4-Iodobenzenesulfonyl Chloride

Fengxi Chemical

Specifications

HS Code	825473
Chemical Formula	C6H4ClIO2S
Molar Mass	320.417 g/mol
Appearance	White to off - white solid
Melting Point	76 - 78 °C
Boiling Point	Decomposes
Solubility In Water	Reacts with water
Solubility In Organic Solvents	Soluble in many organic solvents like dichloromethane, chloroform
Density	N/A (solid, density determination methods vary)
Hazard Class	Corrosive, harmful if swallowed, in contact with skin or if inhaled
Chemical Formula	C6H4ClIO2S
Molecular Weight	316.517 g/mol
Appearance	White to off - white solid
Melting Point	73 - 75 °C
Boiling Point	N/A (decomposes)
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Density	N/A
Odor	Pungent odor
Reactivity	Reactive towards nucleophiles, can be used in sulfonylation reactions
Hazard Class	Corrosive, causes burns to skin, eyes and respiratory tract

As an accredited 4-Iodobenzenesulfonyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 4 - iodobenzenesulfonyl chloride packaged in a sealed glass bottle.
Storage	4 - Iodobenzenesulfonyl Chloride should be stored in a cool, dry, well - ventilated area, away from heat sources and direct sunlight. Keep it in a tightly - sealed container to prevent moisture and air exposure, as it can react with water. Store it separately from incompatible substances like bases, reducing agents, and moisture - sensitive materials to avoid potential reactions.
Shipping	4 - iodobenzenesulfonyl chloride is a chemical. Shipping should be in accordance with regulations for hazardous chemicals. It must be properly packaged to prevent leakage, with clear labels indicating its nature, and transported by approved carriers.

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General Information

Historical Development

4-Iodobenzenesulfonyl chloride is also an important agent in organic synthesis. Its origin originated when chemical technology was gradually improving, and many people studied new substances, and made deep efforts in organic sulfonyl chlorine.
At that time, scholars were eager for knowledge and explored the preparation of various halogenated benzenesulfonyl chlorides. After years of research, iodobenzene was used as a base, supplemented by chlorination, and 4-iodobenzenesulfonyl chloride was finally obtained. At the beginning, the preparation method was complicated, and the yield was not abundant.
However, science and technology have evolved, and the preparation process has become increasingly exquisite. Chemical craftsmen optimize the process, improve the conditions, and the yield gradually increases, and the quality is better. The application of this compound in medicine, materials and other fields has also gradually expanded, opening up new avenues for many scientific research and industries, and adding a bright chapter to the long river of chemical development.

Product Overview

4-Iodobenzenesulfonyl Chloride is an important compound in organic synthesis. Its color is light yellow to light brown, and it is crystalline. It has a stimulating odor and is easy to react with water.
This compound has a wide range of uses in the field of organic chemistry. It is often used as a sulfonylation reagent and can introduce sulfonyl groups in many reactions. For example, in the process of synthesizing specific drug intermediates, it can react with compounds containing active hydrogen to form sulfonamides, which are of great significance in drug development.
Furthermore, in the field of materials science, it participates in the preparation of some functional materials, giving materials unique properties through chemical reactions. However, caution is required when using this compound, as it is corrosive and irritating. It should be handled in a well-ventilated environment and safety procedures should be strictly followed to prevent harm to personnel and the environment.

Physical & Chemical Properties

4-Iodobenzenesulfonyl Chloride is an organic compound, and its physical and chemical properties are of great research value. Looking at its physical properties, it is mostly solid at room temperature, white or white, with a certain melting point, and melts into a liquid state when heated to a specific temperature. This property is quite useful when separating and purifying. Its chemical properties are active, and sulfonyl chloride groups easily react with many nucleophiles. It is easy to hydrolyze in water, and sulfonyl chloride groups will be converted into sulfonic acid groups, and hydrogen chloride will be released at the same time. When reacted with alcohols, sulfonate esters can be formed, which is often used in the field of organic synthesis to construct compounds with specific structures. Its iodine atoms can also participate in a variety of coupling reactions, providing a way for the synthesis of complex organic molecules, which has important applications in pharmaceutical chemistry and materials science.

