What is 5 - amino - 2,4,6 - triiodo - N, N '- bis (2,3 - dihydroxypropyl) -1,3 - benzenedicarbolamide?
5-Amino-2,4,6-triiodine-N, N '-bis (2,3-dihydroxypropyl) -1,3-benzodiformamide is a rather complex organic compound. Looking at its name, it can be known that its structure contains specific atoms and groups.
"5-amino" is shown at the 5th position of the benzene ring with an amino-NH ² connection. This amino group can endow the compound with specific reactivity and properties, such as participating in various nucleophilic reactions.
"2,4,6-triiodine" indicates that there are iodine atoms attached to the 2nd, 4th, and 6th positions of the benzene ring, respectively. The iodine atoms have large atomic radius and electronegativity, which will affect the polarity, spatial structure and reactivity of the molecule. Due to the characteristics of iodine atoms, the compound may have unique performance in some specific reactions or application scenarios.
"N, N '-bis (2,3-dihydroxypropyl) " means that two 2,3-dihydroxypropyl groups are connected by nitrogen atoms. The existence of this dihydroxypropyl group makes the compound have good hydrophilicity, or affects its solubility and interaction with other substances.
"1,3-Phthalamide" determines its basic skeleton as a benzene ring, and connects formamide groups at positions 1 and 3. This structural part also contributes significantly to the stability and properties of the compound as a whole.
Such compounds may have specific uses in the fields of medicine, chemical industry, etc. In the field of medicine, or as a contrast agent due to its structural characteristics, etc., by virtue of its iodine-containing properties, it plays a role in imaging inspections; in the chemical industry, or as an intermediate for the synthesis of other complex compounds. By virtue of its polyfunctional group characteristics, it is converted into substances with different functions through various chemical reactions.
What are the main uses of 5 - amino - 2,4,6 - triiodo - N, N '- bis (2,3 - dihydroxypropyl) -1,3 - benzenedicarbolamide?
5-Amino-2,4,6-triiodine-N, N '-bis (2,3-dihydroxypropyl) -1,3-benzodiformamide, often known by its trade name iohexanol. This drug has a wide range of uses and has a significant effect in the field of medical imaging.
Iohexanol is a non-ionic contrast agent. In X-ray imaging examinations, such as angiography and urography, it can help doctors clearly observe the morphology and function of blood vessels and urinary system, so that lesions have nowhere to hide, such as vascular stenosis, urinary tract obstruction and other diseases.
In CT examination, iohexanol shines even more. After intravenous injection, it can enhance the contrast between tissues, make lesions and normal tissues more clearly distinguished, such as tumors, inflammation and other lesions, on the scan image, greatly assist doctors in accurate diagnosis.
During myelography, iohedrin is injected into the subarachnoid space, which can clearly show the morphology of the spinal cord and nerve roots, providing a key basis for the diagnosis of spinal cord lesions and nerve root diseases.
Because of its good safety, good tolerance, and relatively rare adverse reactions, it is widely used in clinical practice and is an indispensable tool for modern medical imaging diagnosis. It has made great contributions to accurate diagnosis and timely treatment of diseases.
What are the physicochemical properties of 5 - amino - 2,4,6 - triiodo - N, N '- bis (2,3 - dihydroxypropyl) -1,3 - benzenedicarbolamide?
5-Amino-2,4,6-triiodine-N, N '-bis (2,3-dihydroxypropyl) -1,3-benzodiformamide, this is an organic compound. Its physical and chemical properties are unique, let me tell you one by one.
First of all, solubility, this substance is slightly hydrophilic. Because its molecule contains multiple hydroxyl groups, the hydroxyl group is a hydrophilic group, just like the paddle of a boat, so that the molecule can "swim" in water slightly, so it has a certain solubility in water, but it is not very soluble. Because the molecule still contains iodine atoms and benzene rings and other hydrophobic parts, it hinders its smooth movement in water to a certain extent.
Besides stability, its chemical structure is relatively stable. The benzene ring has a conjugated system, which is like a strong fortress, making the molecular skeleton solid. Although amino groups and amide groups have certain reactivity, under conventional conditions, if there is no external "intrusion" such as strong acid, strong base or special oxidants and reducing agents, its structure can be maintained stable.
