4 Iodoacetophenone
Iodobenzene

4-Iodoacetophenone

Fengxi Chemical

    Specifications

    HS Code

    217961

    Chemical Formula C8H7IO
    Molecular Weight 246.045 g/mol
    Appearance Yellow - white solid
    Boiling Point 153 - 154 °C (14 mmHg)
    Melting Point 58 - 62 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether, etc.
    Density 1.674 g/cm³
    Flash Point 151.7 °C
    Odor Characteristic odor
    Stability Stable under normal conditions but may react with strong oxidizing agents
    Chemical Formula C8H7IO
    Molar Mass 246.045 g/mol
    Appearance Yellow - brown solid
    Melting Point 58 - 62 °C
    Boiling Point 260 - 262 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Density 1.629 g/cm³
    Flash Point 110.3 °C
    Stability Stable under normal conditions, but may react with strong oxidizing agents

    As an accredited 4-Iodoacetophenone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 100g of 4 - iodoacetophenone packaged in a sealed, chemical - resistant bottle.
    Storage 4 - iodoacetophenone should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition points. Keep it in a tightly closed container to prevent moisture and air exposure. Store it separately from oxidizing agents and incompatible substances. This helps maintain its chemical stability and reduces the risk of dangerous reactions.
    Shipping 4 - iodoacetophenone is shipped in accordance with chemical regulations. Packed securely in appropriate containers to prevent leakage. Shipment often via specialized carriers with proper handling and documentation for safe transit.
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    4-Iodoacetophenone
    General Information
    Historical Development
    4-Iodoacetophenone is also an organic compound. Its initial discovery is the result of the evolution of chemical research. In the past, chemists studied organic synthesis and hoped to explore new species. At that time, all kinds of experiments were tried and successful, and in complex reaction systems, 4-Iodoacetophenone emerged.
    At the beginning, the synthesis method was cumbersome and inefficient, and only a small amount of products could be obtained. However, chemists were not discouraged. With the advance of science and technology, the analytical methods became more refined, and the insight into its structure and properties became deeper. Then the synthesis path was improved to improve the yield and purity.
    This compound is gradually valuable in the fields of materials science and drug development. Scientists continue to explore and expand its application range. Looking at its historical development, it is like a long road that chemists have explored step by step, making 4-Iodoacetophenone increasingly important from its initial appearance, and it has occupied a place in the forest of chemistry.
    Product Overview
    4-Iodoacetophenone is an organic compound. Its shape or crystalline body is white to yellowish in color. It has a special odor and is soluble in organic solvents.
    This compound is widely used in the field of organic synthesis. It can be used as an intermediate to prepare various drugs, pesticides and fine chemicals. Due to the presence of iodine atoms and acetyl groups, its chemical activity is unique and it can participate in a variety of chemical reactions, such as nucleophilic substitution and coupling reactions.
    The method of synthesis often uses acetylbenzene as the starting material and is obtained by iodization. The control of reaction conditions has a great impact on the purity and yield of the product. It is necessary to pay attention to factors such as reaction temperature, reagent ratio and reaction time to achieve the best synthesis effect.
    When storing, it should be placed in a cool, dry and well-ventilated place to avoid contact with oxidants and other substances to prevent deterioration. In this way, its quality can be guaranteed and it can be used in scientific research and industrial production to the best of its ability.
    Physical & Chemical Properties
    4-Iodoacetophenone is also an organic compound. It has unique physical and chemical properties. Looking at its physical properties, it is mostly crystalline at room temperature, white or yellowish in color, with a certain melting point, about 57 to 58 degrees Celsius. This property can help the identification and purification of substances. It has good solubility in organic solvents, such as ethanol, ether, etc., but little solubility in water.