Technical Specifications & Labeling

4-Iodobenzenesulfonyl chloride is an important substance in chemical research. Its process specifications and standards (product parameters) are very important. To observe its preparation, it is necessary to follow a rigorous process. The selection and ratio of raw materials, the temperature and duration of the reaction are all determined. The reaction environment must be pure to prevent impurities from mixing.
In terms of product characterization, various means are used to identify. Taking the melting point determination as an example, its purity can be observed. If the melting point matches the standard value, it indicates that the purity is good. Infrared spectroscopy is also a powerful tool, and the absorption peak of a specific functional group can determine its structure. By precisely controlling the process specifications and strictly characterizing and identifying, high-quality 4-iodobenzenesulfonyl chloride products can be obtained to meet the needs of scientific research and industry.

Preparation Method

4-Iodobenzenesulfonyl Chloride is an important chemical substance, and its preparation method is crucial. In the preparation of raw materials, iodobenzene and related sulfonating reagents are often used as the starting point. The sulfonation process requires precise control of the reaction conditions.
At the beginning of the reaction step, place iodobenzene and specific sulfonating reagents in a suitable reaction vessel in a certain proportion. Heat and stir to maintain a specific temperature to make the two fully react. This reaction process needs to be closely monitored to prevent side reactions from occurring.
In terms of catalytic mechanism, the selection of high-efficiency catalysts can accelerate the reaction process. Specific metal salts or organic bases are often used as catalysts, which can reduce the activation energy of the reaction and improve the reaction efficiency.
During the preparation process, the precise control of the reaction temperature, time and the proportion of raw materials is the key to obtaining high-purity 4-Iodobenzenesulfonyl Chloride. In this way, according to this rigorous preparation method, the high-quality chemical product can be obtained.

Chemical Reactions & Modifications

4-Iodobenzenesulfonyl Chloride is an important chemical substance. Its chemical reactions are changeable and involve many chemical processes. In terms of its chemical properties, it can often react delicately with a variety of reagents, and the results of this reaction have a profound impact on the characteristics of the product.
Previous studies have mostly focused on optimizing the reaction conditions to improve the purity and yield of the product. To improve its reaction characteristics, you can start from multiple ends. First, the reaction temperature and pressure are finely regulated, and the reaction may be more ideal under suitable temperature and pressure conditions. Second, the catalyst is carefully selected, and the appropriate catalyst can significantly change the rate and direction of the chemical reaction.
Furthermore, the properties of the reaction solvents cannot be underestimated, and the effects of different solvents on the reaction vary widely. Through in-depth investigation and reasonable adjustment of these factors, 4-Iodobenzenesulfonyl the chemical reaction of Chloride will be able to reach a better state, and the product characteristics are expected to be further optimized.

Synonyms & Product Names

Today there is a thing named 4 - Iodobenzenesulfonyl Chloride. Its synonymous name is also important in the academic world. This thing is often a key material in chemical research.
The name of the husband is synonymous, so it is the title of the scholar to help him communicate with each other in his research without confusion. This 4 - Iodobenzenesulfonyl Chloride, or another name, all refer to the same thing. Merchants are in the city, and they also sell it under various commodity names, but its essence is the same thing.
We are researchers of chemistry. When we understand its synonymous name and trade name, we can be accurate and correct in experiments and studies, so as to make academic progress and technical excellence.

Safety & Operational Standards

4-Iodobenzenesulfonyl chloride
4-Iodobenzenesulfonyl chloride is a chemical commonly used in chemical research. In order to ensure the safety and smooth progress of the experiment, it is necessary to know its safety and operation standards.
This chemical is dangerous. It is corrosive. If it comes into contact with the skin accidentally, it should be washed with a lot of water immediately, followed by dilute sodium bicarbonate solution. In severe cases, medical attention is required. If it splashes into the eyes, it is even more dangerous. Immediately open the eyelids and rinse thoroughly with a large amount of flowing water or normal saline. Be sure to seek medical attention promptly.
During the operation, a well-ventilated experimental environment should be selected, and it is best to operate in a fume hood to avoid the accumulation of harmful gases. Experimenters need to wear protective clothing, protective gloves and goggles, and be fully armed to ensure their own safety.
When taking 4-iodobenzenesulfonyl chloride, the action must be gentle to prevent its spillage. If there is any spillage, it should be dealt with in a suitable manner immediately. A small amount of spillage can be mixed with sand, dry lime or soda ash first, and then collected in a dry, clean and covered container. If a large amount of spillage is scattered, it needs to be built into a dike or dug for containment, and transferred to a tanker or a special collector by pump, recycled or transported to a waste disposal site for disposal.
Storage should also be cautious. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, and stored separately from oxidants and alkalis. Do not store mixed.
In short, the operation of 4-iodobenzenesulfonyl chloride must always be rigorous and strictly abide by safety and operating standards, so as to ensure the safety of experiments and promote the smooth development of scientific research.

