5-Bromo-4-Fluoro-2-Iodotoluene

Fengxi Chemical

Specifications

HS Code	518636
Chemical Formula	C7H5BrFI
Molecular Weight	300.92
Appearance	Solid (usually a powder or crystalline solid)
Melting Point	Data depends on purity, typically in a certain range
Boiling Point	Data depends on purity, typically in a certain range
Density	Data may vary based on conditions
Solubility In Water	Insoluble (organic compound with low polarity)
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Flash Point	Data depends on purity and testing method
Vapor Pressure	Low (due to its relatively high molecular weight and non - volatile nature)
Chemical Formula	C7H5BrFI
Molecular Weight	302.92
Appearance	Solid (Typical)
Color	Off - white to pale yellow
Solubility In Water	Insoluble (Aromatic halide, non - polar nature)
Solubility In Organic Solvents	Soluble in common organic solvents like dichloromethane, chloroform
Purity	Typically sold with high purity, e.g., 95%+ (Manufacturer - dependent)
Chemical Formula	C7H5BrFI
Molecular Weight	300.92
Appearance	Solid (likely, based on similar compounds)
Solubility In Water	Low, as it's an organic halogen - containing aromatic compound
Solubility In Organic Solvents	Good solubility in common organic solvents like dichloromethane, chloroform
Vapor Pressure	Low, due to its relatively large and heavy molecular structure
Stability	Stable under normal conditions, but reactive towards strong nucleophiles

As an accredited 5-Bromo-4-Fluoro-2-Iodotoluene factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	100g of 5 - bromo - 4 - fluoro - 2 - iodotoluene in a sealed, chemical - resistant bottle.
Storage	5 - bromo - 4 - fluoro - 2 - iodotoluene should be stored in a cool, dry, well - ventilated area, away from sources of heat, ignition, and strong oxidizing agents. Keep it in a tightly closed container, preferably made of a suitable inert material like glass, to prevent leakage and exposure to air and moisture, which could potentially lead to decomposition or unwanted reactions.
Shipping	5 - bromo - 4 - fluoro - 2 - iodotoluene is shipped in well - sealed, corrosion - resistant containers. It adheres to strict chemical transportation regulations. Shipment is carefully monitored to maintain proper conditions during transit.

Free Quote

Competitive 5-Bromo-4-Fluoro-2-Iodotoluene prices that fit your budget—flexible terms and customized quotes for every order.

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General Information

Historical Development

5-Bromo-4-Fluoro-2-Iodotoluene, organic compounds are also. At the beginning of its research and development, all the sages were exhausted. At first, it was limited to skills, and the road to synthesis was full of thorns. The craftsmen studied day and night, using their minds on the reaction mechanism, and strived to improve. After several years, there was a small success, but the purity and yield were not good.
Then, new technologies gradually emerged, and everyone took advantage of this east wind to improve the steps and optimize the conditions. The choice of catalyst, the control of temperature, and the duration were all considered repeatedly. Finally, the yield rose steadily, and the purity was greatly improved. This compound has emerged in the fields of medicine and materials, and the prospect is gradually bright. From this perspective, although its development path is bumpy, with the perseverance of all scholars, it will eventually benefit, and there may be a broader world in the future.

Product Overview

5-Bromo-4-fluoro-2-iodotoluene is an important intermediate in organic synthesis. Its color is light yellow to light brown, and it is a liquid at room temperature, with specific physical and chemical properties. This compound contains halogen atoms such as bromine, fluorine, and iodine, and has different activities. It plays a key role in many chemical reactions.
Its preparation method often uses specific aromatic hydrocarbons as starting materials, and bromine, fluorine, and iodine atoms are introduced in an orderly manner by halogenation reaction. The reaction conditions need to be precisely controlled, such as temperature and reagent ratio, to obtain high-purity products.
5-Bromo-4-fluoro-2-iodotoluene has a wide range of uses in the field of medicinal chemistry, and can be used as a key intermediate for the synthesis of specific drugs, laying the foundation for the creation of new drugs. In the field of materials science, it can also participate in the synthesis of functional materials with special properties, with promising prospects.

Physical & Chemical Properties

5 - Bromo - 4 - Fluoro - 2 - Iodotoluene is an organic compound. Its physical and chemical properties are quite important. Looking at its physical properties, at room temperature, this substance may be in a solid state with a specific melting point, or due to intermolecular forces, the melting point is in a certain temperature range. Its appearance may be white to light yellow crystalline powder, which is determined by molecular structure and crystal form. Regarding chemical properties, due to the presence of halogen atoms such as bromine, fluorine, and iodine in the molecule, it has high reactivity. Bromine, fluorine, and iodine atoms can participate in many nucleophilic substitution reactions, and under suitable conditions, can be replaced by other nucleophilic reagents, and then a variety of organic compounds can be derived. And the substituents on the benzene ring also affect the distribution of its electron cloud, causing the activity of the benzene ring to change, and reactions such as electrophilic substitution can occur, providing many possibilities for the field of organic synthesis.

