4 Trans 4 Ethyl Cyclohexyl Iodobenzene

The analysis of the chemical structure of 4-trans (4-ethylcyclohexyl) iodobenzene is related to the category of organic chemistry. The name of this compound is derived according to the naming rules of organic compounds, from which the outline of its structure can be inferred.
"4 -" indicates that the substitution is based on the position of the benzene ring. The benzene ring is a six-membered carbon ring with a conjugated system and stable properties. It is the core structure of the compound.
The term "trans" is used in organic chemistry. In the cyclohexyl structure, it refers to the spatial arrangement of specific substituents as trans. Cyclohexyl is a ring-like structure composed of six carbon atoms, with chair-like and boat-like conformations with different stability. The chair-like conformation has a lower energy and is more common.
"4-ethyl" indicates that there is an ethyl group attached to the 4-position carbon of cyclohexyl. Ethyl is the remaining group after ethane loses a hydrogen atom, namely - CH ² CH, which has a certain electron supply effect and can affect the electron cloud distribution and chemical properties of molecules.
"iodobenzene" is clear that the 4-position on the benzene ring is replaced by an iodine atom. The iodine atom has a relatively large relative atomic mass and moderate electronegativity. Its existence also has a significant impact on the physical and chemical properties of molecules, such as the polarity, boiling point, and chemical reactivity of molecules.
In summary, the structure of 4-trans (4-ethylcyclohexyl) iodobenzene is based on the benzene ring, with 4-ethylcyclohexyl containing the trans configuration at the 4-position, and iodine atoms at the 4-position of the benzene ring. The characteristics of this structure determine that it may have unique applications and reactivity in organic synthesis, materials science, and other fields.

4-Trans (4-ethylcyclohexyl) iodobenzene is an important raw material for organic synthesis. It has a wide range of uses and is of key significance in the fields of materials science and medicinal chemistry.
In the field of materials science, it is often used to prepare liquid crystal materials. Liquid crystals play a central role in display technology. This compound has a special structure that allows molecules to be arranged in an orderly manner, which in turn affects the phase state and properties of liquid crystals. By adjusting its structure and composition, the optical and electrical properties of liquid crystal materials can be optimized, such as improving the display contrast and response speed, making the display screen clearer and smoother, contributing greatly to the manufacture of liquid crystal displays.
In the field of pharmaceutical chemistry, it is a key intermediate for the synthesis of new drugs. Due to its iodine-containing atoms and specific ring structure, it can participate in a variety of chemical reactions to build complex drug molecular structures. For example, through cross-coupling reactions, it can be connected with other organic fragments, introducing specific functional groups, endowing drugs with unique biological activities, and helping to develop innovative drugs for treating specific diseases.
In addition, in organic synthetic chemistry research, 4-trans (4-ethylcyclohexyl) iodobenzene is also a commonly used reagent. Scientists can use its unique reactivity to explore novel reaction pathways and synthesis methods, expand the boundaries of organic synthesis, lay the foundation for the creation of more new organic compounds, and promote the continuous development of organic chemistry.

