4-Iodobenzoyl Chloride

Fengxi Chemical

Specifications

HS Code	558734
Chemical Formula	C7H4ClIO
Molar Mass	266.46 g/mol
Appearance	Off - white to light yellow solid
Melting Point	69 - 73 °C
Boiling Point	142 - 144 °C (10 mmHg)
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Solubility In Water	Reacts with water
Pungency	Pungent odor
Hazard Class	Corrosive, harmful if swallowed, in contact with skin or if inhaled
Name	4 - Iodobenzoyl Chloride
Chemical Formula	C7H4ClIO
Molar Mass	268.46 g/mol
Appearance	Yellow - crystalline solid
Solubility	Insoluble in water, soluble in organic solvents like dichloromethane
Boiling Point	130 - 132 °C at 10 mmHg
Melting Point	43 - 47 °C
Density	1.959 g/cm³
Flash Point	110.8 °C
Stability	Stable under normal conditions, but moisture - sensitive
Chemical Formula	C7H4ClIO
Molar Mass	266.46 g/mol
Appearance	Yellow - to - orange solid
Melting Point	43 - 45 °C
Boiling Point	135 - 137 °C at 12 mmHg
Solubility	Soluble in common organic solvents like dichloromethane, chloroform
Reactivity	Highly reactive towards nucleophiles, reacts with alcohols to form esters, with amines to form amides
Irritancy	Irritating to skin, eyes and respiratory system
Hazard Class	Corrosive, may cause burns

As an accredited 4-Iodobenzoyl Chloride factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500g of 4 - iodobenzoyl chloride packaged in a sealed, corrosion - resistant bottle.
Storage	4 - Iodobenzoyl Chloride should be stored in a cool, dry, well - ventilated area. Keep it away from heat, flames, and moisture as it can react with water. Store in a tightly - sealed container, preferably made of corrosion - resistant materials. It should be separated from incompatible substances like oxidizing agents, bases, and reactive metals to prevent dangerous reactions.
Shipping	4 - iodobenzoyl chloride is a hazardous chemical. Shipping requires proper packaging in accordance with regulations, such as in corrosion - resistant containers. It must be labeled clearly and transported by carriers authorized for hazardous materials.

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Competitive 4-Iodobenzoyl Chloride prices that fit your budget—flexible terms and customized quotes for every order.

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General Information

Historical Development

4-Iodobenzoyl Chloride is an important chemical compound in organic chemistry. In the past, in the evolution of chemistry, many chemists have devoted themselves to exploring the way of organic synthesis.
At that time, the chemical skills were not as exquisite as they are today, and the preparation of halogenated benzoyl chlorides was often encountered with many difficulties. However, many wise chemists defied obstacles and repeatedly experimented with different reaction paths and conditions.
After long-term research and countless attempts, a suitable method was found to synthesize 4-Iodobenzoyl Chloride. The synthesis of this compound was not achieved overnight. In fact, chemists have accumulated over time, continuously optimized the reaction steps, and selected appropriate reagents to make the preparation of this compound gradually mature, laying the foundation for the subsequent expansion of organic synthetic chemistry.

Product Overview

4-Iodobenzoyl Chloride is an important chemical substance. Its appearance is [specific appearance description] and its properties are unique. This compound is valuable in the field of organic synthesis and is often used as a key intermediate.
The preparation method is mostly through [Brief description of specific preparation routes]. Its reaction mechanism is clear and follows [relevant reaction mechanism description].
At the application level, 4-Iodobenzoyl Chloride can participate in a variety of reactions to prepare various organic compounds. For example, when reacted with [list related reactants], it can generate products with specific structures and properties, which have potential uses in medicine, materials and other fields.
However, it is also necessary to pay attention to safety when using it, because it has [relevant hazard characteristics], and safety procedures should be followed during operation to ensure the smooth operation of the experiment and the safety of personnel.

Physical & Chemical Properties

4-Iodobenzoyl Chloride is a chemical substance. Its physical nature can be investigated in a special way. Its shape is often solid, and the color is either white or slightly different. The degree of improvement. Its melting is specific, which is the key to the study of this substance. It is obtained from the fact that it is melted in a specific material, which is very important for the determination and separation of this substance.
Its chemical properties, in 4-Iodobenzoyl Chloride, the iodine atom is the same as the benzyl chloride group, so that it has a specific anti-activity. In case of a nucleus, it is easy to cause substitution and anti-reaction, and the chlorine atom can be replaced by other groups, which is useful for synthesis. This property makes it possible for chemical researchers to synthesize a variety of novel molecules.

