4 Iodotoluene
Iodobenzene

4-Iodotoluene

Fengxi Chemical

    Specifications

    HS Code

    624466

    Chemical Formula C7H7I
    Molar Mass 218.03 g/mol
    Appearance Colorless to pale yellow liquid
    Boiling Point 211 - 212 °C
    Melting Point −31 °C
    Density 1.709 g/cm³ at 25 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in many organic solvents like ethanol, ether
    Flash Point 87 °C
    Refractive Index 1.621 (20 °C)
    Chemical Formula C7H7I
    Molecular Weight 218.03 g/mol
    Appearance Colorless to yellow - brown liquid
    Odor Characteristic aromatic odor
    Density 1.73 g/cm³ at 25 °C
    Boiling Point 211 - 213 °C
    Melting Point -36 °C
    Solubility In Water Insoluble
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
    Flash Point 85 °C
    Vapor Pressure Low vapor pressure at room temperature

    As an accredited 4-Iodotoluene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

    Packing & Storage
    Packing 500g of 4 - iodotoluene packaged in a sealed, chemical - resistant glass bottle.
    Storage 4 - Iodotoluene should be stored in a cool, well - ventilated area, away from heat sources and open flames as it is flammable. Keep it in a tightly sealed container to prevent vapor leakage. Store it separately from oxidizing agents and incompatible substances. Avoid long - term exposure to light, which could potentially cause decomposition.
    Shipping 4 - Iodotoluene is shipped in well - sealed containers, compliant with chemical transport regulations. It's often packed in corrosion - resistant materials, safeguarded against physical damage during transit to prevent spills and ensure safety.
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    4-Iodotoluene
    General Information
    Historical Development
    4-Iodotoluene is also an organic compound. In the past, chemists studied organic synthesis and dedicated themselves to the creation of new substances. At the beginning, it was difficult and complicated to obtain this 4-Iodotoluene. At that time, the technology and materials relied on were limited.
    With the passage of time, chemical technology has improved day by day. Researchers think hard and improve the synthesis method. From simple reaction raw materials, through exquisite step-by-step design, 4-Iodotoluene can be prepared more efficiently.
    Looking at its development, from the initial ignorance and exploration to the gradual maturity of the method, every step is the wisdom and sweat of chemists. Its application has also become increasingly widespread, emerging in the fields of medicine and materials, contributing to the improvement of human life, which is an important symbol in the development of chemistry.
    Product Overview
    4-Iodotoluene is an important compound in the field of organic chemistry. Its appearance is colorless to light yellow liquid, with a special odor. This compound has a wide range of uses in organic synthesis and is often the key raw material for the preparation of many complex organic molecules.
    In terms of its structure, the benzene ring is connected with methyl and iodine atoms, which gives it special chemical properties. Its chemical activity is derived from the ease of iodine atoms to leave and the electronic effect of benzene ring and methyl.
    In organic reactions, 4-Iodotoluene can be replaced by other functional groups through nucleophilic substitution reactions, thus forming new carbon-heteroatom bonds. It can also participate in metal-catalyzed coupling reactions, such as Suzuki reaction and Stille reaction, laying the foundation for the synthesis of various compounds with biological activity or material science value. Therefore, 4-Iodotoluene plays an indispensable role in the development of organic synthetic chemistry.
    Physical & Chemical Properties
    4-Iodotoluene is an organic compound. Its physical and chemical properties are particularly important to chemistry students. Looking at its shape, it can be a colorless to light yellow liquid at room temperature, with a special odor. Its boiling point is quite high, about 188-191 ° C, due to the force between molecules. And its density is greater than that of water, about 1.830g/cm ³, so it will sink at the bottom when placed in water.
    On its chemical properties, it has a unique reactivity due to the presence of benzene ring, iodine atom and methyl group. The benzene ring can undergo electrophilic substitution reactions, iodine atoms can participate in nucleophilic substitution and other reactions, and methyl affects the electron cloud density of the benzene ring, making 4-Iodotoluene exhibit special performance in many chemical reactions. It is widely used in the field of organic synthesis.
    Technical Specifications & Labeling
    4-Iodotoluene is an organic compound. The process specification for its preparation, the first heavy raw materials are carefully selected, and high-purity toluene and iodide are required. The micro-impurities are related to the quality of the product. The reaction vessel must be clean and corrosion-resistant to ensure the stability of the reaction.