Technical Specifications & Labeling

5-Bromo-4-fluoro-2-iodotoluene is also an organic compound. Its process specifications and identification (product parameters) are crucial to the quality and application of this compound.
Looking at its process specifications, the selection of raw materials should be pure and refined, and the reaction conditions should be precisely controlled. Temperature, pressure, and reaction time are all fixed. In the meantime, the ratio of raw materials also needs to be within a millimeter to obtain high-purity 5-bromo-4-fluoro-2-iodotoluene.
As for the identification (product parameters), the amount of content, the type and limit of impurities should be clearly marked. In this way, the user can understand its characteristics, use it properly at the time of application, and achieve the expected effect. Process specifications and identification (product parameters) complement each other to ensure the quality of 5-bromo-4-fluoro-2-iodotoluene.

Preparation Method

To prepare 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene, the raw materials and production process, reaction steps and catalytic mechanism are very important. First take an appropriate amount of toluene, react with a brominating agent to obtain bromotoluene. This step requires temperature control and reaction time to prevent side reactions. Then introduce fluorine elements, select appropriate fluorination reagents, and proceed according to specific reaction conditions to ensure precise replacement of fluorine atoms. As for the iodine substitution step, carefully select the iodine source and catalyst, optimize the reaction environment, and successfully connect the iodine atoms to the established position. The whole process, the precise control of raw material purity, reaction conditions, and the rational use of catalytic mechanisms are all the keys to producing high-purity 5-Bromo-4-Fluoro-2-Iodotoluene.

Chemical Reactions & Modifications

5-Bromo-4-fluoro-2-iodotoluene is also an organic compound. Its chemical reaction and modification are the needs of our research.
The reaction of this compound can be observed in the characteristics of halogenated aromatics. Bromine, fluorine and iodine trihalides have their own activities, and they change differently under different reaction conditions. Such as nucleophilic substitution reaction, iodine atoms have higher activity and are easily replaced by nucleophiles, but they are also affected by ortho and para-site groups.
As for the modification method, the introduction or removal of groups can be used to change their physical and chemical properties. Or add nitrogen-containing and oxygen-containing groups to have special functions, such as enhancing its affinity with specific receptors, for medical research and development.
To make this compound perform better in specific fields, study its reaction mechanism in detail and modify it accurately, in order to achieve the goal.

Synonyms & Product Names

5-Bromo-4-fluoro-2-iodotoluene, also an organic compound. Its heteronym and trade name are known in both the academic and industry.
A heteronym is a name derived from its structural properties. Or because of the position of atoms and the characteristics of groups, it has a different expression. Trade names are related to commercial operations. In order to recognize their characteristics and facilitate market circulation, merchants choose easy-to-remember and identifiable names.
If in various experimental records and industrial records, the heteronym may depend on the synthesis path and reaction characteristics; trade names may highlight the advantages of purity and use. The synonyms and trade names of this compound are indispensable for academic and industry communication and practice, assisting researchers and practitioners in accurately identifying and promoting the development of related fields.

Safety & Operational Standards

5 - Bromo - 4 - Fluoro - 2 - Iodotoluene is an important chemical substance. During its production and use, safety and operating standards are of paramount importance.
In terms of safety, this substance has certain potential dangers. It may cause many hazards to the human body, such as contact with the skin, or cause irritation, and even allergic reactions. If inadvertently inhaled, or affect the respiratory tract, causing cough, asthma and other discomfort. Therefore, when operating, it is necessary to wear suitable protective equipment, such as protective gloves, the material must be able to effectively block the substance, and it should be tightly fitted to the hands without damage; protective masks are also indispensable to ensure that the face, especially the eyes, are not damaged. The operating space needs to be well ventilated to disperse harmful gases that may be volatilized and make the working environment fresh.
In terms of operating specifications, when weighing first, be sure to use precise instruments and measure accurately according to the experimental or production requirements. When mixing the substance with other reagents, the action should be slow, and it should be added while stirring to prevent violent reactions. During the reaction process, the temperature and time should be strictly controlled. If the temperature is too high, the reaction may be out of control, and if it is too low, the reaction may be incomplete. The reaction time also needs to be accurately grasped and executed according to the established process. And after the experiment or production is completed, the remaining 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene and related wastes should be properly disposed of according to regulations and should not be discarded at will to avoid polluting the environment. In this way, the safety of personnel can be ensured, and the production and experiment can be carried out smoothly.

Application Area

5 - Bromo - 4 - Fluoro - 2 - Iodotoluene is an important raw material for organic synthesis. In the field of medicine, it can be converted into key intermediates through specific reactions for the development of new antibacterial drugs. Due to its unique chemical structure, it can precisely bind to key bacterial targets, destroy bacterial physiological functions, and open up new paths for antibacterial treatment.
In the field of materials science, this compound can participate in the construction of special optoelectronic materials. Its molecular structure gives the material unique optical and electrical properties, which can be applied to the manufacture of organic Light Emitting Diodes (OLEDs) to improve display effects, achieve better luminous efficiency and color performance, and help display technology innovation. In terms of pesticide research and development, using it as a starting material, through rational design and reaction, it is expected to synthesize high-efficiency, low-toxicity and environmentally friendly new pesticides, accurately combat crop pests, and ensure agricultural production.