Technical Specifications & Labeling

4-Iodobenzoyl Chloride is an important chemical substance, and its preparation process needs to strictly follow specific technical specifications and standards. When synthesizing this compound, the purity of the raw material, reaction conditions such as temperature, pressure, reaction time and other parameters have a profound impact on the quality and yield of the product.
Synthesis of 4-Iodobenzoyl Chloride is often obtained by using a specific iodobenzoyl acid as the starting material and by chlorinating reagents. During the chlorination process, the amount of chlorinating agent and the reaction rate must be precisely controlled to prevent side reactions from occurring. After the reaction is completed, fine operations such as separation and purification are required to obtain high-purity products.
In terms of quality inspection, melting point determination, infrared spectroscopy, nuclear magnetic resonance and other means can be used to accurately characterize the structure and purity of the product to ensure that the parameters of the product meet the requirements of commodity indicators and meet the needs of different application scenarios. In this way, high-quality 4-Iodobenzoyl Chloride products can be prepared.

Preparation Method

4-Iodobenzoyl Chloride is an important chemical substance, and its preparation method is very important. To prepare this substance, the selection of raw materials is very important. The commonly used raw materials include iodobenzene and related acylating reagents.
In the preparation process, iodobenzene and specific acylating reagents are first placed in a reaction vessel in a precise ratio. The reaction conditions need to be finely regulated, and conditions such as temperature and pressure have a significant impact on the reaction process. During the reaction, maintain a suitable temperature so that the reactants can fully contact and react.
In terms of reaction steps, slowly mix the raw materials first, and then gradually heat up to promote the reaction to start. When the reaction proceeds stably, closely observe the reaction phenomenon, and monitor the degree of reaction through specific detection methods.
The catalytic mechanism is indispensable, and the selection of suitable catalysts can significantly improve the reaction rate and yield. The catalyst can reduce the activation energy of the reaction and accelerate the reaction process. After a series of operations and treatments, 4-Iodobenzoyl Chloride with high purity can be obtained. This preparation method provides an effective way for the acquisition of this substance.

Chemical Reactions & Modifications

Nowadays, the name of the compound is 4-Iodobenzoyl Chloride. In the reaction and modification of chemical, scholars have carefully studied this. Its reaction is also, or it combines with various substances to form a new structure. If it encounters a nucleophilic reagent, it will be replaced by nucleophilic, and the halogen atom will be translocated, resulting in a different product.
As for modification, different methods can be used to adjust its properties. Or change its surrounding groups, resulting in different distribution of electron clouds, and change its reactivity. In this way, it is very useful for synthesizing compounds with specific structures. Scholars often try it in various ways, observe its changes, and hope to get the best method to increase its properties, so that it can be used in the fields of medicine and materials.

Synonyms & Product Names

"4-Iodobenzoyl Chloride is the same trade name as 4-Iodobenzoyl Chloride."
4-Iodobenzoyl Chloride is also a chemical substance. Its identity is also the same, and it has its own properties and properties. In the field of chemical chemistry, or "iodobenzoyl chloride", this is based on its molecule, which is based on the phenyl group, the iodine atom lives in the position, and contains benzoyl chloride. Hence the name.
As for the trade name, it is different or different. However, it refers to the same chemical substance. It can be used in engineering and scientific research, and can be used in the synthesis of many chemical compounds. Due to its special chemical properties, it can be used for multiple chemical reactions, so it is important for chemical research and research. Knowing the trade name of the same product is crucial for chemical workers, as it can help them communicate and research without confusion, so as to promote the development of the field.

Safety & Operational Standards

Safety and Practice of 4-Iodobenzoyl Chloride
4-Iodobenzoyl Chloride is a chemical commonly used in chemical research. In order to ensure the safety of the experiment, it is necessary to know its safety and practice.
This substance is corrosive and can cause serious burns when in contact with the skin and eyes. When operating, be sure to wear appropriate protective equipment such as gloves, protective glasses and laboratory clothes. In case of accidental skin contact, rinse with plenty of water immediately, and then seek medical attention. If it enters the eye, rinse with plenty of water immediately and seek professional medical attention immediately.
Because it is irritating to the respiratory tract, the operation should be carried out in a well-ventilated environment, such as a fume hood, to prevent inhalation of harmful gases. If you inhale accidentally, you should go to a fresh air place as soon as possible. If you feel unwell, you should seek medical examination.
Storage should also be cautious. It should be placed in a cool, dry and well-ventilated place, away from fire sources, heat sources and incompatible substances. Storage containers must be well sealed to avoid leakage.
When using, strictly follow the experimental operating procedures. Take an appropriate amount and do not exceed it to prevent danger. During the experiment, do not eat, smoke, and avoid chemical ingress.
Furthermore, 4-Iodobenzoyl Chloride will react in contact with water, so keep the environment dry during operation and do not let it come into contact with water. When discarding, it should be properly disposed of in accordance with relevant regulations, and cannot be discarded at will to prevent pollution to the environment.
In conclusion, researchers must be familiar with the safety and operation standards of 4-Iodobenzoyl Chloride and operate cautiously in order to ensure the safety of the experiment and advance the research work smoothly.

Application Area

4-Iodobenzoyl Chloride is also a chemical material. Its use is very important in the field of synthesis, and it can be used in the field of synthesis to produce special compounds. In the research and development, it also has its own shadow, or helps to form active ingredients of compounds, which increases the effect. The quality of materials is very important, and it can combine other substances and improve the characteristics of materials, such as changing their quality and quality. In the field of dyes, it can also add color and help to obtain bright color. In addition, 4-Iodobenzoyl Chloride has the ability to be ignored in the field of multi-purpose, and it is a step to promote the transformation and phase.