    When reacting, control the temperature to a suitable degree, about XX degrees Celsius. If it is too high, the by-product will increase, and if it is too low, the rate will be slow. The stirring force should also be uniform, so that the reactants blend seamlessly.
    The label of the product indicates its name "4-iodotoluene", and its molecular formula is C H I. Standard character, room temperature is colorless to slightly yellow liquid. Column purity, when above XX%. Remember to be dangerous, flammable and irritating, store in a cool and ventilated place, away from fire heat sources. According to this process specification and marking, the quality of 4-iodotoluene can be guaranteed, and it is safe for production and application.
    Preparation Method
    The method of making 4-Iodotoluene is as follows: First take toluene as the raw material, which is commonly available. With an appropriate amount of iodine and a suitable catalyst, put it together in a special vessel. Control its temperature and pressure to make the two gradually combine.
    During the reaction, careful monitoring is required. First observe the color change of the reaction, toluene and iodine are combined at the beginning, the color may be light, and gradually turn darker. Next observe the fluctuation of its temperature, and adjust it in time to prevent excesses or slowdowns.
    After the reaction is completed, use the technique of distillation to analyze its impurities, so that 4-Iodotoluene can be purified. This method of making things requires attention to the selection of raw materials, the control of reactions, and the skills of analyzing purity, so that it can become a good product.
    Chemical Reactions & Modifications
    Nowadays, there is a chemical substance named 4-Iodotoluene. As a chemical researcher, I often study the transformation and modification of this substance.
    The chemical reaction of 4-Iodotoluene is quite important in the field of organic synthesis. Its iodine atom activity can lead to various reactions, such as nucleophilic substitution, which can meet with many nucleophilic reagents to generate new compounds, which is the basis for constructing complex organic structures. And its benzene ring has the properties of aromatic hydrocarbons, which can be used for electric substitution reactions. Add different groups to the ring to open up its derivation path.
    However, it is difficult to modify 4-Iodotoluene. Although iodine atoms are active, the reaction conditions need to be precisely controlled, otherwise the yield of side reactions will decrease. And its aromatic hydrocarbon structure is stable, in order to change its properties, we need to find a strong catalytic method. Therefore, we should diligently study new ways to improve 4-Iodotoluene and modification, so that it can be used in the chemical and pharmaceutical industries to the best of its ability and benefit the world.
    Synonyms & Product Names
    Today there is a product called 4-Iodotoluene. Its aliases are also common, such as p-iodotoluene. This product is widely used in the field of chemical industry. It can be used as a raw material for organic synthesis and participates in various reactions to produce various useful compounds.
    In the market, its trade names are also different. However, its essence is 4-Iodotoluene. Its properties are stable, and under suitable conditions, it can exhibit unique chemical properties.
    Chemical industry masters, study this product in order to expand its use and optimize the preparation method. It is hoped that we can obtain higher quality 4-Iodotoluene in a better way to meet the needs of all parties and promote the progress of the chemical industry.
    Safety & Operational Standards
    4-Iodotoluene is also a chemical substance. If you want to destroy it, you must first understand its safety and operation conditions before you can protect it.
    Anyone who involves 4-Iodotoluene must use it. When entering the room, put on the clothes you use, keep your eyes on it, and wear anti-chemical gloves to avoid its harm.
    Store its things, and it is advisable to put it in the clothes of the dry, and the oxidized materials of the fire source. Take it, and use it in the dry, and make it a container, so as not to overflow.
    If it is used in the reaction, the control and force will be reversed. If you observe the reaction, if there is an image, stop the operation immediately, and solve the problem.
    If you use a 4-Iodotoluene device, you must not use it. According to the situation, it should be properly placed to prevent contamination of the environment.
    If you use a 4-Iodotoluene device, you must wash it in an appropriate way, dry it, and keep it in place.
    If you use a 4-Iodotoluene device, you must use it. The safe operation of 4-Iodotoluene must be done by those who use it. Only by doing it can you ensure the safety of the product and the safety of your own environment.
    Application Area
    4-Iodotoluene is also an organic compound. It is used in various fields and is widely used. In the field of pharmaceutical creation, it can be used as an intermediate to help the research of new drugs. Such as the preparation of antibacterial agents, or drugs with curative effects on certain diseases, 4-Iodotoluene is often a key material.
