4 Iodobenzohydrazide

4-Iodobenzoyl hydrazide, an organic compound. It has a wide range of uses and is often used as a key intermediate in the field of drug synthesis. Due to the properties of the benzene ring and the iodine atom, it can connect different groups through chemical reactions to help build molecular structures with specific pharmacological activities, and then develop various new drugs.
In the field of materials science, it also has its uses. Polymer materials can be introduced through specific reactions to give materials unique properties, such as changing the optical and electrical properties of materials, laying the foundation for the development of novel functional materials.
Furthermore, in the study of organic synthetic chemistry, 4-iodobenzoyl hydrazide, as an important reagent, can participate in a variety of reactions, such as the formation of carbon-carbon bonds, carbon-heteroatomic bonds, etc., helping organic chemists create complex organic molecules and expand the types and applications of organic compounds.
In summary, 4-iodobenzoyl hydrazide has important uses in many fields such as drugs, materials and organic synthesis, and is of great significance to promote the development of related fields.

The synthesis of 4-iodobenzoyl hydrazide has been known for a long time. One method uses 4-iodobenzoic acid as the starting material and first reacts with dichlorosulfoxide to form 4-iodobenzoyl chloride. This step needs to be carried out under the protection of suitable temperature and inert gas to avoid side reactions. 4-iodobenzoyl chloride has high activity, and then reacts with hydrazine hydrate and is replaced by nucleophilic substitution to obtain 4-iodobenzoyl hydrazide. This process requires controlling the reaction conditions, such as temperature, reactant ratio and reaction time, to prevent overreaction or formation of impurities.
Another method uses ethyl 4-iodobenzoate as the starting material. It is first mixed with an appropriate amount of sodium hydroxide solution, heated and hydrolyzed to obtain sodium 4-iodobenzoate. After acidification, 4-iodobenzoic acid is obtained. Then follow the above method of preparing 4-iodobenzoyl hydrazide from 4-iodobenzoic acid to obtain it. Although this route has a little more steps, the raw material 4-ethyl iodobenzoate is relatively easy to obtain, and the reaction conditions of each step are relatively mild, easy to operate and control.
Another person uses 4-iodoaniline as the starting material. After diazotization, the amino group is converted into a diazo salt, and then reacted with ethyl benzoate. After a series of conversions, 4-iodobenzoyl hydrazide can also be prepared. However, the diazotization reaction requires low temperature operation, and the diazonium salt is unstable, which requires strict reaction conditions. Double attention must be paid during operation.
All synthesis methods have their own advantages and disadvantages. It is necessary to choose carefully according to the actual situation, such as the availability of raw materials, cost, reaction conditions and product purity requirements, etc., to synthesize 4-iodobenzoic hydrazide efficiently.

4-Iodobenzoyl hydrazide is also an organic compound. Its physical properties are quite critical and it is widely used in scientific research and chemical industry.
First of all, its appearance, under room temperature and pressure, 4-iodobenzoyl hydrazide is mostly white to light yellow crystalline powder. This shape is easy to observe and process, the texture of the powder is delicate, and the touch is also unique.
Times and melting point, the melting point of 4-iodobenzoyl hydrazide is usually between 195-199 ° C. The melting point is an inherent property of the substance, and this value can help identify its purity. If the purity is high, the melting point should be within this range and the melting range should be narrow; if it contains impurities, the melting point may be deviated and the melting range will be wider.
In terms of solubility, 4-iodobenzoyl hydrazide is slightly soluble in water. Water is a common solvent, and this property indicates that its solubility in water is limited, or because of the weak interaction between its molecular structure and water molecules. However, it is soluble in common organic solvents, such as ethanol, dichloromethane, etc. In ethanol, it can be well dissolved to form a uniform solution. This is due to the existence of suitable interactions between ethanol and 4-iodobenzoyl hydrazide molecules, such as hydrogen bonds, van der Waals forces, etc., which can promote the miscibility of the two.
Furthermore, the density of 4-iodobenzoyl hydrazide is about 1.82g/cm ³. Density reflects the mass per unit volume of a substance, which determines the space it occupies in different environments and the relative positional relationship when mixed with other substances.
The physical properties of 4-iodobenzoic hydrazide are interrelated and jointly affect their performance in various reactions and applications. Scientific research and chemical practitioners need to understand in detail before they can be used properly.

4-Iodobenzoyl hydrazide is also an organic compound. It has specific chemical properties and is widely used in the field of organic synthesis.
In terms of physical properties, 4-iodobenzoyl hydrazide is often white to white powder, stable at room temperature, when exposed to hot topics or open flames, or there is a risk of combustion. Its melting point is specific, about [X] ° C. This property helps to distinguish and purify.
When it comes to chemical activity, the benzene ring in its molecule is aromatic, giving the compound a stable structure. Iodine atoms are active and easily participate in nucleophilic substitution reactions. For example, under appropriate reaction conditions, iodine atoms are replaced by nucleophiles to form new organic compounds. This reaction is an important path for the construction of carbon-heteroatom bonds.
Furthermore, the hydrazide group is also a check point for reactivity. It can condensate with carbonyl compounds such as aldose and ketone to form hydrazone derivatives. This reaction condition is mild and the yield is quite high, which is often used in drug synthesis and materials science. And the hydrazide group can participate in the coordination of metal ions to form metal complexes, which has made a name for itself in catalysis and biomedical imaging.
In addition, 4-iodobenzoyl hydrazide has different solubility in organic solvents. It has good solubility in polar organic solvents such as dimethyl sulfoxide and N, N-dimethylformamide, but little solubility in non-polar solvents such as n-hexane and ether. This difference in solubility is of great significance in the separation, purification and choice of reaction medium of compounds.
In short, 4-iodobenzoyl hydrazide has diverse chemical properties due to its unique chemical structure, which is of great value in many scientific fields.

4 - iodobenzohydrazide is also a chemical substance. The price in the market varies depending on the number of reasons. Among them, it is difficult to determine the price range, whether it involves changes in supply and demand, or the difficulty of controlling production, or is related to the quality.
If you seek a rough number, in today's city, if the quality is ordinary, the price per gram may be between a few yuan and a few tens of yuan. If its quality is fine and pure, the price of pure products that reach high standards should be more expensive, or more than a hundred yuan per gram, or even hundreds of yuan.
However, these are all speculative numbers, and the actual price often changes due to market movements and business policies. To determine the price, you can visit various chemical merchants or explore online chemical trading platforms to inquire about their details.