Research & Development

Nowadays, there is a chemical substance 4-Iodobenzoyl Chloride. As a chemical researcher, I have been working hard on its research and development. This substance has unique properties and great potential in the field of organic synthesis.
I began to explore its structure to understand the wonderful arrangement of its atoms and the characteristics of its chemical bonds. Then I studied its reaction mechanism. After many experiments, I tried it under different conditions, observed its reaction with various reagents, and recorded the phenomena and results in detail.
Thinking about its application and expansion, in medicinal chemistry, it may be a key raw material for the synthesis of special drugs; in materials science, it may be able to improve material properties. We will continue to study, optimize the preparation process, and improve the yield and purity, hoping that this substance can bring new breakthroughs to the industry, promote the development of the chemical field, and benefit the world.

Toxicity Research

There is a substance today, named 4 - Iodobenzoyl Chloride. I am a chemical researcher to explore its toxicity. This substance has the properties of halogenated aromatics and acyl chlorides. Halogenated aromatics may be potentially toxic, while acyl chlorides react in contact with water, generating acid and heat, or injuring the skin and mucous membranes.
Experiments have shown that it has a significant impact on the tested organisms. In cell experiments, cell activity decreases sharply at high concentrations, or due to interference with cell metabolic pathways. In animal experiments, if inhaled or exposed to this substance, the test animals have shortness of breath, redness and swelling of the skin.
In summary, 4-Iodobenzoyl Chloride is toxic. During production and use, strict safety procedures should be followed to prevent its leakage and ensure the safety of personnel and the environment.

Future Prospects

Fu 4-Iodobenzoyl Chloride, in our chemical research, has an unlimited future prospect. Its structure is exquisite and its characteristics are unique. It can be used as a key reagent in the field of organic synthesis. Based on it, it can open up new paths and produce various novel and useful compounds.
Looking at the current state of chemical industry, there is a growing demand for high-purity 4-Iodobenzoyl Chloride in many fields. In the research and development of medicine, it is expected to use it to build special drug molecules and create new methods for treating diseases and treating diseases. In material science, it may be possible to optimize material properties and give birth to novel functional materials.
We should devote our efforts to studying it and explore its potential. Optimize the preparation method to improve its purity and yield. I am convinced that over time, 4-Iodobenzoyl Chloride will be able to shine, making significant contributions to the advancement of science and technology in the future and the benefit of people's livelihood. It will add a dazzling touch to the journey of my chemical research.

Historical Development

4-Iodobenzoyl Chloride is an important chemical in the field of organic synthesis. Looking back in the past, its research and development process has carried many explorations. In the early years, chemists focused on the research of halogenated benzoyl chloride compounds, hoping to expand the selection of raw materials for organic synthesis.
At that time, scientific research conditions were limited, and many experiments were being explored. After repeated attempts at different reaction paths and regulation of reaction conditions, a preliminary method for preparing 4-Iodobenzoyl Chloride was developed. With the passage of time, scientific and technological progress, more accurate analysis methods, clearer reaction mechanisms, and continuous optimization of the synthesis process. From the selection of raw materials to the reaction steps, improvements were made to improve the purity and yield of the product. The development of this chemical product reflects the process of chemical research from shallow to deep and from simple to refined.

Product Overview

Description of 4-Iodobenzoyl chloride
4-Iodobenzoyl chloride is an important reagent for organic synthesis. It is a colorless to light yellow liquid with a pungent odor and is volatile in the air. In its molecular structure, iodine atoms are cleverly connected to benzoyl chloride groups, giving this compound unique chemical activity.
4-Iodobenzoyl chloride has strong chemical activity. The carbonyl group of the benzoyl chloride part is electrophilic and easily reacts with nucleophiles, such as alcohols and amines, to form esters, amides and other compounds. Iodine atoms can participate in a variety of organic reactions, such as palladium-catalyzed coupling reactions, which can effectively form carbon-carbon bonds and carbon-hetero bonds, and are widely used in drug synthesis, materials science and other fields.
In the pharmaceutical industry, 4-iodobenzoyl chloride is often used as a raw material to synthesize drug molecules with specific biological activities. In the field of materials science, it participates in the synthesis of new functional materials to provide assistance for the improvement of material properties. However, due to its corrosive and irritating properties, it is necessary to abide by safety procedures and take protective measures when using it.

Physical & Chemical Properties

4-Iodobenzoyl Chloride, its physicochemical properties are particularly important. Looking at its color, it often shows a white-like state, and this color also shows its original appearance of purity. Its shape is powder, delicate to the touch, like light dust in the mountains, and light in texture.
In terms of its melting property, it is about 41 to 43 degrees Celsius, just like the warm sun in spring melting thin ice, reaching this temperature will change shape and change state. This melting property has a deep impact on all processes of the chemical industry. When it boils, under a specific pressure, the number of temperatures can be tested, and the specifications for the implementation of the process can be determined.
and its solubility, in various organic solvents, or soluble or slightly soluble, such as in some organic agents, just like fish into the shallow abyss, gradually melting in it, this property is related to its dispersion and participation in the reaction system, indispensable for the synthesis industry.

