chemical properties, it may cause chemical reactions and endanger safety when it encounters various substances.
    #2. The essentials of operation
    Operators must be specially trained and well versed in the operation process and safety knowledge. When operating, wear protective clothing, protective gloves and goggles to protect the body from harm. When taking 4-Iodo-1H-Indazole, the movement should be gentle and avoid dust to prevent its powder from being inhaled into the human body and damaging health. If you accidentally come into contact with this object during the experiment, if it touches the skin, you should immediately rinse it with a large amount of flowing water; if it splashes into the eyes, you need to quickly rinse it with normal saline and seek medical treatment in time.
    #3. Emergency response
    In the event of a leakage accident, first of all, you should quickly evacuate the personnel in the leakage contaminated area to a safe area, and isolate them, strictly restricting personnel from entering and leaving. Emergency responders need to wear self-contained positive pressure breathing apparatus and chemical protective clothing, and do not let the leakage come into contact with the body. For a small amount of leakage, a clean shovel can be collected in a dry, clean, covered container; if the leakage is large, a dike should be built or dug for containment, covered with foam, to reduce steam disasters, and then properly disposed of.
    In short, in the research and use of 4-Iodo-1H-Indazole, strict adherence to safety and operating standards can ensure the smooth operation of the experiment, and ensure the safety of personnel and the environment.
    Application Area
    Today, there is a product called 4-Iodo-1H-Indazole, which is widely used in various fields. In the field of medicine, it may assist in the development of new drugs to treat various diseases. Due to its unique structure, it can interact specifically with biomolecules in the body and adjust the function of the body.
    In materials science, it can also be used. It can be used as a key component to make materials with special properties, such as those with excellent electrical conductivity or optical properties, to meet the needs of the electronic and optical industries.
    Furthermore, in the field of chemical synthesis, it is often an important intermediate. Chemists use it to derive a variety of compounds, expand the variety of chemical substances, and open up new avenues for scientific research and industrial production. This is all done by 4-Iodo-1H-Indazole, and its wide application and broad prospects are truly eye-catching.
    Research & Development
    Today there is a thing, named 4-Iodo-1H-Indazole. We are committed to studying its essence and properties, hoping to gain new knowledge in the field of science and promote its progress.
    At first, observe its shape, observe its state, and know its physical characteristics. Then explore its chemical properties, and find its laws of change in various reactions.
    Study this substance, not only to understand it, but also to understand why it is. Expect to use the knowledge obtained, expand its use, and help it progress. Make this substance in medicine, materials, and other industries, so that it can show its work and make its use, so as to benefit the world, promote the prosperity of science, and the progress of technology. In this way, the research will be fruitful, and there is hope for progress.
    Toxicity Research
    The toxicity of 4-Iodo-1H-Indazole is related to the health of people's livelihood, so how can we not be careless. I study things carefully. Observe its shape and quality, and observe its changes in detail. With the rigor of ancient methods, set up all kinds of tests, observe its response to things. Observe the signs of its entry into the body, either in the viscera or in the meridians, and record its state in detail. Although it has not been long, it has begun to gain. The appearance of toxicity, whether slow or urgent, needs to be studied carefully. I will diligently continue to understand the full picture of the toxicity of 4-Iodo-1H-Indazole, hoping to be used by the world, to avoid its harm and pursue its benefits, to protect all living beings on the path of health, to live up to what they have learned, and to study unremittingly.
    Future Prospects
    Looking at 4-Idoc-1H-Indazole today, it has a promising future in the field of chemical industry. Although it is only emerging at the moment, it is already evident that it will expand in the future.
    Due to the increasing technology and advanced research and development, this compound may shine in various fields such as pharmaceutical creation and material innovation. Medicine alone may be a good medicine for healing diseases; the road of materials can also become the cornerstone of innovation and breakthrough.
    Our chemical researchers, with lofty ambitions, should devote themselves to their research. With time, we will be able to make 4-Idoc-1H-Indazole play its ultimate effectiveness, seek well-being for future generations, and pave a bright path ahead in the unfinished road, develop infinite possibilities, and create extraordinary achievements.
    Historical Development
    The husband of 4-Iodo-1H-Indazole is also a thing of transformation. Its initial exploration is the result of the research of the chemical family. In the past, many people have been exploring in the field of transformation, hoping to obtain new things in order to explore the frontier of knowledge.
    At the beginning, the synthesis of this thing is unknown. With wisdom and perseverance, many methods, and many times, we have begun to have an idea. From the beginning of the rough knowledge, to the end of the study of its characteristics and the method of synthesis, the month of mulberry.