    In materials science, it also shows its ability. It can participate in the synthesis of special materials to make materials unique, such as improved optical or electrical properties, and can be used in optoelectronic devices, semiconductor materials, etc.
    In the field of fine chemicals, 4-Iodotoluene can be used to make fine chemicals such as fragrances and dyes, enhancing its quality and characteristics, and meeting various market demands. Therefore, 4-Iodotoluene has important value in many application fields.
    Research & Development
    Yu Taste is dedicated to the research of 4-Iodotoluene. This substance has unique properties and has great potential in many fields of chemical industry. At the beginning of research, analyze its structure, identify its properties, and explore the method of synthesis.
    In order to find the best method, I went through ancient books and tried the formula repeatedly. After months of research, I first obtained a method, but the purity of this product was not high. Then I dedicated myself to improving, considering various factors of reaction, such as temperature, pressure, catalyst, etc.
    With unremitting efforts, the synthesis method was gradually perfected, and the purity and yield of 4-Iodotoluene produced were significantly improved. This achievement may lay the foundation for its wide application in materials, medicine, and other fields, and is expected to promote the development of related industries in the future. I should also continue to study it, hoping to make more progress.
    Toxicity Research
    In recent years, I have studied chemical substances, especially 4-Iodotoluene, to observe its toxicity, hoping to gain something.
    At the beginning, take the number of 4-Iodotoluene, place it in various utensils, and measure it by different methods. Observe its combination with other things, observe its changes, and record its situation. And make insects, plants and trees close to it, depending on its impact.
    Over time and months, there is something to be gained. 4-Iodotoluene is toxic. If it is touched, insects or stiff, plants or withered. If it enters the body, it will also harm health, damage the viscera, and mess with qi and blood.
    However, its poison must be controlled, and it can be prevented by correct techniques. In the workplace, when the gas is ventilated, wear protective equipment; after use, handle it carefully and do not pollute the environment.
    My generation studies the toxicity of this thing, and hopes that the world will use it carefully to avoid its harm and make the best use of it, without suffering from the body and environment.
    Future Prospects
    Today, there is a thing called 4-Iodotoluene. In the field of my chemical research, its future prospects can be seen. This thing has unique characteristics and may be of great use in various chemical processes and pharmaceutical research and development.
    Looking at its chemical structure, it seems to hide endless potential. With time, with the power of scientific and technological progress, it may be able to emerge in the road of material innovation. Make the material have special properties, apply it to cutting-edge equipment, and contribute to the progress of industry.
    In the field of medicine, 4-Iodotoluene may be the basis for the creation of new drugs. Through exquisite synthesis, it becomes a special effect, relieving the pain of disease and saving the body of all people.
    Our generation should study diligently, explore its principles, and expand its path. Looking forward to the future, see 4-Iodotoluene shining brightly, helping humanity progress and creating brilliant achievements. This is the ambition of our chemical researchers.
    Historical Development
    4-Iodotoluene is also an organic compound. The evolution of its history is quite worth studying. At the beginning, the sages of chemistry studied the way of organic synthesis diligently. In the past, scholars tried their best to make these compounds.
    At that time, the technology was not exquisite, and the preparation method was difficult and complicated. After several generations of perseverance, progress has gradually been made. In the past, the synthesis of raw materials was rare and the techniques were simple.
    However, chemists persevered and tried new methods. After a long period of exploration, the preparation method has gradually become mature. From the crude beginning to the state of sophistication, the preparation technology of 4-Iodotoluene has improved day by day. It is of crucial significance in the development of organic chemistry, laying the foundation for the research and creation of more compounds in the future, and creating a new situation.
    Product Overview
    4-Iodotoluene is an organic compound. It is a colorless to pale yellow liquid with a special odor. This substance is widely used in the field of organic synthesis.
    Its preparation method is often obtained from toluene as the starting material through the reaction of iodization. The iodization process requires appropriate reaction conditions, such as the use of catalysts, temperature and time control, etc., to obtain a higher yield.
    In terms of properties, the physical properties such as boiling point and melting point of 4-Iodotoluene have their own specific values, which are important in the operation of separation and purification. Its chemical properties are also active, and it can participate in a wide range of chemical reactions, such as nucleophilic substitution reactions, etc., resulting in the derivation of a variety of organic products. It plays a key role in drug synthesis, materials science, and many other fields. It is a substance that cannot be ignored in organic chemistry research.
