Competitive 4-Iodo-6-Methoxypyrimidine prices that fit your budget—flexible terms and customized quotes for every order.
For samples, pricing, or more information, please call us at +8615371019725 or mail to
sales7@bouling-chem.com.
We will respond to you as soon as possible.
Tel: +8615371019725
Email: sales7@bouling-chem.com
As a leading 4-Iodo-6-Methoxypyrimidine supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemistry of 4-iodo-6-methoxypyrimidine?
4-Iodine-6-methoxypyrimidine, this is an organic compound with interesting chemical properties.
Let's talk about the influence of its substituents first. Methoxy (-OCH) is an electron donor group, which can produce electronic effects on the pyrimidine ring. Due to the characteristics of the electron donor of the methoxy group, the electron cloud density on the pyrimidine ring increases, especially in the adjacent and counterposition of the carbon atom connected to the methoxy group. This property has a great impact on its reactivity.
The iodine atom (-I) is also an important part of this compound. The iodine atom is relatively large and has a certain electronegativity. On the one hand, its large volume will produce a steric hindrance effect; on the other hand, its electronegativity makes it absorb electrons to a certain extent and interact with the electron-giving interaction of the methoxy group.
In terms of reactivity, in the nucleophilic substitution reaction, the attractiveness of the nucleophilic reagent changes because the methoxy group increases the electron cloud density of the pyrimidine ring. The iodine atom acts as a leaving group, and nucleophilic substitution reactions can occur. For example, when a suitable nucleophilic reagent exists, the nucleophilic reagent can attack the carbon atom connected to the iodine on the pyrimidine ring, and the iodine ion leaves, thereby generating new compounds.
In terms of redox reaction, the pyrimidine ring of this compound is relatively stable, but some strong oxidizing agents or reducing agents may still react with it. In case of strong oxidizing agents, the substituents on the ring may undergo oxidative changes; while strong reducing agents may affect the electronic structure of the pyrimidine ring.
Furthermore, the solubility of this compound is also worth mentioning. Because it contains methoxy groups, it may have some solubility in organic solvents. However, the existence of iodine atoms and pyrimidine rings makes its solubility different from that of ordinary methoxy-containing compounds. Overall, its chemical properties are determined by the interaction of pyrimidine rings, methoxy groups and iodine atoms, and may have unique uses in organic synthesis and other fields.
What are the main uses of 4-iodo-6-methoxypyrimidine?
4-Iodine-6-methoxypyrimidine is one of the organic compounds. It has a wide range of uses in the field of medicinal chemistry and is often a key intermediate for the creation of new drugs. Due to its special structure, many bioactive compounds can be derived by chemical modification to target specific diseases, such as the development of anti-tumor, antiviral and antibacterial drugs.
It also has its uses in the field of materials science. Or can participate in the synthesis of organic optoelectronic materials, with its unique electronic structure and chemical properties, affect the photoelectric properties of materials, such as luminous efficiency, charge transport, etc., and then apply to the preparation of organic Light Emitting Diode (OLED), solar cells and other devices.
In the field of pesticide chemistry, 4-iodine-6-methoxy pyrimidine also has important functions. It can be used as a raw material for the synthesis of new pesticides, creating pesticide products with high efficiency, low toxicity and environmental friendliness to pests, assisting agricultural pest control, and ensuring crop yield and quality.
In addition, in organic synthetic chemistry, it is often used as a building block for more complex organic molecules. Chemists can combine it with other organic fragments through various chemical reactions, such as nucleophilic substitution, coupling reactions, etc., to expand the structural complexity of molecules, so as to achieve specific chemical goals and synthesize organic compounds with novel structures and unique properties.
What is 4-iodo-6-methoxypyrimidine synthesis method?
To prepare 4-iodine-6-methoxy pyrimidine, the method is as follows. 6-methoxy pyrimidine is often used as the starting material, and it is reacted with the iodine substitution reagent first. The selected iodine substitution reagent, such as iodine elemental substance ($I_ {2} $), is combined with an appropriate oxidizing agent. Among the oxidizing agents, ammonium cerium nitrate (CAN) is quite commonly used. This combination can take advantage of the oxidizing properties of CAN to promote the iodine elemental substance to iodize 6-methoxy pyrimidine, and introduce the iodine atom at the 4-position of the pyrimidine ring to obtain 4-iodine- When
reacting, the choice of solvent is also critical. Common organic solvents, such as dichloromethane, N, N-dimethylformamide (DMF), can be considered. Dichloromethane has good solubility and moderate polarity, while DMF has stronger polarity, which can enhance the interaction between reactants. According to the actual situation of the reaction, choose the appropriate solvent to facilitate the reaction.
The reaction conditions also need to be precisely controlled. In terms of temperature, the appropriate point is usually explored between low temperature and room temperature. Reaction at low temperature can make the reaction process milder and reduce the occurrence of side reactions; if the temperature is too low, the reaction rate may be too slow. The reaction time also depends on the monitoring of the reaction process. It is often monitored by thin-layer chromatography (TLC). The reaction can only be terminated when the raw material point is basically eliminated and the product point reaches the expected level.
In addition, the pH of the reaction system also affects. According to the reagents used and the reaction mechanism, the pH value of the system can be regulated with a buffer to ensure that the reaction is advanced in a suitable acid-base environment, so that 4-iodine-6-methoxypyrimidine can be prepared efficiently and in high yield.
What is the price of 4-iodo-6-methoxypyrimidine in the market?
Looking at this question, I am inquiring about the market price of 4-iodo-6-methoxypyrimidine. However, prices in the market often change over time and are subject to various factors, such as origin, quality, supply and demand.
To know the price of this product, you can visit various cities as mentioned in "Tiangong Kaiwu". In today's world, you can find a platform for trading chemical products on the Internet and inquire about the quotation of this product. Or go to the physical chemical raw material market and ask merchants to get the actual price.
However, according to common sense, the price of fine chemical products varies greatly. If it is difficult to prepare, the raw materials are rare, or because the market demand is small, its price must be high; if it is easy to prepare, the raw materials are wide, and the demand is strong, the price may be low. It is a pity that I have not seen this thing in the market, so it is difficult to determine its price. Only by following the above method can you find out its price.
What are 4-iodo-6-methoxypyrimidine storage conditions?
4-Iodine-6-methoxypyrimidine is one of the organic compounds. The method of storage is crucial, and it is related to the stability and quality of this substance.
This substance should be stored in a cool and dry place. Cover a cool place to reduce the rate of chemical reaction caused by excessive temperature and avoid decomposition or deterioration. A dry environment is also indispensable. It may be easily affected by moisture and react with water, causing structural changes and losing its inherent nature.
Furthermore, it must be placed in a well-ventilated place. With good ventilation, harmful gases can be avoided from accumulating. If this substance evaporates harmful gases, it can be quickly dispersed to ensure the safety of the storage environment.
For storage, a sealed container should be selected. Sealing can prevent the intrusion of air, moisture and other impurities and protect its purity. It is better to use glass or specific plastic containers. These materials are chemically stable and do not react with 4-iodine-6-methoxy pyrimidine.
And must be kept away from fire sources and oxidants. This material may be flammable, and it is dangerous in case of fire; oxidants can also react violently with it, causing explosions and other dangerous situations.
In addition, the storage place should be clearly marked, indicating the name, nature and storage precautions of this object, so as to facilitate access and management, and prevent misoperation and disaster. Therefore, 4-iodine-6-methoxypyrimidine must be properly stored to maintain its stability for future use.