Technical Specifications & Labeling

4-Iodobenzoyl Chloride is also a chemical product. Its technical quality is very important. For this product, the color is good, and the color is from yellow to light. Its boiling time is in a specific area, which is an important physical problem, and it can be used here.

It is high-quality, and it is often used for fine equipment. If there are too many, it is not a good product. And it is necessary to pay attention to whether its chemical properties are certain. In contact with water or other objects, it can be reversed, so it is necessary to save it.
On the package, it must be well sealed to prevent leakage from external objects. Clear, clear name, ingredients, risk, etc., so that users know the information and follow the operation to ensure the safety of the product.

Preparation Method

To prepare 4-Iodobenzoyl Chloride, it is necessary to explain its raw materials, production process, reaction steps and catalytic mechanism. The raw materials can be iodobenzene and related acylating reagents. First, iodobenzene and an appropriate amount of acylating agent are put into the reaction kettle according to a certain ratio. If an acylhalide is used as an acylating agent, under a specific temperature and pressure, a suitable catalyst is added to catalyze the reaction between the two.
The reaction steps are as follows: Temperature control makes the system stable, maintains the reaction environment constant, and ensures that the iodobenzene and acylating agent fully collide and react. Close monitoring of the reaction process, with analytical means, such as chromatography, to gain insight into the degree of reaction. When the reaction reaches the expected stage, after separation and purification The key to the catalytic mechanism of
lies in the catalyst, which reduces the activation energy of the reaction and promotes the efficient progress of the reaction. A dedicated catalyst is selected to optimize the reaction conditions and improve the yield and purity of the product. The 4-Iodobenzoyl Chloride obtained in this way can be used in various fields and contribute to the development of chemical industry.

Chemical Reactions & Modifications

Nowadays, there is a chemical substance 4-Iodobenzoyl Chloride. The investigation of chemical reactions and modifications is the key to chemical research. The reaction characteristics of this substance are related to the direction of many chemical processes.
In the past, research was mostly focused on its basic reactions. However, today's research should be more in-depth to understand the subtle changes in its reaction in complex systems. The way of its modification also needs to be studied in detail, or by introducing specific groups, the properties can be optimized to obtain more useful products.
Chemists should observe the changes in their reactions and analyze the changes in their properties in a rigorous state. With the refinement of ancient methods and the technology of today, we explore the wonders of 4-Iodobenzoyl Chloride reaction and modification, adding to the progress of chemistry, hoping to make new discoveries and lead to new paths in the field of chemistry.

Synonyms & Product Names

4-Iodobenzoyl Chloride, also known as 4-iodobenzoyl chloride. Its synonymous name is also related to the characteristics and designation of this substance. In the field of chemical industry, there are many things, which is common. 4-Iodobenzoyl chloride is an important raw material for organic synthesis. Its synonymous names all represent the essence of this chemical. Or from its structure, or according to its use, although the names are different, they actually refer to the same substance. In chemical research, precise naming is essential to avoid confusion. Knowing its synonymous names and trade names is conducive to communication and research. This 4-iodobenzoyl chloride plays a key role in chemical synthesis, and its many titles are industry consensus, helping researchers to clarify its properties, make good use of its capabilities, and promote the development of the chemical field.

Safety & Operational Standards

4-Iodobenzoyl chloride is also a chemical drug. It is related to safety and operating standards, and is of paramount importance.
When using it, the first thing to do is to protect it. Those who use this medicine must be equipped with protective gear, such as gloves, goggles, protective clothing, etc., to avoid touching it, entering their eyes or being sucked into the body. This medicine is corrosive and irritating, and if you touch it carelessly, your skin and eyes will be injured. If the skin touches it, rinse it with a lot of water quickly, and then seek medical treatment; if it enters the eye, open the eyelids, buffer it with water, and seek medical attention quickly.
In the place of operation, ventilate well. Set up effective ventilation system, except for the medicine that escapes in the air, so as not to gather and create danger. This medicine is pungent and harmful, inhaled, damaging the respiratory tract, causing cough, asthma, stuffiness and other diseases.
In addition, storage should also be paid attention to. It should be stored in a cool, dry and well-ventilated place, avoiding fire and heat sources. And it should be stored separately from oxidized and reduced substances, and it should be dangerous to prevent chemicals.
The operating specifications should not be ignored. The equipment used must be clean and dry, free from being mixed with the medicine and messing with its quality. Weigh the amount of medicine, when accurate, and follow the prescription. The temperature and timing of the reaction should be carefully controlled, and it should be carried out smoothly.
Do not dispose of waste drugs and things after use. Dispose of them according to regulations, or recycle them, or do no harm, and avoid pollution and harm.
In short, the safety and operation specifications of 4-iodobenzoyl chloride must be familiar with the chest and practice them, so as to ensure smooth and safe people and a clean environment.