There are several methods for the synthesis of 4-trans - (4-ethylcyclohexyl) iodobenzene as follows.
First, iodobenzene and 4-ethylcyclohexylboronic acid are synthesized by Suzuki coupling reaction. This reaction needs to be carried out in a basic environment and catalyzed by palladium. Iodobenzene, 4-ethylcyclohexylboronic acid, base (such as potassium carbonate) and palladium catalyst (such as tetra (triphenylphosphine) palladium (0)) are placed in a suitable organic solvent (such as a mixed solvent of toluene, ethanol and water), heated and stirred. During the reaction, the palladium catalyst promotes the coupling of the carbon-iodine bond of iodobenzene with the carbon-boron bond of 4-ethylcyclohexyl boric acid, resulting in the formation of the target product 4-trans - (4-ethylcyclohexyl) iodobenzene. The advantage of this method is that the reaction conditions are relatively mild, the yield is quite high, and the substrate selectivity is good.
Second, it can be prepared from 4- (4-ethylcyclohexyl) aniline by diazotization and iodization. First, 4- (4-ethylcyclohexyl) aniline is reacted with sodium nitrite under acidic conditions (such as hydrochloric acid solution) to form diazonium salts. Subsequently, the diazonium salt reacts with potassium iodide, and the diazonium group is replaced by an iodine atom to obtain 4-trans- (4-ethylcyclohexyl) iodobenzene. This path step is slightly complicated, and the diazonation reaction needs to precisely control the temperature and reaction time to prevent the decomposition of diazonium salts. However, the raw material 4- (4-ethylcyclohexyl) aniline is relatively easy to obtain, and it is also a feasible method under specific circumstances.
Third, 4-bromoiodobenzene is synthesized by reacting with 4-ethylcyclohexyllithium reagent. 4-bromoiodobenzene is dissolved in anhydrous ether or tetrahydrofuran organic solvent, and 4-ethylcyclohexyllithium reagent is slowly added dropwise at low temperature. During the reaction, the carbon-lithium bond of the lithium reagent undergoes nucleophilic substitution of the carbon-bromo bond of 4-bromoiodobenzene to form 4-trans - (4-ethylcyclohexyl) iodobenzene. This method requires an anhydrous and oxygen-free environment and has strict operation requirements. However, it can effectively construct carbon-carbon bonds and is widely used in the field of organic synthesis.

4-Trans (4-ethylcyclohexyl) iodobenzene is one of the organic compounds. Its physical properties are as follows:
Looking at its appearance, under room temperature and pressure, it mostly shows a white to light yellow crystalline powder state. This color state characteristic is easy to identify and distinguish.
When talking about the melting point, it is about 110-114 ° C. The melting point is the critical temperature at which a substance changes from a solid state to a liquid state. This specific melting point range is an important physical characteristic for its identification and purification process. The boiling point is the temperature at which a substance converts from a liquid state to a gas state. However, the relevant information of this compound, or due to experimental conditions, has not been reported on the exact boiling point.
In terms of solubility, it is insoluble in water. Because water is a polar solvent, and the structural characteristics of this compound cause its polarity to be weak. According to the principle of "similar miscibility", it is insoluble in water. But it is soluble in common organic solvents, such as toluene, chloroform, dichloromethane, etc. Organic solvents have different polarities, and this compound can be soluble in this class, which shows that its structure and solvent molecules have certain interactions, which can form a homogeneous system. This solubility property is widely used in organic synthesis, extraction and separation and other fields.
In addition, its properties such as density and vapor pressure are not yet detailed due to research data limitations. However, the physical properties are related to each other, and in-depth research in the future may clarify more related properties. Its production, application, storage and other aspects are of great significance.

4-Trans (4-ethylcyclohexyl) iodobenzene, organic compounds are also. In today's chemical market, its prospects are promising. Cover because of its unique structure, in the field of materials science, is very useful.
At the end of Guanfu electronic materials, with the changing speed of electronic products, the demand for high-performance materials is increasing. 4-trans (4-ethylcyclohexyl) iodobenzene can be used as a raw material for organic semiconductor materials. Its unique molecular structure can endow materials with good charge transfer properties. It can improve device efficiency and stability in the manufacture of organic Light Emitting Diode (OLED), organic field effect transistor (OFET) and other devices. Therefore, the market demand for it is expected to grow with the vigorous development of the electronics industry.
In the field of medicinal chemistry, this compound may be a key intermediate for the synthesis of new drugs. Its special carbon ring structure and iodine atom can participate in a variety of chemical reactions, helping chemists build complex drug molecular structures to deal with various disease challenges. Although the current relevant medicinal research may be in the early stage, the active field of pharmaceutical research and development makes it possible to develop new therapies in the future, thus driving up market demand.
Furthermore, the field of liquid crystal materials should not be underestimated. The molecular shape and polarity characteristics of 4-trans (4-ethylcyclohexyl) iodobenzene make it expected to become a key component of liquid crystal formulations, helping liquid crystal materials to obtain better phase transition temperature range and optical properties. With the continuous innovation of display technology, the demand for liquid crystal materials is stable, and its market prospect is also considerable.
Although the current market size may be limited, with the in-depth research and industrial expansion of various application fields, 4-trans (4-ethylcyclohexyl) iodobenzene will welcome a broad development space and emerge in the chemical products market.