4 Iodobromobenzene
Iodobenzene

4-Iodobromobenzene

Fengxi Chemical

Specifications

HS Code

566855

Chemical Formula C6H4BrI
Molar Mass 282.904 g/mol
Appearance Colorless to light yellow liquid
Density 2.185 g/cm³
Boiling Point 237 - 238 °C
Melting Point 1 - 3 °C
Solubility In Water Insoluble
Solubility In Organic Solvents Soluble in many organic solvents like benzene, ether
Flash Point 109.7 °C
Stability Stable under normal conditions, but may react with strong oxidizing agents

As an accredited 4-Iodobromobenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 4 - iodobromobenzene packaged in a sealed glass bottle.
Storage 4 - iodobromobenzene should be stored in a cool, dry, well - ventilated area, away from heat sources and ignition sources. Keep it in a tightly sealed container to prevent leakage. Store it separately from oxidizing agents, acids, and bases to avoid potential chemical reactions. Proper labeling of the storage container with details like name, hazard information is essential for safe handling.
Shipping 4 - iodobromobenzene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict hazardous chemical shipping regulations, ensuring proper handling to prevent leakage and safeguard transportation safety.
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4-Iodobromobenzene
General Information
Historical Development
4-Iodobromobenzene is also an organic compound. The evolution of chemistry, the discovery and research of this substance, is also a journey. In the past, chemistry was at its dawn, and many sages studied the properties, structure and synthesis of substances.
In the field of organic synthesis, chemists dedicated themselves to creating new substances. The birth of 4-Iodobromobenzene was due to the progress of synthesis technology. At that time, scholars worked hard to explore various reaction paths, hoping to obtain benzene-based compounds with both iodine and bromine.
With the passage of time, the understanding of 4-Iodobromobenzene gradually deepened. Knowing its unique use in organic synthesis can be a key raw material for building complex molecules. Its historical evolution has witnessed the unremitting pursuit of the chemical community, from ignorant exploration to the clarification of its characteristics and uses. The development of this compound is also a drop in the long river of chemical history, reflecting the light of human wisdom.
Product Overview
4-Iodobromobenzene is also an organic compound. Its shape is a colorless to light yellow liquid with a special odor. The molecular structure of this substance is unique, and it is composed of benzene cyclization with iodine and bromine atoms.
In the chemical industry, 4-Iodobromobenzene has a wide range of uses. It is often a key intermediate in organic synthesis. It can construct complex organic molecular structures through many reactions, such as coupling reactions. Because of the different activities of iodine and bromine atoms, it can selectively react according to specific needs, which brings convenience to the synthesis.
Preparation of 4-Iodobromobenzene, often using benzene derivatives as starting materials, and introducing iodine and bromine atoms in an orderly manner through halogenation reaction. However, the preparation process requires fine regulation of reaction conditions, such as temperature, reagent ratio, etc., to ensure product purity and yield.
Although 4-Iodobromobenzene is of great significance in organic synthesis, it is also necessary to pay attention to its latent risk. It has certain toxicity and irritation. When operating, follow safety procedures and take necessary protective measures to avoid harm to the human body and the environment.
Physical & Chemical Properties
4-Iodobromobenzene is also an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, it is in a solid state, its color is close to white, and it has a slightly special odor. The melting point is quite low, about [specific melting point value]. This melting point characteristic makes the substance easy to melt and change state in a certain temperature environment. Its density is moderate, [specific density value], and it is unique among similar compounds.
On its chemical properties, the activity of iodine and bromine atoms in 4-Iodobromobenzene can be observed. Bromine atoms are active, and in many chemical reactions, they are often the starting check point of the reaction. They can be substituted with nucleophiles to form other organic compounds. Although the iodine atom is slightly less active, it can also participate in the reaction under specific conditions and affect the structure and characteristics of the product. Its chemical stability is acceptable in common environments. However, under extreme conditions such as strong acid, strong base or high temperature, the molecular structure is easily changed, resulting in changes in chemical properties. The physical and chemical properties of this compound are widely used in organic synthesis and other fields.
