5 Hydroxyacetyl Amino N N Bis 2 3 Dihydroxypropyl 2 4 6 Triiodo 1 3 Benzenedicarboxamide

This is "5- [ (hydroxyacetyl) amino] -N, N '-bis (2,3-dihydroxypropyl) -2,4,6-triiodo-1,3-benzenedicarboxamide", and its chemical structure is analyzed as follows:
Looking at its name, this compound contains many structural fragments. Starting from the benzene ring, this is the core structure. The 1,3 positions of the benzene ring are connected to the dicarboxylamide group, that is, the -CONH-group, in which the nitrogen atom of the two amide groups is respectively connected to a specific substituent. One is N, N' -bis (2,3-dihydroxypropyl), which means that two 2,3-dihydroxypropyl groups are connected to the nitrogen atom. The structure of 2,3-dihydroxypropyl is -CH ² CH (OH) CH 2O OH, which endows the compound with a certain hydrophilicity.
Furthermore, the 2,4,6 positions of the benzene ring are replaced by iodine atoms, and the introduction of iodine atoms makes the compound have unique physical and chemical properties. The iodine atom has a large relative atomic weight, or affects the density and solubility of the compound.
5-position contact [ (hydroxyacetyl) amino] fragment, which is composed of hydroxyacetyl groups connected to amino groups. The hydroxyacetyl group structure is -CH -2 OHCO -, which is connected to the benzene ring through amino groups.
Overall, the structure of this compound is complex, and the interaction of each structural fragment affects its physical, chemical and biological activities. Different substituents endow them with various properties such as hydrophilicity and specific reactivity, or have specific uses in the fields of medicine and chemical industry.

5 - [ (hydroxyacetyl) amino] - N, N '- bis (2,3 - dihydroxypropyl) - 2,4,6 - triiodo - 1,3 - benzenedicarboxamide, the Chinese name is often iodoxanol, this drug is mainly used in the following medical procedures:
iodoxanol is a non-ionic, dibody, hexaiodine, water-soluble contrast agent. In modern medical institutions, it is often used for X-ray angiography and CT enhanced examination. In the field of angiography, such as coronary angiography, coronary arteries can be clearly developed, which can help physicians understand whether blood vessels are narrowed or blocked, and provide a key basis for the diagnosis and treatment planning of coronary heart disease. For cerebral angiography, it can help physicians clarify the shape, course, and abnormalities and lesions of cerebral blood vessels, which is of great significance for the diagnosis and treatment of cerebral vascular diseases.
In terms of CT enhancement, whether it is abdominal CT enhancement to distinguish the nature of lesions in organs such as the liver and pancreas, and to distinguish between benign and malignant tumors; or chest CT enhancement to observe lung nodules, mediastinal lesions, etc., iodoxanol can enhance the contrast between tissues, allowing the lesion site to be more clearly presented, greatly improving the accuracy of disease diagnosis. With its relatively low osmotic pressure and other characteristics, it not only guarantees the effect of imaging, but also reduces the probability of adverse reactions to a certain extent, providing strong support for physicians to accurately diagnose diseases and rationally apply medicine to treat diseases. It plays an important role in current medical diagnosis.