    In terms of its chemical properties, the structure of iodine atoms and acetophenone in this compound gives it active reactivity. The electron cloud distribution of the benzene ring makes it electrophilic substitution reactions, and iodine atoms can also participate in many nucleophilic substitution reactions. Due to its unique structure and properties, it is widely used in the field of organic synthesis and is often a key intermediate for the preparation of complex organic compounds, assisting chemists in exploring the synthesis path of new substances.
    Technical Specifications & Labeling
    4-Iodoacetophenone is an important intermediate in organic synthesis. Its preparation process is very critical, and the process specifications need to be strictly followed. In the selection of reaction raw materials, high-purity starting materials should be selected to ensure product quality. Reaction conditions such as temperature, time, catalyst dosage, etc., need to be precisely controlled. If the temperature is too high or side reactions occur, the yield and purity will be affected; if the time is too short, the reaction will be incomplete.
    The identification (commodity parameters) of the product cannot be ignored. Key information such as its chemical name, molecular formula, molecular weight, and purity should be clearly marked. Purity testing should use appropriate analytical methods, such as high-performance liquid chromatography, to ensure accurate and reliable data. Warning signs should also be clearly marked on the packaging to prevent improper use. Only in this way can we ensure the orderly production and use of 4-Iodoacetophenone.
    Preparation Method
    To prepare 4-Iodoacetophenone, it is necessary to clarify the method of preparation, which is related to the raw materials and production process, reaction steps and catalytic mechanism.
    First discuss the raw materials, acetophenone and iodine are the main ones. In these two, acetophenone is the basic organic compound, and iodine is the key to introducing iodine atoms. In the production process, suitable solvents, such as glacial acetic acid, are often used to make the two blend.
    The reaction steps are as follows: acetophenone and an appropriate amount of iodine are co-placed in a reaction kettle, glacial acetic acid is added as the solvent, and the temperature is heated to a suitable temperature, about 60 to 70 degrees Celsius. During this period, the iodine and acetophenone undergo an electrophilic substitution reaction, and the
    Catalytic mechanism: In order to promote the reaction speed, an appropriate amount of catalyst can be added, such as sulfuric acid. Sulfuric acid can polarize iodine, enhance its electrophilicity, and facilitate the attack on the benzene ring, so that 4-Iodoacetophenone can be efficiently prepared.
    Chemical Reactions & Modifications
    The anti-chemical properties of 4-Iodoacetophenone are the key to chemical research. Its anti-chemical, or nuclear phase interaction, the iodine atom is easily replaced by other groups, which is often its anti-chemical properties. And its carbonyl properties can be added like anti-chemical properties, such as alcohol to generate aldehyde, all due to the activity of carbonyl groups.
    As for the modification of chemical properties, it can be improved by modifying its near-basic properties, or anti-chemical components. Increasing the degree of resistance can often promote the rate of reaction, so that the original slow reaction can be accelerated. Or adding a catalyst can also change the way of reaction, reduce the activation energy, and make the reaction easier to generate. The chemical properties of 4-Iodoacetophenone can be improved for different research and application needs.
    Synonyms & Product Names
    4 - Iodoacetophenone is also a chemical thing. Its name does not exist. Ancient books did not directly describe this thing, so it can be deduced from today's knowledge, and it can be related to it.
    This thing is named or named because of its creation or sex. Or because it contains iodo (iodo) and acetophenone (acetophenone), it is studied in ancient times, or it is similar.
    The exploration of the transformation of the past has not yet sprouted, and the name is not as relevant as it is today. However, it is deduced from its elemental composition and molecular framework, or has a similar name. For example, due to the characteristics of its iodine atom, or "iodine substituted acetylbenzene", this also means the same. The trade name, or its use and characteristics, for the purpose of promoting sales. In ancient times and today's business naming model, however, if there is a trade, or because of the chemical activity of iodine, it is used in a certain situation, and it is named "iodine live acetylbenzene" in recognition of its use.
    Safety & Operational Standards
    4 - Safety and operation of Iodoacetophenone
    4 - Iodoacetophenone is a compound commonly used in chemical research. When used, safety and operation regulations must be strictly followed to ensure the safety of the experimenter and the smooth progress of the experiment.
