What is the chemical structure of 5-iodo-1-pentofuranosylpyrimidine-2, 4 (1h, 3h) -dione?
5-Iodo-1-pentofuranosylpyrimidine-2,4 (1H, 3H) -dione, its chemical properties are worth exploring. This compound is named after the chemical. "5-iodo" indicates that there is an iodine atomic phase at a specific position, that is, the fifth position. Iodine, a group element, is a sexual activity. In this compound, its properties must be affected.
"1-pentofuranosyl" part shows that there is a furanosyl group composed of five carbons, which is the first. The presence of a furanosyl group gives the properties of sugar derivatives of this compound, and its immediate and empty image, or the activity and reaction of the compound have a qualitative effect.
"pyrimidine-2,4 (1H, 3H) -dione", which reveals that its core pyrimidine is low, and at the 2nd and 4th positions, it has a carbonyl group. For pyrimidine, in the biological and chemical fields, it often contains important active groups, such as polynucleic acid groups. This carbonyl group does not affect the properties of molecules, and it is also the reaction of multiplication, such as nuclear addition.
The combination of 5-iodo-1-pentofuranosylpyrimidine-2,4 (1H, 3H) -dione is composed of iodine atom, furanosyl group and pyrimidine containing carbonyl group. The interaction of each part gives the compound its unique chemical and biological properties, and is in the field of chemical synthesis, chemical research, etc., or multi-force storage.
What are the main uses of 5-iodo-1-pentofuranosylpyrimidine-2, 4 (1h, 3h) -dione?
5-iodo-1-pentofuranosylpyrimidine-2, 4 (1H, 3H) -dione, this is a chemical substance, its common nickname may be iodine glycoside. This substance has important uses in the field of medicine.
In the way of antiviral, iodine glycoside can be used as an antiviral drug. In the past, its eye drops were often used to deal with eye infections caused by herpes simplex virus, such as herpetic keratitis. The reason for its action is that it is similar in structure to thymine nucleoside and can be mixed with the DNA of the virus, which then interferes with the nucleic acid synthesis of the virus and inhibits the proliferation of the virus.
However, this drug also has limitations. When used locally, it is easy to cause eye pain, itching, redness and swelling and other irritating symptoms. Long-term use may also cause small spots or cloudy corneal staining, allergic reactions, etc. And due to the emergence of drug resistance and new antiviral drugs, clinical application has become less and less.
In addition to the field of medicine, 5-iodo-1-pentofuranosylpyrimidine-2, 4 (1H, 3H) -dione may also be used in biochemistry and molecular biology research. It may be used as a tool to explore topics such as nucleic acid synthesis and viral replication mechanisms, helping researchers understand the mysteries of life processes. Although the current application is not as extensive as in the past, its historical significance in antiviral research is profound, and it also paves the way for the development of subsequent antiviral drugs.
What are the physical properties of 5-iodo-1-pentofuranosylpyrimidine-2, 4 (1h, 3h) -dione?
5-iodo-1-pentofuranosylpyrimidine-2, 4 (1H, 3H) -dione is an organic compound. The physical properties of this compound are as follows:
In terms of appearance, it is often white to off-white crystalline powder, which makes it easy to identify in the solid state. The fineness of the powder may vary slightly due to the preparation process.
Melting point is an important indicator to measure the physical properties of the compound. Its melting point is roughly within a specific range. Due to different precise measurement conditions or slight fluctuations, it is generally near a specific temperature. The temperature is the critical temperature for its transformation from solid to liquid, which is of great significance for its identification and purity judgment.
Solubility is also a key property. The solubility of this compound varies in common organic solvents. In polar organic solvents, such as methanol and ethanol, or with a certain solubility, a homogeneous and dispersed solution can be formed; in non-polar organic solvents, such as n-hexane and toluene, the solubility is relatively low, or only slightly soluble or even insoluble. This difference in solubility is closely related to the existence and distribution of polar groups in its molecular structure, which is helpful for the selection of suitable solvents in the separation, purification and preparation process.
