4-Iodomethoxybenzene

Fengxi Chemical

Specifications

HS Code	502229
Chemical Formula	C7H7IO
Molar Mass	220.03 g/mol
Appearance	Colorless to light yellow liquid
Boiling Point	230 - 232 °C
Density	1.812 g/cm³
Solubility In Water	Insoluble
Solubility In Organic Solvents	Soluble in common organic solvents like ethanol, ether
Vapor Pressure	Low
Stability	Stable under normal conditions

As an accredited 4-Iodomethoxybenzene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	500g of 4 - iodomethoxybenzene packaged in a sealed, chemical - resistant bottle.
Storage	4 - Iodomethoxybenzene should be stored in a cool, dry place away from direct sunlight. Keep it in a well - sealed container to prevent exposure to air and moisture, which could potentially lead to decomposition or degradation. Store it separately from incompatible substances like strong oxidizing agents. Ideal storage temperature is around 2 - 8°C if possible to maintain its stability.
Shipping	4 - Iodomethoxybenzene is shipped in well - sealed, corrosion - resistant containers. It's transported under controlled conditions, avoiding exposure to heat, moisture, and incompatible substances to ensure safe delivery.

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General Information

Historical Development

4-Iodomethoxybenzene, organic compounds are also. In the past, chemical sages explored the mysteries of matter and worked tirelessly in the field of organic synthesis. At first, to obtain this compound, the method was not good, the yield was quite low, and the impurities were numerous.
However, the heart of a scholar is as firm as a golden stone, and it has been repeatedly researched over the years. Or improve the conditions of the reaction, or explore novel reagents. After many hardships, the method of optimization is gradually obtained. The reaction environment is precisely controlled, the temperature and pressure are fixed; the raw materials used are carefully selected and of high quality.
As a result, the preparation technology of 4-Iodomethoxybenzene is improving day by day, the yield is improved, and the purity is also good. It has gradually become important in many fields such as medicine and materials, paving the way for the development of science in later generations, and making great contributions.

Product Overview

4-Iodomethoxybenzene, organic compounds are also. Its color is pure and pure, and it has unique chemical properties. This substance is based on a benzene ring, and is connected to an iodine atom and a methoxy group. The iodine atom has strong electron-absorbing properties, and the methoxy group has the energy of a electron donor. The two give the compound special reactivity.
In the field of organic synthesis, 4-Iodomethoxybenzene has a wide range of uses. It can be used as a key intermediate, involving coupling reactions and combining with many organometallic reagents to produce complex organic molecules. With the exquisite design of reaction paths, chemists can build a diverse scientific framework and lay the foundation for new drug research and development, material creation and other fields.
Its physical properties cannot be ignored either. The characteristics of melting point, boiling point and solubility all have a profound impact on its application. The level of melting point is related to its physical state transformation, and the solubility is determined by the possibility of participating in the reaction in different solvent systems. Chemists use its properties to choose appropriate reaction conditions to achieve the purpose of efficient synthesis.

Physical & Chemical Properties

4-Iodomethoxybenzene is an organic compound, and its physical and chemical properties are of great research value. The appearance of this compound may be colorless to light yellow liquid, with a specific odor. In terms of solubility, it is slightly soluble in water, but easily soluble in organic solvents, such as ethanol, ether, etc. Due to the principle of "similar phase dissolution", its organic structure is compatible with the forces between organic solvent molecules.
In terms of chemical properties, iodine atoms are highly active and can participate in many substitution reactions. Its methoxy group can affect the electron cloud density of the benzene ring, making the adjacent and para-sites of the benzene ring more prone to electrophilic substitution reactions. In addition, the stability of the compound may change under specific conditions, and factors such as heat and light may cause it to decompose or react. The investigation of the physicochemical properties of 4-Iodomethoxybenzene is of great significance in the fields of organic synthesis and drug development, and can help researchers better use this compound to achieve their desired goals.