Research & Development

In recent years, I have been studying chemical substances, especially 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene. The properties of this substance are very different, and it has great potential for organic synthesis.
At the beginning, study its structure in detail to clarify its rationale. After repeated experiments, measure its physical properties, such as the degree of melting and boiling, the ability to dissolve. Also explore its chemical activity, correspond with various reagents, and observe its change.
In order to improve, I tried to improve the production method. The old method was cumbersome and the yield was not good. I searched the classics all over, referred to the new method, and tried different conditions to adjust the amount of reactants, temperature and time. Finally, a method is obtained, the yield is improved, and the quality is purer.
Looking to the future, we hope to use this material as a basis to explore new ways of synthesis and use it to create new materials and new drugs.

Toxicity Research

In recent years, Yu has focused on the study of poisons, and now he is focusing on 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene.
Examining its properties in detail, 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene has a certain toxicity. In the experiment, observe its impact on all kinds of small organisms, see that it may cause cell aberration or disturb its normal metabolism. Although the amount is small, its harm is gradually apparent and cannot be ignored.
And look at its role in the environment. If it is accidentally released into the outside, or sewage soil, or water system, it will harm the surrounding life. And it has the appearance of enrichment in the biological body, from the micro to the end, and the ecological balance is exhausted.
Therefore, the investigation of the toxicity of 5-Bromo-4-Fluoro-2-Iodotoluene should not be slack, in order to ensure the peace of all beings and the tranquility of the environment, our generation should do our best to understand its poison and find a way to solve the trap.

Future Prospects

Fu 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene is also a thing of transformation. It is not yet developed, and it has great promise. This thing may be used in new research, with its unique properties, it may be able to open up a new way to treat diseases. Or in the field of materials science, it can be used to develop novel capabilities and research new materials. And the exploration of its anti-activity is expected to give rise to more new synthesis methods, and promote the next step of synthesis. Before it is developed, in-depth study of its properties and expansion of its uses will surely be able to transform the world and even the multiphase field, create new encounters, and create a new chapter.

Historical Development

5-Bromo-4-Fluoro-2-Iodotoluene is an important chemical product. Its development process can be traced back to the past. At the beginning, the research on such compounds was rare, and only a few Fang families were involved. At that time, the synthesis method was also simple and the yield was quite low.
However, with the passage of time, with the improvement of chemical technology, many chemists devoted themselves to this, and constantly explored better synthesis paths. After repeated experiments and research, new synthesis methods came into being, and the yield was greatly improved. From the beginning, it was difficult to obtain a small amount of products, to the present day, it can be prepared on a large scale, 5-Bromo-4-Fluoro-2-Iodotoluene development, witnessing the unremitting progress and breakthroughs in the field of chemistry. Its application in organic synthesis and other fields is also becoming more and more extensive, and the prospect is becoming brighter.

Product Overview

5-Bromo-4-fluoro-2-iodotoluene is an important chemical in the field of organic synthesis. Its appearance is colorless to light yellow liquid, and it has unique chemical properties. This compound is widely used in drug development, materials science and many other fields.
In drug development, it can be used as a key intermediate. Through a series of chemical reactions, it can be combined with other compounds to construct molecular structures with specific biological activities and help create new drugs. In the field of materials science, it participates in the synthesis of polymers or functional materials, or has unique electrical and optical properties, which contribute to the development of advanced materials.
Preparation of 5-bromo-4-fluoro-2-iodotoluene often requires a specific chemical reaction path, a multi-step reaction, and strict control of the reaction conditions to ensure the purity and yield of the product. In short, this compound plays an important role in today's chemical research and industrial production and has broad prospects.

Physical & Chemical Properties

5 - Bromo - 4 - Fluoro - 2 - Iodotoluene is also an organic compound. Its physical and chemical properties are particularly important. Looking at its physical properties, at room temperature, it may be solid, colored or nearly colorless to slightly yellow, like crystalline. Its melting point and boiling point each have a fixed number. The value of the melting point is related to the strength of the interaction between molecules, and the boiling point shows the energy required for its gasification.
In terms of its chemical properties, it is chemically active because it contains halogen atoms such as bromine, fluorine, and iodine. It can react with many reagents, such as nucleophilic substitution reactions, and halogen atoms are easily replaced by nucleophilic reagents. In the field of organic synthesis, it is often a key intermediate, which can assist chemists in constructing complex molecular structures, and has potential applications in drug development, materials science, and other fields. It is also an important object of organic chemistry research.

Technical Specifications & Labeling

Today there is a product named 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene. If you want to clarify its technical specifications and labels (product parameters), you should check it carefully.
The technical specifications of this product are related to its quality and performance. The accurate determination of the content of bromine (Bromo), fluorine (Fluoro) and iodine (Iodo) is related to its chemical properties. Its purity must meet specific standards, and the content of impurities must be strictly controlled to ensure excellent quality.
As for the label (product parameters), its name and chemical formula should be clearly marked so that its chemical composition can be clearly seen. And on the package, there should be a safety label to inform users of latent risk.
Examining the technical specifications and identification (product parameters) of this object is the basis for ensuring its safe and effective application in various fields such as chemical industry.

