5-Iodo-1H-Imidazole

Fengxi Chemical

Specifications

HS Code	506187
Chemical Formula	C3H3IN2
Molecular Weight	194.0
Appearance	Solid
Color	Typically white to off - white
Odor	May have a faint characteristic odor
Solubility In Water	Low solubility
Solubility In Organic Solvents	Soluble in some organic solvents like ethanol
Melting Point	Around 165 - 168 °C
Boiling Point	Decomposes before boiling
Stability	Stable under normal conditions, but may react with strong oxidizing agents
Purity	Can be available in high purity grades (e.g., 98%+)
Chemical Formula	C3H3IN2
Molecular Weight	194.0
Appearance	Solid
Color	Typically white to off - white
Melting Point	190 - 194 °C
Solubility	Soluble in some organic solvents like DMSO
Purity	Can be found in various purity grades, e.g., 95%+
Stability	Should be stored in a cool, dry place away from light
Cas Number	23906 - 68 - 1
Synthesis Method	Can be synthesized through reactions involving imidazole and iodine - containing reagents

As an accredited 5-Iodo-1H-Imidazole factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage

Packing	5 - iodo - 1H - imidazole packaged in 100 - gram vials for chemical use.
Storage	5 - iodo - 1H - imidazole should be stored in a cool, dry place away from heat sources and direct sunlight. Keep it in a tightly sealed container to prevent moisture absorption and potential reaction with air components. Store it separately from incompatible substances, such as strong oxidizers or bases, to avoid chemical reactions that could compromise its integrity.
Shipping	5 - iodo - 1H - imidazole is shipped in well - sealed, corrosion - resistant containers. Shipment follows strict chemical transport regulations, ensuring proper handling to prevent spills and maintain the integrity of the chemical during transit.

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General Information

Historical Development

5-Iodine-1H-imidazole is a special substance of chemistry. Its origin can be traced back to the past. At the beginning, many scholars delved into chemical substances and explored the unknown. At that time, their properties and production methods were all ignorant.
After the years passed, various sages made unremitting efforts. In the laboratory, after countless attempts, they analyzed its ingredients and explored its reactions. Or change the conditions, or change the reagents, and finally get the method of preparation. The method is gradually refined, and the yield also rises.
The use of this compound has not yet been apparent. However, scholars continue to study its properties in detail, and then found that it is promising in fields such as medicine and materials. With the advance of science and technology, its research has deepened, and the future path will be broader, which will add to the rise of chemistry and expand infinite possibilities.

Product Overview

5-Iodine-1H-imidazole is an important chemical compound in chemical research. Its appearance or specific form has unique properties. This compound plays a key role in many chemical processes, or can participate in specific reaction paths, through which various chemical transformations can be achieved. The uniqueness of its structure endows it with special chemical activity and reaction tendency.
During experimental investigation, the preparation process must be carefully controlled. Many factors such as reaction temperature and reactant ratio have a significant impact on the purity and yield of the product. And in the field of organic synthesis, or as a key intermediate, it helps to synthesize more complex compounds with special functions. In the vast world of chemical research, the research and application prospects of 5-iodine-1H-imidazole are broad, and we need to explore it in depth to understand its more mysteries and potential.

Physical & Chemical Properties

5 - Iodo - 1H - Imidazole is also a chemical substance. Its physical appearance is often solid, color or white or nearly white, crystalline shape, with a certain degree of melting, and can be used. Its solubility is soluble in some soluble substances, but the solubility of water needs to be explored.
As far as chemical properties are concerned, it has a special chemical activity because it contains iodine atoms and imidazole atoms. Iodine atoms can be polysubstituted and reversed, and imidazole atoms can also exhibit chemical properties, and can be reactive to acid substances. And because of its special properties, it can be used in the field of chemical synthesis, or it can be used for important synthesis, and it is useful for the development of chemical research and related research.

Technical Specifications & Labeling

Today there is 5 - Iodo - 1H - Imidazole, which is the key to the study of process specifications and identification (product parameters). Looking at its process specifications, it is necessary to clarify the method of synthesis, the geometry of the materials used, and the steps, all of which must be detailed. Synthetic materials must be well selected, accurately proportioned, and operated in sequence to obtain high-quality products.
As for the identification (product parameters), its characteristics, purity, impurity content, etc., all need to be clearly marked. Characters should be observed for their color, state, and taste; purity is related to quality and must be determined by accurate methods; impurity content cannot be ignored, and must be strictly controlled within the allowable value. In this way, detailed study of process specifications and identification (product parameters), to obtain 5 - Iodo - 1H - Imidazole quality products to meet the needs of all parties.