    Physical & Chemical Properties
    4-Iodotoluene is also an organic compound. It has specific physical and chemical properties. Looking at its physical properties, at room temperature, it is a colorless to light yellow liquid with a special odor. Its boiling point is quite high, due to the force between molecules. As for chemistry, the benzene ring is connected to iodine atoms and methyl groups. Iodine atoms have certain electron-withdrawing properties, and methyl groups are the power supply radical. The two affect each other, resulting in unique chemical activities. It can participate in many chemical reactions, such as nucleophilic substitution reactions, and iodine atoms can be replaced by other nucleophilic reagents. And because of its structural characteristics, it is often an important raw material in the field of organic synthesis. It can prepare a variety of organic products through different reaction paths, which is of great value in chemical research and industrial production.
    Technical Specifications & Labeling
    4-Iodotoluene is also an organic compound. The technical specifications and labeling (product parameters) for its preparation are related to the quality and application of this chemical.
    When preparing, strict procedures need to be followed. The choice of raw materials, when pure, the proportion is precisely adjusted. The reaction conditions, such as temperature and pressure, need to be properly controlled. High temperature will cause the reaction to be too fast, prone to side effects; low temperature will cause the reaction to be slow, time-consuming and laborious. The same is true for pressure, and moderate pressure can promote the smooth flow of the reaction.
    In the label, the product parameters are the key. Its purity geometry is related to the wide range of uses. The amount of impurities must be strictly controlled within the limit. And its physical properties, such as melting point and boiling point, must also be clearly marked for the user's reference. In this way, the quality of 4-Iodotoluene can be guaranteed, and it can be used effectively in the fields of chemical industry and scientific research.
    Preparation Method
    There are ways to make 4-Iodotoluene today. The raw materials are toluene and iodine. Toluene is used as the base to combine with iodine. In this reaction step, the toluene is first placed at a suitable temperature, and a catalyst is added to it. The catalyst can make the reaction fast and smooth.
    When the reaction is taking place, be careful to control the temperature, and do not make the temperature change abruptly, causing the reaction to be chaotic. After it is completed, there is a process to deal with it. By the method of separation, the product is separated from the rest to obtain pure 4-Iodotoluene. The method of separation, either by distillation or by extraction, is selected according to the situation.
    The chemical mechanism for making this is that the structure of toluene encounters iodine, and under catalysis, hydrogen is replaced by iodine to form 4-Iodotoluene. In this process, the raw materials are carefully selected, and the reaction control and treatment sequence are required to obtain the best product.
    Chemical Reactions & Modifications
    In today's research, there are some possible reasons for the inversion of 4-Iodotoluene. Its inversion often follows specific principles. Under the condition of multiple inversion, it shows different chemical properties.
    In case of a specific inversion, the iodine atom in its molecule is prone to substitution and inversion. Due to the good activity of the iodine atom, it can be placed by other groups, and the molecular integrity can be changed. This substitution inversion can be changed according to factors such as the proportion of the inverse, the degree of inversion, and the solubility.
    And its chemical properties are also affected by benzene shadow, and the daughter cloud of benzene makes 4-Iodotoluene have special inversion activity. In some inversions, benzene co-acts, resulting in a change in the rate of inversion. For many times, it is clear that the integration of the reverse parts can effectively control their transformation, improve their performance, and achieve ideal results. This is of great significance to the research and engineering of the chemical industry.
    Synonyms & Product Names
    4-Iodotoluene is also a chemical substance. Its name is also the same. In the field of chemical chemistry, this substance or iodine toluene. Iodine toluene, the name is its own, because the iodine atom occupies the position of toluene.
    The name of its product also exists in the world. The market has such a product for the needs of chemical research and manufacturing. Those who study this product often use it interchangeably under the name of the same product to clarify its nature and study its performance.
    In the field of chemical chemistry, 4-Iodotoluene is often an important raw material, which can be synthesized to help other products. The name of the same product, the name of the product, and the name of the product refer to the same thing. They are all used for research and development, and promote the development of the product to help the work.
    Safety & Operational Standards
    4-Iodotoluene product safety and operating specifications
    4-Iodotoluene is also an essential product for chemical processing. When it is used for research and development, safety regulations are the most important, and it is related to the safety of everyone and the smooth operation of the industry.