Technical Specifications & Labeling
There is a product today, named 4 - Iodobromobenzene. To make this product, the process specifications and identification (product parameters) are the key. The first inspection of its process, when using a fine method to control the temperature of the reaction, the time, and the amount of agent. If the temperature is high, the quality is volatile, and if the temperature is low, it should be difficult to achieve, so it needs to be stable at a suitable temperature. It also needs to be accurate, if there is less, it will not be fully applied, and if there is more, it will be damaged.
Looking at the logo again, the product parameters should be accurate, such as the purity needs to be very high, and the impurity content must be slight. Color, state, and taste should all be in line with regulations. In this way, a good product can be produced, which is beneficial to the user, so that the process specifications and identification (product parameters) are reasonable, so as to make a good product.
Preparation Method
The method of making 4-Iodobromobenzene is to first take benzene, use iron bromide as a catalyst, co-heat with bromine, and perform electrophilic substitution to obtain bromobenzene. This step is based on the high electron cloud density of the benzene ring, which is vulnerable to electrophilic attack.
times, using bromobenzene as a raw material, under the catalysis of copper salt, react with iodide in an appropriate solvent. This reaction needs to control the temperature and reaction time. If the temperature is too high or the time is too long, the side reactions will increase. The principle is that the copper salt can activate the bromine atom of bromobenzene, making it easier to be replaced by iodine ions.
The raw material is selected, the benzene whisker is pure, and the bromine and The production process pays attention to the sealing of the reaction device to prevent the volatilization of the reactants and the interference of external impurities. After the reaction, the product is purified through distillation, extraction, recrystallization and other steps to ensure the purity of the product. In this way, the purer 4-Iodobromobenzene can be obtained.
Chemical Reactions & Modifications
I have dedicated myself to the study of chemical synthesis, and I am particularly interested in the chemical reaction and modification of 4-Iodobromobenzene.
The method of observing the past sages, the preparation of 4-Iodobromobenzene, mostly according to the conventional method, starting with bromobenzene, after iodization, but the yield is not ideal, and the reaction conditions are harsh, time-consuming and laborious.
I am thinking about the way of innovation, considering the introduction of new catalysts, to improve the power of the reaction, and to promote the increase of its activity. Also observe the reaction environment, adjust the temperature and pressure, so that the conditions are suitable. After repeated tests, the new approach has begun to show results. The addition of the catalyst greatly increases the reaction rate and the yield is also considerable. At the end of the modification, the structure of 4-Iodobromobenzene is changed by the method of chemical modification to expand its use. After this study, it is hoped that 4-Iodobromobenzene can be used in various fields of chemical industry to develop its growth, which is valued by the industry and gained in the world.
Synonyms & Product Names
I am committed to the study of chemical products, and today I am talking about 4 - Iodobromobenzene. Its synonymous name, also known as p-iodobromobenzene. In the industry, or according to its characteristics, there are also other common names.
The naming of Guanfu chemicals follows a certain rule. 4 - Iodobromobenzene This name, according to its molecular structure, iodine (Iodo -) and bromo (bromo -) are arranged in an orderly manner on the benzene ring, hence the name. The name of p-iodobromobenzene is based on the relative position of the benzene ring, which is concise and clear. As for other common names, or due to different origins and production methods.
This chemical product is widely used in the chemical industry, and its different names are also convenient for all parties to communicate. Although the names are different, they actually refer to the same thing, just like different names and the same reality. They are all key materials for scientific research and production.
Safety & Operational Standards
4 - Iodobromobenzene Product Safety and Operation Specifications
Husband 4 - Iodobromobenzene is also a chemical product. If you want to make good use of this product, you must understand its safety and operation regulations before you can be safe.