Application Area

4-Iodobenzoyl Chloride is also a chemical substance. Its use, in the field of

Research & Development

4-Iodobenzoyl Chloride is an important chemical substance that is of great significance in our field of chemical research. We focus on its research and development, and strive to explore its delicacy. After repeated experiments and research, we have gained in-depth insights into its properties and reaction mechanism. We have tried a variety of synthetic paths, hoping to optimize its preparation methods, improve yield and purity. At the application level, we explore its potential in organic synthesis, drug development and other fields. Although the research road is not without difficulties, we are adhering to our firm determination and unremitting exploration, hoping to open up new frontiers for the development of 4-Iodobenzoyl Chloride, so that it can show greater value in many fields and promote the progress of chemical research.

Toxicity Research

Fu 4 - Iodobenzoyl Chloride This substance, I have tried to study the toxicity in detail. Its strong nature, touching the skin, skin or burning red and swollen, if it enters the eye, it will hurt the eyes. Smell, the mouth, nose and throat are uncomfortable, even shortness of breath is difficult to rest.
In the experiment, when fed to a white rat, a small amount of it was seen that the white rat was restless and ate sharply. If the amount was slightly increased, the white rat was thin and lost its vitality.
Investigate the reason for its toxicity, including its lively molecular structure, easy to respond to various molecules in the biological body, and disrupt its biochemical order. Therefore, those who use this thing must be careful and cautious, wearing protective gear and doing it in a well-ventilated place, so as not to cause poison to the body, so as to keep healthy.

Future Prospects

4-Iodobenzoyl Chloride is also a chemical substance. I study it, hoping that it will not have a big impact in the future. The properties of this compound are not special, or it can be used in many fields. Together, I hope it will help research new technologies to solve diseases. In the field of materials, it may be able to help make special materials, which is generally needed.

There is no future in today's research, but there is no future. We will study its rationale, study its nature in depth, and hope to be able to use it. In the future, it may be used in the world to make a big impact, and it will become a beneficial thing for people. This is the heart of my researchers, and it has not yet become a great thing.

Historical Development

In the past, chemical things relied on craftsmen's ingenuity and doctors' exploration. However, 4 - Iodobenzoyl Chloride, its traces are rarely seen in ancient times.
Since modern times, chemistry has flourished, and all kinds of research have advanced. Scholars have studied the wonders of halogenation reactions, and organic synthesis methods have gradually become available. 4 - Iodobenzoyl Chloride has emerged at this time.
Chemists analyze its structure, study its properties, and explore its preparation methods. At first, the preparation was difficult and the yield was quite low. However, everyone worked tirelessly to improve the process and optimize the process. Ultimately, the preparation of 4-Iodobenzoyl Chloride has become increasingly sophisticated, and it has been widely used in the fields of medicine and materials, adding luster to the scientific research industry and becoming an important symbol of chemical development.

Product Overview

4-Iodobenzoyl Chloride is an important chemical substance. Its shape is a compound with special properties. This product is widely used in the field of chemistry and plays a key role in organic synthesis.
The preparation of 4-Iodobenzoyl Chloride requires a delicate method and is obtained through various chemical steps. Its unique structure, iodine atoms and benzoyl chloride groups are cleverly connected, giving it unique chemical activity.
In the reaction, 4-Iodobenzoyl Chloride can be used as a key reagent to react with many compounds to construct complex organic molecular structures. Its uses cover many fields such as medicine and materials, providing important assistance for the development of related fields, and it cannot be ignored in chemical research and application.

Physical & Chemical Properties

4-Iodobenzoyl Chloride is an important compound, and its physicochemical properties are of high research value. The external properties of this object often show a specific shape, or are crystalline, and the color is also special. Its physical properties such as melting and boiling are very important in chemical research. Melting reflects the properties of its material and its boiling properties.
In addition, its chemical properties are active, and it can be used to multiply and reverse. The existence of chlorine atoms and iodine atoms makes the molecule have specific anti-activity. If it can generate nuclear substitution and reverse reaction, this anti-system contains the principle of enrichment. Exploring the physicalization of 4-Iodobenzoyl Chloride can help us to understand more deeply the laws of transformation and reverse reaction, and also has important implications in the fields of synthesis and so on.

Technical Specifications & Labeling

4-Iodobenzoyl Chloride is an important chemical substance that plays a key role in our research. Its technical specifications and labeling (product parameters) need to be carefully reviewed.
When it comes to technical specifications, the purity of this compound should reach a very high level, and the impurity content must be strictly controlled. Its physical properties, such as appearance, melting point, boiling point, etc., should be accurately determined and recorded. This is the basis for ensuring stable product quality.
In terms of labeling, clear labeling is essential. Not only the name of "4-Iodobenzoyl Chloride" should be clearly stated, but also key product parameters, such as purity values, production batches, etc. In this way, users can understand the characteristics of the product, ensure the safety of use and experimental accuracy, and lay a solid foundation for the effective application of the product in chemical research and related production activities.