    #1. Safe storage
    This compound should be stored in a cool, dry and well-ventilated place. Keep away from fire and heat sources and avoid direct sunlight. Due to its certain chemical activity, contact with certain substances may cause dangerous reactions, so it should be stored separately from oxidants, reducing agents, acids, alkalis, etc., and must not be mixed. The storage area should be equipped with suitable containment materials to prevent leakage accidents.
    #2. Operating instructions
    1. ** Personal Protective Equipment **: When performing operations related to 4-Iodoacetophenone, the experimenter must wear appropriate personal protective equipment. Experimental clothing should be worn to prevent the compound from spilling on the clothing; protective gloves should be worn. It is recommended to use chemically resistant gloves, such as nitrile gloves, to avoid direct contact with the skin. At the same time, protective glasses or face masks should be worn to prevent the compound from entering the eyes.
    2. ** Ventilation facilities **: The operation should be carried out in a well-ventilated environment, and the best choice is in a fume hood. The fume hood can effectively discharge harmful gases that may be generated during the operation, reducing the risk of inhalation by the experimenter.
    3. ** Access operation **: When taking 4-Iodoacetophenone, the movement should be cautious and gentle. Use clean and dry utensils to avoid impurities from mixing in. If a specific volume or mass is required, a precise measuring tool should be selected and carried out in strict accordance with the operating procedures. After taking it, seal the container in time to prevent the compound from evaporating or reacting with air components.
    4. ** Emergency Treatment **: If 4-Iodoacetophenone leakage occurs accidentally, irrelevant personnel should be quickly evacuated to a safe area and isolated. In the case of a small amount of leakage, it can be absorbed by inert materials such as sand and vermiculite and collected in a suitable container for treatment. In the case of a large amount of leakage, a dike or pit should be built for containment, covered with foam to reduce the vapor hazard, and then contact a professional for treatment. If the experimenter accidentally comes into contact with this compound, such as skin contact, he should immediately remove the contaminated clothing, rinse with a large amount of flowing water for at least 15 minutes, and seek medical attention in a timely manner; if eye contact, he should immediately lift the eyelids, rinse thoroughly with a large amount of flowing water or normal saline, and seek medical attention promptly.
    Follow the above safety and operation norms to effectively ensure the safety of the experiment, so that 4-Iodoacetophenone can be used correctly in chemical research.
    Application Area
    4-Iodoacetophenone is also a chemical substance. Its use is involved in a wide range of fields. In the process of research and development, it can be used as an important raw material to help researchers develop new technologies, so as to cure the world's diseases. In the field of materials, it can also improve the efficacy, or the characteristics of chemical materials, making it more useful for various purposes. And in the field of chemical synthesis, 4-Iodoacetophenone is often used as a chemical substance, and it can assist chemists in the synthesis of general compounds, promoting the first step in the field of chemical science. In addition, 4-Iodoacetophenone has important value in a wide range of fields such as chemical, materials, and chemical synthesis, and is indispensable for the development of chemical research.
    Research & Development
    Today there is a thing named 4 - Iodoacetophenone. We are committed to studying its properties and methods of preparation, hoping to make progress.
    At the beginning, examine its properties, know its shape, taste, number of melting and boiling, and explore its dissolution in various solvents, to show its activity. As for the production method, search the classics and try various paths. Either replace it with acetophenone and iodide, or make it by other means. In the meantime, adjust the conditions of the reaction, such as temperature, pressure, and amount of agent, so that the yield is good and pure.
    We are committed to the exploration of this object, hoping to expand its use, either as medicine or as material, with the aim of developing its capabilities in the fields of engineering and medicine, promoting its progress, and using it for the world, in order to achieve the goal of research and development.