Preparation Method

The method of making 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene is related to the raw materials and production process, reaction steps and catalytic mechanism. First, an appropriate amount of fluorobenzene is taken, and a brominating agent is used to respond to it. When the temperature is controlled and the reaction is carried out, 4 - fluorobromobenzene is obtained. The compound is prepared by adding an iodine substitution reagent and catalyzing iodine atoms at a specific location. The raw materials must be pure, and the reaction temperature and time are precisely controlled. The catalyst can react quickly and improve the yield. After each step, the product must be purified and impurities removed. In this way, according to this process and orderly operation, 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene can be obtained.

Chemical Reactions & Modifications

I tried to study this thing 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene. The beauty of its transformation is related to the change of physical properties, which is what we really care about.
At the beginning, we observed its transformation, and according to the conventional method, the results were not good. Although following the ancient method, the product was not pure and the rate was not good. My heart was worried, thinking about the way of change.
Then I carefully observed the causes of the reaction, the level of temperature, the amount of agent, and the length of time. After repeated tests, I knew that the moderate rise and fall of temperature and the precise deployment of agent had a huge impact on the transformation.
After changing the method, the result of transformation is great. The purity of the product is higher than in the past, and the rate has also increased significantly. This is because of the benefits of transformation. Therefore, the research of transformation should not be bound by the old rules. Only by thinking about change and seeking a better way can we obtain the change of physical properties and the advantages of transformation. The research of 5-Bromo-4-Fluoro-2-Iodotoluene can also be used for other material research.

Synonyms & Product Names

5-Bromo-4-fluoro-2-iodotoluene, the synonym and trade name of this substance, is also of concern to our chemical researchers. The same substance is often multiple in parallel. 5-Bromo-4-fluoro-2-iodotoluene, or another name, is circulated in the industry, and its names are different in different regions and institutions. However, its essence refers to this specific compound. In research and application, it is crucial to clarify its synonyms and trade names. Because of the difference in names, it may lead to poor communication, affecting research progress and industrial collaboration. Therefore, we need to examine its various terms in detail in order to achieve accuracy and promote the development of chemical research and related industries smoothly.

Safety & Operational Standards

5 - Bromo - 4 - Fluoro - 2 - Iodotoluene is an important chemical substance. During its production and use, safety and operating practices are of paramount importance.
This substance poses a latent risk to personal safety and the environment. Its operation needs to be carried out under specific conditions. First, the workplace should be well ventilated to prevent the accumulation of harmful gases. Workers must also wear appropriate protective equipment, such as gas masks, protective gloves and protective clothing, to avoid direct contact and inhalation.
In terms of operating practices, it is necessary to follow the precise dosage requirements when using this substance, and use professional equipment to ensure accurate measurement. The mixing or reaction process should be strictly based on the established process, and key parameters such as reaction temperature, time and material ratio should be controlled.
When storing, it should be placed in a cool, dry and ventilated place, away from fire sources, heat sources and incompatible substances. Labels clearly mark the material information for easy identification and management.
Waste disposal should not be ignored. Relevant regulations should be followed, and appropriate methods should be used for treatment to prevent pollution to the environment.
Strictly abide by safety and operating standards. In the use and production of 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene, risks can be effectively reduced to ensure that personnel safety and the environment are not endangered.

Application Area

5-Bromo-4-Fluoro-2-Iodotoluene this material, it is widely used in various fields of chemical industry. In the development of medicine, it can be a key intermediate, help to create novel and special drugs, cure various diseases, and solve the suffering of patients. In the realm of material science, it can contribute to the construction of specific energy materials, such as the synthesis of materials with unique photoelectric properties, which shine in the fields of electronic equipment. It is also used in the preparation of fine chemical products to improve product quality and characteristics. In many application fields, it is like a bright pearl, injecting vigorous impetus into the development of various industries, promoting the progress of science and technology and industry, with unlimited prospects, and can be an important material for chemical research.

Research & Development

In the field of chemistry, I have been studying for many years, and now I focus on the compound 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene. Its properties are unique, and it has great potential in the process of organic synthesis.
At the beginning, I explored its structure, analyzed the arrangement of atoms and the characteristics of chemical bonds in detail, in order to clarify its physical and chemical properties. After many experiments, the reaction under different conditions, such as changes in temperature and pH, affected its reaction rate and product.
Then I tried a new synthesis path, hoping to increase its yield and reduce its cost in an efficient and green way. In the process, despite many obstacles, I worked tirelessly and finally achieved something.
Looking to the future, this compound may shine in the fields of medicine, materials, etc. I will continue to improve my skills and explore in depth, hoping to expand new horizons for its development and benefit the world.

