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What is the chemical structure of 2-bromo-7-iodine-4H-pyrrolido [2,3-b] pyrazine (9CI)?
2-% bromo-7-chloro-4H-pyrrolido [2,3-b] pyridine (9CI) is an organic compound with a unique chemical structure. It is formed by the conjugation of pyridine and pyrrole, and is connected with bromine and chlorine atoms at specific positions.
The core structure of this compound is pyrrolido [2,3-b] pyridine, which is a fused ring system composed of pyridine ring and pyrrole ring. The pyridine ring contains 6 carbon atoms and 1 nitrogen atom in the form of a six-membered ring; the pyrrole ring contains 4 carbon atoms and 1 nitrogen atom in the form of a five-membered ring. The two are conjugated in a specific way to form a unique fused ring structure.
In this fused ring system, "2-bromine" means that the bromine atom is attached to the carbon atom numbered 2 in the pyrrolido [2,3-b] pyridine fused ring system; "7-chlorine" means that the chlorine atom is attached to the carbon atom numbered 7. The introduction of these halogen atoms endows the compound with unique chemical and physical properties.
The electronegativity of the halogen atom is relatively large, which will affect the distribution of molecular electron clouds, thereby changing its reactivity and physical properties. For example, bromine and chlorine atoms can participate in nucleophilic substitution reactions, coupling reactions, etc., providing the possibility for the derivatization of the compound, and have important application value in organic synthesis, pharmaceutical chemistry and other fields. Due to its unique chemical structure, it may also exhibit specific biological activities, making it a potential lead compound in fields such as drug discovery.
What are the physical properties of 2-bromo-7-iodine-4H-pyrrolido [2,3-b] pyrazine (9CI)
2-% cyanogen-7-nitrogen-4H-pyrrolido [2,3-b] pyridine (9CI) is an organic compound. The physical properties of this substance can be described in the following aspects.
First, its appearance is either a solid state at room temperature and pressure. Its specific color and crystal form vary depending on the preparation method and purity. Or it is a white, light yellow crystalline powder with fine powder and uniform texture.
Second, its melting point is determined by fine experiments to be within a certain temperature range. This temperature is the critical temperature for the transformation of its solid state to a liquid state. At this temperature, the intermolecular forces change and the lattice structure disintegrates.
In addition, its solubility, in organic solvents, such as common ethanol, dichloromethane, etc., has a certain solubility. Ethanol is a polar organic solvent, and it can interact with the compound molecules by hydrogen bonds, van der Waals forces, etc., so it can dissolve part of the substance; the polarity and molecular structure of dichloromethane also enable it to interact with 2-% cyanogen-7-nitrogen-4H-pyrrolido [2,3-b] pyridine to disperse in it. In water, due to the ratio of polar groups to non-polar groups in its molecular structure, its solubility is low. Water is a strong polar solvent, and the interaction between the molecules of the compound is not enough to overcome the force between the molecules themselves, so it is difficult to dissolve.
In terms of its density, compared with common water, there is a specific value. This value reflects the mass per unit volume, which can help to anticipate the phenomenon of stratification with other substances when it involves mixing and separation operations.
In terms of stability, under normal environmental conditions, it has certain chemical stability. When encountering strong oxidizing agents, strong acids, strong bases and other chemical reagents, the cyano group, nitrogen heterocyclic ring and other parts of the molecular structure, or due to the distribution of electron cloud density, undergo chemical reactions, resulting in structural changes. And under high temperature, light and other conditions, the chemical bond energy within the molecule increases, or structural changes may be triggered, such as isomerization, decomposition and other reactions.
What are the main uses of 2-bromo-7-iodine-4H-pyrrolido [2,3-b] pyrazine (9CI)?
2-% quinoline-7-one-4H-pyrrolido [2,3-b] pyridine (9CI) is an organic compound whose main use is critical in the field of medicinal chemistry and organic synthesis.
In the field of medicinal chemistry, it can be used as a lead compound because its unique chemical structure can interact with specific targets in organisms. Many diseases, such as cancer and neurological disorders, are caused by abnormal biological processes in vivo, and specific target proteins play an important role in these abnormal processes. The structure of this compound may be modified and modified to precisely fit the activity check point of the target protein, and then regulate related biological processes to achieve the purpose of treating diseases. For example, by adjusting its substituents, its affinity with the target, pharmacokinetic properties can be optimized, and the efficacy and safety of the drug can be improved.
In the field of organic synthesis, 2-quinoline-7-ketone-4H-pyrrolido [2,3-b] pyridine (9CI) can be used as a key intermediate. Organic synthesis aims to build complex organic molecules, and the unique structure of this compound lays the foundation for the synthesis of more complex and functional organic molecules. With the help of organic synthesis methods, it can be used as a starting material to introduce different functional groups through a series of chemical reactions, such as nucleophilic substitution, cyclization, etc., to expand the molecular skeleton and synthesize organic compounds with novel structures and properties, providing a variety of compound options for materials science, natural product total synthesis and other fields.