In addition, the density of the compound is also one of its physical properties. Although the specific value varies according to the accurate measurement method and conditions, it has a relatively stable density range under the established standard conditions. This density characteristic is of important value in the material balance and process design of the compound.
Its stability is relatively good at room temperature and pressure, but when exposed to high temperature, strong light or specific chemical environment, or chemical changes occur, the stability will be affected, which will affect its physical properties. These many physical properties are interrelated and jointly determine the behavior and application of 5-iodo-1-pentofuranosylpyrimidine-2, 4 (1H, 3H) -dione in different scenarios.
What are the synthesis methods of 5-iodo-1-pentofuranosylpyrimidine-2, 4 (1h, 3h) -dione?
5-Iodine-1-pentanofuranosylpyrimidine-2,4 (1H, 3H) -dione, this is an organic compound, and its synthesis method is very important. In the past, the synthesis of this compound often followed a specific organic reaction path.
Initial steps, or suitable starting materials need to be selected. For example, starting with compounds containing pentanofuranosyl groups and raw materials containing pyrimidinedione structures. The pentanofuranosyl group can be linked to pyrimidinedione by glycosylation. In this reaction, the catalyst and reaction conditions need to be carefully selected. Commonly used catalysts, or acid or base catalysts, but the amount and type need to be precisely regulated to avoid side reactions.
When glycosylation reactions, temperature and reaction time are also critical. If the temperature is too high, it may cause the product to decompose or produce too many by-products; if the temperature is too low, the reaction rate will be slow and time-consuming. Therefore, it is often necessary to react in a specific temperature range, such as by moderate heating or cooling to maintain a stable temperature.
When the sugar groups are successfully connected, iodine atoms may need to be introduced. The method of introducing iodine atoms can be achieved by halogenation reaction. In this process, it is important to choose a suitable halogenation reagent. Common iodine substitutes can replace hydrogen atoms at specific positions with iodine atoms. This halogenation reaction also needs to pay attention to the reaction conditions, such as the choice of solvent, suitable solvent can promote the reaction and help the product separation.
Throughout the synthesis process, after each step of the reaction, it is necessary to use analytical methods such as chromatography and spectroscopy to identify the purity and structure of the product. Make sure that the product in each step is correct before entering the next step of the reaction, so that the target product 5-iodine-1-pentafuranosylpyrimidine-2,4 (1H, 3H) -dione can be obtained. The details of each step of the reaction need to be carefully controlled to improve the success rate of synthesis and the quality of the product.
What are the potential side effects of 5-iodo-1-pentofuranosylpyrimidine-2, 4 (1h, 3h) -dione?
5-iodo-1-pentofuranosylpyrimidine-2, 4 (1H, 3H) -dione, that is, 5-iodine-1-pentanofuranosylpyrimidine-2,4 (1H, 3H) -dione, this substance has many potential side effects, which cannot be ignored.
In terms of human physiology, it may affect the digestive system. After taking it, some people may experience nausea and vomiting, because after the substance enters the body, it stimulates the gastrointestinal mucosa and disrupts the normal digestive order. And intestinal peristalsis may also be disturbed by it, causing diarrhea or constipation, and the balance of intestinal flora may be broken, which in turn affects the overall digestive function.
It also has potential threats to the nervous system. Or cause dizziness and headache, this is because the substance affects the transmission of neurotransmitters and interferes with the normal signal transduction of the nervous system. Long-term or large-scale exposure is more likely to cause memory loss, inattention, and adverse effects on the cognitive function of the nervous system, affecting daily work and life.
Furthermore, it also affects the immune system. Or inhibit the activity of immune cells and reduce the body's immunity. As a result, the body's ability to resist external germs is weakened, and it is more susceptible to various diseases. The frequency of colds, infections and inflammation may increase, which brings many hidden dangers to health.
In short, 5-iodo-1-pentofuranosylpyrimidine-2, 4 (1H, 3H) -dione has many potential side effects in the human body. When using it, be careful, pay close attention to the body's reaction, and seek medical diagnosis in time if necessary to protect health.