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What is the chemical structure of 4-iodo-1h-pyrazolo [3,4-b] pyridine?
4-Iodo-1H-pyrazolo [3,4-b] pyridine is an organic compound. It has a unique chemical structure and is composed of a pyrazolo-pyridine parent nucleus. In this structure, the pyrazolo ring fuses with the pyridine ring in a specific form to form a double ring system.
The key to this compound is that the first position of the pyrazolo ring is a hydrogen atom (1H represents a hydrogen atom at the first position), and the fourth position of the pyridine ring is connected with an iodine atom. The structure of pyrazolo-pyridine gives the compound unique physical and chemical properties, and has attracted much attention in the fields of organic synthesis and medicinal chemistry. Due to its unique electron distribution and spatial structure, it can be used as an important intermediate for the synthesis of complex molecules with biological activity. In drug development, it may participate in the construction of compounds with specific pharmacological activities, laying the foundation for the creation of new drugs. In short, the chemical structure of 4-iodo-1H-pyrazolo [3,4-b] pyridine determines its potential application value in many fields.
What are the main uses of 4-iodo-1h-pyrazolo [3,4-b] pyridine?
4-Iodo-1H-pyrazolo [3,4-b] pyridine is an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of medicinal chemistry to create new drugs. Due to its unique chemical structure, it can interact with specific biological targets, so it has attracted much attention when developing antibacterial, antiviral and anti-tumor drugs.
In the field of materials science, it may be used to prepare materials with special photoelectric properties. Due to its molecular structure, it can produce specific responses to light and electricity, or can be applied to the research and development of Light Organic Emitting Diode (OLED), solar cells and other materials, providing the possibility for the development of high-performance optoelectronic devices.
In the field of organic synthesis, it is an important synthetic building block. With the reactivity of its iodine atom and pyrazolopyridine structure, it can build more complex organic molecular structures through various organic reactions, expand the types and functions of organic compounds, and contribute to the development of organic synthetic chemistry.
What are the synthesis methods of 4-iodo-1h-pyrazolo [3,4-b] pyridine?
4-Iodo-1H-pyrazolo [3,4-b] pyridine is an important organic compound, and its synthesis method is quite critical. The common synthesis route is to use nitrogen-containing heterocyclic compounds as starting materials.
One method is to start with an appropriate pyridine derivative to interact with a specific halogenating agent to introduce iodine atoms. This step requires attention to the precise control of the reaction conditions, such as temperature, solvent and reactant ratio, because these factors have a great influence on the selectivity and yield of the iodine substitution reaction. Then, the structure of pyrazolopyridine is constructed by cyclization. In this cyclization process, suitable catalysts and bases are often selected. Different catalysts and bases have different effects on the reaction rate and product purity.
Another method can start from pyrazole compounds, modify the pyrazole ring first, and then connect it with the pyridine-related fragments. In this connection reaction, the reaction conditions need to be carefully designed to ensure the smooth progress of the reaction and obtain the target product. In the synthesis process, separation and purification steps are indispensable, and means such as column chromatography and recrystallization are commonly used to obtain high-purity 4-iodo-1H-pyrazolo [3,4-b] pyridine. Every step of the synthesis requires careful consideration of various reaction parameters and careful operation to produce this compound efficiently and with high purity, which lays a good foundation for subsequent research and application.
What are the physical properties of 4-iodo-1h-pyrazolo [3,4-b] pyridine?
4-Iodo-1H-pyrazolo [3,4-b] pyridine is an organic compound with unique physical properties. It is mostly solid at room temperature, and its appearance may be a crystalline powder, due to the arrangement and interaction of atoms in the molecular structure. The melting point of this compound varies depending on the experimental conditions of precise determination, but it is roughly within a certain range. Intermolecular forces and crystal structures have a significant impact on the melting point. Strong intermolecular forces such as hydrogen bonds and van der Waals forces increase the melting point.
The solubility of 4-iodo-1H-pyrazolo [3,4-b] pyridine is also concerned. Its solubility in organic solvents may vary. Common organic solvents such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc. Due to the principle of "similar miscibility", this compound can be dissolved when the force between the molecules of the organic solvent is appropriate. The solubility in water may be poor, because the molecular polarity does not match the polarity of the water molecule well, and the lack of strong interaction groups with water forms.
The density of this compound is related to the molecular weight and the degree of molecular accumulation. Its density can be determined under specific experimental conditions, providing a reference for practical applications such as the ratio of materials in the reaction system.
In addition, the stability of 4-iodo-1H-pyrazolo [3,4-b] pyridine under external conditions such as light and heat needs to be considered. Light or intramolecular electron transitions, chemical bond breaks, etc. If a certain temperature is reached under the action of heat, or reactions such as decomposition and rearrangement are initiated, the stability of iodine atoms and pyrazolpyridine skeletons in the molecular structure will affect each other under different conditions to determine the overall stability of the compound.
What is the price range of 4-iodo-1h-pyrazolo [3,4-b] pyridine in the market?
I don't know the price range of 4 - iodo - 1h - pyrazolo% 5B3% 2C4 - b% 5Dpyridine in the market. This compound may be a special chemical reagent, and its price often varies depending on quality, purity, supplier, purchase volume, and market supply and demand. To know the exact price range, follow the following ways:
First, ask the chemical reagent supplier. Many professional chemical reagent companies sell such chemicals. You can log in to their official website to find this product, or call the merchant directly to ask the price. Different suppliers have different prices due to different cost and profit considerations.
Second, visit chemistry-related forums and communities. Many chemical practitioners, researchers gather here, or people who use this compound can share purchasing experience and price information. However, such information may not be accurate due to changes in time and regions.
Third, refer to academic literature and research reports. Some literature may mention the purchase of this chemical, or attach relevant price clues, but it is difficult to reflect the current real-time price.
Due to the lack of sufficient information, it is difficult to determine the price range of 4-iodo-1h-pyrazolo% 5B3% 2C4-b% 5Dpyridine. If you want to know, you should follow the above channels to explore.