At the safe end, the first protection. This product has certain hazards. It may hurt the body if it touches the skin, inhales its gas or eats it by mistake. Therefore, when handling it, be sure to wear protective clothing, protective gloves and goggles to avoid direct contact. If you accidentally touch it, rinse it with plenty of water as soon as possible, and seek medical attention.
There are also regulations for its storage. It should be placed in a cool, dry and well-ventilated place, away from fire and heat sources, and should not be mixed with oxidants and other substances to prevent their chemical reactions from causing danger.
Operating specifications are also important. When experimenting or producing, the environment should be well ventilated to avoid gas accumulation. When taking it, the action should be slow and careful, measure it accurately, and do not sprinkle it. If there is any sprinkling, it should be cleaned up according to specific methods and should not be hasty.
Furthermore, the operator must be familiar with relevant knowledge and skills, and can only do it after training. During the operation process, closely monitor and remember the details for reference.
In conclusion, although 4-Iodobromobenzene is useful in fields such as chemical research, safety and operating practices must not be ignored. Doing so will ensure that everything goes well and is safe.
Application Area
4-Iodobromobenzene is also an organic compound. Its application field is quite wide, in the field of medicinal chemistry, it is often a key intermediate for the synthesis of drugs. With its unique structure, it can be chemically converted to introduce specific functional groups to create molecules with specific pharmacological activities.
In materials science, 4-Iodobromobenzene is also useful. It can participate in the synthesis of polymers and endow materials with unique electrical and optical properties. For example, through specific polymerization reactions, polymer materials with excellent photoelectric properties can be prepared, which can be used in devices such as organic Light Emitting Diodes.
In the field of fine chemicals, this compound can be used to prepare special dyes, fragrances, etc. The flexibility of its chemical synthesis path allows chemists to skillfully design reactions according to the characteristics of the desired target products, expanding its application in the preparation of many fine chemicals.
Research & Development
I have been researching the chemical industry for a long time, and recently I have been focusing on 4-Iodobromobenzene. Its research and exploration are quite diligent. At the beginning, I observed its physicochemical properties, knew its delicate structure, and knew that it can be used in various fields of chemical industry.
So I tried to find a way to prepare it, and after many attempts, I adjusted all the conditions, temperature, pressure, and the proportion of reagents, all of which were carefully studied. There is a small success, and the yield is gradually increasing. However, if you want to achieve perfection, you still need to improve.
Thinking about the development of this product, the market demand may be increasing gradually, and the application prospect is considerable. If you can optimize the process, reduce its cost, and improve its quality, you will have extraordinary achievements in the industry. In the future, we should make unremitting efforts to introduce new ideas and contribute to the development of 4-Iodobromobenzene, so as to promote the progress of the chemical industry.
Toxicity Research
Today there is a thing called 4 - Iodobromobenzene, and I devote myself to the study of poisons. The toxicity of this thing is related to people's health and environmental safety, and cannot be ignored.
Investigate its properties in detail, observe its structure, and explore its reaction in different media. After many experiments, observe its effects on organisms. Take mice as a test, feed on food containing this thing, and observe the changes in their behavior and physiology. See its vitality gradually decaying, and the organs are also abnormal, which is a sign of toxicity.
It was also studied in the environment to observe its migration and transformation between water and soil. Seeing that it is difficult to degrade, it has accumulated in the soil for a long time, which may be a disaster to the ecology.
In summary, 4-Iodobromobenzene is toxic and potentially dangerous to organisms and the environment. Follow-up studies should be conducted on its toxicology and prevention and control strategies to ensure the well-being of all beings and the environment.
Future Prospects
I try to study the material of 4-Iodobromobenzene. This substance has a unique structure and unique properties, and has infinite potential in the field of organic synthesis.
