5 Chloro 2 Iodophenol
Iodobenzene

5 Chloro 2 Iodophenol

Fengxi Chemical

Specifications

HS Code

572087

Name 5-chloro-2-iodophenol
Molecular Formula C6H4ClIO
Molecular Weight 256.45
Appearance Solid (likely white to off - white)
Melting Point Data needed
Boiling Point Data needed
Density Data needed
Solubility In Water Low solubility, likely sparingly soluble
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone
Flash Point Data needed
Pka Data needed
Chemical Category Halo - substituted phenol
Chemical Formula C6H4ClIO
Molar Mass 256.45 g/mol
Appearance Solid (presumably, based on similar compounds)
Physical State At Room Temperature Solid
Solubility In Water Low, due to non - polar benzene ring and hydrophobic halogen atoms
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, acetone, etc., due to non - polar nature
Chemical Formula C6H4ClIO
Molecular Weight 256.45
Appearance Solid (predicted)
Boiling Point Estimated around 270 - 280 °C
Solubility In Water Low solubility (organic compound with polar - non - polar balance favoring non - polar solvents)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether, etc.
Density Estimated based on related compounds, around 2.0 - 2.2 g/cm³
Pka Related phenols have pKa around 9 - 10, this might be in a similar range
Flash Point Estimated to be relatively high, above 100 °C (flammability hazard considered)
Chemical Formula C6H4ClIO
Molar Mass 256.45 g/mol
Appearance Solid (predicted from similar compounds)
Solubility In Water Low (due to non - polar aromatic structure)
Solubility In Organic Solvents Soluble in common organic solvents like ethanol, ether
Vapor Pressure Low (estimated from molecular structure and volatility of similar compounds)
Packing & Storage
Packing 5 - chloro - 2 - iodophenol in 100g bottles, well - sealed for chemical storage.
Storage 5 - Chloro - 2 - iodophenol should be stored in a cool, dry, well - ventilated area, away from heat sources and open flames. It should be kept in a tightly sealed container to prevent exposure to air and moisture, which could potentially lead to degradation. Store it separately from incompatible substances like strong oxidizing agents and bases to avoid chemical reactions.
Shipping 5 - Chloro - 2 - iodophenol, a chemical, should be shipped in well - sealed, corrosion - resistant containers. Label it clearly as a chemical substance. Ensure compliance with hazardous material shipping regulations to prevent leaks and ensure safe transit.
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5-chloro-2-iodophenol 5-chloro-2-iodophenol 5-chloro-2-iodophenol
General Information
Frequently Asked Questions
What is the chemistry of 5-chloro-2-iodophenol?
5-Chloro-2-iodophenol, this is an organic compound. Its physical properties, at room temperature or as a solid, have a specific melting point and boiling point, but the exact value needs to be determined by experiment. Looking at its appearance, it may be white to light yellow crystalline powder, smell it, or have a special smell.
As for chemical properties, the phenolic hydroxyl group is an active functional group, acidic, and can react with bases to form corresponding phenolic salts. For example, when it encounters a solution of sodium hydroxide, 5-chloro-2-iodophenol sodium and water will be formed.
Furthermore, the electron cloud density distribution changes due to the substitution of chlorine and iodine atoms on the benzene ring. Chlorine and iodine atoms are electron-withdrawing groups, which reduce the electron cloud density of the benzene ring and reduce the activity of the electrophilic substitution reaction of the benzene ring. However, under appropriate conditions, electrophilic substitution reactions can still occur, such as halogenation, nitrification, etc.
Because of its iodine atoms, iodine atoms have certain reactivity. Under specific reagents and conditions, substitution reactions can occur, and iodine atoms may be replaced by other functional groups.
In addition, the compound may also participate in redox reactions, and phenolic hydroxyl groups are easily oxidized to form oxidation products such as quinones. In the field of organic synthesis, 5-chloro-2-iodophenol can be used as an intermediate. After a series of reactions, organic compounds with more complex
What are the main uses of 5-chloro-2-iodophenol?
5-Chloro-2-iodophenol is also an organic compound. It has a wide range of uses and is used in various fields.
Bearing the brunt, in the field of pharmaceutical chemistry, 5-chloro-2-iodophenol is often a key intermediate for the synthesis of drugs. Because of its specific chemical structure, it can react with other compounds to build drug active ingredients. For example, through a series of chemical transformations, it can be introduced into the complex drug molecular structure to increase the specificity and targeting of drugs, and then improve the efficacy of drugs. It may play an important role in the synthesis of antibacterial and antiviral drugs, or it may endow the drugs with unique antibacterial and antiviral effects.
Furthermore, in the field of materials science, this compound is also useful. Due to its structure containing chlorine and iodine atoms, it is endowed with special physical and chemical properties. In the synthesis of some polymer materials, adding 5-chloro-2-iodophenol may improve the properties of the material. For example, it may enhance the chemical resistance of the material, so that it can remain stable in harsh chemical environments; or it can improve the optical properties of the material, such as for photochromic materials, so that it presents different optical responses under different light conditions.
In the field of agriculture, 5-chloro-2-iodophenol also has potential uses. Because it has certain biological activities, it may be developed as a new type of pesticide raw material. After appropriate chemical modification, highly efficient, low-toxic and environmentally friendly pesticides can be prepared to control crop diseases and pests, ensure crop growth and improve agricultural yield.
