4 Iodo 3 Aminopyridine

The amino group is an important group in organic compounds. It is composed of nitrogen atoms and hydrogen atoms, and has unique chemical properties. It plays a key role in many chemical reactions and biological processes.
Amine is basic, which is one of its remarkable chemical properties. Because nitrogen atoms have lone pairs of electrons and can accept protons, they can exhibit alkalinity in aqueous solutions. For example, ammonia ($NH_3 $) can be regarded as the simplest amine. Ammonia can react with water in water to form ammonium ions ($NH_4 ^ + $) and hydroxide ions ($OH ^ - $), making the solution alkaline. Organic amines also have similar properties, and aliphatic amines are usually more alkaline than aromatic amines. This basic difference is due to the structural differences of different amine groups. The electron supply effect of alkyl groups in fatty amines enhances the electron cloud density of nitrogen atoms, making it easier to accept protons. In aromatic amines, the solitary pair electrons of nitrogen atoms are conjugated with the π electrons of benzene rings, reducing the electron cloud density of nitrogen atoms, causing their ability to accept protons to weaken, and their alkalinity is also reduced.
Amine groups can also participate in nucleophilic substitution reactions. Due to the solitary pair electrons of nitrogen atoms, they are nucleophilic and can attack electrophilic reagents. For example, when halogenated hydrocarbons react with amines, the nitrogen atoms of amines can attack the carbon atoms of halogenated hydrocarbons, and the halogen atoms leave to form new nitrogen-containing compounds. This reaction is widely used in organic synthesis and can be used to prepare a variety of amine derivatives.
In addition, the amine group can undergo acylation reaction. The amine interacts with acylating reagents such as acyl halide and acid anhydride, and the hydrogen atom on the nitrogen atom is replaced by an acyl group to form an amide. Amids are important structural units in living organisms, and the peptide bond of proteins is the amide bond. This reaction is of great significance in the fields of organic synthesis and biochemistry. It can not only be used to prepare organic compounds with specific functions, but also helps to understand the synthesis and metabolism of proteins in living organisms.
In addition, amine groups can still participate in the diazotization reaction. Aromatic primary amines react with nitrous acid in low temperature and strong acid medium to form diazonites. Diazo salts are chemically active and can undergo many reactions, such as coupling reactions, to form azo compounds. Azo compounds often have bright colors and are widely used in the dye industry.
In summary, the chemical properties of amine groups are diverse and play an important role in many fields such as organic synthesis, biochemistry, and dye industry. The in-depth exploration and clever application of their properties have promoted the development of chemistry and related industries.

Amino groups are usually synthesized in many ways. One method can be obtained from the original method of nitro compounds. For example, gold acid is used to make the nitro compound react, and the nitro group then converts to the amine group. In the past, there was a saying: "By combining nitrobenzene with dilute acid, aniline is obtained." This is by the action of gold acid, the nitro group is originally formed into an amine group.
Another method is the inverse of ammonia. The atom activity of ammonia is high, and the nitrogen atom in ammonia is rich in seeds. When the two meet, the atom is replaced by ammonia, and the first amine is obtained. However, it is not easy to stop with one amine, and it is often reversed to obtain diamine, triamine and even seasonal amines. In ancient times, there was a way to measure ammonia with bromoethane, which was co-placed in a dense device, and to promote its reaction, ethylamine can be obtained, but there are also side effects.
The source of nitrile is also a method of synthesizing amine groups. Nitrile groups can be synthesized by the original amine group under suitable conditions. Catalysis of gold is used to catalyze gold, such as gold and gold, so that the nitrile group can be added and reversed, and the nitrile group can be reduced by amines. The ancients used benzyl cyanide to obtain phenethylamine, which is an example of the original amine of nitrile.
The Hoffman degradation reaction of amines can also be used in the synthesis of amine groups. Under the action of acetamide, amide is rearranged, and the amide group is reduced by one less carbon atom. As in the past, methylamine can be obtained by co-reaction of acetamide bromine and oxidation. This process is ingenious and can be synthesized by amine groups.