Application Area

4-Iodobenzenesulfonyl chloride is a good chemical product. Its application field is quite wide. In the field of organic synthesis, it is often a key reagent. With its unique structure, it can react with many compounds to obtain other difficult-to-obtain products.
In pharmaceutical research and development, it is also important. Or through clever reaction paths, special groups can be introduced to lay the foundation for the creation of novel drug molecules and help overcome difficult diseases.
In material science, with its reactive properties, the surface of materials can be modified to improve the properties of materials, such as enhancing their stability and improving their adsorption properties. Therefore, 4-iodobenzenesulfonyl chloride has shown its value in many application fields, providing many possibilities for chemical research and related industry development.

Research & Development

In recent years, I have focused on the research of chemical products, especially 4-Iodobenzenesulfonyl Chloride. This material property is special, and its effectiveness is quite different in various chemical reactions.
At the beginning, the study of its manufacturing process, the selection of raw materials and the control of conditions, all need to be carefully reviewed. After several trials and errors, a better method can be obtained, and the yield gradually increases.
Then study its application, in the field of organic synthesis, it can be used as a key reagent, the formation of special bonds, and the development of new chemical pathways. After joint exploration by colleagues, it is used to form new compounds with potential medicinal and material value.
Looking to the future, I hope to be able to dig deep into its properties and expand its application domain. Optimize the production method, reduce costs and improve efficiency, and make more significant progress in the pharmaceutical and material industries, opening up a new path for chemical research and achieving a higher level.

Toxicity Research

The chemical industry is related to people's livelihood, but the study of poisons must not be careless. Today, in the case of 4-Iodobenzenesulfonyl Chloride, the study of its toxicity is of paramount importance.
This substance has strong irritation, touches the skin, or causes burning, redness and swelling, and hurts the eyes and is very harmful. If you inhale its qi, your lungs and organs will be invaded, and you may develop symptoms such as cough and shortness of breath. And long-term exposure may cause serious illness and damage to your organs.
Therefore, when studying its toxicity, you must follow ancient methods to observe the changes in its contact with the body and explore the harm of the body. Protective measures should not be ignored. Wear special clothes, goggles and masks to avoid its damage. Researchers should be in awe and cautious to ensure their own safety and promote the prosperity of the chemical industry.

Future Prospects

4-Iodobenzenesulfonyl Chloride, it is also the material of transformation. I have studied and researched it, and I hope it is not yet done. This object has the field of synthesis, and the material has extraordinary performance. It can be used to develop the important angle of the structure, its special activity, and more subtle reactions, or to make the synthesis road faster and more efficient. And in the process of material research, or it is an important task, to help the new type of technology, and to add more tiles to the health care. It is in the material science, or the new characteristics of the material, to promote the material innovation. In the future, 4-Iodobenzenesulfonyl Chloride will be used in many fields, and it will be possible to expand its potential, which will demonstrate its significant value.

Historical Development

4-Iodobenzenesulfonyl chloride is also a chemical product. The historical evolution of its matter can be studied. In the past, chemical sages worked tirelessly on the path of material exploration. At the beginning, the understanding of sulfonyl chloride compounds was still shallow, and only a little bit of their basic properties were known. However, over the years, everyone gradually understood its reaction characteristics. As for 4-iodobenzenesulfonyl chloride, after many experiments, scholars have explored the synthesis method. From the initial exploration to the gradual maturation of the process, this process is full of hardships. Early synthesis, the yield was meager, and the purity was also low. However, the public was not discouraged, and after repeated improvement, the conditions were optimized, so that the synthesis efficiency was improved and the quality was also excellent. This product has become increasingly important in the field of organic synthesis, and has played a role in drug research and development, material creation, etc. Its historical evolution is a witness to the development of chemistry.