Technical Specifications & Labeling

The technical specifications and identification (product parameters) of Jinyan 4 - Iodomethoxybenzene. This product needs to be prepared in a precise way. At the beginning of its synthesis, an appropriate amount of raw materials should be taken, and the proportion must be accurate. During the reaction process, conditions such as temperature and duration must also be strictly controlled.
As for the label, on the product packaging, the name should be "4 - Iodomethoxybenzene", and the important product parameters should be listed in detail, such as purity to a specific high standard, impurity content should be extremely low, and key physical parameters such as molecular weight, melting point, boiling point, etc. should be clearly stated, so that the user can understand its performance, use it in compliance, and ensure that the quality and safety of this product are in accordance with specifications.

Preparation Method

To prepare 4-Iodomethoxybenzene, it is necessary to prepare its raw materials first. P-methoxyphenol can be used as the starting material, and iodomethane can be used as the alkylating agent. The preparation process is as follows:
Place p-methoxyphenol in a reactor, add an appropriate amount of organic solvent, such as acetone, and stir well. Then slowly add iodomethane dropwise, and add an appropriate amount of potassium carbonate as an acid binding agent. When heated to a certain temperature and the reaction number is maintained, the reaction mechanism is that the oxygen atom of the phenolic hydroxyl group nucleophilically attacks the methyl carbon of iodomethane, and the iodine ion leaves to form 4-Iodomethoxybenzene.
After the reaction is completed, cool down, and filter to remove the solid salt. The filtrate is distilled under reduced pressure to remove the solvent. The residue was purified by column chromatography to obtain pure 4-Iodomethoxybenzene. During operation, pay attention to ventilation to avoid the toxic damage of iodomethane, and control the temperature and control to ensure the smooth reaction.

Chemical Reactions & Modifications

4 - The anti-modification of Iodomethoxybenzene is important for the study of nematurization. Its inverse process is exquisite, and multiple factors influence each other.
In normal inverse processes, the nuclear substitution of the inverse is used. With the action of the nuclear, iodine atoms can be arranged to generate new derivatives. In this process, the inverse components such as the degree and solubility are of great importance.
As for the modification, different functionalities can be introduced to change the air efficiency. For example, adding alkyl and aryl groups in a specific method can improve their physical properties. In this way, its application in materials science, chemical synthesis and other fields can be expanded, making it more efficient and promoting the first step of phase transformation.

Synonyms & Product Names

4-Iodomethoxybenzene, chemical things are also. Its synonyms and trade names are quite important in my way of chemical research. The synonyms of this substance are either named according to its chemical structure and characteristics. Or from the arrangement of its constituent elements, or according to its reaction performance, it can be the source of the name.
As for trade names, merchants choose their easy-to-remember and easy-to-know names when marketing activities to attract people. This 4-Iodomethoxybenzene has its own uses in chemical experiments and industrial production. Or as a raw material for synthesizing other things, or as an auxiliary agent for catalytic reactions.
Understanding its synonyms and trade names, our researchers can be more comfortable in the study of literature and the communication of transactions. It can avoid mistakes caused by differences in names, so that research and production can be carried out in an orderly and efficient manner. In this way, we can move forward steadily on the road of chemistry, explore more material wonders, and add luster to the academic community.

Safety & Operational Standards

4-Iodomethoxybenzene is an important chemical substance, and safety and operating standards are of paramount importance during its production and use.
All operators involved in 4-Iodomethoxybenzene need to be professionally trained and familiar with its characteristics, hazards and safe operation methods. When operating, strictly follow established procedures and do not act recklessly.
For storage, 4-Iodomethoxybenzene should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, and protected from direct sunlight. At the same time, it must be stored separately from oxidants, acids, alkalis, etc., and should not be mixed to avoid dangerous chemical reactions. The storage area should be equipped with suitable materials to contain leaks.
If a leak occurs accidentally, the first thing to do is to quickly evacuate the personnel in the contaminated area of the leak to a safe area, isolate them, and strictly limit access. Emergency personnel must wear self-contained positive pressure breathing apparatus, wear anti-toxic clothing, and do not directly contact the spill. In the event of a small leak, it can be mixed with sand, dry lime or soda ash and collected in a dry, clean and covered container. In the event of a large leak, a dike or pit should be built for containment, covered with foam to reduce vapor disasters, and then transferred to a tanker or special collector by pump for recycling or transportation to a waste disposal site.
During operation, necessary protective measures should also be taken. Operators must wear self-priming filter gas masks (half masks), wear chemical safety glasses, wear anti-poison penetration overalls, and wear rubber oil-resistant gloves to avoid contact with the skin and eyes and prevent inhalation of their vapors.
In short, for the safety and operation of 4-Iodomethoxybenzene, it is the key to ensuring the safety of personnel, environmental safety and the smooth progress of production.