I look at your question and ask about the application field of amino groups. Amino groups are useful in many fields, and listen to me one by one.
In the field of medicine, the role of amino groups is crucial. Many drug molecules contain amino structures, which can interact with targets in organisms. For example, antibiotics, some amino groups bind to specific proteins in bacteria to hinder the growth and reproduction of bacteria, in order to achieve antibacterial effect. Another example is anti-histamine drugs, which bind amino groups to histamine receptors to relieve allergic symptoms and relieve pain for many allergic patients.
Amino groups are also common in the chemical industry. In the synthesis of polymer materials, amino-containing compounds are important raw materials. Such as polyamide materials, nylon is a typical example, which is formed by condensation of amino-containing monomers and carboxyl-containing monomers. This material has high strength, wear resistance and other characteristics, and is widely used in textiles, engineering plastics, etc., such as making clothing, mechanical parts, etc.
In the agricultural field, amino groups are also useful. Some amino-containing fertilizers can provide nitrogen nutrition for plants and promote plant growth. And amino groups can improve soil structure, improve soil fertilizer and water retention capacity, which is conducive to the growth of crops, and improve yield and quality.
In the field of biochemistry, proteins and nucleic acids are important material bases for life, while proteins are composed of amino acids, and amino acids contain amino groups. Amino groups participate in the construction of protein structure and function, and determine protein characteristics and activity. In nucleic acids, bases also contain amino-related structures, which are of great significance for the transmission and expression of genetic information.
In addition, the properties of amino groups are often used in the paint and dye industries. Amino-containing resins are used in coatings to improve the hardness, adhesion and chemical resistance of coatings. The introduction of amino groups into dye molecules can change the color and dyeing properties of dyes, making dyeing more uniform and firm.
In summary, amino groups have a wide range of key applications in many fields such as medicine, chemical industry, agriculture, biochemistry, and paint dyes, and have a profound impact on human life and social development.

Looking at today's world, the trade is complicated, which is related to the price of aminophenyl in its market, and also involves various variables.
Aminophenyl is widely used in various fields of chemical industry, and its price often changes with the state of supply and demand. If the market demand is prosperous, but the supply is small, the price will rise. If the industry is booming, the demand for aminophenyl increases sharply, but the producers fail to respond quickly, resulting in thin goods and high prices. This is still a dry grain, and the price cannot be suppressed.
The price of raw materials is also the key. The production of aminophenyl requires all kinds of raw materials. If the price of raw materials is high, the cost of the production will increase, and its market price will also rise. If the materials used to build a building are expensive, the price of the building will also be high.
Furthermore, the regulations of the government and the progress of technology can affect its price. If the government is strictly regulated, it will cause changes in production, or it will be difficult to increase its production, and the price will also be affected by it. And if the technology is new, the efficiency of the product will increase, the cost may decrease, and the price may decrease. For example, replacing old equipment with new equipment, the efficiency will increase and the cost will decrease.
The dispute between the same industry is also the main reason. In the city, there are many aminophenyl-based people competing for profit, or lowering their prices to attract customers, so the price may drop. Just like a group of merchants gathered in the market, each of them wants to sell their goods, and they must win with the best price.
From the perspective of aminophenyl, the market price is not determined uniformly, and supply and demand, raw materials, political regulations, technological progress, and industrial competition are all intertwined. Businesspeople who want to understand the change of its price must look at all the conditions and analyze the details before they can make profits in response to the market.

In the method of alchemy in "Tiangong Kaiwu", the storage of mercury is related to many subtleties. Mercury is naturally mobile and easy to evaporate and escape, so its storage conditions are quite strict.
If you want to properly store mercury, choose the first heavy container. You need to use a special pottery urn or metal container. These containers must be tight and seamless to prevent the leakage of mercury. Because of its solid texture, it can resist the erosion of mercury and ensure the safety of mercury.
Second, the environment is crucial. The storage place should be cool, dry and moderately ventilated. Cool, which can slow down the evaporation rate of mercury; dry, to avoid its contact with water vapor and cause other changes; moderately ventilated, but not too smooth, to prevent mercury gas from escaping too much. If it is in a humid place, mercury is easy to vaporize and combine with water, causing its qualitative change; if the environment is extremely hot, the evaporation of mercury is like flying and fleeting.
Furthermore, the sealing technique cannot be ignored. On the container, it must be tightly sealed, or sealed with special wax, or covered with a heavy cover, so that the mercury is isolated from the outside air. When the edge mercury encounters the air, it is easy to oxidize and change, which damages its quality. Therefore, sealing is the key to protecting mercury.
The storage of mercury requires all conditions such as container, environment, and seal to be prepared before it can be preserved. The experience accumulated by the practice of alchemy by the ancient sages is cherished by future generations, so as to preserve the characteristics and functions of mercury, which is of great significance in alchemy and all kinds of mercury use.