    In terms of safety, it has certain hazards. This product may irritate the eyes, skin and exhalation tract. When touching the skin, rinse it with a lot of water as soon as possible, and remove the contaminated clothes. If you feel unwell, seek medical attention. When entering the eyes, support the eyelids and rinse with flowing water or normal saline, you also need to seek medical attention. If inhaling, leave the scene quickly to a new place to keep breathing, such as breathing difficulties, oxygen delivery, respiratory arrest, cardiopulmonary resuscitation and emergency medical treatment. If you take it by mistake, do not induce vomiting, drink warm water, and seek medical attention.
    4-Iodotoluene is flammable, flammable in case of open flames and hot topics. When storing and transporting, it should be placed in a cool and ventilated warehouse, away from fire and heat sources. The warehouse temperature should not exceed 30 ° C. Keep the container sealed. Store separately with oxidants and acids, and avoid mixed storage. When handling, pack lightly and unload lightly to prevent package leakage.
    As far as operating specifications are concerned, operators should receive professional training and strictly follow the regulations. When operating, ventilating equipment is required to reduce the concentration in the air. Wear chemical safety glasses, gas masks, chemical protective clothing, and chemical gloves. Keep away from fire and heat sources, and smoking is prohibited in the operation area. Use explosion-proof ventilation system and equipment to prevent steam leakage. Control the flow rate during filling, and have a grounding device to remove static electricity. Equipped with fire extinguisher materials and leakage emergency treatment equipment.
    Disposal is also exquisite. According to national laws and regulations, it should be handled with qualifications. Do not discard the pollution-free ring at will. Only in this way can we ensure safety in the research and use of 4-iodotoluene, follow the norms, and promote the progress of the industry.
    Application Area
    4-Iodotoluene is also a chemical substance. Its application domain is also important. In the field of synthesis, it can be used as an important raw material to help new research, or involved in antibacterial and anti-cancer research. In the field of materials, it can be used to create special materials, such as materials with special properties and optical properties. It is also used in synthetic materials, which are used for the construction of molecular materials. Due to its special chemical properties, it can lead to a variety of inverse effects, such as even inverse effects, etc., in order to expand the development of chemical compounds, and promote the development of chemical engineering.
    Research & Development
    4-Iodotoluene is also an organic compound. Our generation has been studying this substance for a long time. At the beginning, to obtain high-purity 4-iodotoluene, the road to experimentation was full of thorns. The choice of raw materials and the rules of reaction need to be studied in detail.
    After many attempts, in the proportion of reactants, temperature control, etc., the method has finally been refined. The purity of the product is also high. Looking at its application, it has emerged in the field of pharmaceutical synthesis, and can be used as a key intermediate, paving the way for the birth of many good medicines.
    Looking to the future, we hope to expand its use and find new ways in the fields of new material research and development. Continuing to study, we hope that the development of 4-iodotoluene will continue to rise, adding to the progress of chemistry.
    Toxicity Research
    4 - Toxicity Study of Iodotoluene
    The husband of 4 - Iodotoluene, the thing that dissolves. Today's investigation of its toxicity is the family's.
    In the environment of the animal, cast 4 - Iodotoluene in the image of the white mouse. On the seventh day, check its form, spirit and physiology. The white rat may be tired, eat less, and even be able to control the body.
    And analyze the effect of its internal organs. The liver, the main detoxification official, is affected by its shadow, and it can be replaced or reduced. The body also suffers, and the excretion is abnormal. All this shows that 4 - Iodotoluene is toxic.
    Re-examine its entry into the environment, or sewage and soil, and organisms are affected by it. Floating and algae are blocked, and their growth and reproduction are hindered.
    Therefore, the toxicity of 4-Iodotoluene cannot be ignored. It can be used for production and use, and it can be prevented to avoid its harm to organisms and environments.
    Future Prospects
    4-Iodotoluene is an organic compound. Looking at its current state, although it has been used in current industry and scientific research, we still see it as an endless future prospect.
    In today's world, science and technology are changing day by day. In the field of materials science, 4-Iodotoluene may become the basis for new materials. Its unique structure and unique properties may help researchers make more tough, durable and special materials to meet the needs of aerospace, electronics and other industries.
    In medicinal chemistry, 4-Iodotoluene also holds infinite possibilities. Or it can be turned into a good medicine for the world through a delicate synthesis path, healing various diseases, and saving patients from pain.
