4 Iodobenzonitrile

4-Iodobenzonitrile, Chinese name 4-iodobenzonitrile, is a key intermediate in the field of organic synthesis and has a wide range of uses in many fields.
In the field of pharmaceutical synthesis, its role is crucial. Due to the structure of aromatic nitrile and the properties of iodine atoms, it can participate in a variety of reactions to construct molecular structures with specific biological activities. For example, by coupling with other compounds containing active groups, drugs for specific diseases can be prepared. For example, in the development of anti-tumor drugs, 4-iodobenzonitrile can be used as a key starting material to generate substances with inhibitory activity against tumor cells through a series of chemical reactions.
In the field of materials science, it also plays an important role. By virtue of its own structural characteristics, it can participate in the synthesis of polymer materials. After appropriate reaction, it is introduced into the main chain or side chain of the polymer to give the material special properties. Such as improving the optical properties, electrical properties or thermal stability of the material. In the field of organic optoelectronic materials, the use of new materials synthesized by 4-iodobenzonitrile may improve the luminous efficiency and stability of the device.
In pesticide chemistry, 4-iodobenzonitrile is also an important synthetic block. Compounds with insecticidal, bactericidal or herbicidal activities can be constructed through chemical reactions. Due to its unique structure, synthetic pesticides may have high efficiency, low toxicity and environmentally friendly characteristics, providing assistance for the sustainable development of modern agriculture. In conclusion, 4-iodobenzonitrile is an indispensable compound in many fields such as medicine, materials, and pesticides due to its unique chemical structure, which is of great significance for promoting technological progress and innovation in various fields.

4-Iodobenzonitrile is an organic compound whose physical properties are worth exploring. The appearance of this substance is often white to light yellow crystalline powder, which is quite characteristic. When it comes to the melting point, it is between 118 and 121 ° C. In this temperature range, the state of the substance will change, from solid to liquid. The boiling point is roughly around 300.8 ° C. When the temperature rises to this point, the substance will transform from liquid to gaseous.
Solubility is also one of its important physical properties. 4-Iodobenzonitrile exhibits good solubility in organic solvents, such as common chloroform, dichloromethane, ethanol, etc., which can be mixed with it. However, in water, its solubility is very small, which is mainly due to the molecular structure characteristics and the weak interaction between water molecules.
In addition, the density of the compound is about 1.88 g/cm ³, reflecting the mass of the substance per unit volume. Its vapor pressure is relatively low, indicating that at room temperature, the tendency of volatilization from solid or liquid to gaseous state is small.
The physical properties of 4-iodobenzonitrile, such as appearance, melting point, boiling point, solubility, density and vapor pressure, have a profound impact on its application in organic synthesis, medicinal chemistry and other fields. According to its physical properties, researchers can reasonably choose reaction conditions, separation and purification methods.

The synthesis method of 4-iodobenzonitrile, although the ancient book "Tiangong Kaizhi" does not detail the synthesis method of this specific compound, can be deduced from the ancient chemical process ideas.
In the past, halides were often reacted with corresponding aromatic hydrocarbons with halogenating agents. To obtain 4-iodobenzonitrile, benzonitrile can be taken as the substrate and iodide as the iodine source. In ancient times, potassium iodide was used as the iodine source, but it can also be used today. Choose a suitable catalyst, such as a copper-based catalyst, and copper salts are often the choice of catalysis in organic synthesis in the past, whereby iodine atoms and benzonitrile can be promoted. When
reacts, the reaction temperature and time need to be controlled. In the ancient process, temperature control is related to the effectiveness of the reaction. The reaction may be at a moderate temperature, such as tens of degrees Celsius to 100 degrees Celsius, to ensure a smooth and efficient reaction. The time also needs to be adjusted. If it is too short, the reaction will not be complete, and if it is too long, it will cause side reactions.
can also be prepared by cyanylation of 4-halobenzene. Take 4-halobenzene first, such as 4-chlorobenzene or 4-bromobenzene, and use a cyanide reagent. In the past, potassium cyanide was used to replace the halogen atom with a cyanide group. However, potassium cyanide is highly toxic, so be careful when using it. In operation, 4-iodobenzonitrile can be obtained by mixing appropriate proportion of reactants in a suitable solvent, catalyzing it, and controlling temperature in a timely manner.
In general, using ancient chemical ideas and operations, select substrates, iodine sources, cyanide reagents, and control temperature, time, and ratio to achieve the purpose of synthesizing 4-iodobenzonitrile.

4-Iodobenzonitrile is an important raw material for organic synthesis. During storage and transportation, many matters need to be paid attention to.
When storing, the first environment. It should be placed in a cool, dry and well-ventilated place. This is because it is afraid of moisture and heat. If it is placed in a high temperature and humid place, it is easy to deteriorate and affect its chemical properties and purity. The temperature should be controlled within a specific range, generally not exceeding [X] ° C, and the humidity should not be higher than [X]%.
Furthermore, the packaging must be tight. Use a container with good sealing performance to prevent contact with air and moisture. For sealed bottles and cans made of commonly used glass or plastic materials, it is necessary to consider their compatibility with 4-iodobenzonitrile to avoid chemical reactions.
When transporting, safety comes first. Due to the risk of certain hazards, the handling process must be handled with care, and must not be violently vibrated or hit to prevent package damage. Transportation vehicles must also be dry, ventilated, and kept away from fire and heat sources to prevent the risk of fire or explosion.
At the same time, transportation and storage should follow relevant regulations and standards, and be equipped with necessary protective measures and emergency equipment. In case of emergencies such as leaks, personnel should be quickly evacuated to a safe area and properly disposed of according to the established emergency plan to ensure the safety of personnel and the environment from pollution.

4-Iodobenzonitrile is also an organic compound. The market price often varies depending on the purity of the product, supply and demand, and the place where it is produced.
Looking at the market, the price may hover between a few yuan and tens of yuan per gram. If it is of ordinary purity, the price may be lower; if it is of high purity, it is especially suitable for precision research and specialty industries, and the price is higher.
In the past, due to sufficient supply and lack of demand, the price became stable and low. However, chemical and pharmaceutical research and development are on the rise, and their demand is gradually increasing, causing the price to rise. The lack of production, or the price change of raw materials, can also lead to the price of 4-iodobenzonitrile.
At some time, due to the new high-efficiency method of the first producer, the output increased greatly, and the price fell. Later, he used this product to increase, seeking excess supply, and the price rose again. Therefore, its market price often ranges from a few yuan per gram to tens of yuan per gram, and it is difficult to determine the exact number, all due to the variety of market conditions.