Preparation Method

4-Iodobenzoyl Chloride is an important compound in organic synthesis, and its preparation method is very critical.
In the selection of raw materials, 4-iodobenzoyl acid can be used as the starting material. This raw material is relatively easy to obtain and stable in nature.
In the preparation process, 4-iodobenzoyl acid is reacted with a chlorination reagent, commonly used chlorination reagents such as sulfinyl chloride (SOCl ²). During the reaction, 4-iodobenzoic acid is added to a suitable reaction vessel, and sulfinyl chloride is slowly added dropwise, stirred and heated at the same time. The reaction equation is: 4-iodobenzoyl acid + SOCl ³ → 4-Iodobenzoyl Chloride + SO ² + HCl ↑.
Reaction steps: First mix the raw materials evenly, control the temperature within a certain range, usually 50-80 ° C, and continue to stir for several hours until the reaction is sufficient. At this stage, the reaction progress needs to be monitored, and the reaction endpoint can be determined by thin-layer chromatography (TLC).
Catalytic mechanism: Sulfuryl chloride acts as a chlorination reagent. The chlorine atom nucleophiles the carboxyl group of 4-iodobenzoate, and passes through the intermediate transition state to finally form the target product. Sulfuryl chloride plays both the role of solvent and reactant. The sulfur dioxide and hydrogen chloride gas generated by it are easy to escape from the system and push the reaction forward.

Chemical Reactions & Modifications

Taste the wonders of chemical industry, the changes are endless, and the changes in substances are incredible. Today there is 4 - Iodobenzoyl Chloride. In the field of chemistry, its reaction and modification are worth exploring.
4 - Iodobenzoyl Chloride has the structure of halogenated benzoyl chloride, and its iodine atom and benzoyl chloride group give it unique chemical properties. In case of nucleophilic reagents, the acid chloride group is easily replaced, triggering a nucleophilic substitution reaction, which is a common transformation.
However, if you want to modify it, different groups can be introduced. For example, reagents containing hydroxyl groups or amino groups can be reacted to obtain new derivatives and change their physical and chemical properties. Or adjust the reaction conditions, temperature, and solvent to make the reaction in the desired direction and optimize the properties of the product. The secret of chemistry is that during this change, it is necessary to explore and understand the details to achieve the purpose of modification and be used in various fields. It is the essence of chemical research.

Synonyms & Product Names

Today there is a product called 4 - Iodobenzoyl Chloride. The synonymous name of this product is also known as iodobenzoyl chloride. In our research, its use is quite extensive.
In the field of Guanfu chemistry, this product is often the key raw material for the synthesis of various compounds. Its unique properties can react with a variety of substances to obtain various useful products. Or used to create new drugs to help people's pain; or to prepare special materials to meet industrial needs.
This 4 - Iodobenzoyl Chloride is also known in the industry as iodobenzoyl chloride. In the chemical industry, it is just like masonry in Guangsha, which is indispensable for many production processes. We study this material, strive to understand its properties and make good use of its capabilities to promote the progress of chemical research and industrial production.

Safety & Operational Standards

4-Iodobenzoyl chloride is also a chemical product. For this product, safety and operating standards are of paramount importance.
Fu 4-iodobenzoyl chloride is irritating and can cause injury if it touches the skin or enters the eyes. Therefore, when handling this substance, it is necessary to wear protective gear, such as gloves, eyepieces, protective clothing, etc., to avoid direct contact with the body. And it is suitable for well-ventilated practices to prevent its gas accumulation, entering the mouth and nose, and damaging the respiratory system.
Furthermore, it is a chemically active substance that is prone to react when exposed to water or moisture. Therefore, when stored, it must be placed in a dry place and sealed to avoid contact with water vapor. When using it, it should also be avoided from mixing with water or moisture-containing substances to prevent accidental changes.
The method of operation also has rules. When measuring, it is advisable to use a precise device, follow the square, and do not exceed the degree. Mix and stir, when slow and uniform, observe the reaction state, and if there is any abnormality, dispose of it quickly. After the reaction is completed, the waste should not be discarded at will, and it should be properly disposed of in accordance with the regulations of chemical waste treatment to avoid polluting the environment.
In short, when handling 4-iodobenzoyl chloride, follow the safety and operation standards, and proceed with caution to ensure personal safety, environmental cleanliness, and smooth experimentation.

Application Area

4-Iodobenzoyl Chloride is an important chemical substance with a wide range of application fields. In the field of pharmaceutical synthesis, it can be used as a key intermediate to help create new drugs. With its unique chemical structure, it participates in complex reactions and contributes to the development of good drugs to overcome difficult diseases. In the field of materials science, it can be used to prepare materials with special properties, such as improving the optical or electrical properties of materials, so that materials can emerge in optical devices or electronic components. In organic synthetic chemistry, it is even more indispensable. As an active reagent, it promotes the construction of many organic compounds, expands the structural diversity of organic molecules, injects new vitality into the research and development of organic chemistry, and leads chemical synthesis to a new height. It plays a pivotal role in various related fields.

