4 Iodo D Phenylalanine

4-Iodo-D-phenylalanine is an organic compound, belonging to amino acid derivatives and the like. Its chemical structure is unique, containing the basic structure of phenylalanine, and an iodine atom is added to the 4th position of the benzene ring, and has a D-configuration.
phenylalanine has an amino group (\ (- NH_ {2}\)) and a carboxyl group (\ (-COOH\)), which are connected to the central carbon atom. The central carbon atom is still connected to a hydrogen atom and a phenethyl group (\ (- CH_ {2} - C_ {6} H_ {5}\)). In 4-iodo-D-phenylalanine, the hydrogen atom at position 4 of the benzene ring is substituted by the iodine atom.
As for the D-configuration, it is related to the stereochemistry of the molecule. Amino acids have two configurations, L-and D-like mirror symmetry. Natural amino acids are mostly L-configuration, while 4-iodo-D-phenylalanine is D-configuration. This configuration difference may cause its biochemical properties to be different from those of L-configuration amino acids.
The chemical structure of 4-iodo-D-phenylalanine can be summarized as follows: a central carbon atom with an amino group, a carboxyl group, a hydrogen atom and a phenethyl group substituted by iodine at position 4. This unique structure makes it potentially useful in organic synthesis, medicinal chemistry and other fields. Or it can be used as a building block for the synthesis of special peptides and proteins, and the reactivity of its iodine atom can be used to introduce specific functional groups or achieve specific chemical reactions.

4-Iodine-D-phenylalanine is an important organic compound. Its main uses are roughly three.
First, in the field of medicinal chemistry, this compound is often the key raw material for the creation of new drugs. Due to its unique chemical structure, it can interact with specific targets in organisms, so it can help scientists develop specific drugs for difficult diseases such as tumors and neurological diseases. For example, its structure may be modified to precisely act on specific receptors in tumor cells, so as to achieve the purpose of inhibiting tumor growth and spread, providing new opportunities for treating serious diseases such as cancer.
Second, in biochemical research, 4-iodine-D-phenylalanine can be used as a labeling reagent. Due to its unique physical and chemical properties, scientists can gain insight into many complex biochemical reaction mechanisms in organisms by tracking their metabolic pathways and distribution in vivo. For example, when studying the synthesis and transport process of proteins, they can be introduced into the system to detect the signal of iodine and clarify the dynamic changes of proteins, providing a powerful tool for basic research in life sciences.
Third, in the field of materials science, this compound also has potential application value. By combining or modifying with other materials, new properties can be given to materials. For example, it can improve the optical and electrical properties of materials, so that they can demonstrate unique advantages in optoelectronic devices, sensors and other fields, and contribute to the innovative development of materials science. In short, 4-iodine-D-phenylalanine plays an indispensable role in many scientific fields and is of great significance in promoting progress in various fields.

4-Iodo-D-phenylalanine is an organic compound, and there are many methods for its synthesis. In the past, D-phenylalanine was often used as the starting material and obtained by iodization reaction.
One method is to dissolve D-phenylalanine with a suitable solvent, such as dichloromethane. Then, an iodizing reagent, such as N-iodosuccinimide (NIS), is added to the reaction system. This reagent can provide an iodine source under mild conditions, so that iodine atoms are introduced into the benzene ring. During the reaction, it is necessary to pay attention to the control of temperature, usually at low temperature, such as 0 ° C to room temperature, to avoid unnecessary side reactions. And it is often necessary to add a catalyst, such as Lewis acid, to promote the reaction. After the reaction is completed, the product is isolated and purified by extraction, column chromatography and other means.
There is also an electrochemical synthesis method. D-phenylalanine is placed in an electrolyte containing iodine ions, and the addition of iodine atoms to the benzene ring is realized through electrode reaction. This method is relatively green and environmentally friendly, and the reaction conditions are relatively mild. However, it requires high control of electrode materials, electrolyte composition and reaction parameters. It is necessary to finely adjust parameters such as current density and voltage to obtain the ideal yield and selectivity.
Another attempt is to synthesize it with biological enzymes. Using specific enzymes to simulate the reaction process in vivo, the iodization modification of D-phenylalanine is realized. This approach is highly selective and can precisely generate the target product. However, finding suitable enzymes and optimizing enzyme reaction conditions, such as pH value, temperature, substrate concentration, etc., requires many experiments and explorations.

4-Iodo-D-phenylalanine is a special compound with a unique mechanism of action in living organisms.
It is in living organisms, or involved in the process of protein synthesis. Protein synthesis, like the foundation of building a building of life, requires the precise participation of various amino acids. This compound may be able to intervene in the step of amino acid incorporation into proteins due to its special structure. The presence of its iodine atom may cause changes in the steric resistance, which affects the accuracy of amino acid binding to transport RNA (tRNA), and then affects the direction of protein synthesis, causing changes in the structure and function of the resulting protein.
Furthermore, it may be related to cell signaling pathways. Intracellular signaling is like a complex communication network that maintains the normal operation of cells. This compound may interact with specific receptors or signaling molecules due to its own characteristics. Such as binding to receptors on the surface of the cell membrane, triggering intracellular cascade reactions, regulating key processes such as cell growth, differentiation, and apoptosis.
Or play a role in metabolic pathways. Metabolic pathways in organisms are intertwined like a network, and each link is closely related. This compound may participate in the metabolic branch of phenylalanine, affecting the production and flow of intermediate products, changing the balance of metabolites in cells, and indirectly regulating the physiological functions of cells.
In conclusion, 4-iodo-d-phenylalanine has a complex mechanism of action in organisms, involving protein synthesis, signal transduction, metabolic regulation and many other aspects, and has a potential significant impact on the physiological and pathological processes of organisms.

4-Iodo-D-phenylalanine is a special organic compound that has attracted much attention in the fields of pharmaceutical research and biochemistry. However, its market price range is difficult to determine, due to the interaction of multiple factors.
First, the production process is complicated and simple. If the preparation method requires exquisite steps, high-end technology and special raw materials, the cost will rise and the price will also be high. For some processes that require precise chiral synthesis, the price of the products produced is high due to strict requirements on equipment and operation.
Second, the purity will determine the price. High-purity 4-iodo-D-phenylalanine is mostly used in high-end scientific research and pharmaceutical development, and the preparation is difficult, and the price can reach hundreds or even thousands of yuan per gram. And those with lower purity, or used for general research, are relatively close to the people, or tens of yuan per gram.
Third, the market supply and demand situation is critical. If the demand for pharmaceutical research and development surges during a certain period, and the supply is limited, the price will rise. On the contrary, if the supply exceeds the demand, the price will decline.
Fourth, different suppliers have different pricing strategies. Well-known large manufacturers may have high prices due to their excellent brands, quality control and after-sales services; emerging or small suppliers may have low prices for the market.
Generally speaking, laboratory purchases are small, low purity or tens of yuan per gram, high purity or hundreds of yuan. Industrial scale purchases, due to large quantities, may have discounts on unit prices, but the specifics still need to be negotiated with the supplier.