4 Iodobenzylamine

4-Iodobenzylamine, this is also an organic compound. Its physical properties, at room temperature, are mostly in a solid state, but they also vary depending on the specific environmental conditions. Looking at its appearance, it may be a white to off-white powder with a certain melting point, slightly in a certain temperature range. This temperature varies slightly due to specific purity and other factors.
When it comes to chemical properties, its amine group is quite active. The nitrogen atom in the amine group contains lone pairs of electrons, which makes it easy to react with acids to generate corresponding salts. For example, in the case of hydrochloric acid, hydrochloric acid can be formed. This reaction is like the combination of yin and yang. After forming a salt, the solubility and other properties of the compound also change.
Furthermore, the presence of benzyl moiety endows it with certain aromatic hydrocarbon properties. The substitution of iodine atoms makes the compound active in some chemical reactions. Iodine atoms can participate in nucleophilic substitution reactions. Due to their large atomic radius and relatively low C-I bond energy, iodine atoms are easily replaced by other nucleophilic reagents under suitable reaction conditions. For example, with the help of alkaline environment and specific catalysts, it can be substituted with nucleophilic reagents containing hydroxyl groups and mercapto groups, and then a series of new compounds can be derived.
In addition, 4-iodobenzylamine is widely used in the field of organic synthesis. It can be used as an important intermediate to build more complex organic molecular structures through various chemical reaction pathways, providing key starting materials for the synthesis of drugs, materials, and other fields, just like the building blocks of high-rise buildings.

4-Iodobenzyl amine is also an important compound in the field of organic synthesis. The common synthesis methods are as follows.
First, 4-iodobenzoic acid is used as the starting material. First, 4-iodobenzoic acid is co-heated with dichlorosulfoxide to obtain 4-iodobenzoyl chloride. In this step, dichlorosulfoxide is used as a chlorination agent to convert the carboxyl group into an acyl chloride group. The reaction is violent, and attention should be paid to temperature control. Then, 4-iodobenzoyl chloride is reacted with excess ammonia and goes through an amidation process to generate 4-iodobenzoamide. This reaction is relatively mild, and at a suitable temperature and reaction time, a product with high yield can be obtained. Finally, using lithium aluminum hydride as a reducing agent, 4-iodobenzamide is reduced in an organic solvent such as anhydrous ether to obtain 4-iodobenzyl amine. Lithium aluminum hydride has extremely strong reduction ability, and care should be taken during operation to avoid contact with active hydrogen substances such as water.
Second, 4-iodobenzyl bromide is used as the starting material. The 4-iodobenzyl bromide is reacted with the potassium salt of phthalimide in a suitable solvent. This is a nucleophilic substitution reaction, and the bromine atom is replaced by the phthalimide group to generate 4-iodobenzyl phthalimide. After that, the hydrazolysis reaction is carried out with hydrazine hydrate and other reagents, and the phthalimide group is converted into an amino group, and finally 4-iodobenzylamine is obtained. This route step is relatively simple, and the reaction conditions of each step are easy to control.
Third, 4-iodotoluene is used as the starting material. First, 4-iodotoluene is reacted with N-bromosuccinimide (NBS) in the presence of light or initiator, and bromine atoms are introduced at the methyl to obtain 4-iodobenzyl bromide. This reaction requires attention to the light intensity or the amount of initiator to control the reaction selectivity. Subsequently, 4-iodobenzyl bromide is reacted with ammonia or aminating reagent to form 4-iodobenzylamine by nucleophilic substitution. During this process, the amount of ammonia or aminating reagent and the reaction conditions have a great influence on the yield and purity of the product.