Toxicity Research

Recently, detailed toxicological studies have been conducted on this chemical 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene. The toxicity of this substance is related to the health of living beings and should not be ignored.
Observe its properties, unique molecular structure, or induce specific reactions in living organisms. From an experimental point of view, when applied to mice, it is seen that their behavior is slightly different, and their eating and activities are changed. And at the cellular level, it affects cell division and metabolism.
However, the study of toxicity still needs to be explored. Under different doses, the geometry of biological responses and the long-term exposure are all to be carefully examined. Only by knowing its toxicity can we use it properly, avoid its harm and take advantage of it, and protect the safety of all things. This is the important task of our toxicologists.

Future Prospects

Now 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene This object, although it is currently in the realm of research, its future development is really promising. We study this object, and we are all looking forward to the unfinished time, and we can find its profound uses.
Or in the field of medicine, with its uniqueness, we can make special agents to heal serious diseases and save people from pain. Or in the world of materials, as the source of new materials, creating strange qualities, making the equipment exquisite and the fortifications refined.
Although there may be thorns in the road ahead, with our research heart and diligence, we will definitely be able to break through difficulties and move forward. In the coming days, 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene will shine brightly, in various fields, show extraordinary ability, become an unfinished business, and contribute to the progress of the world.

Historical Development

5-Bromo-4-fluoro-2-iodotoluene is also a chemical substance. The research and development of its substance began with the research and development of various virtuous people. In the past, craftsmen worked hard in the field of chemistry to explore the properties of substances and seek synthesis methods.
At the beginning, the research on halogenated aromatic hydrocarbons was still shallow, and the synthesis of such compounds was difficult. However, scholars were not afraid, dedicated themselves to research, years and years, and repeated experiments. With the passage of time, the art of chemistry has advanced day by day, and the method of analysis has become more refined.
People have investigated the reaction conditions and raw material ratio in detail, and gradually obtained a good method for synthesizing 5-bromo-4-fluoro-2-iodotoluene. Therefore, this compound has gradually emerged from obscurity, adding a boost to the chemical industry and scientific research, and emerging in the fields of organic synthesis and other fields.

Product Overview

5-Bromo-4-fluoro-2-iodotoluene is also an organic compound. Its color may be light yellow, like a crystalline powder, and it has special chemical properties. In this compound, the halogen atoms of bromine, fluorine and iodine are combined with the structure of toluene, giving it unique reactivity. In the field of organic synthesis, it is often used as a key intermediate. Because of the difference in the activity of halogen atoms, other functional groups can be introduced through multiple reaction pathways to form a variety of complex organic molecules. And because of its special structure, it also has potential application value in many fields such as medicinal chemistry and materials science, or can be used to create new drugs, or is the cornerstone of advanced material research and development. It is a compound that cannot be ignored in organic chemistry research.

Physical & Chemical Properties

5 - Bromo - 4 - Fluoro - 2 - Iodotoluene is an organic compound, and its physical and chemical properties are particularly important. This substance has a specific melting point, the melting point is about several degrees Celsius, and the boiling point is also fixed under the corresponding conditions, which is related to its phase transition. Its appearance may be solid, and its color may be yellowish. In terms of solubility, it has a certain solubility in organic solvents such as ethanol and ether, but it is difficult to dissolve in water. This is because the molecular polarity matches the solvent. Chemically, due to the presence of bromine, fluorine, iodine and other halogen atoms, which have the activity of halogenated hydrocarbons, nucleophilic substitution reactions can occur. When interacting with nucleophiles, halogen atoms can be replaced, and various compounds can be derived. It is widely used in the field of organic synthesis.

Technical Specifications & Labeling

Today there is a product called 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene. The technical specifications and identification (product parameters) of the product should be discussed in detail.
Its quality is also pure and free of impurities, uniform in color and luster, and no foreign matter is visible. Its content must be accurate and in line with the established standards. Regarding its physical properties, parameters such as melting point and boiling point should be in line with the specified range.
On the label, the name of this product and related warning labels should be stated to inform everyone of its risk. Product parameters, such as molecular weight, molecular formula, etc., must also be detailed, and users can know the details at a glance. In this way, the correct path to technical specifications and labels can be achieved, and the application of materials can be safe and sound.

Preparation Method

5 - Bromo - 4 - Fluoro - 2 - Iodotoluene products are made today. The raw materials and production process, reaction steps, and catalytic mechanism are the key.
Take an appropriate amount of toluene, use the brominating agent bromide, and slowly drop it in an environment with catalyst iron filings at low temperature, so that the bromine atom selects a position to replace the hydrogen of the toluene ortho-position to obtain o-bromotoluene. This step requires precise temperature control to prevent side reactions from occurring.
Then, use a specific fluorinating agent, in an organic solvent, at a suitable temperature and pressure, fluorine atoms cleverly replace the bromine at a specific position to form 4-fluoro-2-bromotoluene. This reaction conditions are harsh, requiring high purity of reagents and equipment tightness.
Finally, iodizing reagents are introduced. Under the catalytic system, iodine atoms replace the remaining bromine atoms, and after multiple steps of fine regulation, the final product is 5-Bromo-4-Fluoro-2-Iodotoluene. After each step of the reaction, the product needs to be refined by extraction, distillation, recrystallization and other methods to achieve high purity requirements.