Product Overview

"Description of 4-Iodobenzenesulfonyl Chloride"
4-Iodobenzenesulfonyl chloride is an important chemical product in organic synthesis. Its color is white to yellowish, and it is often crystalline. In the field of organic reactions, it has a wide range of uses.
Looking at its structure, iodine and sulfonyl chloride groups on the benzene ring are cleverly connected. This structure gives it unique chemical activity. In many nucleophilic substitution reactions, sulfonyl chloride groups easily interact with nucleophiles to form novel compounds. Iodine atoms are not idle, and can participate in metal-catalyzed coupling reactions to help build more complex organic molecular structures.
In the industrial preparation process, through specific reaction steps and careful regulation of reaction conditions, such as temperature, pH, reactant ratio, etc., high-purity 4-iodobenzenesulfonyl chloride can be obtained. It is used in medicinal chemistry, materials science and other fields to provide key raw materials for the synthesis of substances with specific properties.

Physical & Chemical Properties

4-Iodobenzenesulfonyl Chloride, the organic compound is also. Its physical properties are solid at room temperature, white or white, with a certain melting point, depending on the force between molecules. Its odor is pungent, and its structure contains special functional groups.
In terms of its chemical properties, the sulfonyl chloride group is active and easy to react with nucleophiles. It is hydrolyzed in contact with water, and the sulfonic acid and hydrogen chloride are common chemical changes. The iodine atom on the benzene ring also participates in the reaction and can undergo various transformations such as substitution. It has a wide range of uses in the field of organic synthesis. It is often a key raw material for the construction of complex organic molecules. It helps chemists prepare a variety of compounds to meet the different needs of medicine and materials.

Technical Specifications & Labeling

4-Iodobenzenesulfonyl chloride is also a chemical preparation. Its process specifications are related to the choice of raw materials. Those that are pure must be selected, and impurities must be fine. The temperature of the reaction should be stable in a certain area. If it is too high, the quality will change easily, and if it is too low, it will be difficult to achieve. The duration also needs to be accurate. If it is less, it will not be fully applied, and if it is more, it will be unhealthy.
Its product logo is on the packaging, and the name of the book is "4-benzenesulfonyl chloride". The molecular formula and molecular weight are listed in detail. The standard of purity must reach a certain value to prove the excellence of quality. Character description, color, state clear, and shows the need for storage, heat and moisture, stored in a cool place, so as to maintain its stability, in line with commercial regulations, for all experiments, production needs.

Preparation Method

To prepare 4 - Iodobenzenesulfonyl Chloride, the first choice of raw materials. When taking benzenesulfonic acid as the initial material, add an appropriate amount of potassium iodide, and the two are mixed with suitable solvents, such as dichloromethane, as the basis for raw materials.
The method of preparation is to first place benzenesulfonic acid and potassium iodide in a reactor, slowly inject dichloromethane, so that the two are fully miscible. Then, in a low temperature environment, about 0 to 5 degrees Celsius, add thionyl chloride dropwise. When adding dropwise, the reaction state should be closely monitored to avoid overreaction. The amount of thionyl chloride should be precisely prepared according to the amount of benzenesulfonic acid to achieve the best reaction ratio.
When the thionyl chloride is added dropwise, heat up to room temperature, and continue to stir, so that the reaction can be fully carried out. During this process, the change of the reaction system needs to be paid attention to from time to time. After about a few hours, the reaction gradually becomes complete. Then by vacuum distillation, the solvent and unreacted thionyl chloride are removed to obtain a crude product. After
, the crude product is purified by column chromatography, and a suitable eluent, such as a mixture of petroleum ether and ethyl acetate, is prepared in proportion to make the product pure. In this way, 4-Iodobenzenesulfonyl Chloride with high purity can be obtained. The whole preparation process, the raw materials and the process are coordinated, the reaction steps are orderly, and the control mechanism is appropriate, so that this product can be obtained.

Chemical Reactions & Modifications

In the field of chemistry, its reaction and modification are the key.
Looking at its reaction, when it encounters various reagents, it often changes wonderfully. Or in response to nucleophilic reagents, sulfonyl chloride is easy to change to his group, forming a novel structure. This reaction is also very important under the control of conditions, and the temperature, time, and proportion of agents can all affect its fruit.
When it comes to modification, in order to increase its activity or change its properties, chemical methods are often applied. Or introduce special groups to change its physical and chemical properties to suit diverse needs. Such as adjusting its solubility and stability to make it better in specific environments.
In this way, the chemical reaction and modification of 4-Iodobenzenesulfonyl Chloride is the focus of scientific research, hoping to gain new knowledge and expand the boundaries of chemical applications.