    The synthesis of its synthesis has also been changed and refined. The complex and inefficient method at the beginning, the easy and efficient way to the world, every step is the hard work of the chemical family. In this way, 4-Iodo-1H-Indazole occupies a place in the history of transformation, promoting the process of transformation research and the development of the field.
    Product Overview
    Today there is a thing called 4-Iodo-1H-Indazole. It is a key substance in chemical inquiry. Looking at its shape, it has a unique structure. This structure is like a delicate blueprint that determines its characteristics and functions.
    This substance is widely used in the field of chemistry. It can be used as an important raw material for synthesizing other substances, just like the cornerstone of building a magnificent building. After ingenious combination, it can give birth to all kinds of wonderful new substances. Its reactivity is specific, and under specific conditions, it can trigger unique chemical changes, like mysterious magic, creating a different chemical landscape.
    Exploring this substance requires fine operation and rigorous attitude. A slight mistake may lead to a thousand miles of confusion. Therefore, we chemical researchers should treat them with awe and caution, and strive to unearth more scientific treasures in their research, contributing to the development of chemistry.
    Physical & Chemical Properties
    4-Iodo-1H-Indazole, the rationalization of its material is related to our research. This substance, in its shape, may be solid, and its color may be white to light yellow. Its melting point is fixed, considering its purity. As for solubility, it may have a certain solubility in organic solvents, such as ethanol and acetone, while it is slightly soluble in water. Its stability is also considered, and it can be relatively stable at room temperature and dry conditions. In case of strong light, hot topics or specific chemical agents, it may change. Its spectral characteristics are characterized in infrared, nuclear magnetic and other spectra, which can help us to clarify its structure. The physicochemical properties of 4-Iodo-1H-Indazole are also crucial for their preparation and application, which cannot be ignored.
    Technical Specifications & Labeling
    Today there is 4 - Iodo - 1H - Indazole. The investigation of process specifications and identification (product parameters) is the top priority of our chemical researchers. Looking at the process, it is necessary to follow the precise method, the ratio of raw materials, the reaction temperature and the length of the factors are all related to the quality of the product. If the raw materials are mixed, they must be uniform and there is no difference. The reaction temperature should be controlled in a specific range, and the duration must not be inaccurate. Only then can we get high-quality products.
    As for the identification (product parameters), its purity and impurity content should be clearly marked. The judgment of purity should be tested by precise methods, and the impurity content should also be measured in detail, so that the user can understand its nature. In this way, the process specification and identification (product parameters) of 4-Iodo-1H-Indazole should be carefully studied to improve its quality and apply it widely in various fields.
    Preparation Method
    To make this 4-Iodo-1H-Indazole, take the raw materials first. Start with a certain aryl hydrazine and halogenated pyruvate, and put the two in an appropriate ratio into the reactor. Inject an appropriate amount of organic solvent, such as ethanol, into the kettle, adjust the temperature to about 60 to 80 degrees Celsius, and stir the reaction under this warm environment for several hours. This step aims to combine aryl hydrazine with halogenated pyruvate, and through the process of cyclization, initially obtain an intermediate containing a specific structure.
    Then, the intermediate is transferred to another reaction system. Add an appropriate amount of iodizing reagent, such as the combination of potassium iodide and oxidizing agent, control the temperature near room temperature, and continue to stir to make it fully reacted. In this reaction, the iodizing reagent iodizes the intermediate, resulting in the crude product of 4-Iodo-1H-Indazole.
    The crude product is refined by recrystallization. Choose a suitable solvent, such as ethyl acetate and petroleum ether miscible in a certain proportion, heat and dissolve the crude product, then slowly cool down, so that the crystals are precipitated, filtered and dried, and finally obtain a pure 4-Iodo-1H-Indazole product. The whole preparation, the ratio of raw materials, the reaction temperature and time, and the operation of each step need to be precisely controlled to obtain a good product.
    Chemical Reactions & Modifications
    4 - Iodo - 1H - Indazole is an important chemical compound. In the reaction of its chemical synthesis, it is often necessary to pay attention to the characteristics and improvement of the reaction. In the past, the reaction conditions may be harsh and the yield is not ideal.
    At present, chemists are working hard to improve the synthesis of this compound. Attempt to use a new catalyst to promote the reaction to occur under milder conditions. In this way, not only can the energy consumption be reduced, but also the purity and yield of the product are expected to be improved.
