5 Amino N N Bis 2 3 Dihydroxypropyl 2 4 6 Triiodo M Phthalamide
Iodobenzene

5 Amino N N Bis 2 3 Dihydroxypropyl 2 4 6 Triiodo M Phthalamide

Fengxi Chemical

Specifications

HS Code

461562

Chemical Name 5 - amino - N,N - bis - (2,3 - dihydroxypropyl)-2,4,6 - triiodo - m - phthalamide
Molecular Formula C17H22I3N3O8
Molecular Weight 821.08 g/mol
Appearance White to off - white powder
Solubility Soluble in water, slightly soluble in organic solvents
Density Approx. 2.3 g/cm³
Melting Point 193 - 197 °C
Pka Values related to acidic and basic groups in the molecule
Stability Stable under normal conditions, but sensitive to light and heat
Iodine Content High iodine content due to three iodine atoms
Chemical Name 5 - amino - N,N - bis-(2,3 - dihydroxypropyl)-2,4,6 - triiodo - m - phthalamide
Molecular Formula C11H12I3N3O8
Molecular Weight 613.94 g/mol
Appearance White to off - white powder
Solubility Soluble in water, slightly soluble in ethanol
Melting Point Approximately 190 - 194 °C
Iodine Content High iodine content (about 63.3% by mass)
Pka Has acidic and basic functional groups, multiple pKa values
Stability Stable under normal storage conditions
Odor Odorless
Chemical Formula C19H26I3N3O9
Molecular Weight 821.13
Appearance White to off - white powder
Solubility Sparingly soluble in water
Odor Odorless
Melting Point Approximately 190 - 195 °C
Ph In Solution Neutral to slightly acidic
Stability Stable under normal conditions
Hazard Class Non - hazardous in normal use
Iodine Content High iodine content due to three iodine atoms
Chemical Name 5-amino-N,N-bis-(2,3-dihydroxypropyl)-2,4,6-triiodo-m-phthalamide
Molecular Formula C18H24I3N3O8
Molecular Weight 821.01 g/mol
Appearance White to off - white powder
Solubility Soluble in water
Odor Odorless
Melting Point 190 - 195 °C
Ph Approx. 6.5 - 7.5 in solution
Stability Stable under normal conditions
Purity Typically high purity, e.g., 98%+
Packing & Storage
Packing 100 - gram bottle packaging for 5 - amino - N,N - bis - (2,3 - dihydroxypropyl)-2,4,6 - triiodo - m - phthalamide.
Storage Store 5 - amino - N,N - bis-(2,3 - dihydroxypropyl)-2,4,6 - triiodo - m - phthalamide in a cool, dry place away from direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and contamination. Avoid storing near sources of heat or reactive chemicals to maintain its stability.
Shipping 5 - amino - N,N - bis - (2,3 - dihydroxypropyl) - 2,4,6 - triiodo - m - phthalamide is shipped in specialized, sealed containers. Precautions are taken to prevent any contact with moisture or incompatible substances during transport to ensure safety.
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5-amino-n,n-bis-(2,3-dihydroxypropyl)-2,4,6-triiodo-m-phthalamide 5-amino-n,n-bis-(2,3-dihydroxypropyl)-2,4,6-triiodo-m-phthalamide 5-amino-n,n-bis-(2,3-dihydroxypropyl)-2,4,6-triiodo-m-phthalamide
General Information
Frequently Asked Questions
What is the main use of 5-amino-n, n-bis- (2,3-dihydroxypropyl) -2,4, 6-triiodo-m-phthalamide
5 - amino - N, N - bis - (2,3 - dihydroxypropyl) - 2,4,6 - triiodo - m - phthalamide is also an organic compound. Its main uses are quite extensive, mostly involving the field of medicine.
In the field of medical imaging, this compound is often used as a contrast agent. Because it contains iodine atoms, and iodine has a high atomic number, it can effectively absorb X-rays. Therefore, in many inspection items such as X-ray imaging, such as angiography, urography, etc., the compound can be introduced to make specific tissues or organs clearly developed in imaging, helping doctors to clarify their morphology and structure, so as to accurately diagnose diseases.
Taking angiography as an example, an appropriate amount of the compound is injected into the blood vessel. With its absorption properties of X-rays, the blood vessel can be clearly presented in the X-ray image, which is convenient for doctors to see whether the blood vessel is narrow, blocked, deformed and other abnormal conditions. Similarly, during urography, it can help doctors understand the morphology and function of the urinary system, such as judging whether there are stones, tumors and other lesions.
In addition, this compound may also play an important role in the diagnosis and research of some specific diseases. Due to its special chemical structure, it may interact with specific biomolecules in the body, providing a unique perspective and powerful tool for disease diagnosis and research. In conclusion, 5-amino-N, N-bis- (2,3-dihydroxypropyl) -2,4,6-triiodo-m-phthalamide has made significant contributions in the field of medical imaging diagnosis, laying a solid foundation for accurate diagnosis and follow-up treatment of diseases.
What are the side effects of 5-amino-n, n-bis- (2,3-dihydroxypropyl) -2,4, 6-triiodo-m-phthalamide
5 - amino - N, N - bis - (2,3 - dihydroxypropyl) - 2,4,6 - triiodo - m - phthalamide, the Chinese name is often iodoparol, which is an iodine contrast agent widely used in the field of medical imaging. Its side effects are mainly as follows:
- ** Allergic reaction **: This drug can cause allergic symptoms, such as skin itching, erythema, urticaria, which is caused by abnormal immune responses to the drug by the body's immune system. In severe cases, angioedema can occur, involving the face, lips and other parts. Airway edema can cause breathing difficulties and even anaphylactic shock, which is life-threatening. This is because the drug acts as a hapten and binds to proteins in the body to form a full antigen, which stimulates an excessive immune response.
- ** Cardiovascular system effects **: Some patients will have blood pressure changes, or increase or decrease after the drug is used. It may also cause arrhythmias, such as tachycardia, premature beats, etc. This is due to the direct effect of the drug on the cardiovascular system, interfering with the electrophysiological activity of the myocardium and the regulation mechanism of vascular tone.
