What is the chemical structure of 4-iodophenoxyacetic acid?
4-Iodophenoxyacetic acid is 4-iodophenoxyacetic acid, and its chemical structure is as follows.
In this compound, the core part is the benzene ring, which is like a stable "city". At position 4 of the benzene ring, there are iodine atoms, and the iodine atoms stand here like a "watchman". At position 1 of the benzene ring, it is connected to the phenoxyacetic acid group. In the phenoxyacetic acid group, the oxygen atom is connected to the benzene ring, which is like a bridge to build the connection between the two. The oxygen atom is then connected to a methylene (-CH 2O -), which is like a "bond". The methylene group is connected to the carboxyl group (-COOH), which is a rather active group, like a "genie" with unique "activity", giving the whole compound certain acidic and other chemical properties. In this way, the parts are connected to each other to build the unique chemical structure of 4-iodophenoxyacetic acid, which gives it specific physical and chemical properties and has corresponding applications in many chemical fields.
What are the main uses of 4-iodophenoxyacetic acid?
4-Iodophenoxyacetic acid, the name of the ancient or unknown, but it is widely used, in agriculture, medicine and other fields are involved.
In the field of agriculture, it is a plant growth regulator. It can help crops stabilize flowers and fruits. If it is properly applied during the flowering period, it can make flowers and fruits not easy to fall, increase the number of fruits, and then harvest. Such as the genus of tomato, if used properly, the yield of the fruit can be increased, and the fruit shape is positive, and the quality is also excellent. It can also promote the rooting of crops. The seedlings are given an appropriate amount of 4-iodophenoxyacetic acid, and the root system is rapid and strong, the soil is deeper, the plants grow healthily, and the ability to resist drought, flood and disease is also strong.
In the field of medicine, it has certain medicinal potential. After research, it has a soothing effect on some inflammation, or can be used as an anti-inflammatory adjuvant. And in the field of cancer research, some scholars have found that it has the power to inhibit the proliferation of cancer cells. Although it has not yet become a mainstream anti-cancer drug, it has opened up a new path for medical exploration.
Furthermore, in the field of laboratory research, it is an important raw material for organic synthesis. Chemists can use it to build complex organic molecules, pave the way for the creation of new compounds, the development of new materials, and the birth of many new organic materials. 4-iodophenoxyacetic acid may be involved in helping. In conclusion, 4-iodophenoxyacetic acid is used in various fields, adding luster to the world.
What are the physical properties of 4-iodophenoxyacetic acid?
4-Iodophenoxyacetic acid is a kind of organic compound. Its physical properties are as follows:
Looking at its color state, at room temperature, 4-iodophenoxyacetic acid is mostly a white crystalline solid, like fine grains, with a more delicate state.
When it comes to the melting point, its melting point is quite significant, about 154-156 ° C. At this temperature, the solid 4-iodophenoxyacetic acid gradually melts into a liquid state, which is the key node for the transformation of the state of matter. Although the exact data on its boiling point are rarely stated, it is inferred according to its structure and the properties of similar compounds. When the boiling point is in a relatively high temperature range, due to the intermolecular force, it requires more energy to overcome the binding and achieve the transition from liquid to gaseous.
In terms of solubility, 4-iodophenoxyacetic acid has little solubility in water. For water, polar solvents are also used, and the molecular structure of 4-iodophenoxyacetic acid makes it limited in polarity and weak interaction with water molecules, so it is difficult to dissolve in water. However, in organic solvents, such as ethanol, ether, acetone, etc., its solubility is relatively good. The molecules of organic solvents such as ethanol and 4-iodophenoxyacetic acid can form interactions such as van der Waals forces, which promote their molecules to be uniformly dispersed in the solvent and exhibit good solubility.
Its density is also an important physical property. Although the exact value needs to be determined by precise experiments, it can be known from its molecular composition and atomic weight that its density should be larger than that of water, that is, the mass of 4-iodophenoxyacetic acid per unit volume is greater than that of water. This property also affects its sedimentation or suspension state in different media.
In addition, 4-iodophenoxyacetic acid is stable under normal conditions. However, when exposed to high temperatures, open flames, or strong oxidants, its chemical structure may be damaged, causing chemical reactions to occur. This is also related to physical properties. For example, changes in state when heated may trigger chemical reactions.
What are the synthesis methods of 4-iodophenoxyacetic acid
The synthesis of 4-iodophenoxyacetic acid has been explored in the past. One method is to use p-iodophenol and chloroacetic acid as raw materials. First, dissolve p-iodophenol in an appropriate amount of alkaline solution, such as sodium hydroxide solution. This is because the phenolic hydroxyl group is acidic and can form a salt with the base to increase its nucleophilicity. Chloroacetic acid is also dissolved in water to form a corresponding ionic state. Mix the two and stir the reaction at an appropriate temperature, such as 60-80 ° C. This reaction is nucleophilic substitution. The phenoxy negative ion of p-iodophenol attacks the carboxyl ortho-carbon of chloroacetic acid, and the chlorine leaves to form 4-iodophenoxyacetic acid. After the reaction is completed, the pH is adjusted to acidic with acid, so that the product can be precipitated, and then the pure product can be obtained by filtration, washing, and drying.
There are also those who use p-iodophenol and hydroxyacetic acid as raw materials. In the presence of a catalyst, such as sulfuric acid or p-toluenesulfonic acid, both are heated and refluxed in an organic solvent, such as toluene. In this reaction, the carboxyl group of hydroxyacetic acid and the phenolic hydroxyl group of p-iodophenol are dehydrated and condensed to form an ester bond, resulting in 4-iodophenoxyacetic acid. After the reaction system is cooled, the product can also be obtained by extraction with a suitable solvent and purification without impurities.
In addition, p-iodoaniline is used as the starting material and is converted through a series First, p-iodoaniline is diazotized to obtain diazonium salts, and then interacts with cuprous salts, such as cuprous chloride or cuprous bromide. After the Sandmeier reaction, the diazoyl group is replaced by a halogen atom to obtain p-iodohalobenzene. Subsequent steps such as phenylation and carboxylation can obtain 4-iodophenoxyacetic acid. Although this path is a little complicated, the raw materials are easy to obtain, and it is also a useful method.
What are the precautions for 4-iodophenoxyacetic acid during use?
4-Iodophenoxyacetic acid is an organic compound. There are many things to pay attention to during use.
First, safety protection must be paid attention to. This compound may be toxic and irritating. When operating, you need to wear suitable protective equipment, such as gloves, goggles and protective clothing, to avoid skin contact and respiratory inhalation. If you accidentally come into contact with the skin or eyes, you should immediately rinse with plenty of water and seek medical attention in a timely manner.
Second, storage conditions should not be ignored. Store it in a cool, dry and well-ventilated place, away from fire sources and oxidants, to prevent fire or chemical reactions. At the same time, store it separately from other chemicals to avoid mutual contamination.
Third, the use process is rigorous and standardized. When conducting experiments or applications, it is necessary to carry out strict operation procedures and accurately control the dosage and reaction conditions. Because the reactivity of the compound may be affected by factors such as temperature and pH, it is necessary to ensure that the reaction environment is suitable.
Fourth, waste treatment also needs to be compliant. After use, the remaining 4-iodophenoxyacetic acid and related waste cannot be discarded at will, and should be properly disposed of in accordance with relevant environmental protection regulations to prevent pollution to the environment.
In conclusion, when using 4-iodophenoxyacetic acid, we must adhere to a scientific and rigorous attitude, and attach great importance to safety and environmental protection in order to ensure a smooth operation process and achieve the desired results.