Application Area

4-Iodomethoxybenzene, the application field of this substance has a lot to study. In the field of medicinal chemistry, it may be a key intermediate, which helps to create special effects and cure various diseases. From the perspective of ancient times, physicians all seek good medicines to help the common people. If this compound is well utilized, it may become a recipe for the world.
In the field of materials science, it also has potential. It can contribute to the development of new functional materials, such as improving the characteristics of optical materials, so that the optical performance of utensils is better, just like the pursuit of fine utensils and excellence in ancient times.
In the field of organic synthesis, 4-Iodomethoxybenzene is like a cornerstone, and many complex organic molecules rely on it to build, just like building a mansion, with a solid foundation to achieve great things. This is an important manifestation of its application field, which is related to people's livelihood and academics and cannot be underestimated.

Research & Development

Since modern times, the art of chemistry has become increasingly refined, and new substances have emerged one after another. Today there are 4-Iodomethoxybenzene this substance, and our chemists have studied it carefully.
At the beginning of the research, its structure was analyzed, its characteristics were known, and its unique chemical activity was known. In the reaction, it can be combined with various reagents to produce different compounds.
Explore the method of its synthesis, and after many attempts, find the best way. Or adjust the temperature, or control the pressure, or choose the appropriate catalyst to make the reaction go forward and improve the yield.
As for the field of application, the prospect is promising. In pharmaceutical chemistry, it can be used as a key intermediate to assist in the development of new drugs; in materials science, it can give materials specific properties.
Our chemists should make unremitting efforts to study this material as a foundation, expand the boundaries of chemistry, promote its development, and use it for the benefit of the world.

Toxicity Research

The study of tasting and smelling poisons is related to the health of people's livelihood, so you must not be careless. Today there is 4-Iodomethoxybenzene, and the investigation of its toxicity is quite important.
Detailed investigation of its properties, or harmful to human organs and meridians. Looking at various experiments, those who come into contact with this substance feel uncomfortable from time to time. The skin touches it, or it causes redness, swelling, and itching; inhaling its gas may disturb the lungs, causing asthma and chest tightness.
The depth of toxicity also depends on the dose and duration. A small amount of short touch, or mild symptoms can be cured; if a large dose is stained for a long time, it will cause sinking.
For today's plan, studying its toxicity requires careful investigation and clarification of the mechanism of its harm, in order to formulate a good strategy to avoid public poisoning and ensure the well-being of one party. This is the important task of those who study the toxicity of this substance.

Future Prospects

In today's view 4-Iodomethoxybenzene this thing, although it is known now, there is still a vast space for future development. In the field of medicine, it may be able to assist in the research of special effects, heal all kinds of diseases, and enable patients to regain a healthy body. In material science, it may give birth to novel materials, which are extraordinary and can be used in high-end equipment and precision equipment to improve the quality and efficiency of devices.
Our generation of scientific researchers, with enthusiasm for exploration, should make unremitting research. In the future, it is expected to precisely regulate its synthesis method, improve the yield, reduce its cost, and make this substance more ubiquitous. It is also expected to reveal more of its hidden nature, expand the field of application, contribute to the progress of the world, and paint a splendid future picture.

Where to Buy 4-Iodomethoxybenzene in China?

As a trusted 4-Iodomethoxybenzene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.

Frequently Asked Questions

As a leading 4-Iodomethoxybenzene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the chemistry of 4-iodomethoxybenzene?