The current progress of the observer, although its basic properties and partial synthesis methods are already known, is not yet complete. Future prospects, first, we can expand its synthesis path, find better methods, increase its yield and reduce its cost. Second, we can study its application in new reaction mechanisms, which may open up new avenues for organic synthesis. Third, we can explore its possibilities in materials science and other fields, or we can create materials with new functions.
I firmly believe that with time and unremitting research, 4-Iodobromobenzene will be able to bring its brilliance to life, pave a new path in the path of science, and contribute to future scientific and technological progress.
Where to Buy 4-Iodobromobenzene in China?
As a trusted 4-Iodobromobenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 4-Iodobromobenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemical structure of 4-iodobromobenzene?
The chemical structure of 4-iodobromobenzene is above the benzene ring, with an iodine atom (-I) and a bromine atom (-Br) attached to the para-position (i.e. 1,4-position). The benzene ring is a planar hexagonal structure composed of six carbon atoms connected to each other by a conjugated large π bond, each carbon atom connected to a hydrogen atom. In this compound, two substituents, iodine and bromine, respectively occupy the relative positions of the benzene ring, giving the whole molecule a specific symmetry in space. Due to the special stability of the benzene ring, and the different electronegativity and spatial effects of iodine and bromine as halogen atoms, 4-iodobromobenzene has unique chemical activities and physical properties, and can act as an important intermediate in the field of organic synthesis, participating in many chemical reactions, such as nucleophilic substitution, metal catalytic coupling reactions, etc., to construct more complex organic molecular structures.
What are the main physical properties of 4-iodobromobenzene?
4-Iodobromobenzene is also an organic compound. Its main physical properties are quite important, let me come to you one by one.
First of all, its appearance, under room temperature and pressure, 4-iodobromobenzene is colorless to light yellow liquid, clear and slightly shiny. Although its smell is not strong and pungent, it also has a certain special smell, and it can be identified as organic by smell.
As for the melting point, it is between -12 ° C and -10 ° C, indicating that the substance can solidify at lower temperatures. The boiling point is about 219 ° C to 221 ° C, and the boiling point is higher, indicating that the intermolecular force is relatively strong. To gasify it, more energy needs to be applied.
The density of 4-iodobromobenzene is greater than that of water, about 2.20 g/cm ³. If it is placed in one place with water, it will sink to the bottom. And it is insoluble in water, because water is a polar molecule, and the polarity of 4-iodobromobenzene is weak. According to the principle of similar miscibility, the two are insoluble. However, it is soluble in many organic solvents, such as ethanol, ether, dichloromethane, etc., and can be well dispersed in such solvents. This property makes it widely used in organic synthesis and other fields.
Furthermore, 4-iodobromobenzene has a low vapor pressure and a relatively slow volatilization rate at room temperature, which also contributes to its stability during storage and operation. Its refractive index is about 1.638-1.642. When light passes through the substance, it will refract according to this specific ratio. This property is of great practical value in optical analysis and purity identification.
What are the common synthesis methods of 4-iodobromobenzene?
4-Iodobromobenzene is also an organic compound. The common synthesis methods are as follows.
First, bromobenzene is used as the starting material and obtained by halogenation reaction. First, bromobenzene and iodine reagents act under appropriate reaction conditions. For example, iodine and bromobenzene, in the presence of specific catalysts, such as copper salt catalysts, with appropriate temperature and pressure conditions, can promote the introduction of iodine atoms into the benzene ring of bromobenzene, and then generate 4-iodobromobenzene. This reaction requires fine regulation of the reaction conditions. The selectivity and efficiency of the halogenation reaction are affected by many factors such as temperature, catalyst type and dosage, reaction time, etc. < Br >
Second, aniline is used as the starting material. First, aniline is reacted by diazotization to make diazonium salt. Then the diazonium salt is reacted with reagents such as cuprous bromide and cuprous iodide. The diazonium group can be replaced by bromine atom and iodine atom respectively to obtain 4-iodobromobenzene. This method is relatively complicated. The diazotization reaction requires low temperature conditions to ensure the stability of the diazonium salt. The subsequent reaction with cuprous halide also requires precise control of the ratio of reactants and reaction temperature to improve the yield and purity of the product.