Synonyms & Product Names

Wenfu 4 - Iodobenzenesulfonyl Chloride This product may have another name. Looking at the field of chemical industry, there are many people who have the same product but different names. This agent is also called by the name of sulphur halide, or from the structure of its iodobenzenesulfonyl chloride.
In the course of experiments, the names used by various families vary. Either according to the source of its preparation, or according to the nature of its reaction, the names are different. However, its quality is the same, and it is all this specific compound.
Although the names are different, its properties and uses can be obtained by testing. Chemists should understand their essence and not be confused by the name, in order to achieve accurate use and seek progress for scientific research and industry.

Safety & Operational Standards

4-Iodobenzenesulfonyl chloride is also used as a preparation. It is crucial to the safety and operation standards of this substance.
4-Iodobenzenesulfonyl chloride is highly corrosive and will cause damage if it touches the skin and eyes. Therefore, when handling, you must wear protective clothing, protective goggles and gloves to avoid contact with the body and skin. If you accidentally touch it, rinse it with plenty of water quickly and seek medical treatment.
Its gas is also irritating, and it is appropriate to operate it in a well-ventilated place. If there is no ventilation equipment, wear a gas mask to avoid inhaling its gas and causing respiratory discomfort.
Furthermore, 4-iodobenzenesulfonyl chloride may be at risk of ignition and explosion under certain conditions. Therefore, keep away from fire and heat sources, store in a cool, dry and ventilated place, and separate from flammable and combustible materials.
During the operation process, precise temperature control, time control and material ratio should be carried out according to the standard process. After use, properly store the residue, and do not dispose of it at will to prevent pollution and environmental damage.
In short, the operation of 4-iodobenzenesulfonyl chloride must strictly follow safety and operating specifications to ensure its own safety and protect the environment. In this way, this material can be used safely and appropriately in chemical research and other fields.

Application Area

4-Iodobenzenesulfonyl chloride is also a chemical product. Its application field is quite wide. In the field of medicine, it can be used as a key intermediate to help the research and development of new drugs. With its special structure, it can participate in various reactions to obtain compounds with specific activities, which adds to the path of healing.
In materials science, it also has its uses. It can be introduced into the material structure through chemical reactions, giving new properties to the material, such as improving the stability and conductivity of the material, and promoting the development of the material field.
In the field of organic synthesis, 4-iodobenzenesulfonyl chloride is a powerful tool. With its unique reactivity, it can realize the construction and modification of a variety of organic molecules, expand the boundaries of organic synthesis, and open up new paths for the study of organic chemistry.

Research & Development

Today there is a product named 4 - Iodobenzenesulfonyl Chloride. We are chemical researchers and have been studying it for a long time. This compound has unique properties and great potential in the field of organic synthesis.
At the beginning, its structure and reaction characteristics were explored, and after many experiments, its reaction law was clarified. Later, to expand its application, we tried different reaction conditions to observe its performance in various synthesis paths.
After long-term efforts, we have made breakthroughs in the synthesis of pharmaceutical intermediates, and with its characteristics, we have made several potential intermediates. And optimize the synthesis process, improve the yield and purity, and lay the foundation for its large-scale production.
Looking to the future, we hope to further expand its use and make achievements in the fields of materials science, promoting this compound from research to wider practical applications and promoting the development of the chemical field.

Toxicity Research

Those who have studied chemical substances in recent times have focused on the toxicity study of 4-Iodobenzenesulfonyl Chloride. This compound has a specific appearance and is also active. It often shows a unique state in various chemical reactions.
Study its toxicity, which is related to the health of living beings and the safety of the environment. If you accidentally touch it, or enter the body through the skin, or take it in by breathing, it can be harmful. In light cases, you feel uncomfortable, such as dizziness and nausea; in severe cases, you may damage your organs, endangering your life.
And it is also potentially dangerous in the environment. If it flows into the water source, it is afraid that the sewage body will harm the aquatic spirit; if it is scattered in the atmosphere, it will also disturb the cleanliness of the air and harm all living beings. Therefore, when researching and using this product, we should be careful to prevent toxicity and ensure people's safety and peace.