In terms of melting point, due to the interaction of hydrogen bonds and van der Waals forces between molecules, it is like many invisible hands pulling each other, so that the molecules are closely arranged, and high energy is required to disintegrate their lattice structure, so the melting point is quite high.
As for the appearance, it is mostly white or off-white crystalline powder under normal circumstances, delicate as frost, simple and unadorned in appearance, but it contains unique chemical mysteries and may have important uses in the fields of medicine, chemical industry, etc.
5 - amino - 2,4,6 - triiodo - N, N '- bis (2,3 - dihydroxypropyl) -1,3 - benzenedicarbolamide What are the precautions in the production process?
5-Amino-2,4,6-triiodine-N, N '-bis (2,3-dihydroxypropyl) -1,3-benzodiformamide, in the production process, there are all things that should be paid attention to.
First, the raw material is selected to be the most heavy. The quality of the raw material is directly related to the purity and properties of the product. When selecting the raw material, it is necessary to carefully check its purity and impurity content. There are many impurities, or the reaction is skewed, and the product is impure, which is hindered by subsequent application. If you choose an iodine source, you need to have high quality and purity of the iodine, so as not to cause side reactions due to impurities in the iodine, and the quality of the product will be affected.
Temperature, pH value, reaction time, etc., all affect the rate and direction of the reaction. If the temperature is too high, or the reaction is too fast, by-products will be produced; if it is too low, the reaction will be delayed and the yield will drop. With 5-amino-2,4,6-triiodine-N, N '-bis (2,3-dihydroxypropyl) -1,3-benzodiformamide, the temperature should be stable within a certain range to make the reaction smooth and smooth. The pH value is also critical. Different reaction steps may require different pH environments to promote the progress of the reaction. The reaction time should also be appropriate, the time is short, the reaction is not completed; the time is long, the energy consumption is increased, or the product is changed.
In addition, separation and purification should not be ignored. After the reaction is completed, the product is mixed in the system, containing untreated raw materials, by-products, etc. It must be separated and purified by suitable methods to obtain high-purity products. Crystallization, chromatography and other methods can be selected. According to the difference between the product and impurities, choose the most appropriate method to improve the purity of the product and meet the requirements of the application.
At the end, safety protection. During production, or involving toxic or harmful substances, the operator must follow safety regulations and wear protective clothing, such as gloves, masks, goggles, etc. The workshop also needs to be well ventilated and equipped, such as suction devices, fire extinguishing equipment, etc., to avoid accidents and ensure the safety of production.
What are the safety risks associated with 5 - amino - 2,4,6 - triiodo - N, N '- bis (2,3 - dihydroxypropyl) -1,3 - benzenedicarbolamide?
5-Amino-2,4,6-triiodine-N, N '-bis (2,3-dihydroxypropyl) -1,3-phthalamide, which involves many safety risks and needs to be treated with caution.
The first to bear the brunt is the worry of toxicity. If inadvertently ingested, inhaled or absorbed through the skin, it can endanger health. After entering the body, it may damage important organs such as liver and kidney, due to its complex chemical structure, or produce harmful intermediates during metabolism in the body, causing damage to organ cells and functional attenuation.
The second is environmental risk. Once into the environment, because of its iodine and complex organic structure, or difficult to degrade, residual accumulation in soil and water. Or affect aquatic organisms, destroy aquatic ecological balance; in soil, or inhibit crop growth, disrupt soil microbial communities.
Furthermore, fire hazards cannot be underestimated. Although not extremely flammable, it may encounter open flames, hot topics, or decompose toxic fumes, containing iodine and nitrogen oxides, etc. At the fire site, such fumes are pervasive, and inhalation is very harmful, and the fire extinguishing process is also difficult due to complex chemical properties.
Another storage risk. Specific conditions are required to avoid moisture, heat and oxidants. Humidity or high temperature can cause it to deteriorate, affecting quality and stability; contact with oxidants, or react violently, causing accidents.
In summary, 5-amino-2,4,6-triiodine-N, N '-bis (2,3-dihydroxypropyl) -1,3-benzodiformamide has many safety risks. From production to use, all links should be strictly operated in accordance with regulations to ensure personnel safety and environmental health.