4-Iodobenzylamine is also an organic compound. It is useful in many fields such as pharmaceutical research and development, materials science, etc.
In the context of pharmaceutical research and development, this compound is often a key building block for the synthesis of novel drug molecules. Due to the properties of iodine atoms and benzylamine groups in its structure, it can endow the synthesized drugs with unique physical, chemical and biological activities. For example, it may be used to construct anti-cancer drugs with specific targeting properties. Iodine atoms can improve the lipid solubility of drug molecules, helping them to more easily penetrate cell membranes and reach tumor cell targets; benzylamine groups can interact with specific parts of biological macromolecules, such as binding to certain receptors or enzymes, and then exert anti-cancer effects. In addition, in the development of antimicrobial drugs, 4-iodobenzylamine may also have potential. By modifying its structure, it can synthesize drugs that have inhibitory effects on specific bacteria.
As for the field of materials science, this compound also shows potential value. In the creation of organic optoelectronic materials, 4-iodobenzylamine can participate in the construction of molecular systems with special optoelectronic properties. The heavy atom effect of iodine atoms may affect the electron cloud distribution of molecules and change the optical properties of materials, such as fluorescence emission wavelength and quantum yield; benzylamine groups can provide active checking points for covalent connection with other materials or formation of supramolecular assemblies, thereby regulating the microstructure and macroscopic properties of materials. For example, introducing it into a conjugated polymer system may improve the charge transport performance of polymers, providing a boost for the performance of organic Light Emitting Diodes (OLEDs), organic solar cells and other devices.
In summary, 4-iodobenzylamine has emerged in the field of medicine and materials science with its unique structure, contributing to the development of related fields and opening up many new possibilities.

4-Iodobenzylamine is also an organic compound. Its market price often varies due to changes in quality, purity, suppliers and market supply and demand. In the era of "Tiangong Kaiwu", this compound was not known to the world, but today, the chemical industry is prosperous and the market is numerous.
If the approximate price is discussed, the pure product of 4-iodobenzylamine is in the chemical reagent market. In terms of common packaging specifications, the price per gram of higher purity may be around tens of yuan to hundreds of yuan. This is because the preparation of this compound requires a specific chemical reaction, and the cost of raw materials and the difficulty of the synthesis process all affect its selling price.
If you purchase in large quantities, such as kilograms, the price per gram may be reduced to a lower range due to the scale effect, but it also depends on the specific situation of the market. Those with more impurities and less purity should be cheaper. However, the specific price needs to be consulted in detail with each chemical reagent supplier to obtain a more accurate figure.

4 - iodobenzylamine is an organic compound, and its storage conditions are crucial, which is related to the stability and safety of the substance. The storage should be based on the following conditions:
First, it needs to be placed in a cool and well-ventilated place. This compound is prone to reaction when heated, and the temperature is too high or causes decomposition and deterioration. A cool environment can reduce its molecular active level and keep its chemical properties stable. Good ventilation is also essential to avoid the accumulation of volatile gases, reduce the risk of explosion and poisoning.
Second, keep away from fire and heat sources. 4 - iodobenzylamine is flammable. In case of open flame, hot topic or ignition, fireworks are strictly prohibited in the storage area, and heat sources should also be kept at a safe distance from it, such as heating, steam pipes, etc., which should not be approached.
Third, it should be stored separately from oxidants and acids, and mixed storage should not be avoided. 4 - iodobenzylamine is chemically active. It comes into contact with oxidants or has a violent oxidation reaction. Mixing with acids or causing chemical reactions can cause hazards such as explosion and toxic gases.
Fourth, the storage container must be well sealed. This compound is easy to react with oxygen, moisture, etc. in the air. A sealed container can prevent it from coming into contact with the air, prevent oxidation, hydrolysis and other reactions, and ensure its quality. In general, it is recommended to use glass bottles or plastic bottles. If a large amount of storage is used, metal drums can be used, but it is necessary to ensure that the material does not react with it.
Fifth, the storage place should be equipped with suitable equipment for containing and handling leaks. In case of leakage, it can be collected and treated in time to reduce environmental pollution and personal injury. Such as adsorption materials, neutralizers, etc. are all necessary.
In short, 4-iodobenzylamine storage needs to be careful and strictly follow the above conditions to ensure its quality and storage safety, and prevent accidents.