In addition, in the study of organic synthetic chemistry, 5-chloro-2-iodophenol is often used as an important reagent. Chemists use it to explore and study various organic reactions, such as nucleophilic substitution, coupling reactions, etc. Through these reactions, diverse organic molecular structures can be constructed, providing the basis and possibility for the development of organic synthetic chemistry.
What is 5-chloro-2-iodophenol synthesis method?
5-Chloro-2-iodophenol is also an organic compound. The method of its synthesis can be described in detail.
2-iodophenol is often used as the starting material to react with chlorine-containing reagents. For example, chlorination agents such as N-chlorosuccinimide (NCS) can be selected. This chlorination agent can introduce chlorine atoms into the molecular structure of 2-iodophenol in a suitable reaction environment.
During the reaction, 2-iodophenol is mostly dissolved in suitable solvents, such as dichloromethane and other inert solvents. These solvents can dissolve the reactants without interfering with the reaction system. N-chlorosuccinimide is slowly added to the solution containing 2-iodophenol, and at the same time, a suitable catalyst can be added to promote the reaction. The temperature of the
reaction also needs to be carefully controlled. Generally speaking, the reaction rate is slow at low temperatures, and high temperatures may cause side reactions. Therefore, the temperature is usually controlled between 0 ° C and room temperature, and the specific temperature varies according to the reaction process and the purity requirements of the product.
After the reaction is completed, the product needs to be separated and purified. By column chromatography, a suitable adsorbent and eluent can be selected to separate 5-chloro-2-iodophenol from the reaction mixture, and then a pure product can be obtained.
Or starting from 2-chlorophenol and reacting with an iodizing reagent, similarly, 5-chloro-2-iodophenol can be obtained by selecting an appropriate iodizing agent, solvent, and controlling the reaction temperature. However, no matter what method, the reaction conditions need to be carefully considered to obtain the expected product.
What are the precautions in storage and transportation of 5-chloro-2-iodophenol?
5-Chloro-2-iodophenol is an organic compound. When storing and transporting, pay attention to the following things:
First, the storage place must be dry and cool. This substance is afraid of moisture and moisture, and moisture is easy to deteriorate; if the temperature is too high, it may also cause chemical reactions. Therefore, it is advisable to choose a well-ventilated and low-temperature storage, so as to ensure the stability of its chemical properties.
Second, it must be kept away from fire and heat sources. 5-chloro-2-iodophenol is flammable. In case of open fire or hot topic, there is a risk of fire and explosion. Fireworks are strictly prohibited in the storage place, and electrical equipment should also meet the requirements of fire and explosion prevention.
Third, it should be stored separately from oxidants and acids. 5-chloro-2-iodophenol is chemically active, and contact with oxidants and acids may cause violent reactions, resulting in danger. When storing, it must be divided and classified, and cannot be mixed.
Fourth, when transporting, the packaging must be stable. Use suitable packaging materials to ensure that the substance does not leak during transportation. The packaging should be collision-resistant, vibration-resistant, and have clear warning signs.
Fifth, the transportation vehicle should be equipped with corresponding safety equipment. Such as fire extinguishers, leakage emergency treatment tools, etc. In the event of an accident, it can be responded to in time to reduce hazards.
Sixth, the operator must undergo professional training. Familiar with the characteristics and safe operation specifications of 5-chloro-2-iodophenol, strictly follow the rules during transportation and storage, and prevent accidents caused by improper operation.
5-chloro-2-iodophenol impact on the environment and people
5-Chloro-2-iodophenol, this is an organic compound. Looking at its impact on the environment and the human body, its characteristics need to be investigated in detail.
In terms of the environment, if such organic compounds are released into nature, their fate is quite complicated. Its chemical structure gives a certain stability, so it is difficult to degrade in the environment. Or it remains in the soil, causing soil quality deterioration and affecting vegetation growth. Because soil microorganisms have limited ability to decompose it, long-term accumulation, or change the physical and chemical properties of the soil, breaking the ecological balance of the soil. Inflow into water bodies also harms aquatic organisms. Because it has certain toxicity, or interferes with the normal physiological functions of aquatic organisms, such as affecting fish respiration and reproduction, causing population loss. And it is transmitted and enriched through the food chain, and it also poses a threat to higher organisms.
As for the human body, the risk of exposure to this compound is very high. After skin contact, it can penetrate the skin barrier, enter the blood circulation, and damage the organs in the body. Inhalation of its volatile gaseous substances can harm the respiratory system, causing respiratory inflammation and allergic reactions. Accidental ingestion, or damage the digestive system, causing vomiting, diarrhea and other diseases. Long-term exposure, or carcinogenic risk. Because of certain groups in its chemical structure, or interaction with human cell DNA, it can cause genetic mutations, which in turn can induce cancer. And it may interfere with the human endocrine system, affect hormone balance, and have adverse effects on human growth, development, reproduction and other physiological processes.
In summary, 5-chloro-2-iodophenol is potentially harmful to both the environment and the human body. When producing and using this compound, proper protection and handling measures should be taken with caution to reduce its adverse effects on the environment and the human body.