Future Prospects

I 4-Iodobenzenesulfonyl Chloride, which has revealed extraordinary clues in the field of current chemistry. Although only one or two of its characteristics and reactions have been explored today, I look to the future, and its prospects should be like a vast sky and boundless.
In the future, it is expected that in the industry of organic synthesis, 4-Iodobenzenesulfonyl Chloride will become a key agent. With its unique structure, it may open up new synthetic paths and pave the way for the creation of novel compounds. In the way of pharmaceutical research and development, it may be used to develop special drugs to relieve patients' pain. In the field of materials science, it may also use its strength to develop new materials with excellent performance to meet diverse needs.
I am convinced that with time and in-depth study, 4-Iodobenzenesulfonyl Chloride will be able to shine, leaving a strong pen in the future of scientific development, adding luster to human well-being.

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Frequently Asked Questions

As a leading 4-Iodobenzenesulfonyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-iodobenzenesulfonyl Chloride?

4-Iodobenzenesulfonyl chloride is a crucial chemical reagent in the field of organic synthesis. It has a wide range of uses and is mainly applied to the following ends.
First, in the field of medicinal chemistry, it can be used as a key intermediate to construct drug molecules with specific physiological activities. Due to its unique structure, it can introduce iodine atoms and benzenesulfonyl groups by reacting with various compounds containing active hydrogen or nucleophilic groups. This digroup is of great significance in the design of drug molecules. Iodine atoms can adjust the lipid solubility and electron cloud density of molecules, affecting the interaction between drugs and targets; benzenesulfonyl groups can participate in the formation of hydrogen bonds, or affect the spatial conformation of molecules, enhancing the stability and activity of drugs. For example, in the synthesis of some antibacterial and anti-inflammatory drugs, 4-iodobenzenesulfonyl chloride plays an indispensable role in the synthesis of molecular structures with precise pharmacological activity.
Second, in the field of materials science, it also has important uses. It can be used to prepare functional polymer materials, and its structure can be introduced into the polymer main chain or side chain by reacting with compounds containing double bonds or other polymerizable groups. In this way, the prepared polymer material has the special properties conferred by iodine and benzenesulfonyl groups. Such as improving the electrical and optical properties of the material, or enhancing its chemical stability and surface properties. In the research and development of electronic devices, optical films and other materials, this characteristic can effectively optimize the comprehensive properties of the material and meet the needs of different fields for special properties of the material.
Third, in many reactions in organic synthesis chemistry, 4-iodobenzenesulfonyl chloride is often the key raw material for the synthesis of special structural organic compounds. If reacted with amine compounds, sulfonamide compounds can be prepared, which are important structural units in organic synthesis and medicinal chemistry; reacted with alcohols to generate sulfonate esters, which are also commonly used intermediates in organic synthesis reactions. They can further participate in various nucleophilic substitution, elimination and other reactions, providing an effective way to construct complex organic molecular structures.

What are the physical properties of 4-iodobenzenesulfonyl Chloride?

4-Iodobenzenesulfonyl chloride, its physical properties are as follows:
This substance is mostly white to light yellow crystalline at room temperature, and the texture is like a fine powder or block. Looking at it, the color is pure, there is no variegated mottles, the crystal structure is regular, and it is often clustered by small particles. Smell it, there is a pungent smell, this smell is sharp and strong, and the smell is uncomfortable, like spicy gas hitting the nasal cavity, stimulating the senses.
Its melting point is about 64-67 ° C. When the temperature gradually rises to the melting point range, this substance slowly melts from solid to liquid, just like ice and snow melting in the warm sun. The boiling point is at 150-152 ° C/1.33kPa. When the temperature and pressure are set, the liquid substance rapidly boils and turns into a gaseous state.
4-iodobenzenesulfonyl chloride has a high density. Compared with common liquids, it is placed in the same container and often sinks at the bottom. It is insoluble in water and meets water. It is as distinct as oil and water, and it is difficult to blend. However, it can be better dissolved in organic solvents, such as dichloromethane, chloroform, ether, etc., just like salt is integrated into water, evenly dispersed and missing.
When storing and using, due to its pungent odor and active chemical properties, it should be properly sealed and stored in a cool and dry place, away from fire sources and oxidants. When using, it should also be handled with caution to prevent accidents.

4-iodobenzenesulfonyl Chloride chemically stable?