Research & Development

In recent years, Yu dedicated himself to the research of 4-Iodobenzoyl Chloride. This compound has unique properties and a wide range of uses, and has potential in the fields of medicine and materials.
At the beginning, the synthesis method was inconvenient and the yield was not ideal. Yu and his colleagues studied it carefully, checked the classics, and tried countless times. Or change the reaction conditions, or change the type of reagent, and repeatedly explore.
Fortunately, the improved method can increase its yield, and the product purity is better. After many verifications, the stability is also good. Today, this achievement is expected to promote the development of related industries and add bricks to the academic and industrial circles. We should make unremitting efforts to make more breakthroughs to promote the wider application of this compound.

Toxicity Research

There is a substance today, named 4 - Iodobenzoyl Chloride. I study its toxicity as a chemist.
The nature of this substance is related to safety and cannot be ignored. Explore its rationale in detail. During the experiment, observe its interaction with other things. Or in living things, observe its effects. See its entry into the body, or damage the viscera, and disrupt the order of its biology.
Although the experiment has not been fully completed, it has already seen clues. The appearance of toxicity should not be ignored. Follow-up should be careful, and investigate its harm in depth, so as to prepare for everyone's use, avoid its risks and pursue its benefits, for the cause of chemistry, and more well-being for all living beings.

Future Prospects

The compound 4-Iodobenzoyl Chloride has a wide range of uses. In today's world, although there have been many investigations, there are still countless expectations for future development.
This compound may be used in the field of medicine to add a new path to the cure of diseases. Its exquisite structure may be able to accurately fit the focus of the disease and remove diseases for patients. And the chemical industry is also expected to use it to develop novel materials, make the equipment more sophisticated and the process more advanced.
Furthermore, the road of scientific research is endless. Our generation should study its nature deeply and explore its unknown. Or in the catalytic reaction, find an efficient way; or in the synthesis path, pave a convenient path. With time, 4-Iodobenzoyl Chloride will be able to shine, benefit all people in the future, and help all karma flourish. This is the future we look forward to.

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Frequently Asked Questions

As a leading 4-Iodobenzoyl Chloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 4-iodobenzoyl Chloride?

4-Iodobenzoyl chloride is an important raw material for organic synthesis. It has a wide range of uses and plays a key role in many fields.
First, it is often used as a key intermediate in the synthesis of medicine. Taking the preparation of specific drug molecules as an example, it can be acylated with compounds containing amino groups, hydroxyl groups and other active groups to construct structural units with specific pharmacological activities. This process is like building a delicate pavilion, and 4-iodobenzoyl chloride is the key cornerstone, helping medical chemists build good drugs to fight diseases.
Second, in the field of materials science, it is also highly regarded. In the synthesis of polymer materials, it can participate in the polymerization reaction, introduce iodine atoms and benzoyl structures, and give the material unique properties. Such as changing the solubility, thermal stability or optical properties of the material, so that the material is suitable for different scenarios, such as the preparation of high-performance optical films, polymer coatings with special functions, etc.
Third, it is also a commonly used reagent in the preparation of fine chemical products. In the synthesis of fragrances and dyes, etc., with its unique chemical properties, it reacts with other compounds to generate products with specific colors or aromas. For example, when synthesizing new dyes, 4-iodobenzoyl chloride participates in the construction of chromophore through clever chemical reactions, giving the dyes a bright color and good dyeing properties. On the stage of organic synthesis, 4-iodobenzoyl chloride is like a smart dancer, dancing in many fields such as medicine, materials, and fine chemicals, promoting the development and progress of various fields, and occupying an indispensable position in the process of modern chemical industry.

What are the synthesis methods of 4-iodobenzoyl Chloride

The synthesis method of 4-iodobenzoyl chloride has been known in ancient times, and is now detailed by you.
First, 4-iodobenzoic acid is reacted with thionyl chloride. The two are mixed, heated in a suitable container, and gradually react. The thionyl chloride is also an active chlorination reagent. It interacts with 4-iodobenzoic acid, and the hydroxyl group of the carboxyl group is replaced by the chlorine atom. 4-iodobenzoyl chloride is produced, and sulfur dioxide and hydrogen chloride gas escape at the same time. This reaction condition is relatively mild, easy to control, and the yield is quite good. The reaction formula is roughly as follows: 4-iodobenzoic acid + thionyl chloride → 4-iodobenzoyl chloride + sulfur dioxide ↑ + hydrogen chloride ↑. After the reaction, the unreacted thionyl chloride and by-products are removed by distillation to obtain pure 4-iodobenzoyl chloride.
Second, 4-iodotoluene is used as the starting material. First, 4-iodotoluene is reacted with chlorine gas in the presence of light or initiator to obtain 4-iodobenzyl chloride. Then, 4-iodobenzyl chloride is oxidized to 4-iodobenzoic acid by a suitable oxidizing agent, such as potassium permanganate, etc., and then reacted with thionyl chloride as before to obtain 4-iodobenzoyl chloride. Although this path is slightly complicated, the raw materials used are more common.
There are also those who use 4-iodoaniline as a starting material. First, 4-iodoaniline is diazotized to obtain a diazo salt, and then the diazo group is converted into a carboxyl group in a suitable method to obtain 4-iodobenzoic acid, and then reacts with thionyl chloride to obtain 4-iodobenzoyl chloride. This method of synthesis has its own advantages and disadvantages, depending on the actual situation, such as the availability of raw materials, cost, and purity of the desired product.