    Toxicity Research
    I have studied the toxicity of 4-Iodoacetophenone. This substance has also been found to have unique effects on various organisms in experiments. If you try it with insects, you will move slowly, for a little while, or if you touch it, you will be stagnant and unable to move. If you test it with plants and trees, its leaves will gradually wither and its vitality will decline.
    Cover the development of its toxicity, or because of the structure of iodine and benzophenone. The activity of iodine, or the change of biochemical synthesis, disturbs the balance of the organism; the nature of benzophenone, or breaks the order of cells. Although it is used in chemical and pharmaceutical fields, the risk of toxicity cannot be ignored. Experimenters should be careful to prevent them from being inadvertently harmed, and they must also study methods to avoid harm, so that they can be used and the harm can be minimized.
    Future Prospects
    Today there is a product named 4-Iodoacetophenone. As chemical researchers, we are full of hope for its future development. This product has unique properties and may have extraordinary uses in the field of organic synthesis.
    Looking at the progress of today's chemistry, fine synthesis is becoming increasingly important. 4-Iodoacetophenone has a lively functional group and can be used as a key intermediate to help create complex compounds. In the future, it may emerge in pharmaceutical research and development, providing new opportunities to overcome difficult diseases.
    In the field of materials science, it may be able to use its characteristics to develop new functional materials. With its structural characteristics, it is expected to prepare materials with special optical and electrical properties for high-end technology.
    We researchers should dedicate ourselves to our research and explore more potential of 4-Iodoacetophenone, contribute to the progress of science, and welcome a better future.
    Historical Development
    4-Iodoacetophenone is also an important substance in organic synthesis. Its origin, chemists in the past studied organic reactions, exploring new paths, and paying attention to this compound one by one. At the beginning, the preparation was difficult and the yield was quite low, but the scholars persevered.
    After years, the process is gradual. From the initial simple method to finding a subtle path, chemists analyze the reaction mechanism and improve the conditions. The introduction of catalysis makes the reaction efficient and the yield is also increased.
    This compound is increasingly used in pharmaceutical synthesis and is a key raw material for the preparation of special drugs; in the field of materials, it adds its unique properties. Its development history is a brilliant chapter in the history of chemistry, witnessing human wisdom and paving the way for follow-up scientific research. The future will be even brighter.
    Product Overview
    4-Iodoacetophenone is also an organic compound. Its shape is light yellow crystalline and has a special odor. It has a moderate melting point and is widely used in the field of organic synthesis.
    The preparation of this compound is often achieved through a specific chemical reaction. During the reaction process, it is necessary to precisely control the reaction conditions, such as temperature and the proportion of reactants, to ensure the purity and yield of the product.
    In terms of application, 4-Iodoacetophenone is an important intermediate in organic synthesis. With its structural properties, it can participate in a variety of reactions, and then synthesize a series of important organic compounds. It has considerable application prospects in many fields such as medicinal chemistry and materials science. It is indeed a key substance that cannot be ignored in organic synthetic chemistry.
    Physical & Chemical Properties
    4-Iodoacetophenone is an organic compound. Its physical and chemical properties can be studied. Looking at its color, it often shows a white to light yellow crystalline state, which is observable by the eye. Smell it, there is a specific smell. Its melting point is about 56-58 ° C. When the temperature rises to this point, the state of matter gradually changes, from solid to liquid, a sign of this phase transition.
    When it comes to solubility, it can be soluble in organic solvents such as ethanol and ether, but slightly soluble in water. The difference in solubility is related to the interaction between molecular structure and solvent. Its chemical properties are active, iodine atoms have high reactivity, and can participate in many nucleophilic substitution reactions. In the field of organic synthesis, it is a key intermediate and can derive many compounds, which greatly contributes to the development of organic chemistry.
