4 Iodo 3 5 Dimethyl 1h Pyrazole

4-Iodo-3,5-dimethyl-1H-pyrazole (4-iodo-3,5-dimethyl-1H-pyrazole) This substance has a wide range of uses. In the field of medicinal chemistry, it is an important intermediate in organic synthesis. Geinpyrazole compounds have a variety of biological activities, such as anti-inflammatory, antibacterial, antiviral, anti-tumor, etc. 4-iodo-3,5-dimethyl-1H-pyrazole can participate in many chemical reactions due to its iodine atom and methyl properties, helping pharmaceutical developers create novel active molecules to treat various diseases.
In the field of materials science, it also has potential. After a specific reaction, it can be introduced into polymer materials to give the material special properties, such as improved material stability, optical properties, etc. Because of its structure containing nitrogen heterocycles and iodine atoms, it can interact with other substances in a specific way, thereby optimizing the microstructure of the material and improving the quality of the material.
Furthermore, in the field of pesticide chemistry, pyrazole derivatives are often used as active ingredients. 4-Iodine-3,5-dimethyl-1H-pyrazole can be modified and transformed, or pesticides with high insecticidal and bactericidal activities can be prepared, protecting crops from pests and diseases and ensuring agricultural harvests. In conclusion, 4-iodine-3,5-dimethyl-1H-pyrazole has a key use in many fields due to its unique structure, and is an important raw material for scientific research and industrial production.

4-Iodine-3,5-dimethyl-1H-pyrazole is one of the organic compounds. Its physical properties are quite impressive.
When it comes to appearance, it is usually in a solid state, but its specific form is either crystalline or powder-shaped, depending on the preparation method and the conditions of the environment.
As for the melting point, the melting point of this substance is in a specific temperature range. Sadly, the exact value is not available, because the relevant data often vary slightly due to differences in research. Basically, the determination of the melting point depends on the strength of the intermolecular force. In this compound, iodine atoms, methyl groups and pyrazole rings interact to form a unique molecular structure, which has a significant impact on the melting point. The presence of methyl groups increases the steric resistance of the molecule, while the heavier mass and larger volume of iodine atoms also change the van der Waals force between molecules, which in turn affects the melting point.
In terms of solubility, it exhibits a certain solubility in organic solvents, such as common ethanol and dichloromethane. This is because the molecular structure of the compound has both polar and non-polar parts. The pyrazole ring has a certain polarity, and the iodine atom also contributes part of the polarity, while the methyl group is non-polar. Therefore, according to the principle of similar compatibility, it is soluble in some organic solvents. However, in water, its overall hydrophobicity is slightly stronger, so its solubility is not good.
Density is also one of its physical properties. Although the exact density value is unknown, it is conceivable that its density should be similar to that of organic compounds with similar structures. The size of the density is closely related to the mass and packing method of the molecule. The molecular structure of this compound determines the compactness of its molecular packing, which affects the density.
To sum up, the physical properties of 4-iodine-3,5-dimethyl-1H-pyrazole are determined by its unique molecular structure. In the field of organic synthesis and related research, the clarity of its physical properties is crucial.

The chemical synthesis method of 4-iodine-3,5-dimethyl-1H-pyrazole is detailed as follows.
To prepare this product, 3,5-dimethyl-1H-pyrazole is often used as the starting material. First take an appropriate amount of 3,5-dimethyl-1H-pyrazole and place it in a suitable reaction vessel. This container must be clean and dry to prevent impurities from disturbing it.
Then slowly add an iodizing agent to the reaction system. Commonly used iodizing reagents, such as N-iodosuccinimide (NIS), can make the iodization reaction proceed smoothly due to their good reactivity and selectivity. When adding NIS, care should be taken to control the addition speed to avoid too violent reaction. The temperature of the
reaction is also a key factor. Generally speaking, the reaction temperature can be controlled in a moderate range, such as room temperature to 50 ° C. If the temperature is too low, the reaction rate is slow and takes a long time; if the temperature is too high, it may cause side reactions and reduce the purity of the product.
Under these conditions, at a specific location of 3,5-dimethyl-1H-pyrazole, due to the electron cloud distribution characteristics of the pyrazole ring, iodine atoms will selectively replace one of the hydrogen atoms, resulting in 4-iodine-3,5-dimethyl-1H-pyrazole.
After the reaction is completed, the product may contain impurities such as unreacted raw materials and by-products. At this time, it can be separated and purified by column chromatography. Using silica gel as the stationary phase, a suitable eluent, such as a mixed solvent of petroleum ether and ethyl acetate, was selected to achieve effective separation of each component according to the difference in the partition coefficient between the stationary phase and the mobile phase, and finally obtained a pure 4-iodine-3,5-dimethyl-1H-pyrazole.

Today there are 4-iodo-3,5-dimethyl-1h-pyrazole, and the price in the market is difficult to determine. The price of this compound often varies due to many reasons. First, the difficulty of preparation is also easy. If the preparation method is difficult, the materials used are rare, and the process is complicated, the price will be high; if the preparation method is simple, and the materials used are widely available, the price will be low. Second, the state of supply and demand is also. If there are many people in the market who want it, but there are few people who supply it, the price will be higher; if there are few people who want it, and there are many suppliers, the price will be lower. Third, the difference in quality is also. Those with excellent quality will be more expensive than those with poor quality. In addition, the price of this compound varies depending on the place where it is located. In prosperous places, commercial taxes, freight, etc. may be high, and the price will follow; in remote places, or due to logistics inconvenience, the price may vary. And the market conditions are changing rapidly, and it is difficult to predict the rise and fall of the price. To know the exact price, you must ask the merchants of chemical materials, or investigate it carefully in the market. However, only according to the current situation, without involving all kinds of on-the-spot investigations, it is difficult to determine the exact price.

4-Iodine-3,5-dimethyl-1H-pyrazole is also an organic compound. Its storage conditions are crucial and related to the stability and quality of this substance.
This substance should be stored in a cool, dry and well-ventilated place. Cover a cool environment to reduce its chemical reactions caused by excessive temperature and avoid its decomposition or deterioration. A dry place can prevent moisture from invading, because many organic compounds are prone to reactions such as hydrolysis in contact with water, which damages their structure and properties. Good ventilation can disperse volatile gases that may accumulate in time to avoid potential safety hazards.
Furthermore, it should be stored separately from oxidants, acids, bases and other substances. This is because these substances are chemically active and coexist with 4-iodine-3,5-dimethyl-1H-pyrazole, which is easy to induce chemical reactions, or cause serious consequences such as combustion and explosion.
Storage containers should also be carefully selected, and containers with excellent sealing performance should be used to prevent volatilization and leakage. And the material of the container should not chemically react with the compound. Glass or specific plastic materials are often suitable.
In addition, obvious warning signs should be set in the storage area to inform others of the danger of this substance. And regularly check the storage status to see if the container is damaged, leaking, and whether the environmental temperature and humidity are in compliance, etc., to ensure its safe storage. Therefore, 4-iodine-3,5-dimethyl-1H-pyrazole must be properly stored to stabilize its properties for subsequent use.