    Furthermore, the reaction path is carefully studied, the connection of each step is optimized, and the disturbance of side reactions is avoided to ensure that the reaction proceeds in the expected direction. Through these improvements, the synthesis of 4-Iodo-1H-Indazole may reach a better state and play a more critical role in many fields such as chemical industry and medicine.
    Synonyms & Product Names
    4 - Iodo - 1H - Indazole This product, the same product name is exquisite, and it is meaningful in the research. Those who are the same are different from each other in the same product, or because of the same case, or due to regional differences. Trade names often contain business considerations of merchants, aiming to promote the market.
    Test 4 - Iodo - 1H - Indazole, or have the same name, to indicate the quality of its transformation. Different texts, studies, or have their own uses. And the definition of trade names, often and easy to use, special, in order to recognize its characteristics or uses, is used in the same product.
    I am a researcher, to explore this object, it is necessary to observe the transformation of the same product name, so that we can communicate with all parties on the road of research, so as not to understand the essence of the research because of the name.
    Safety & Operational Standards
    4-Iodo-1H-Indazole safety and operation specifications
    Husband 4-Iodo-1H-Indazole is an important substance in chemical research. In the context of research, safety and operation standards are the top priority, which is related to the safety of the researcher and the success of the research.
    In terms of safety, this substance has certain characteristics and needs to be treated with caution. It may be potentially harmful to the human body, so when exposed, complete protective equipment must be worn. If wearing protective clothing, it can protect the skin from damage; wearing protective goggles can protect the eyes from accidental splashing; masks are also indispensable to prevent inhalation of particles of this substance and damage to the respiratory system.
    The operating specifications should not be underestimated. In the experimental site, ensure that the environment is well ventilated, so that the harmful gases that may escape can be quickly dissipated. When taking 4-Iodo-1H-Indazole, measure it with precise instruments, and do not cause excessive or insufficient experimental deviation. During operation, strictly observe the experimental steps and do not change the established procedures without authorization. In case of emergencies, such as material spills, do not panic, and should be dealt with according to the established emergency law. Isolate the site first to prevent others from accidentally touching it, and then clean it with appropriate materials to ensure that no hidden dangers are left.
    Furthermore, when storing, 4-Iodo-1H-Indazole should be placed in a specific environment. Avoid heat and light, and choose a dry place to prevent its properties from changing. And the label is clear, indicating the name, characteristics and precautions, so that the user can see at a glance.
    In short, the research and application of 4-Iodo-1H-Indazole is based on safety and operating standards. Only by following these two can the research road be smooth, and researchers can move forward steadily on the road of chemical exploration.
    Application Area
    4-Iodo-1H-Indazole is also a new product of transformation. The field of its use is quite wide. In the genus of medicine, it may be the key to healing diseases. Special agents can be made to treat various diseases, such as diseases and paralysis, hoping to achieve miraculous effects and relieve the suffering of patients.
    In the way of researching new materials, it is also possible. Can combine with other things to produce strange materials, with extraordinary properties, such as strong and tough, or have wonderful conductivity, which can be used in equipment and utensils to make their performance better.
    Furthermore, in the progress of chemical research, this product is also the cornerstone. The research assistant explores the secrets of chemistry, the law of responding to things, opens up new paths, produces new technologies, provides precious resources, promotes the prosperity of the chemical industry, benefits the country and the people, and has made great contributions.
    Research & Development
    In recent years, we have developed a pharmaceutical industry, with the name 4-Iodo-1H-Indazole, and we have devoted ourselves to our research. Its unique nature, exquisite structure, and wonderful principles.
    At the beginning, we explored the method of its synthesis, but it was difficult many times, and all paths were difficult or impure. However, we were not discouraged, and we repeated our research, and finally obtained an exquisite method, which can make purer products.
    Then study its performance, and in the field of medicine, observe its effect on diseases, hoping to add a sharp tool for the treatment of diseases. And look at its stability and compatibility, paving the foundation for future applications.
    Looking to the future, hoping to use this as a basis to expand new paths. Or it can be combined with other things to make stronger medicines; or it can be used in other fields for unique purposes. We are determined to expect this thing to bloom and benefit the world in the process of research and development.
    Toxicity Research
    The toxicity of 4 - Iodo - 1H - Indazole has been studied with great effort recently. This substance is new, its nature is unknown, and the doubtful sinuses are yet to be solved.
    Its shape was initially observed, and it was colorless and crystalline, which seemed harmless, but it could not be profiled. The white mice were tested and fed food containing this substance. After a while, the white mice gradually became slack, their diet decreased sharply, and their hair was dull. From the dissection, the organs changed slightly, the liver color was slightly different, and the kidneys were also shaped.