    Technical Specifications & Labeling
    4 - Iodoacetophenone is an important compound in organic synthesis. Its preparation process is related to the selection of raw materials and the control of reaction conditions. The purity of raw materials has a great impact on product quality. Reaction temperature, duration, catalyst type and dosage are all key parameters. If the temperature is too high, it may cause more side reactions; if the temperature is too low, the reaction rate will be slow. If the time is insufficient, the reaction is difficult to achieve expectations; if it is too long, it may cause the product to decompose.
    The method of detection is commonly used chromatography and spectroscopy. Chromatography can analyze its purity and determine the impurity content. Spectrum can identify its structure to confirm whether it is the target product. In product specifications, the purity must reach a certain standard, and physical parameters such as appearance, melting point, and boiling point should also comply with regulations. Only in this way can we ensure that 4-Iodoacetophenone products are of high quality and suitable for various application scenarios.
    Preparation Method
    4-Iodoacetophenone is an organic compound. To make it, the first thing to know is the raw materials and production process.
    The raw materials are often based on acetophenone and iodine. The production process is related to the reaction steps and catalytic mechanisms.
    The reaction step is to mix acetophenone with appropriate reagents under specific conditions. The benzene ring site of acetophenone can be substituted with iodine with the assistance of a catalyst. The catalyst, or Lewis acid, can promote the reaction and increase the reaction rate.
    Catalytic mechanism, the catalyst can polarize the iodine molecule, making it easier for iodine to react with acetophenone. In this process, precise temperature control, pressure control and reaction time are crucial. If the temperature is too high or side reactions are caused, if it is too low, the reaction will be delayed. In this way, according to this raw material and process, reaction steps and catalytic mechanism, 4-iodoacetophenone can be obtained.
    Chemical Reactions & Modifications
    4-Iodoacetophenone is an organic compound, and its preparation involves specific chemical reactions and modifications.
    In the past, this compound was prepared by conventional chemical methods. The initial reaction often used acetophenone as the starting material, and iodine atoms were introduced by halogenation reaction. However, the traditional method has drawbacks. The reaction conditions may be harsh, requiring high temperature, high pressure or special catalysts, and the selectivity is not good, and there are many side reactions, resulting in product purity and yield that are difficult to achieve ideal.
    Today's chemical research focuses on the optimization and modification of reaction conditions. The development of new catalysts can efficiently catalyze the reaction under mild conditions, greatly improve the reaction selectivity and reduce the generation of by-products. Or explore new reaction paths, guided by the concept of green chemistry, to reduce energy consumption and environmental pollution. After unremitting exploration, the preparation of 4-Iodoacetophenone has become more efficient and environmentally friendly, laying a solid foundation for its wide application in organic synthesis and other fields.
    Synonyms & Product Names
    4-Iodoacetophenone is an important compound in the field of organic synthesis. Its synonyms include p-iodoacetophenone, etc. Trade names may vary from manufacturer to manufacturer.
    This substance is widely used in the chemical industry and can be used as a pharmaceutical intermediate to play a key role in the synthesis of specific drugs. In the field of materials science, it can also be used as a raw material for the preparation of some special performance materials.
    p-iodoacetophenone, its name means that on the basis of the acetophenone structure, the para-position is replaced by an iodine atom. This structural property gives it unique chemical activity. Behind the different trade names, it reflects the different positioning and market strategies of each manufacturer for their products. However, in essence, they are all the core compounds of 4-Iodoacetophenone, whose chemical essence is constant and indispensable for contributions in various fields.
    Safety & Operational Standards
    4 - Iodoacetophenone is an important chemical substance, which is crucial for its safety and operating practices.
    For storage, choose a cool, dry and well-ventilated place. Be sure to keep away from fires and heat sources to prevent danger. This substance should be stored separately from oxidants, food chemicals, etc., and must not be mixed to avoid chemical reactions. The storage area should be equipped with suitable materials to contain leaks to prevent inadvertent leakage from causing harm.
