5 Acetamido N1 N3 Bis 2 3 Dihydroxypropyl 2 4 6 Triiodoisophthalamide

5 - acetamido - N1, N3 - bis (2,3 - dihydroxypropyl) - 2,4,6 - triiodoisophthalamide, often called iohexanol in Chinese, is a key substance in the field of medical contrast agents.
Its main use is to play a developing role in X-ray computed tomography (CT) examination. Many organs and tissues of the human body have poor contrast in X-ray images in their natural state, making it difficult to distinguish clearly. After iohexanol is injected into the human body, it is rich in iodine, has a high atomic number of iodine, and has strong X-ray absorption ability, which can significantly improve the contrast between specific tissues or organs and surrounding tissues in X-ray images. In this way, doctors can use CT equipment to clearly observe structures such as blood vessels and organs, and accurately diagnose various diseases such as tumors and vascular diseases.
In angiography, iohexanol also plays an important role. Injecting it into blood vessels can clearly show the shape, course, stenosis, blockage and other conditions of blood vessels, helping doctors diagnose vascular-related diseases, such as coronary artery lesions in patients with coronary heart disease, which can be clearly shown by iohexanol angiography, providing a key basis for the formulation of follow-up treatment plans.
In addition, in urography, after iohydride is introduced into the urinary system in a specific way, structures such as the renal pelvis, calyx, ureter and bladder can be clearly developed in X-ray images, which is helpful for doctors to diagnose congenital malformations, stones, tumors and other diseases of the urinary system.
In short, 5-acetamido-N1, N3-bis (2,3-dihydroxypropyl) -2, 4, 6-triiodoisophthalamide With its excellent imaging performance, it plays a pivotal role in modern medical imaging examinations, making great contributions to the accurate diagnosis of diseases.

5 - acetamido - N1, N3 - bis (2,3 - dihydroxypropyl) - 2,4,6 - triiodoisophthalamide is also a chemical. It has several potential side effects, which are detailed below.
This substance may affect the urinary system of the human body. In some cases, it can cause increased burden on the kidneys, causing symptoms such as mild proteinuria, the appearance of protein in the urine, indicating renal filtration function or disturbance. Over time, it may impair the normal operation of the kidneys and increase the risk of renal dysfunction.
The circulatory system cannot be ignored. After use, it may cause blood pressure fluctuations, and some users may experience transient hypotension, dizziness, fatigue, etc. This is due to the action of the drug on blood vessels, causing vasodilation and lowering blood pressure. There is also a small probability of arrhythmia, cardiac rhythm disorder, affecting the heart's pumping function, and causing insufficient blood supply to the body.
Furthermore, it may irritate the immune system. After some sensitive individuals are exposed, it can trigger allergic reactions, mild skin rashes, itching unbearable; severe cases may cause respiratory edema and breathing difficulties, which is due to the immune system mistakenly recognizing the substance as a foreign harmful substance and overreacting.
The digestive system may also be implicated by it. Common side effects are nausea and vomiting, which are drugs that irritate the gastrointestinal mucosa, causing gastrointestinal peristalsis and digestive disorders. Long-term or high-dose exposure may cause more serious gastrointestinal discomfort, such as abdominal pain, diarrhea, etc., affecting nutrient absorption and overall health.
In summary, 5-acetamido-N1, N3-bis (2,3-dihydroxypropyl) -2,4,6-triiodoisophthalamide Although it has its specific uses, its side effects are diverse. Use caution and pay close attention to physical reactions to prevent adverse consequences.

5 - acetamido - N1, N3 - bis (2,3 - dihydroxypropyl) - 2,4,6 - triiodoisophthalamide, Chinese name iohexanol, is a commonly used contrast agent in clinical practice. It is suitable for a wide range of people, and listen to me one by one.
In medical examinations, this drug is often used by those who need angiography, CT enhancement scan and other imaging examinations. Because iohexanol can make blood vessels or organs appear more clearly in the image, it can assist doctors in accurate diagnosis. For example, during cerebral angiography, this drug can help doctors clearly understand the shape, course and presence of brain blood vessels, which is of great significance for the diagnosis of cerebrovascular malformations, brain aneurysms and other diseases; in enhanced CT scans, it can highlight the differences between the diseased tissue and normal tissue, making it easy to find minor lesions, which is extremely helpful for the early diagnosis of tumors.
In addition, iohexanol is also commonly used during urinary system examinations. Such as intravenous pyelography, with the help of its development in the urinary system, doctors can understand the shape and function of the kidneys, ureters and bladder, and diagnose diseases such as urinary system stones, tumors, and obstruction.
However, not everyone is suitable. For those who are allergic to iodine, it should not be used because it may cause severe allergic reactions, mild cases of rash and itching, severe cases can cause anaphylactic shock, which is life-threatening; those with serious damage to renal function should also be used with caution, because of its metabolism or increase the burden on the kidneys, which further deteriorates renal function. Pregnant and breastfeeding women also need to carefully weigh the pros and cons of medication, because the impact of the drug on the fetus or infant is not fully clear.
Overall, although iohydriol is suitable for a wide range of people, doctors must carefully evaluate the patient's condition before use to ensure that the medication is safe and effective.