    It was also tested in plants, and the liquid containing this substance was sown on the seedlings. The seedlings grew slowly, and the leaves were macular, which seemed to be damaged. Although the experimental samples were limited, the signs of toxicity have been revealed. In the future, we should collect a wide range of data, deeply study its rationale, clarify its poison source and poison path, in order to avoid its harm and ensure the safety of all living beings.
    Future Prospects
    Viewer 4-Iodo-1H-Indazole This object is unique in its nature and has hidden opportunities in various fields. Although the power of the present has not been revealed, the prospect of the future is like the beginning of the stars, full of hope.
    We observe it with the eyes of science, observe its structure, study its characteristics, and hope to find many wonders. Or in the way of medicine, add new power to eliminate diseases and diseases; or in the field of materials, create different materials and increase their effectiveness.
    Although the road ahead is long and the geometry is unknown, we scientific researchers should move forward with determination and fearlessness. With time and careful study, 4-Iodo-1H-Indazole will be able to bloom, paint a magnificent chapter in the future, and contribute to the well-being of mankind. This is our eagerness for its future development.
    Where to Buy 4-Iodo-1H-Indazole in China?
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    Frequently Asked Questions

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    What is the main use of 4-iodo-1h-indazole?
    4-Iodo-1H-indazole is one of the organic compounds. Its main uses are quite extensive, and it has a significant effect in the field of medicinal chemistry. Because of its unique chemical structure, it can interact with specific targets in organisms, so it is important for drug developers and is often used as a lead compound to explore new drugs. In this process, scientists can modify its structure, adjust its activity and selectivity, and hope to develop innovative drugs with good efficacy and small side effects.
    In the field of materials science, 4-iodo-1H-indazole also has applications. Due to its some properties, it may participate in the construction of special functional materials. For example, in the development of organic optoelectronic materials, it may affect the optical and electrical properties of the materials, providing the possibility for the development of new optoelectronic materials. It can be introduced into the material structure through specific synthesis methods to obtain the required special properties, such as enhancing the luminous efficiency of the material or improving its electrical conductivity.
    Furthermore, in the field of organic synthetic chemistry, 4-iodo-1H-indazole is often used as a key intermediate. Chemists can take advantage of the activity of their iodine atoms to carry out various chemical reactions, such as coupling reactions. Through these reactions, more complex organic molecular structures can be constructed, expanding the path of organic synthesis, and assisting in the synthesis of organic compounds with specific functions and structures, promoting the development of organic synthetic chemistry.
    What are the physical properties of 4-iodo-1h-indazole?
    4-Iodo-1H-indazole is an organic compound, and its physical properties are of great interest. They are described as follows:
    1. ** Appearance and Properties **: This compound is usually in the state of white-like to light yellow crystalline powder. This appearance property can be used as a preliminary basis for identification in chemical experiments and industrial production. The shape of the powder is also conducive to its dispersion and dissolution in various solvents, and then participates in subsequent chemical reactions.
    2. ** Melting Point **: 4-iodo-1H-indazole has a specific melting point, which is between 160-165 ° C. As an important physical constant of the substance, the melting point is of great significance for the identification of its purity. If the measured melting point is consistent with the standard value and the melting range is narrow, it can be preliminarily determined that the purity of the substance is quite high; on the contrary, if the melting point deviates from the standard value, or the melting range is wide, it indicates that the substance may contain impurities.
    3. ** Solubility **: The solubility of organic solvents is another key physical property. It exhibits good solubility in common organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), and dimethyl sulfoxide (DMSO). This property makes it useful in the field of organic synthesis. Chemists can use these organic solvents to dissolve it and mix it well with other reactants to promote the smooth progress of the reaction. However, its solubility in water is poor, which also limits its application in some aqueous systems.
    4. ** Density **: The density of this compound is about 2.05 g/cm ³. Density data is crucial when it comes to converting the mass and volume of the substance and judging its distribution in the mixed system. In the process of preparing or processing 4-iodo-1H-indazole, knowing its density can help to accurately measure and operate.
    5. ** Stability **: Under normal conditions, 4-iodo-1H-indazole has a certain stability. However, it should be noted that it is more sensitive to light and heat. Light or high temperature environment may cause molecular structure changes, causing decomposition or other chemical reactions. Therefore, when storing this compound, it should be stored in a cool, dark place and properly sealed to ensure the stability of its quality and performance.
    What are the chemical properties of 4-iodo-1h-indazole?
    4-Iodo-1H-indazole is an organic compound with unique chemical properties. Its molecules contain iodine atoms and 1H-indazole structures, which endow the compound with specific reactivity and physical properties.