Preparation Method

5 - Iodo - 1H - Imidazole is an important chemical, and its preparation method is related to many factors.
The raw materials are selected, and imidazole and iodine sources are commonly used. Iodine sources such as potassium iodide and iodine elements can be used as the basis for introducing iodine atoms. Potassium iodide has a wide range of sources and is affordable, and iodine elements have high activity, each with its own strengths.
Preparation process, imidazole and iodine are reacted with appropriate solvents and catalysts. Common solvents such as dichloromethane, ethanol, etc., can provide a good environment for the reaction. The catalyst can be selected with copper salt or palladium salt to accelerate the reaction process.
In the reaction step, first dissolve imidazole in solvent, add a catalyst, and slowly add an iodine source. Control the reaction temperature and time, and react at about 50-80 ° C for 2-4 hours, stirring continuously. When the reaction is completed, cool, filter, and collect the filtrate.
Purification mechanism, column chromatography or recrystallization can be used. Column chromatography can effectively separate impurities, and recrystallization can improve the purity of the product. After these steps, a relatively pure 5-Iodo-1H-Imidazole can be obtained.

Chemical Reactions & Modifications

5 - Iodo - 1H - Imidazole is an important chemical substance, and its chemical reaction and modification are extremely critical. In various experiments in the past, under specific reaction conditions, its encounter with a certain reagent can trigger a unique chemical reaction.
Initially, the reaction is mild, but it changes with fine-tuning conditions, such as temperature rise and fall, catalyst increase or decrease, reaction rate and product quality and quantity. In this case, the modification is aimed at optimizing its performance. Or introduce specific functional groups to enhance the chemical activity of 5 - Iodo - 1H - Imidazole, showing better characteristics in some application scenarios. Or change the spatial configuration of its molecular structure to improve its physical properties, such as solubility and stability. After repeated exploration and adjustment, the law of its chemical reaction and the method of modification are gradually clarified, which lays a solid foundation for the in-depth application and research of this substance in the future.

Synonyms & Product Names

5-Iodine-1H-imidazole, the nickname and trade name of this product are quite important. Its nickname may vary depending on its properties and preparation methods. Such as its iodine-containing sign, or those called iodine-imidazole. Trade names vary depending on the business.
Businesspeople put profit first, and if they want to make this product widely known, they must choose a trade name that is easy to remember and shows their superiority. However, whether it is a nickname or a trade name, it must be clear that it is 5-iodine-1H-imidazole. Chemical substances, although the name is correct, although the nickname and trade name are complex, they are all specific substances. Researchers should investigate them carefully to avoid confusion and errors in scientific research.

Safety & Operational Standards

5-Iodine-1H-imidazole is also a chemical substance. Its safe production and operation practices should be used with caution.
Preparation of this product, all raw materials and reagents must be pure and good, and storage must also be appropriate. Avoid hot topics and open flames, and store them according to categories to prevent their deterioration and reaction.
When operating, the operator should be in front of appropriate protective equipment, such as protective clothing, gloves and goggles, to prevent skin, eyes and toxins from coming into contact. And in a well-ventilated place, set up a waste gas treatment device to prevent harmful gases from overflowing in the room.
The reaction process, temperature, pressure, time and other factors must strictly follow the set parameters. Add reagents slowly to stabilize the reaction rate and avoid its excesses. If there is any abnormality, stop the operation quickly and check the cause to ensure safety.
When the product is separated and purified, choose appropriate methods, such as crystallization, distillation, extraction, etc. During operation, pay attention to the volatilization and recovery of solvents to reduce their loss and pollution.
Store the finished product, use a sealed device, and mark the product name, specification, date, etc. Store in a cool, dry and ventilated place to isolate fire sources and oxidants.
When handling, handle it with care to prevent the container from being damaged and leaking. In case of leakage, immediately open an emergency case, surround and control the scene, and evacuate unrelated people. Small leaks should be collected by adsorption of sand, vermiculite and other substances; large leaks should be dammed and contained, and then properly disposed of.
All production and operation of 5-iodine-1H-imidazole must follow this safety and operation specification to ensure personnel safety, good environment, and smooth production.