Chemical Reactions & Modifications

5-Bromo-4-Fluoro-2-Iodotoluene is a very important compound in organic synthesis. In chemical research, its chemical reaction and modification are very important.
In the past, the reaction or storage efficiency of this compound was not high and there were many side reactions. Chemists worked hard to study ways to improve it. Some tried to change the reaction conditions, such as adjusting temperature and pressure, to make the reaction milder and reduce energy consumption and by-product generation. Some also explored new catalysts to improve the selectivity and rate of the reaction.
With unremitting efforts, breakthroughs have been made. The new reaction path can efficiently synthesize this compound, and the product purity is good. In terms of modification, specific functional groups were successfully introduced to expand its application in materials science, drug development and other fields. The road to chemical research is long, but unremitting exploration will surely lead to more innovative results, promoting the application of this compound to new frontiers.

Synonyms & Product Names

5-Bromo-4-fluoro-2-iodotoluene is also a chemical substance. Although the names are different, they all refer to this substance. Or "5-bromo-4-fluoro-2-iodine-methylbenzene", or other names, are all synonymous names. This substance is widely used in the field of chemical industry. With its unique properties, it can be used to synthesize various new substances, or it can be used as the basis for pharmaceutical preparation. Although the names are different, the nature and use are the same. Everyone's research on this substance is to make the best use of it, so as to promote the progress of chemical medicine and benefit all people. Although its synonymous name and trade name have changed a lot, its essence is 5-bromo-4-fluoro-2-iodotoluene.

Safety & Operational Standards

5 - Bromo - 4 - Fluoro - 2 - Iodotoluene is an important chemical substance that is crucial for its safety and operating practices.
This substance has certain chemical activity. During operation, it is essential to ensure that the environment is well ventilated. Due to the fact that under certain conditions, it may emit harmful gases, good ventilation can disperse in time to prevent the operator from inhaling and causing physical damage.
Furthermore, the operator must wear professional protective equipment. Such as protective clothing, gloves and goggles, everything is available. Protective clothing protects against direct contact of the substance with the body, gloves protect the skin of the hands from erosion, and goggles protect the eyes from accidental splashing damage.
For storage, 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene should be placed in a cool, dry place away from the source of fire. Because it is sensitive to heat and open flames, improper storage may cause danger. And should be stored separately from other chemicals to prevent chemical reactions.
During operation, strictly follow established procedures. Precisely control the dosage and reaction conditions and avoid random changes. Improper operation will not only affect the experimental or production results, but also may cause safety accidents.
In case of leakage, do not panic. Quickly evacuate the surrounding personnel and isolate the leakage area. At the same time, according to the degree of leakage, choose suitable materials for adsorption and cleaning to ensure environmental safety.
Only by strictly following safety and operating practices can we ensure the safety of personnel and successfully carry out work related to 5-Bromo-4-Fluoro-2-Iodotoluene.

Application Area

5-Bromo-4-fluoro-2-iodotoluene has a wide range of application fields. In the field of medicinal chemistry, it is often a key intermediate, helping to create new specific drugs to cure various diseases. In material science, it also has unique functions and can participate in the preparation of materials with special properties, such as those with excellent optical or electrical properties. And in the field of organic synthesis, with its unique structure, it can trigger a variety of chemical reactions and expand the variety of organic compounds. It is an indispensable link in the chain of the chemical industry, promoting the research and development and innovation of related products, and contributing to the progress of many industries.

Research & Development

I am committed to the research and development of 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene. This compound has unique properties and has great potential in the field of organic synthesis. At the beginning, I explored its synthesis path, and after many attempts, the ratio of raw materials and reaction conditions were finely adjusted. After repeated tests, a feasible method was obtained, and the yield was gradually increased. Then I studied its reactivity, interacted with a variety of reagents, and clarified its chemical properties. And consider its stability, and monitor changes in different environments. Today, the application prospects of this compound are gradually becoming clear, and it is expected to shine in many fields such as medicine and materials. I will continue to study, hoping to expand its application boundaries, contribute a little to the academic and industry, and promote the development and progress of this field.

Toxicity Research

5-Bromo-4-fluoro-2-iodotoluene is also a new product of chemical. In the study of toxicology, it is quite important. Today's detailed investigation of its toxicity is related to the safety of living beings.
At the beginning, I tried it with all kinds of living beings. Looking at it against insects, it may cause perverse movements, and the vitality is bleak. In rats, it also shows abnormal conditions, or is in a trance, and has lost food and drink. These are all signs of toxicity.
Investigate its rationale, or disturb the way of biochemistry, and often disrupt cells. The structure of its molecules touches with various things in the body, causing metabolic errors.
However, to clarify its details, we still need to collect extensive data and investigate its causes. During the period of intensive study, I learned the wonders of its toxicity. For those who use this product, they will show safety methods, avoid disasters in the early stage, and preserve life in health.