4-Iodomethoxybenzene, its chemical properties are as follows:
This substance has unique reaction characteristics. Its iodine atom is active and easily participates in nucleophilic substitution reactions. When encountering nucleophilic reagents, such as alkoxides, amines, etc., iodine atoms can be replaced to form new carbon-heteroatom bonds. For example, when reacting with alkoxides, iodine leaves, and the oxygen atoms in the alkoxides are connected to the benzene ring to obtain new ether compounds. This reaction is often an important step in the construction of complex molecular structures in organic synthesis.
Its methoxy group has an effect on the distribution of electron clouds in the benzene ring. Methoxy groups are the power supply subgroups, which increase the density of electron clouds in the ortho and para-sites of the benzene ring, so the electro In case of brominating reagents, bromine is more inclined to attack ortho and para-sites to form bromogenic products.
In addition, 4-iodomethoxybenzene can participate in the addition reaction under specific conditions. Although the addition reaction conditions are harsh due to the stability of benzene ring conjugation, it can still be realized through appropriate catalysts and reaction conditions, providing a way for the introduction of other functional groups.
And because of its iodine and methoxy group, in some metal-catalyzed reactions, such as palladium-catalyzed cross-coupling reactions, it can react with substrates containing alkenyl groups and aryl halides to build carbon-carbon bonds, expand the molecular skeleton, and is widely used in drug synthesis and materials chemistry.

What are the common synthetic methods of 4-iodomethoxybenzene?

4-Iodomethoxybenzene is an important intermediate in organic synthesis. There are several common synthesis methods.
One is to use p-methoxyphenol as the starting material. First, the phenolic hydroxyl group is reacted with iodomethane through nucleophilic substitution to methoxylate the phenolic hydroxyl group to obtain 4-methoxyphenol methyl ether. Then, under suitable reaction conditions, an iodine substitution reagent, such as iodine and an appropriate oxidant, undergoes an electrophilic substitution reaction at the para-position of the benzene ring, and iodine atoms are introduced to obtain 4-iodomethoxybenzene. In this way, the raw material is easy to obtain, and the reaction step is relatively simple. However, the selectivity of the iodine substitution reaction needs to be regulated in detail to avoid the generation of side reactions. < Br >
The second can start from p-iodophenol. In an alkaline environment, 4-iodomethoxybenzene is directly generated by the nucleophilic substitution reaction between p-iodophenol and iodomethane. The alkaline environment can promote the deprotonation of phenolic hydroxyl groups, enhance their nucleophilicity, and make the reaction easy to proceed. In this method, the type and amount of alkali, the reaction temperature, and the length of time have a great impact on the yield and purity of the reaction, which must be carefully optimized.
Third, if p-bromomethoxybenzene is used as the raw material, the halogen atom exchange reaction catalyzed by metal can be used. 4-Iodomethoxybenzene is obtained by exchanging bromine and iodine atoms with iodizing reagent and p-bromomethoxybenzene under the action of palladium, copper and other metal catalysts and ligands. Metal-catalyzed reactions are often characterized by high efficiency and high selectivity. However, the cost of catalysts is higher, and the reaction conditions are also more severe. It is necessary to strictly control the anhydrous and anaerobic conditions of the reaction system.
All this synthesis method has advantages and disadvantages. In practical application, the best synthesis effect can be achieved when considering many factors such as the availability of raw materials, cost, difficulty of reaction conditions, and requirements for product purity.