4-Iodobenzenesulfonyl chloride is an important compound in organic chemistry. Its chemical properties are not completely stable.
In general environments, 4-iodobenzenesulfonyl chloride is very easy to react with water. The activity of the sulfonyl chloride group is quite high, and when water meets it, it is easy to hydrolyze. When hydrolyzed, the sulfonyl chloride group will be converted into a sulfonate group, and hydrogen chloride gas will be released at the same time. This reaction is rapid and irreversible. Looking at the experimental records in the past, every time it is seen in humid air, there is a significant change in a short period of time, which proves that it is sensitive to water.
Furthermore, 4-iodobenzenesulfonyl chloride is also quite sensitive to heat. When heated, the chemical bonds in the molecule are prone to rearrangement or decomposition. When the temperature rises to a certain level, the iodine atom may break away from the benzene ring, or the sulfonyl chloride group will further decompose, forming a variety of complex products. In the past, experiments have been conducted to investigate its stability by heating means. At a slightly higher temperature, the product is complex and difficult to measure, and it can be known that its thermal stability is poor.
However, under dry and low temperature storage conditions, 4-iodobenzene sulfonyl chloride can maintain a relatively stable state for a certain period of time. However, even so, it must be handled with caution to prevent environmental factors from quietly affecting its chemical structure and properties. Overall, the chemical properties of 4-iodobenzenesulfonyl chloride are not very stable, and special attention should be paid to the influence of many environmental factors during use and storage.

What are the synthesis methods of 4-iodobenzenesulfonyl Chloride?

There are many ways to synthesize 4-iodobenzenesulfonyl chloride. First, it can be obtained by the interaction of 4-iodobenzenesulfonyl acid with chlorination reagents. Phosphorus pentachloride, sulfinyl chloride, etc. are often used as chlorination agents. Take phosphorus pentachloride as an example. The two react with each other in a suitable reaction vessel under appropriate temperature and reaction conditions. The hydroxyl group in 4-iodobenzenesulfonyl acid is replaced by a chlorine atom to generate 4-iodobenzenesulfonyl chloride. This process requires attention to the regulation of the reaction temperature. If the temperature is too high or too low, it can affect the yield and purity of the product.
Second, benzene is used as the starting material. First, through a sulfonation reaction, a sulfonic acid group is Subsequently, an iodine-substituted reagent is used to make an iodine-substituted reaction at a specific position on the benzene ring to obtain 4-iodobenzenesulfonic acid. After the above chlorination step, the target product 4-iodobenzenesulfonic acid chloride is obtained. This route is slightly complicated, but the raw materials are easy to obtain and properly operated, and a higher yield can also be obtained.
Or, with 4-iodoaniline as the starting material, it is converted into 4-iodobenzenesulfonic acid through diazotization reaction, and then converted into 4-iodobenzenesulfonic acid with sodium sulfite, and then chlorinated to generate 4-iodobenzenesulfonic acid chloride. This path requires precise control of the conditions of the diazotization reaction. Due to its high re
All synthesis methods have their own advantages and disadvantages. In actual operation, it is necessary to weigh and choose according to factors such as raw material availability, cost, yield and purity requirements to achieve the best synthesis effect.

4-iodobenzenesulfonyl Chloride in Storage and Transportation

4-Iodobenzenesulfonyl chloride is a chemical substance. When storing and transporting it, all kinds of matters must not be ignored.
Store first. This material is more active and easy to react in contact with water, so it must be stored in a dry place. It must be kept away from water sources and humid places to prevent its deterioration. In the warehouse, the air should be dry and the humidity should be controlled at a low level. And it is sensitive to heat, under high temperature, or dangerous, so it should be stored in a cool place, the temperature should be maintained in a specific range, and the warehouse temperature should not be too high. And because it is corrosive and toxic, it should be stored separately, and it should not be mixed with other things to prevent interaction and accidents. And it must be clearly marked, indicating its characteristics and hazards, so that the relevant parties can know at a glance.
As for transportation, extreme caution is also required. Containers must be corrosion-resistant and airtight to ensure that there is no risk of leakage during transportation. Transportation vehicles should be clean and dry, away from fire and heat sources. Transportation personnel should also be familiar with their characteristics and emergency response methods. In case of an accident, they can respond quickly. The loading and unloading process must be handled with care to avoid collisions and vibrations to prevent damage to the container. And the transportation route should be properly planned, away from densely populated places and water sources to ensure safety.
In short, the storage and transportation of 4-iodobenzenesulfonyl chloride is related to safety, and everything needs to be done in accordance with regulations, and there should be no slack.