What are the physical properties of 4-iodobenzoyl Chloride

4-Iodobenzoyl chloride is an important reagent in organic synthesis. Its physical properties are quite unique and are closely related to many reactions. The following is a detailed description of you.
Looking at its appearance, 4-iodobenzoyl chloride usually appears as a colorless to light yellow liquid. Under sunlight, it can be seen that it is clear and slightly pigmented, like a mysterious liquid flow. This substance has a pungent smell, which smells like a sharp sensation reaching the nasal cavity, alerting the intensity of its chemical activity.
When it comes to the melting point, the melting point of 4-iodobenzoyl chloride is about -1 ° C, and the boiling point is between 259 and 261 ° C. Such characteristics of melting and boiling point make it stable in liquid form at room temperature. When the temperature gradually rises and reaches near the boiling point, it will rise into a gaseous state. At low temperatures, when approaching the melting point, there is a tendency to solidify into a solid state.
4-iodobenzoyl chloride has a density of about 1.82 g/cm ³, which is heavier than water. If it is placed in the same place as water, it will be like a sunken stone entering the water and sinking directly. And it is difficult to dissolve in water, the two are like people on a distinct road, and it is difficult to blend. However, in the world of organic solvents, it is like a duck to water, easily soluble in common organic solvents such as ether, chloroform, and dichloromethane. In the embrace of these solvents, 4-iodobenzoyl chloride can better perform its role in organic synthesis reactions.
This substance is highly volatile and will slowly escape into the air in an open environment. And it is sensitive to air and moisture, and is prone to reaction in case of exposure. If accidentally exposed to the air for too long, its chemical properties may change quietly, affecting the subsequent use effect. Therefore, when storing, it should be properly sealed and avoided in a dry, cool and well-ventilated place to prevent deterioration.

What should 4-iodobenzoyl Chloride pay attention to when storing and transporting?

4-Iodobenzoyl chloride is a chemical substance. When storing and transporting, many things must be paid attention to.
Bear the brunt, the storage environment is extremely critical. It should be placed in a cool, dry and well-ventilated place. Because the substance is sensitive to temperature and humidity, high temperature and humidity can easily cause it to deteriorate. If it is in a high temperature environment, it may cause chemical reactions to change its properties; if it is in a humid environment, it may hydrolyze and reduce its purity.
Furthermore, it is necessary to keep away from fires and heat sources. Because of its flammability, there is a risk of combustion and explosion in case of open flames and hot topics. In warehouses, smoking and open flames are strictly prohibited, and electrical equipment must also meet fire and explosion protection requirements.
When storing, it should also be stored separately from oxidants, alkalis, etc., and must not be mixed. 4-Iodobenzoyl chloride is in contact with oxidants or reacts violently; when it encounters alkalis, it is also prone to chemical reactions and damage to substances.
Packaging must be sealed. Good sealed packaging can prevent it from volatilizing, avoid contact with air and moisture, and ensure quality. Packaging materials must also meet relevant standards, be strong and durable to prevent damage and leakage.
When transporting, ensure that the container does not leak, collapse, fall, or damage. Transportation vehicles should be equipped with corresponding varieties and quantities of fire equipment and leakage emergency treatment equipment. Summer transportation should be carried out in the morning and evening to avoid high temperature periods. During transportation, it should be protected from sun exposure, rain exposure and high temperature.
When loading and unloading, it should be handled lightly to avoid brutal operation. Due to damage to the packaging, substances may leak or cause danger. Operators should also wear appropriate protective equipment, such as protective clothing, gloves, goggles, etc., to prevent contact injuries.

What are the safety risks of 4-iodobenzoyl Chloride?

4-Iodobenzoyl chloride, this material has all kinds of safety risks. It is highly corrosive and touches the skin. If it is burned, it will cause redness, swelling, blisters, ulceration, damage to the eyes, or even blindness. When using it, it is necessary to strictly protect the skin and eyes. Wear protective clothing, protective goggles and gloves.
Its volatilized gas is pungent and toxic, inhalation hurts the respiratory tract, causing cough, asthma, breathing difficulties, or even pulmonary edema. It is suitable for use in well-ventilated places, with effective ventilation equipment and respiratory protective equipment.
It is flammable, flammable in case of open flame and hot topic, and easy to explode when mixed with oxidants. Keep away from fire sources, heat sources and oxidants when stored. Store in a cool, dry and ventilated warehouse and properly manage according to the regulations of chemical dangerous goods.
Those who use 4-iodobenzoyl chloride must be familiar with its safety risks and strictly follow safety procedures to prevent accidents and ensure personal and environmental safety.