    When operating, operators must be specially trained and strictly follow the operating procedures. It is recommended that operators wear self-priming filter dust masks, chemical safety glasses, anti-poison infiltration overalls, and rubber gloves to ensure their own safety. Keep away from fire and heat sources during operation, and smoking is strictly prohibited in the workplace. Use explosion-proof ventilation systems and equipment to prevent dust from being released into the air of the workshop. Avoid contact with prohibited substances such as oxidizers. When handling, it should be handled lightly to prevent damage to packaging and containers. Equip with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. If a leak occurs accidentally, personnel from the leakage contaminated area should be quickly evacuated to a safe area, and quarantined, strictly restricting access. It is recommended that emergency personnel wear self-contained positive pressure breathing apparatus and anti-toxic clothing. Do not directly contact leaks. Small leaks: Avoid dust, collect it in a dry, clean, covered container with a clean shovel. Large leaks: Cover with plastic cloth and canvas. Then it is collected and recycled or transported to the waste disposal site for disposal.
    Only by strictly adhering to these safety and operating practices can the safety of 4-Iodoacetophenone during use and storage be ensured, and accidents can be avoided.
    Application Area
    4-Iodoacetophenone is also a chemical substance. Its application domain is also important. In the field of synthesis, it can be used as a medium to help the development of various materials, so as to improve the disease. In the field of material science, it also has its application, or can improve the properties of materials and make them more characteristic. In the field of synthesis, it can be used as an important tool for the development of chemical molecules. In addition, 4-Iodoophacetenone plays an important role in the field of synthesis, and its application prospect is indispensable for the study of chemistry.
    Research & Development
    I am committed to the research of 4-Iodoacetophenone. This compound has a unique structure and unique properties, and has great potential in many fields such as organic synthesis.
    At the beginning, explore its preparation methods and try various paths. Or improve the old method, strive to improve the yield, optimize the reaction conditions, and make the process simpler and more efficient; or open up new ways, explore the unknown reaction mechanism with innovative thinking.
    Study its reactivity and observe its role with various reagents. It is found that under specific conditions, it can react delicately with a certain type of nucleophilic reagent, and the product structure is novel, which is expected to be applied to the development of new drugs.
    Looking forward to the future, it will continue to deepen. On the one hand, it expands its application in the field of materials science and explores its impact on material properties; on the other hand, it deepens the understanding of its reaction mechanism and lays the foundation for more accurate synthesis. It is hoped that this will promote the research and development of 4-Iodoacetophenone and contribute to scientific progress.
    Toxicity Research
    Study the toxicity of 4 - Iodoacetophenone. Examine the color and characteristics of this thing in detail. Its taste and smell make it feel special.
    Detect its toxicity with various experiments. When placed on insects, insects move slowly, their bodies curl up, and they die soon, which shows that they have great harm to insects. Try it again with small animals. If the small animals eat it, they will be uneasy, vomit and resist, and their bodies shake and their hair will stand up, and the toxicity is significant.
    Explain the reason for its toxicity, or because of its unique structure, it enters the biological body, disrupts the order of its biochemistry, and disturbs the cells. 4 - The toxicity of Iodoacetophenone is such that when it is used, it must be used with caution to prevent harm to living beings and damage to the surrounding environment.
    Future Prospects
    4-Iodoacetophenone, this compound is gradually emerging in today's chemical research. Looking at its future prospects, it has great potential. We can see it from multiple perspectives.
    It may become a key building block in the field of organic synthesis. With its unique structure, it can lead to novel reaction paths and explore the possibility of creating new compounds. In pharmaceutical research and development, it may be the basis for leading compounds. After exquisite modification, it is expected to breed new drugs with specific effects and save patients from pain.
    There are also opportunities in materials science. With reasonable design, it may be able to give materials specific optical and electrical properties, adding to advanced materials. Although there may be obstacles in the way ahead, scientific exploration is fearless. In time, 4-iodoacetophenone will shine brightly, occupy an important place in the forest of future science and technology, and contribute extraordinary power to human well-being.
    Where to Buy 4-Iodoacetophenone in China?