4-iodomethoxybenzene in what areas

4-Iodomethoxybenzene is useful in many fields. In the field of organic synthesis, it is often used as a key intermediate. Due to the properties of iodine atoms and methoxy groups in its structure, many organic compounds can be derived through various chemical reactions, such as nucleophilic substitution and coupling reactions. For example, when building complex aromatic compound architectures, with the active reactivity of iodine atoms, nucleophilic substitution can occur with various nucleophilic reagents, and then multi-functional groups are introduced, paving the way for the creation of organic molecules with specific properties and structures.
In the field of medicinal chemistry, 4-iodomethoxybenzene also exhibits its capabilities. In the process of drug development, it is a starting material or an important intermediate, which is of great importance to the design and synthesis of drug molecules. By modifying and modifying its structure, compounds with specific biological activities can be obtained, or they can act on specific targets, providing the possibility for the creation of new drugs, and may have potential value in the treatment of diseases, such as anti-tumor and anti-infection.
Furthermore, in the field of materials science, 4-iodomethoxybenzene is also indispensable. When preparing functional materials, it can participate in polymerization reactions, etc., introducing specific functional groups into the polymer structure, giving the material special properties such as photoelectric properties and thermal stability. For example, in the preparation of organic optoelectronic materials, by ingeniously designing and incorporating the material, the charge transport performance of the material may be optimized, and the application performance of the material in optoelectronic devices such as organic Light Emitting Diodes and solar cells may be improved.

What are the physical properties of 4-iodomethoxybenzene?

4-Iodomethoxybenzene is a kind of organic compound. Its physical properties are quite many, and I will describe them in detail for you.
First of all, under normal temperature and pressure, 4-iodomethoxybenzene is often white to light yellow crystalline powder, with fine texture and pure color. This state is convenient for its use and processing in many experiments and industrial operations.
The melting point is about 38-42 degrees Celsius. The melting point is relatively low, and it is easier to transform from solid to liquid when heated. This property can be used to control the reaction process and material morphology in specific chemical reactions and material processing processes. < Br >
In terms of boiling point, it is generally between 263 and 264 degrees Celsius. A higher boiling point indicates that it can change from liquid to gaseous state at a relatively high temperature, so that it can maintain a liquid or solid state in a higher temperature environment, providing a stable basis for applications involving high temperature operation.
4-iodomethoxybenzene is insoluble in water, because water is a polar solvent, while the polarity of 4-iodomethoxybenzene molecules is relatively weak. According to the principle of "similarity and compatibility", the two are incompatible. However, it is soluble in organic solvents such as ethanol, ether, and chloroform. In ethanol, by virtue of the intermolecular force, it can be evenly dispersed to form a uniform solution system. This property provides a basis for solvent selection for its applications in organic synthesis reactions and pharmaceutical preparations.
In addition, 4-iodomethoxybenzene has a certain volatility, but the volatility is weak. Although at room temperature, the rate of its molecules escaping from the liquid surface and entering the gas phase is relatively slow, in an environment with poor ventilation and slightly higher temperature, it is still necessary to pay attention to its volatilization accumulation to avoid potential effects on the environment and operators. Its density is slightly higher than that of water. When performing operations such as liquid-liquid separation, this property is helpful to determine its distribution in the system.

What is the market price range for 4-iodomethoxybenzene?

4-Iodomethoxybenzene is 4-iodomethoxybenzene. The price of this product in the market is difficult to determine. The change in its price is related to various reasons.
First, the price of raw materials. The production of 4-iodomethoxybenzene requires specific raw materials. If the production of raw materials changes due to time, geography, and human events, the price will also change. If raw materials are difficult to find or produced less, the price of 4-iodomethoxybenzene will increase; if the raw materials are abundant, the price may stabilize and drop.
Second, the production method is easy. If the method of making 4-iodomethoxybenzene is simple and efficient, and there are many finished products, the price may be low; if the production method is difficult, time-consuming, requires a lot of materials, and the labor force is huge, the price will be high.
Third, the situation of market demand. If in the pharmaceutical, chemical and other industries, the demand for 4-iodomethoxybenzene is prosperous, but the supply is not enough, the price will rise; if the demand is light and the supply is surplus, the price will drop.
Fourth, the competition of the city. If there is a lot of business in 4-iodomethoxybenzene, the competition is fierce, and it is for the market, or there is a price reduction; if the market is controlled by a small number of businesses, the price may be determined by it, and the level may be determined at will.
From this perspective, the market price of 4-iodomethoxybenzene is difficult to determine, or a few yuan per gram, or tens of yuan, or even higher, and it must be observed according to changes in time and differences in feelings.