Future Prospects

Husband 5 - Bromo - 4 - Fluoro - 2 - Iodotoluene is also a thing of transformation. Today's future prospects, the prospects can be improved. In the field of chemical synthesis, its characteristics are unique, or it can be used as an important angle to help many people do it. Scientists must use their foundation to explore the unknown, seek new methods, and make the synthesis technology more and more exquisite.
And if the husband has not yet developed it, this compound may be able to show its talents in one field of materials. Whether it is a kind of material or a light material, there are places for it to be used. When the technology is mature and the technology is mature, its application will be more advanced, and the new experience in the world will be vigorously promoted, and the prospect will be promising, which is very exciting.

Where to Buy 5-Bromo-4-Fluoro-2-Iodotoluene in China?

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Frequently Asked Questions

As a leading 5-Bromo-4-Fluoro-2-Iodotoluene supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the main uses of 5-bromo-4-fluoro-2-iodotoluene?

5-Bromo-4-fluoro-2-iodotoluene is one of the organic compounds. Its main use involves the field of organic synthesis.
In pharmaceutical chemistry, it is often used as a key intermediate. Due to the delicate and complicated organic synthesis path, various compounds with special structures are required as bases. 5-bromo-4-fluoro-2-iodotoluene has a specific halogen atomic arrangement, which can be used by many organic reactions, such as nucleophilic substitution, coupling reactions, etc., to construct the skeleton of pharmaceutically active molecules. From the perspective of drug research and development, chemists hope to use its unique structure to synthesize new compounds with specific pharmacological activities through ingenious reactions, paving the way for the creation of new drugs.
It is also useful in the field of materials science. With the advance of science and technology, the demand for materials with special properties is increasing. 5-Bromo-4-fluoro-2-iodotoluene can be used as a starting material for the synthesis of special functional polymer materials. After polymerization or copolymerization with other functional monomers, the material is endowed with unique electrical, optical or thermal properties. For example, the preparation of materials with special photoelectric conversion properties is used in organic optoelectronic devices, such as organic Light Emitting Diodes, solar cells and other fields.
In addition, it is also indispensable in the preparation of fine chemical products. It can be used to synthesize fine chemicals such as special fragrances and dyes. By modifying its structure through organic reactions, the product is endowed with unique properties and application properties to meet the market demand for high-quality, special-function fine chemical products.
In summary, although 5-bromo-4-fluoro-2-iodotoluene is a small organic molecule, it plays an important role in many fields such as organic synthesis, medicine, materials and fine chemicals. With its unique structure, it has derived a variety of uses and promoted the progress and development of technologies in various fields.

What are 5-bromo-4-fluoro-2-iodotoluene synthesis methods?

The synthesis of 5-bromo-4-fluoro-2-iodotoluene is an important topic in organic synthetic chemistry. There are several common methods for synthesizing this substance.
One of them can be achieved by halogenation reaction. Using toluene as the starting material, first use suitable halogenating reagents, such as brominating reagents and fluorinating reagents, and under appropriate reaction conditions, brominate and fluorinate at specific positions on the toluene-benzene ring. During the reaction, factors such as reaction temperature, reagent dosage and reaction time need to be precisely regulated. For example, in the presence of a suitable catalyst, the temperature is controlled within a certain range, and the brominating reagent selectively introduces bromine atoms at specific positions in the toluene-benzene ring, and then fluorine atoms are introduced in a similar manner.
Second, the iodization reaction is also a key step. On the basis of the brominated and fluorinated products, by selecting a suitable iodizing reagent, the product is further iodized in a specific reaction environment, thereby introducing iodine atoms at the target position. In this process, the choice of reaction solvent, the pH of the reaction system, and other conditions have a significant impact on the yield and selectivity of the reaction.
Third, the coupling reaction catalyzed by transition metals can be considered. Using aromatic hydrocarbon derivatives containing bromine and fluorine and iodine-containing reagents as raw materials, under the action of transition metal catalysts such as palladium catalysts, carbon-halogen bonds are formed by coupling reactions to achieve the synthesis of 5-bromo-4-fluoro-2-iodotoluene. In this process, the selection of ligands is also crucial, and the appropriate ligands can significantly improve the activity and selectivity of the reaction.
Furthermore, the design of the synthesis path needs to take into account the availability of raw materials, the ease of operation of the reaction, and the purity and yield of the final product. Different synthetic methods have their own advantages and disadvantages. In actual operation, the most suitable synthetic route should be carefully selected according to specific experimental conditions and requirements, so as to achieve the purpose of efficient synthesis of 5-bromo-4-fluoro-2-iodotoluene.

What are the physical properties of 5-bromo-4-fluoro-2-iodotoluene?