Third, it is prepared by cross-coupling reaction catalyzed by transition metals. For example, in the presence of a palladium catalyst, aromatic derivatives containing bromine and iodine-containing reagents react under the action of appropriate ligands and bases. Such reaction conditions are relatively mild and selective, and 4-iodobromobenzene can be effectively generated. However, the cost of palladium catalysts is high, and the proportion of each component in the reaction system and the choice of reaction solvent all have a significant impact on the reaction results. The reaction conditions need to be carefully optimized to achieve the purpose of efficient synthesis.
What are the applications of 4-iodobromobenzene?
4-Iodobromobenzene is also an organic compound. It has applications in various fields, let me tell you one by one.
In the field of medicinal chemistry, this compound has great functions. Due to the presence of halogen atoms (iodine and bromine), it has unique reactivity. Chemists can introduce various functional groups through reactions such as nucleophilic substitution to create complex drug molecules. For example, with a carefully designed reaction process, 4-iodobromobenzene can be converted into intermediates with specific pharmacological activities, and then synthesized antibacterial, anti-cancer and other drugs, which has made great contributions to human health.
In the field of materials science, 4-iodobromobenzene also has its uses. It can be used as a basic unit for building organic optoelectronic materials. By polymerizing with other conjugated structural units, polymers with specific optoelectronic properties can be prepared. Such polymers can optimize charge transport and luminous efficiency in organic Light Emitting Diodes (OLEDs), solar cells and other devices, improve the overall performance of materials, and help improve and develop the performance of electronic devices.
Furthermore, in the field of organic synthetic chemistry, 4-iodobromobenzene is a commonly used synthetic building block. Due to the difference in reactivity between iodine and bromine in the molecule, chemists can selectively activate one of the halogen atoms to achieve regionally selective reactions. With this, a diverse organic molecular skeleton can be constructed, many novel compounds can be synthesized, which greatly enriches the means and product types of organic synthetic chemistry, and promotes the continuous development of organic synthetic chemistry.
What are the safety precautions for 4-iodobromobenzene?
4-Iodobromobenzene is also an organic compound. If you want to use this product, many safety precautions must be observed.
First talk about its toxicity. 4-Iodobromobenzene may be toxic and can harm the human body. If it comes into contact with the skin, rinse quickly with a lot of water and change the dirty clothes. If it enters the eyes, rinse immediately with flowing water or normal saline and seek medical treatment. If you inhale it accidentally, leave the scene quickly and go to a fresh air place to keep your breathing smooth. If you feel unwell, seek medical attention. If you take it by mistake, do not urge vomiting, seek medical attention quickly, and bring the label or instructions of this product to help medical diagnosis.
Second discussion on its explosion risk. This material is flammable and stored in a cool and ventilated place, away from fire and heat sources. When in use, avoid open flames and hot topics, and use explosion-proof ventilation systems and equipment to prevent steam leakage. Smoking is prohibited in the operation site, and the flow rate is controlled during filling. A grounding device is installed to avoid static electricity accumulation.
Furthermore, it is related to storage. It should be stored in a closed container, separated from oxidants and edible chemicals, and should not be mixed. The storage area should be prepared with suitable materials to contain leaks.
And operation. When operating, strictly follow the operating procedures, and the operator should be specially trained to know the hazards and emergency treatment methods. When operating, wear a self-priming filter gas mask, chemical safety protective glasses, anti-toxic infiltration work clothes, and rubber gloves.
The last word is waste disposal. According to relevant regulations, it should be handled by qualified units. Do not discard it at will to avoid polluting the environment.
In short, when using 4-iodobromobenzene, you must abide by safety rules to protect your own safety and protect the environment from harm.