- ** Nervous system reactions **: Some people will experience dizziness and headache, which may affect the hemodynamics of the cerebral blood vessels due to the drug, or directly stimulate the nervous system. In rare cases, it can cause convulsions, especially in patients with renal insufficiency. Drug excretion is limited, and accumulation in the body affects the
- ** Gastrointestinal Reaction **: Nausea and vomiting are more common, and are caused by drugs that stimulate the gastrointestinal mucosa or affect the gastrointestinal nerve reflex. Abdominal pain and diarrhea may also occur, interfering with the normal digestion and absorption function of the gastrointestinal tract.
- ** Kidney Toxicity **: Although relatively rare, it can cause renal impairment, especially in patients with pre-existing renal insufficiency. Drug excretion through the kidneys can affect renal tubular function and glomerular filtration rate, and in severe cases cause acute kidney injury.
What are the applicable populations of 5-amino-n, n-bis- (2,3-dihydroxypropyl) -2,4, 6-triiodo-m-phthalamide
5 - amino - N, N - bis - (2,3 - dihydroxypropyl) - 2,4,6 - triiodo - m - phthalamide is the chemical name of a drug. It is commonly used in angiography and is suitable for a wide range of people.
First, it is suitable for those who need angiography. If you want to clarify the shape, structure and blood flow of the cardiovascular system, such as the diagnosis of coronary heart disease, vascular stenosis or blockage, this drug can help the blood vessels to be clearly developed in the imaging examination, providing doctors with accurate diagnostic basis.
Second, it is suitable for those who need urography. Such as the diagnosis of urinary system stones, tumors, deformities and other lesions, the drug can make the urinary tract system show a clear outline in the image, helping the doctor to accurately judge the condition.
Third, it is suitable for some people who need to undergo CT enhanced examination. In the diagnosis and differential diagnosis of certain diseases, CT enhanced examination requires the use of contrast medium to improve the contrast between the lesion and normal tissue. This drug can play a role in this situation, helping the doctor to identify the lesion more accurately and improve the accuracy of the diagnosis.
However, it should be noted that people who are allergic to iodine or who have severely impaired kidney function should use this drug with caution. Before using the drug, the doctor must consult the patient's medical history, allergy history, etc. for safety.
What are the contraindications of 5-amino-n, n-bis- (2,3-dihydroxypropyl) -2,4, 6-triiodo-m-phthalamide
5 - amino - N, N - bis - (2,3 - dihydroxypropyl) - 2,4,6 - triiodo - m - phthalamide is iodoxanol, which is a commonly used clinical contrast agent. The main contraindications are as follows:
First, those who have a history of allergies to iodoxanol or other iodine-containing contrast agents should not be used. Because of its allergic reaction or life-threatening, such as causing severe rash, itching, breathing difficulties, and even anaphylactic shock. If you have such allergic experiences in the past, re-exposure is likely to cause more violent reactions.
Second, patients with severe hyperthyroidism are contraindicated. Iodoxanol contains iodine, which may increase the synthesis and release of thyroid hormones, aggravate the condition of hyperthyroidism, such as heart palpitations, sweating, weight loss, hand shaking and other symptoms, and even induce hyperthyroidism crisis, threatening life.
Third, severe hepatorenal insufficiency should be used with caution, or even disabled. Because the contrast agent is metabolized and excreted through the liver and kidney, when the liver and kidney insufficiency, its metabolism and excretion are blocked, easy to accumulate in the body, increase the burden on the liver and kidney, or cause further deterioration of liver and kidney damage. Severe renal insufficiency, after use or cause contrast nephropathy, causing acute kidney injury.
Fourth, pregnant and breastfeeding women should avoid use. Although there is no conclusive evidence to suggest that iodoxanol is harmful to the fetus or infant, it should not be used in these two groups of people if it is not necessary to ensure the safety of the mother and baby.
Fifth, use with caution in patients with multiple myeloma. Such patients are already vulnerable to impaired renal function, and the use of iodoxanol may increase the risk of acute renal failure.
How and how to use 5-amino-n, n-bis- (2,3-dihydroxypropyl) -2,4, 6-triiodo-m-phthalamide
5 - amino - N, N - bis - (2,3 - dihydroxypropyl) - 2,4,6 - triiodo - m - phthalamide is the chemical name of the contrast agent ioparol. It is used in medical contrast examination.
The method and dosage used vary depending on the type of examination and the patient's condition. Generally speaking, for intravenous urography, the usual dosage for adults is about 30-100ml, and the concentration is mostly 300mgI/ml or 370mgI/ml. The dosage for children is determined by weight, about 1-2ml per kilogram of body weight.
When performing angiography, such as cerebral angiography, the dosage is about 5-10ml, fine-tuned according to the vascular site and examination needs; coronary angiography, the dosage is about 4-8ml each time.
When CT enhancement scan, the usual dosage for adults is about 50-150ml, and the injection rate depends on the scanning site and equipment, usually 2-5ml per second. Children should also adjust the dosage according to their weight.
When using, pay attention to whether the patient has a history of allergies and other conditions, and closely observe the patient's reaction during injection to prevent adverse reactions. The medication should be strictly followed by the doctor and operated according to the guidelines of professional healthcare workers.