    As a trusted 4-Iodoacetophenone manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Iodoacetophenone supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-iodoacetophenone?
    4-Iodoacetophenone, or 4-iodoacetophenone, has a wide range of main uses. In the field of organic synthesis, it is often used as a key intermediate.
    Cover because of its structure, iodine atoms and acetophenone groups have unique chemical activities. Iodine atoms can participate in many nucleophilic substitution reactions, through which chemists can introduce various functional groups. For example, in palladium-catalyzed cross-coupling reactions, 4-iodoacetophenone can react with carbon-containing nucleophiles to form carbon-carbon bonds, and then synthesize more complex organic molecules, which is of great significance in medicinal chemistry and materials science.
    In the field of drug development, 4-iodoacetophenone also plays an important role. By ingeniously modifying its structure, compounds with specific biological activities can be obtained. Medicinal chemists often use this as a starting material to design and synthesize new drug molecules through multi-step reactions to explore their potential for disease treatment.
    In addition, in the field of materials science, polymers or functional materials based on the synthesis of 4-iodoacetophenone may exhibit special physical and chemical properties. For example, it can be used to prepare materials with specific optical and electrical properties, and can be used in optoelectronic devices.
    In summary, 4-iodoacetophenone has important uses in many fields such as organic synthesis, drug development, and materials science due to its unique chemical structure, providing a key starting material and synthesis intermediate for many scientific research and industrial applications.
    What are the synthesis methods of 4-iodoacetophenone?
    4-Iodoacetophenone, that is, 4-iodoacetophenone. There are several common methods for synthesis.
    First, acetophenone is used as the starting material and can be obtained by halogenation reaction. Put acetophenone in a suitable reaction vessel, add an appropriate amount of halogenating reagents, such as iodine and an appropriate catalyst. Common catalysts include iron powder, ferric trichloride, etc. Under a certain temperature and reaction time, the hydrogen atom on the benzene ring of acetophenone can be replaced by the iodine atom to generate 4-iodoacetophenone. When reacting, it is necessary to pay close attention to the control of temperature, because the temperature is too high, or the formation of polyhalogenated by-products; if the temperature is too low, the reaction rate will be slow and the yield will be low.
    Second, it can be started from 4-acetylbenzoic acid. First, 4-acetylbenzoic acid undergoes an appropriate reduction reaction to convert its carboxyl group into other easy-to-leave groups, such as alcohol hydroxyl groups, and strong reducing agents such as lithium aluminum hydride can be used. After that, it undergoes a substitution reaction with the iodizing reagent to introduce iodine atoms, and finally through appropriate treatment, 4-iodoacetophenone is obtained. In this process, the conditions of the reduction reaction and the substitution reaction need to be precisely regulated to ensure the smooth progress of each step of the reaction and a high yield.
    Third, the Fu-gram acylation reaction of benzene and acetyl chloride is first carried out to generate acetophenone, and then the halogenation reaction is carried out as described above to introduce iodine atoms. For the Fu-gram acylation reaction, a suitable Lewis acid catalyst, such as anhydrous aluminum trichloride, is selected, and the reaction system needs to be kept anhydrous and oxygen-free to prevent catalyst failure and side reactions. Subsequent halogenation conditions also need to be carefully considered in order to synthesize high-purity 4-iodoacetophenone.
    What are the physical properties of 4-iodoacetophenone?
    4-Iodoacetophenone is an organic compound. It has unique physical properties and is widely used in the field of chemistry.
    Looking at its properties, it usually shows a white to light yellow crystalline powder state, which is easy to identify and operate. Its melting point range is about 57-60 ° C, and the characteristics of the melting point are of great significance in the identification and purity judgment of the compound. When the temperature rises to the melting point, 4-iodoacetophenone gradually melts from a solid state to a liquid state. This transformation follows the laws of physics and can be determined by accurate temperature measurement.