    This compound has high nucleophilic substitution reactivity due to the presence of iodine atoms. Iodine atoms can easily leave, allowing other nucleophiles to react with it to form new carbon-heteroatom bonds. It is often used as an intermediate in organic synthesis to construct more complex organic molecular structures.
    The 1H-indazole part of 4-iodo-1H-indazole contains nitrogen heterocycles, which are basic and can react with acids to form salts. And the heterocyclic electron cloud has a special distribution, which makes the whole molecule have a certain aromaticity, which affects its stability and reactivity.
    From the perspective of physical properties, 4-iodo-1H-indazole has a certain solubility in organic solvents, and the specific solubility varies according to the type of solvent and temperature. Its physical constants such as melting point and boiling point are also determined by intermolecular forces, which are of great significance for the separation, purification and identification of compounds.
    In chemical reactions, 4-iodo-1H-indazole can participate in a variety of reactions. In addition to nucleophilic substitution reactions, cyclization reactions and coupling reactions may also occur. Under suitable conditions and catalysts, intramolecular or intermolecular reactions can form new cyclic structures or connect with other organic fragments, expanding their applications in medicinal chemistry, materials science and other fields.
    In summary, 4-iodo-1H-indazole exhibits diverse chemical properties due to its unique chemical structure, providing a broad space for organic synthesis and related fields of research.
    What are the synthesis methods of 4-iodo-1h-indazole?
    4-Iodo-1H-indazole is an important organic compound, and there are many synthesis methods, which are described in detail today.
    First, with o-nitrotoluene as the starting material, halogen atoms are introduced into the benzene ring at a specific position through halogenation reaction, and then the nitro group is converted into an amino group through reduction step, and then the indazole ring is constructed through cyclization reaction. Finally, iodization reaction is carried out under suitable conditions, and iodine atoms are introduced at the target position to obtain 4-iodo-1H-indazole. The raw materials for this route are easy to obtain, but the steps are slightly complicated, and the reaction conditions of each step need to be precisely controlled to ensure higher yield and purity.
    Second, taking indole as the starting material, the indole is first protected to prevent unnecessary reactions, and then iodine atoms are introduced through specific electrophilic substitution reactions, and then 4-iodo-1H-indazole is prepared through a series of reactions such as deprotection and cyclization. The key to this method is the selection of protective groups and the timing of removal, and the electrophilic substitution reaction needs to select suitable reagents and conditions to achieve the purpose of precise positioning of iodine atoms.
    Third, the synthesis of transition metal catalytic coupling reaction is used. For example, using halogenated indolazole and iodine as raw materials, under the action of transition metal catalysts (such as palladium, copper, etc.), carbon-iodine bond coupling is realized to generate 4-iodo-1H-indazole. This method has the advantages of high efficiency and good selectivity, but transition metal catalysts are expensive, the reaction cost is high, and the reaction equipment and operation requirements are strict to ensure the smooth progress of catalyst activity and reaction.
    The above synthesis methods have their own advantages and disadvantages. In practical application, the optimal path should be selected to prepare 4-iodo-1H-indazole according to factors such as raw material availability, cost considerations, and product purity requirements.
    Where is 4-iodo-1h-indazole used?
    4-Iodo-1H-indazole is also an organic compound. It is very useful in the field of pharmaceutical research and development. It has a unique structure and potential biological activity, and can be used as a lead compound to help create new drugs. In the exploration of anti-cancer drugs, researchers hope that it can interact with specific targets of cancer cells, block cancer cell proliferation signaling pathways, or induce cancer cell apoptosis, and find new ways to overcome cancer problems.
    In the field of neurological disease drug research, it also has potential. It can regulate neurotransmitter transmission, or affect nerve cell physiological function, and is expected to relieve symptoms of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease.
    In the field of materials science, 4-iodo-1H-indazole can also be used. Due to its special chemical structure, it may be used to prepare materials with unique optoelectronic properties. It can be applied to organic Light Emitting Diodes (OLEDs) to improve the luminous efficiency and stability of devices, contributing to the development of display technology; or it can be used to prepare sensor materials, with its selective identification ability of specific substances, to achieve sensitive detection of harmful substances or biomarkers in the environment.
    In addition, in the field of agricultural chemistry, it may be developed into new pesticides. Utilizing its biological activity, it can inhibit or kill crop pests and pathogens, and compared with traditional pesticides, it may have advantages such as low toxicity and environmental protection, contributing to the sustainable development of agriculture.