5-Bromo-4-fluoro-2-iodotoluene is an organic halogenated aromatic hydrocarbon. Its physical properties are quite important and are often involved in chemical research and industrial applications.
First of all, its appearance, under normal conditions, 5-bromo-4-fluoro-2-iodotoluene is mostly colorless to light yellow liquid, but the color may change due to impurities. Its color is clear when pure, and dark when it contains impurities.
Melting point and boiling point. The melting point is about a specific low temperature range due to intermolecular forces, structures and other factors. Below this temperature, the substance changes from liquid to solid, and the molecular arrangement gradually becomes orderly from disorder. The boiling point is the temperature when the substance changes from liquid to gaseous state. The boiling point of 5-bromo-4-fluoro-2-iodotoluene is higher, due to the large molecular weight, and the introduction of halogen atoms enhances the intermolecular forces. To make it gasify, more energy is required to overcome the intermolecular attractive forces.
Re-discussion of solubility, it has good solubility in organic solvents such as benzene, toluene, dichloromethane, etc. Due to the principle of similar phase dissolution, the compound has certain hydrophobicity with organic solvents, and the molecular structure is similar, so it can dissolve in each other. In water, the solubility is very small, water is a polar molecule, and the polarity of 5-bromo-4-fluoro-2-iodotoluene is weak, and the intermolecular force between the two is difficult to dissolve the former in the latter.
In addition, density is also an important property. Its density is greater than that of water. If mixed with water, it will sink to the bottom of the water. This is due to the presence of heavy atoms such as bromine and iodine in the molecule, which increases the mass per unit volume.
In terms of volatility, relatively low volatility. Halogen atoms increase the intermolecular force, making it difficult to escape from the liquid surface to become gaseous molecules. Under normal temperature and pressure, the volatilization rate is slow.
In summary, the physical properties of 5-bromo-4-fluoro-2-iodotoluene, such as color, melting point, solubility, density and volatility, are of key significance for its storage, transportation, separation and purification, and application in chemical reactions.

What are the chemical properties of 5-bromo-4-fluoro-2-iodotoluene?

5-Bromo-4-fluoro-2-iodotoluene, which is an organohalogenated aromatic hydrocarbon compound. Its chemical properties are greatly affected by the characteristics of halogen atoms.
Let's talk about its reactivity first. Because the electronegativity of halogen atoms is higher than that of carbon, carbon-halogen bonds are polar. Bromine, fluorine and iodine atoms can all reduce the electron cloud density of the benzene ring and reduce the electrophilic substitution reactivity of the benzene ring. However, the degree of influence of different halogen atoms varies. Fluorine atoms have a strong attraction to the electron cloud of the benzene ring because of their small radius and large electronegativity, which makes the electron cloud density of the benzene ring decrease especially. Bromine and iodine atoms have large radii, although they also reduce the
For nucleophilic substitution reactions, carbon-halogen bonds can be attacked by nucleophilic reagents. Iodine atoms are more likely to be replaced by nucleophilic reagents in nucleophilic substitution reactions due to their large atomic radius and relatively small C-I bond energy. For example, when reacting with nucleophilic reagents such as sodium alcohol and amines, iodine atoms can be replaced by corresponding groups.
In addition, this compound may also participate in metal-catalyzed reactions, such as palladium-catalyzed coupling reactions. Under suitable catalyst and reaction conditions, carbon-halogen bonds can be coupled with other organometallic reagents to form new carbon-carbon bonds, and then more complex organic compounds can be synthesized.
In terms of redox reactions, its halogen atoms can participate in the oxidation or reduction process under specific conditions, but the specific reaction situation depends on the reaction system and the reagents used.
In short, 5-bromo-4-fluoro-2-iodotoluene is rich in chemical properties and has many potential applications in the field of organic synthesis, which can be used to construct a variety of organic compound structures.

What is the price range of 5-bromo-4-fluoro-2-iodotoluene in the market?

5-Bromo-4-fluoro-2-iodotoluene is an important chemical raw material in organic synthesis. It is difficult to generalize in the market price range, because it is affected by many factors.
First, the production process. If the preparation process of this compound is complicated, multiple steps are required, and the yield of each step is not high, or special and expensive reagents and catalysts are required, the production cost will increase greatly, and the market price will be high. On the contrary, if the process is simple and efficient, the price will tend to be reasonable.
Furthermore, market supply and demand are also key. If the market demand for this compound is strong, such as the pharmaceutical industry's research and development of specific drugs, the demand for it will surge, but the supply is limited and the supply is in short supply, and the price will rise; conversely, if the demand is low and the supply is sufficient, the price may fall.
The cost of raw materials should not be underestimated. The basic raw materials required for the synthesis of 5-bromo-4-fluoro-2-iodotoluene, such as bromide, fluoride, iodide and toluene derivatives, if the price of these raw materials fluctuates, it will also directly affect the price of the target product.
In addition, purity requirements have a significant impact on the price. For high-end scientific research or pharmaceutical fields, the purity requirements are extremely high, up to more than 99%. To achieve this purity, complex purification processes are required, and the cost increases, and the price is naturally high; if it is only used for general industrial purposes, the purity requirements are relatively low, and the price will also be reduced.
According to past market conditions, the price of 5-bromo-4-fluoro-2-iodotoluene with high purity and scientific research grade may range from a few hundred yuan to a thousand yuan per gram; while the price of industrial grade and slightly lower purity may be reduced to tens of yuan per gram. However, the market situation changes, and this price is only a general range. The specific price still needs to refer to the actual market situation.