    As for the boiling point, it is about 280 ° C. The boiling point reflects the energy required for the compound to convert from a liquid state to a gas state under a specific pressure. This value provides a key reference for its application under different reaction conditions, because the high temperature environment or its gasification process affects the process and result of the reaction.
    The density of 4-iodoacetophenone is about 1.896 g/cm ³. Density is an inherent property of the substance, which is related to its distribution and behavior in solution or mixed system. In some experiments and production processes involving phase separation or solution preparation, density considerations are indispensable.
    In terms of solubility, it is slightly soluble in water, but soluble in most organic solvents, such as ethanol, ether, chloroform, etc. This solubility property allows 4-iodoacetophenone to participate in various chemical reactions in the medium of different organic solvents, greatly expanding its application range. In the field of organic synthesis, its solubility can be used to select suitable solvents to optimize reaction conditions and promote efficient reaction.
    In addition, 4-iodoacetophenone has a certain degree of volatility. Although the volatility is not strong, it should also be paid attention to in poorly ventilated environments. Because it is an organic compound and flammable, it is necessary to follow safety regulations when storing and using it, and keep it away from ignition sources and high temperatures to ensure safe operation. Its many physical properties are interrelated, which together determine the role and use of 4-iodoacetophenone in chemical research and industrial production.
    What are the precautions for 4-iodoacetophenone during storage and transportation?
    4-Iodoacetophenone is an organic compound, and all matters need to be paid attention to during storage and transportation.
    First, store, this substance should be placed in a cool, dry and well-ventilated place. Because it is quite sensitive to light, it should be stored in a shaded container to prevent it from decomposing or deteriorating due to light. Temperature is also critical. Excessive temperature may accelerate its chemical reaction and cause quality damage, so it should be controlled in an appropriate low temperature range. At the same time, it should be stored separately from oxidizing agents, acids, bases, etc., because 4-iodoacetophenone or reacts violently with it, which may cause safety risks. And the storage area should be equipped with suitable containment materials to prevent accidental leakage from being dealt with in time.
    As for transportation, it is necessary to ensure that the packaging is complete and sealed. The transportation process must be shock-proof, moisture-proof, and sun-proof to prevent material leakage due to package damage. Transportation vehicles should be equipped with corresponding fire-fighting equipment and leakage emergency treatment equipment, and transportation personnel should also be familiar with the nature of 4-iodoacetophenone and emergency treatment methods. During transportation, the relevant regulations on the transportation of hazardous chemicals should also be strictly followed, and they should be driven according to the designated route, away from densely populated areas and fire sources.
    After all, whether it is storing or transporting 4-iodoacetophenone, it is necessary to be careful and strictly follow relevant norms and requirements to ensure personnel safety, environmental safety and material quality.
    What is the market price of 4-iodoacetophenone?
    4-Iodoacetophenone is an organic compound, Chinese name 4-iodoacetophenone. Its market price often fluctuates due to many factors such as purity, supply, purchase volume and market supply and demand, so it is difficult to give an exact price.
    If you buy a small amount of high purity (such as more than 98%) 4-iodoacetophenone from a chemical reagent supplier, the price per gram may range from tens of yuan to 100 yuan according to the commonly used specifications in the laboratory, such as 5g or 10g packaging. This is because the preparation of reagent-grade products requires a strict purification process, which is costly.
    If it is industrial grade, the purity is slightly lower, and the purchase volume is large, such as kilogram grade or above. Due to the scale effect, the price per gram may be greatly reduced to a few yuan to a dozen yuan. During large-scale production, factors such as raw material procurement cost and production efficiency reduce the unit cost.
    However, the market is changing rapidly. If the price of raw material iodine or related chemical raw materials fluctuates sharply recently, the price of 4-iodoacetophenone will also change accordingly. And different regions will have different selling prices due to differences in transportation costs and market competition. To know the exact market price, you need to inquire from relevant chemical product suppliers and distributors in real time, or refer to the quotation information of the chemical product trading platform.