5 - [ (hydroxyacetyl) amino] - N, N '- bis (2,3 - dihydroxypropyl) - 2,4,6 - triiodo - 1,3 - benzenedicarboxamide is a specific chemical substance. Its safety is related to many aspects and needs to be investigated in detail.
The safety of this substance lies first in its chemical properties. Its structure contains iodine atoms. Although iodine is an element needed by the human body, excessive intake or adverse reactions may occur. There are many complex functional groups, or chemical reactions with substances in the body, which affect physiological functions.
Furthermore, toxicity studies are indispensable. If animal experiments are carried out, its effects on different organs can be observed. If ingested for a long time, it may increase the burden on the liver and kidneys, and its metabolism may require passing through these two organs. If the dose is too high, it may cause serious consequences such as cell damage and gene mutation.
From an environmental perspective, its safety cannot be ignored. If it flows into the natural environment, it may affect aquatic organisms, soil microorganisms, etc. Because of its complex structure, or it is difficult to be naturally degraded, and then accumulate in the environment.
In terms of human application, if it is used for medicinal purposes, it must undergo strict clinical trials. To consider its efficacy, we should also pay attention to adverse reactions. Such as allergic reactions, or due to individual differences, some people will experience rashes, itching, and even breathing difficulties after exposure to this substance.
To fully understand the safety of 5 - [ (hydroxyacetyl) amino] - N, N '- bis (2,3 - dihydroxypropyl) - 2,4,6 - triiodo - 1,3 - benzenedicarboxamide, in-depth research in multiple fields is required, and accurate judgments can be made by synthesizing chemical, toxicological, environmental and human application results.

To make 5-%5B%28hydroxyacetyl%29amino%5D-N%2CN%27-bis%282%2C3-dihydroxypropyl%29-2%2C4%2C6-triiodo-1%2C3-benzenedicarboxamide, the method is as follows:
First, all kinds of raw materials need to be prepared, such as compounds containing iodine, organic matter with specific hydroxyl groups, etc., all of which need to be selected to ensure purity and no impurities.
Then in a clean reactor, according to the exact ratio, the raw materials are placed in sequence. Temperature control is extremely critical, and it is necessary to slowly raise or lower the temperature according to the process of the reaction, so as to maintain it in a suitable range, so as to promote the smooth reaction. Or use a specific catalyst to increase the rate of reaction, but the amount of catalyst also needs to be precisely controlled, and most of them may cause side reactions to occur, and at least the catalytic work is not obvious.
When the reaction is under close observation, observe the change of its color and state to stop the progress of the reaction. After the reaction is completed, the technique of separation and purification is applied. Filtration can be used first to remove solid impurities; then distillation, extraction and other methods can be used to separate the product from the reaction mixture to obtain a pure product.
The whole process requires craftsmen to uphold a rigorous heart and not be sloppy in order to obtain high-quality 5-%5B%28hydroxyacetyl%29amino%5D-N%2CN%27-bis%282%2C3-dihydroxypropyl%29-2%2C4%2C6-triiodo-1%2C3-benzenedicarboxamide.

5 - [ (hydroxyacetyl) amino] - N, N '- bis (2,3 - dihydroxypropyl) - 2,4,6 - triiodo - 1,3 - benzenedicarboxamide is an organic compound. Generally speaking, this substance is measured by the following Quality Standards:
1. ** Chemical Purity **: This is a key indicator, which is related to the purity of the compound. Measured by high-performance liquid chromatography (HPLC), the purity of high-purity products often needs to reach more than 98%, or even 99% or even higher. Insufficient purity, or impurities affect its performance and application effect.
2. ** Appearance properties **: Generally, it is white to off-white crystalline powder with uniform color and no foreign matter. If the appearance color is abnormal or there are visible impurities, or it indicates that the product quality is poor.
3. ** Melting point **: The compound has a specific melting point range. Accurately measured by a melting point meter, the melting point data can assist in judging its purity and crystal form. If the measured melting point deviates too much from the theoretical value, or indicates that there is a quality problem with the product.
4. ** Moisture content **: It is commonly determined by the Carl Fischer method. Excessive moisture may affect the stability and chemical reaction activity of the compound. Usually, the moisture content should be strictly controlled at a low level, such as less than 0.5%.
5. ** Related substances **: Detect relevant impurities with the help of HPLC and other analytical methods. Impurities or residual reactants, intermediates and by-products originating from the synthesis process need to be limited in their type and content to ensure product quality and safety.
6. ** Heavy metal content **: Determination of heavy metals such as lead, mercury and cadmium by atomic absorption spectrometry. Heavy metals are extremely harmful, so their content should meet strict standards to ensure that products are safe when used in medicine, biology and other fields.