In summary, 2-quinoline-7-ketone-4H-pyrrolido [2,3-b] pyridine (9CI) plays an indispensable role in drug development and organic synthesis, and is of great significance to promote the development of related fields.
What are the synthesis methods of 2-bromo-7-iodine-4H-pyrrolido [2,3-b] pyrazine (9CI)
The synthesis method of 2-% cyanogen-7-nitrogen-4H-pyrrolido [2,3-b] pyridine (9CI) is a key research direction in the field of chemical synthesis. The following are several common synthetic paths:
One is to use pyridine derivatives as starting materials. A specific substituted pyridine can be selected. By introducing functional groups such as cyano and nitrogen atoms into the pyridine ring, a series of reactions such as nucleophilic substitution and cyclization can be achieved to achieve the construction of the target compound. This path requires fine control of reaction conditions, such as temperature, type and dosage of catalysts, etc., to ensure that the reaction proceeds in the desired direction and improve the yield and purity of the target product.
Second, starting from pyrrole derivatives. First prepare pyrrole containing specific substituents, and then gradually build a pyridine ring structure through ingenious reaction strategies, and introduce cyanyl and nitrogen atoms at the same time. In this process, the reaction sequence and the choice of reagents are crucial, and unnecessary side reactions need to be avoided in order to obtain the target product efficiently.
Third, use the reaction strategy of transition metal catalysis. With the help of transition metal catalysts, such as palladium, copper and other metal complexes, the construction of carbon-nitrogen and carbon-carbon bonds is achieved, so as to build the core skeleton of the target compound. This method usually has the advantages of mild reaction conditions and high selectivity, but it requires high activity and stability of the catalyst, and the cost of the catalyst may affect the overall synthesis cost.
When synthesizing 2-% cyanogen-7-nitrogen-4H-pyrrolido [2,3-b] pyridine (9CI), researchers need to carefully select the appropriate synthesis method according to their own experimental conditions, raw material availability, and product purity and yield requirements, and optimize the reaction conditions to achieve efficient, economical and environmentally friendly synthesis goals.
What is the market outlook for 2-bromo-7-iodine-4H-pyrrolido [2,3-b] pyrazine (9CI)?
2-Chloro-7-aza-4H-pyrrolido [2,3-b] pyridine (9CI), which is used in the field of pharmaceutical and chemical industry, has broad application prospects. Looking at its market prospects, it can be analyzed from multiple aspects.
From the perspective of pharmaceutical research and development, the nitrogen-containing heterocyclic structure occupies a key position in many drug molecules. The unique structure of 2-chloro-7-aza-4H-pyrrolido [2,3-b] pyridine may endow it with various biological activities. In the field of anti-cancer drug research and development, many studies have used this structural analogue as a basis to explore its inhibitory effect on cancer cell proliferation. Because it can bind to the target in cancer cells by a specific mechanism, block the growth signaling pathway of cancer cells, and then achieve the purpose of inhibiting cancer cells, there is great room for development in the anti-cancer drug market.
In the field of drugs for the treatment of neurological diseases, such compounds may have the ability to modulate the activity of neurotransmitters. For example, for neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, the structure can be modified or drugs that can modulate the secretion and delivery of neurotransmitters can be developed to improve patient symptoms. The market demand in this field is huge and the growth trend is significant. 2-chloro-7-aza-4H-pyrrolido [2,3-b] pyridine is expected to get a share of this.
From the perspective of the field of chemical materials, it can be used as an intermediate in organic synthesis. With its unique structure and reactivity, it can participate in many organic synthesis reactions to synthesize materials with special properties. For example, in the synthesis of optoelectronic materials, the introduction of this structure or the endowment of materials with unique optoelectronic properties can be used to manufacture new display materials, solar cell materials, etc. With the rapid development of the electronic information industry, the demand for new optoelectronic materials has surged, providing a broad market opportunity for 2-chloro-7-aza-4H-pyrrole [2,3-b] pyridine.
However, its market development also faces challenges. The complexity of the synthesis process or the high production cost limit large-scale production and marketing activities. Moreover, the research and development cycle of new drugs is long and the investment is huge. From compound discovery to the final drug launch, multiple rounds of clinical trials are required, and the success rate is low. But overall, with the progress of science and technology and in-depth research, if the synthesis problem can be overcome and the cost can be reduced, the market prospect of 2-chloro-7-aza-4H-pyrrole [2,3-b] pyridine is still bright.
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