5 - acetamido - N1, N3 - bis (2,3 - dihydroxypropyl) - 2,4,6 - triiodoisophthalamide iohexanol, a non-ionic contrast agent. The contraindicated groups are as follows:
1. Allergic to iohexanol or other iodine-containing contrast agents, this is a big taboo. People who cover allergies, contact with this substance, fear rapid-onset allergic reaction, mild skin itching, erythema, hives, severe cases can cause laryngeal edema, breathing difficulties, anaphylactic shock, endangering life.
2. Severe hepatic and renal insufficiency. Liver main excretion detoxification, renal excretion. Liver and kidney function are seriously impaired, unable to metabolize and excrete iohexanol normally, which can lead to drug accumulation, toxic reactions, and damage to various organs of the body.
3. Hyperthyroidism. Iohexanol contains iodine, while hyperthyroidism in patients with hyperthyroidism makes them sensitive to iodine intake. Ingestion of iodine-containing contrast agents may aggravate thyroid toxicity, causing heart palpitations, hyperhidrosis, weight loss, tremor, etc.
4. Patients with myeloma and paraglobulinemia. Such patients have an increase in abnormal proteins in the blood. After injecting iohexanol, it may affect the excretion of contrast agents, increase the risk of kidney toxicity, and abnormal proteins may interact with contrast agents, causing adverse consequences.
5. Severe cardiopulmonary insufficiency. Cardiopulmonary function is seriously insufficient, and the body's compensatory ability is poor. After the use of iohexanol, the heart load or aggravation, pulmonary circulation is also affected, which can cause breathing difficulties, heart failure and other serious complications.
6. Pregnant women and breastfeeding women. Pregnant women take drugs, drugs or through the placenta affect fetal development; breastfeeding drugs, drugs or passed to the baby through milk, pose a potential threat to the baby's health, so it is not necessary and should not be used.

5 - acetamido - N1% 2C N3 - bis% 282% 2C3 - dihydroxypropyl% 29 - 2% 2C4% 2C6 - triiodoisophthalamide is the chemical name of iohexanol. Iohexanol is a commonly used non-ionic contrast agent in clinical use, and its interaction with other drugs is quite important to physicians.
When iohexanol is used in combination with other drugs, it should be carefully observed. Covers its metabolic process in the body, or changes due to the intervention of other drugs. If used in combination with some nephrotoxic drugs, it can increase the burden on the kidneys. Kidney, the main water metabolism, detoxification of the official, nephrotoxic drugs damage its function, and iohexanol is also excreted through the kidney, the use of the two, the renal load increased sharply, or exacerbated renal damage.
Furthermore, with the use of drugs with diuretic effect, need to be reviewed in detail. Diuretics can promote the metabolism of water and change the electrolyte balance in the body, while iohexanol is distributed and excreted in the body, or affected by changes in electrolytes. Electrolytes, like messengers in the body, regulate many physiological processes, and changes in their balance can cause differences in the metabolic pathways of iohexanol.
Before using iohexanol, if the patient is using certain drugs to affect the coagulation function, it is also necessary to pay attention. During the injection of iohexanol, there may be a risk of local bleeding. The coagulation function is disturbed by other drugs, which can increase the risk of bleeding. Blood is an important substance for nourishing the body. If bleeding continues, it will damage the body.
If used in combination with central nervous system inhibitors, caution is also required. Although iohexanol is mainly used for angiography, it may have a potential impact on the nervous system. When used in combination with central nervous system inhibitors, or the inhibitory effect of the nervous system is enhanced, patients may experience drowsiness, dizziness and other diseases.
Therefore, when taking medication, physicians must carefully review the drugs used by patients, consider the interaction between iohexanol and other drugs, and weigh the pros and cons, in order to ensure the safety and effectiveness of the medication, and avoid drug-induced diseases.