    Moreover, with the rise of the concept of green chemistry, optimizing the preparation process of 4-Iodotoluene to make it more environmentally friendly and efficient is also a major direction in the future. In this way, this compound will surely shine in the scientific and industrial arena of the future, and create extraordinary achievements for the well-being of mankind.
    Where to Buy 4-Iodotoluene in China?
    As a trusted 4-Iodotoluene manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
    Frequently Asked Questions

    As a leading 4-Iodotoluene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 4-iodotoluene?
    4-Iodotoluene is 4-iodotoluene, and its main uses are as follows.
    First, it is often used as a key intermediate in the field of organic synthesis. Many organic compounds with special structures and functions can be derived through various chemical reactions, such as nucleophilic substitution, coupling reactions, etc. Taking the Suzuki coupling reaction as an example, 4-iodotoluene can react with boron-containing organic compounds under palladium catalysis to form carbon-carbon bonds. This reaction is of great significance in the fields of medicinal chemistry and materials science. It helps to synthesize complex organic molecules and lays the foundation for the creation of new drugs and the development of high-performance materials.
    Second, it is quite useful in pharmaceutical research and development. Due to its unique structure, it can be chemically modified into specific drug molecular structures, which affects the activity, solubility, and targeting properties of drugs. In the synthesis of some anti-cancer drugs, 4-iodotoluene is involved, providing the possibility for the development of more efficient anti-cancer drugs with low toxicity and side effects.
    Third, in the field of materials science, 4-iodotoluene can be prepared by polymerization and other means with special electrical and optical properties Polymer materials. For example, the synthesis of conductive polymer materials, photoluminescent materials, etc., show application potential in electronic devices, display technology and other fields, and promote the development and innovation of related technologies.
    Fourth, it has also made contributions in the field of dye synthesis. With the characteristics of iodine atom and toluene group, it can participate in the construction of chromophore structure, prepare bright-colored and stable dyes, which are used in textile, printing and other industries to provide diverse options for dyeing processes.
    What are the physical properties of 4-iodotoluene?
    4 - iodotoluene, a chemical substance, is also vulgar iodine toluene. Its physical properties are as follows, as described by you today.
    First of all, its appearance is often white to light-colored crystalline, and it is difficult to determine the location. Its melting temperature is between 35 and 37 ° C. At this degree, the solid solution of 4 - iodotoluene is difficult to melt. Because of this melting characteristic, it can cause its properties in a specific environment. In the field of chemical operations and other fields, this property is especially important.
    Furthermore, its boiling temperature is 211 - 212 ° C. When the temperature rises to the stressful value, 4-iodotoluene will be released from the liquid. This boiling property is difficult to achieve in the process of separation and other processes. By controlling the temperature near the boiling, it can effectively divide 4-iodotoluene into other substances for the purpose of improvement.
    And solubility, 4-iodotoluene is soluble in water, but it has good solubility in many solvents, such as ethanol, ether, benzene, etc. This property makes 4-iodotoluene in the process of synthesis and isochemical process. It can be used for high solubility and high solubility, because it can be dispersed in the solution, which is conducive to the full bonding of the reactor, and promotes the reaction.
    In addition, 4-iodotoluene has a certain density, which is higher than that of water, at 1.709 g/cm ³. This density characteristic makes it convenient to distinguish between operations involving liquid-liquid separation, etc., according to the difference in water density.
    In addition, 4-iodotoluene's general physical properties, melting, boiling, solubility and density, etc., play an important role in chemical synthesis, extraction, and other chemical engineering and chemical research fields, providing an indispensable basis for the operation of phase engineering.
    What are the chemical properties of 4-iodotoluene?
    4-Iodotoluene, the Chinese name for 4-iodotoluene, is a kind of chemical compound. Its chemical properties are special, and I will tell you about it today.
    First of all, its substitution is reversed. The iodine atom activity of 4-iodotoluene is very good, and it can cause nuclear substitution in multiple nuclei. For example, when encountering the group, the iodine atom is replaced by the group, and the group of the phase is substituted for toluene. This reverse can be extended to the compound, which has a wide range of uses in the synthesis of. its reason is that the rich sub-region of the nucleus attacks the iodine atom, the, to generate new compounds.
    4-Iodotoluene can be reacted in the same way as the Suzuki catalyst. In this reaction, 4-iodotoluene-arylboronic acid can generate aryl compounds in the presence of catalysis and catalysis. This reaction is an important means to build carbon-carbon emissions, which is very important in the fields of chemical synthesis, materials science, etc. The reaction process involves the coordination of catalysis, oxidative addition, metallization, and the elimination of the original.
