5 Acetamido N N Bis 2 3 Dihydroxypropyl 2 4 6 Triiodoisophthalamide

5-Acetamido - N, N - bis (2,3 - dihydroxypropyl) - 2,4,6 - triiodoisophthalamide, often called iohexanol in Chinese, is a contrast agent widely used in the field of medical imaging.
Its main purpose is to help doctors observe the internal structure of the human body more clearly. When introduced into the human body, with the characteristics of high absorption of X-rays by the iodine element contained in it, it can make specific tissues or organs contrast sharply with surrounding tissues in the imaging process of X-rays, CT and other imaging examinations, thereby highlighting their morphology, location and presence or absence of lesions.
In angiography, iohexanol is injected into blood vessels, which can accurately show the course and diameter of blood vessels, as well as whether there are stenosis, blockage, and deformity. It provides a key basis for the diagnosis of vascular diseases, such as coronary heart disease and cerebrovascular diseases. In urography, it can help doctors understand the shape and function of organs such as kidneys, ureters, and bladders, and is of great significance for the diagnosis of diseases such as urinary stones and tumors. The use of iohexanol in enhanced CT scans can significantly improve the contrast between diseased tissue and normal tissue, and help to more accurately detect lesions and judge their properties, such as differentiating between benign and malignant tumors. In general, 5-acetamido - N, N - bis (2,3 - dihydroxypropyl) - 2,4,6 - triiodoisophthalamide plays an important role in modern medical imaging diagnosis, which greatly promotes the accuracy and efficiency of disease diagnosis.

5 - acetamido - N, N - bis (2,3 - dihydroxypropyl) - 2,4,6 - triiodoisophthalamide is an organic compound, often used as a contrast agent, widely used in the field of medical imaging. However, it also has some side effects, which are detailed below.
One of its side effects is an allergic reaction. This drug may cause skin symptoms such as rash, itching, hives, etc., which is an abnormal reaction of the immune system to the compound. Severe cases can cause angioedema, causing respiratory obstruction, which is life-threatening. Furthermore, it can cause nausea, vomiting, abdominal pain and other gastrointestinal discomfort. The drug enters the body, or interferes with the normal peristalsis and digestive function of the gastrointestinal tract, causing patients to feel abdominal discomfort, affecting normal diet and life.
Some patients may experience neurological symptoms such as dizziness and headache after taking the drug. This may affect the normal electrical activity and neurotransmitter transmission of the nervous system, causing patients to feel dizziness and pain in the head, affecting their mental state and daily activities. The cardiovascular system may also be affected, which can cause changes in blood pressure, such as increased or decreased blood pressure, and can also cause arrhythmias. Blood pressure fluctuations and arrhythmias can both have adverse effects on the normal pumping function of the heart, and in severe cases can cause serious consequences such as cardiac insufficiency.
In addition, long-term or large-scale use of this compound may cause damage to kidney function. Because it is excreted through the kidneys or deposited in the kidneys, it affects the normal function of glomeruli and renal tubules, resulting in abnormal renal function indicators, and in severe cases, it can develop into renal failure.
When clinical application of this drug, doctors should carefully observe the patient's physique and medical history, weigh the pros and cons, and closely monitor the patient's reaction after administration, and deal with all side effects in a timely manner to ensure patient safety.

5-Acetamido-N, N-bis (2,3-dihydroxypropyl) -2,4,6-triiodoisophthalamide, which is the chemical name of iohexanol, a medical contrast agent. Its applicable population is quite specific, as follows:
- ** Those who need medical imaging examination **: If people want to clearly observe the morphology and function of their internal organs and blood vessels, such as CT enhanced scanning, angiography and other examinations, iohexanol is a right-hand assistant. Taking people suspected of having cerebral vascular lesions as an example, after injecting iohexanol, with the help of CT scan, they can clearly see the blood vessels in the brain, whether there is stenosis or deformity, and help doctors make accurate diagnoses.
- ** People with basically normal renal function **: Iohexanol is mainly excreted through the kidneys, so normal renal function can ensure its smooth excretion. If the renal function is seriously damaged, the drug is easy to accumulate in the body, increase the burden on the kidneys, and cause the deterioration of renal function. Generally speaking, those with a glomerular filtration rate > 30ml/min/1.73m ² are relatively safe to use iohexanol. Of course, the specific needs to be determined by the doctor according to the individual condition of the patient.
- ** Those without a history of serious allergies **: Although the incidence of allergic reactions to iohexanol is low, those who have had a history of severe allergies to iodine or contrast agents, such as anaphylactic shock, laryngeal edema, etc. If they use this drug again, the risk of allergies is extremely high. Such Those who are allergic to other substances should also be cautious when using it. The doctor will evaluate the risk in advance and prepare anti-allergic rescue measures.
Remember that before using iohexanol, patients must truthfully inform the doctor of their own medical history, allergy history and other information to help the doctor weigh the advantages and disadvantages of the medication and ensure medical safety.

5-Acetamido-N, N-bis (2,3-dihydroxypropyl) -2,4,6-triiodoisophthalamide is also the name of a chemical substance. To use it properly, the first thing to do is to clarify its properties. This substance may be a genus of contrast agents. In the field of medical imaging, it is often used to increase the contrast between tissues and organs, and to help doctors clearly observe its state, position and work.
When used, it must follow the doctor's instructions, and the amount must be accurate. If the amount of coverage is small, it is difficult to show the effect of angiography, and the view is unknown; if the amount is large, it may lead to adverse reactions, such as allergies, mild skin rash, nausea and vomiting, severe cases or shock, endangering life.
And before use, you need to know the patient's history in detail. If there is a history of allergies, especially for those who are allergic to iodine, you should be cautious, or choose another method. The process of using it also requires medical care to closely monitor the patient's condition. If there is any difference, you should take countermeasures quickly.
And if it is stored, it must comply with the standard conditions. It often needs to be placed in a cool and dry place to avoid heat and moisture to prevent qualitative changes and lose its effectiveness. In this way, this substance can be used properly to help the doctor and protect the well-being of the patient.

5 - acetamido - N, N - bis (2,3 - dihydroxypropyl) - 2,4,6 - triiodoisophthalamide is the chemical name of the contrast agent iohexanol. This drug is widely used in the field of medical imaging, and the interaction with other drugs is very critical.
When used in combination with certain nephrotoxic drugs, such as aminoglycoside antibiotics, the risk is very high. Aminoglycosides are nephrotoxic, and iohexanol may also affect renal function. The use of both may greatly increase the risk of kidney damage, or cause serious consequences such as acute kidney injury.
In addition, it is also necessary to be cautious when sharing with metformin. During iohexanol imaging, it may affect the metabolism and excretion of metformin. Metformin is excreted through the kidneys. If iohexanol causes fluctuations in renal function, metformin is easy to accumulate in the body, causing lactic acidosis and endangering the patient's life.
When combined with diuretics, the situation is complicated. Small doses of diuretics may help the excretion of iohexanol to reduce adverse reactions; but large doses of powerful diuretics may cause dehydration and concentrate the blood. The concentration of iohexanol is relatively high, increasing the risk of adverse reactions, such as allergic reactions and kidney damage.
In addition, when combined with other contrast agents, although there are occasional clinical attempts, the risk is difficult to measure. The composition and physicochemical properties of different contrast agents are different, and the combination or increase the possibility of allergic reactions and other adverse reactions. It is not necessary and should not be easily combined. When a doctor uses this drug, he must carefully review the patient's medication history, weigh the pros and cons, avoid adverse interactions, and ensure the safety of the patient's medication.