    Furthermore, the benzene of 4-iodotoluene also has a certain activity. It can be substituted in the field of aromatics. Due to the presence of methyl groups, the density of the benzene sub-cloud can be increased, so it is more susceptible to attack. For example, under suitable conditions, nitrification can be used to cause nitrification and inverse effects, and nitro groups are introduced to benzene. This inverse property also affects the positioning effect of methyl groups, mainly generating gold and gold substitutes.
    And because of its iodine-containing atoms, 4-iodine toluene can be used for metallization. Some gold or gold compounds interact, and iodine atoms can be dislocated by gold to form gold compounds. This compound has high activity and can be used for more synthetic inverse reactions. It is used for the production of high-quality molecules.
    Therefore, 4-iodotoluene, due to the existence of iodine atoms and methyl groups, has a wide range of chemical properties, and can be used in the synthesis of many different compounds. It is important for chemical research and engineering.
    What are the synthesis methods of 4-iodotoluene?
    4-Iodotoluene is also an organic compound, and there are many ways to synthesize it. The following are the common numbers:
    First, toluene is used as the starting material and is prepared by halogenation reaction. 4-Iodotoluene can be formed from toluene and iodine under appropriate catalyst and reaction conditions. Usually catalysts such as iron filings or ferric chloride are required. The mechanism of this reaction is that iodine generates iodine positive ions under the action of a catalyst, and then undergoes electrophilic substitution with the benzene ring of toluene. The methyl group of the benzene ring is an ortho-para-locator, so the iodine atom mainly replaces the para-position of the benzene ring methyl to obtain 4-iodotoluene as the main product, but a small amount of ortho-substituted products are also formed.
    Second, starting from p-toluidine. First, p-toluidine is diazotized, and p-toluidine is treated with sodium nitrite and hydrochloric acid at low temperature to form a diazonium salt. Then, the diazonium salt is reacted with potassium iodide, and the diazonium group is replaced by an iodine atom to obtain 4-iodotoluene. The advantage of this method is that the reaction selectivity is high, and the substitution side reactions at other positions can be effectively avoided to obtain a purer 4-iodotoluene product.
    Third, p-toluene boronic acid is used as the raw material. Let p-toluene boronic acid react with iodine reagents, such as iodine elemental or N-iodosuccinimide (NIS), in the presence of suitable bases and cataly This reaction is a palladium-catalyzed cross-coupling reaction variant, which can efficiently introduce iodine atoms into the benzene ring para-position, and has the characteristics of mild reaction conditions and high yield.
    All these synthesis methods have their own advantages and disadvantages. The halogenation method is easy to obtain raw materials, but the selectivity is slightly less; the diazotization method has good selectivity, but the steps are slightly complicated; the method using p-methylphenylboronic acid as raw material is efficient, but the raw material cost may be higher. In practical applications, the appropriate synthesis path should be selected according to specific needs and conditions.
    What should be paid attention to when storing and transporting 4-iodotoluene?
    4-Iodotoluene is also an organic compound. When storing and transporting, many matters must be paid attention to.
    First of all, storage, because it has a certain chemical activity, should be stored in a cool and ventilated warehouse. This is to avoid high temperature causing it to react chemically and cause danger. The temperature of the warehouse should not be too high to prevent the material properties from changing. And it needs to be kept away from fire and heat sources. Open flames can easily cause it to burn and cause fire. In addition, it should be stored separately from oxidants, acids, bases, etc. These substances meet with it or react violently, causing accidents. The storage place should also be prepared with suitable materials to contain leaks for emergencies.
    As for transportation, there are also important rules. Before transportation, make sure that the container is well sealed to prevent leakage and volatilization. During transportation, the speed of the vehicle should not be too fast, and avoid sudden braking to prevent damage to the container. Transportation vehicles must be equipped with corresponding types and quantities of fire-fighting equipment and leakage emergency treatment equipment. Escort personnel must be familiar with the nature of the goods transported and emergency disposal methods. If there is a leak during transportation, appropriate measures should be taken immediately to evacuate the crowd, seal the scene, properly handle the leak, and do not panic.
    In this way, when storing and transporting 4-iodotoluene, pay careful attention to the above things, so that security is safe.