Application Area

5 - Iodo - 1H - Imidazole is also a chemical substance. It can be used as a raw material for the synthesis of multi-effect materials in the field of production. With its special properties, it can generate a variety of reactions and help form molecules with effects.
In the field of materials, it is also useful. It can improve the properties of materials and increase their qualitative and low-quality properties. In the process of chemical research, it is often used as a catalyst, which can promote the reaction rate, speed up the reaction rate, and make it more efficient.
And because of its characteristics of reaction activity, it can be used as a part of the catalytic reaction, so as to develop its important value in many fields.

Research & Development

5 - Iodo - 1H - Imidazole is an important chemical substance, and its research and development are crucial in our field of chemical research. We have dedicated ourselves to studying this compound to investigate its properties, structure and reaction mechanism in detail. After many experimental investigations, its unique reaction characteristics under specific conditions have been clarified, which may provide an opportunity for the development of new synthetic methods.
Looking at its development prospects, it is expected to emerge in the fields of medicine, materials and other fields. In medicine, it may be used as a key intermediate to help create new drugs; in the field of materials, its unique structure may endow materials with novel properties. We will continue to conduct in-depth research, strive to expand its application scope, promote the further development of this compound, and contribute to the progress of the chemical field.

Toxicity Research

Fu 5 - Iodo - 1H - Imidazole, the study of its toxicity is of the utmost importance. Looking at the experience of all poisons in the past, they are all related to the safety of living beings. Now at 5 - Iodo - 1H - Imidazole, it is time to investigate its entry path, either orally, percutaneously, or breathing.
Observe its impact on the organism, at the cellular level, to see if it damages the structure and function of cells, such as breaking cell membranes and disrupting the operation of cell organs. In animal experiments, the heart, liver, kidney, etc. should not be ignored. Observe the change in behavior, whether there is a sign of sluggishness and listlessness.
Furthermore, explore the mechanism of its toxicity, whether it interferes with biochemical reactions or affects gene expression. Only by studying this in detail can we know the true meaning of the toxicity of 5-Iodo-1H-Imidazole, so as to prevent and use it to ensure the well-being of all living beings.

Future Prospects

5-Iodo-1H-Imidazole is unique and has extraordinary potential. The future development has vast prospects. Or it can be used in various ways of medicine to cure all kinds of diseases and save the sick. Or in the field of materials, it has emerged and contributed to the rise of new materials. Its structure is exquisite and contains endless possibilities, waiting for our scientific researchers to explore it carefully. With time, it will surely shine, benefit the world, and benefit everyone. This is our eagerness for its future development.

Historical Development

5-Iodine-1H-imidazole is also a chemical product. At the beginning, no one knew this thing. Later, through the study of various sages, it gradually became clear about its nature. In the past, the public explored in subtle places and tried it repeatedly to investigate the mystery of this substance. At the beginning, progress was slow, but the ambition of the sages remained unchanged, and they worked tirelessly.
Years have passed, technology has advanced, and the understanding of 5-iodine-1H-imidazole has also increased. It can be used for medical research and development, or to help create materials, and its use is gradually expanding. From its initial appearance to today's achievements, it all depends on the diligence of researchers of all dynasties, and on the path of chemistry, step by step, in order to have the development of this substance today.

Product Overview

5-Iodine-1H-imidazole is also an organic compound. Its shape is either crystalline, and its color is white. This compound is widely used in the field of organic synthesis.
In many reactions, 5-iodine-1H-imidazole is often the key raw material. Its iodine atom has active chemical properties and can react with a variety of reagents to form rich and diverse organic molecular structures.
Preparation of this compound follows a specific chemical path. Or it is carefully prepared by imidazole as the starting material and through a series of steps such as halogenation. Its purity and quality are related to the effectiveness of subsequent application.
In the field of medicinal chemistry, it may participate in the creation of new drug molecules; in the field of materials science, it may also be an important component in the construction of special performance materials. All these show the important position of 5-iodine-1H-imidazole in chemical research and application.

Physical & Chemical Properties

5-Iodine-1H-imidazole is also a chemical substance. Its physical and chemical properties are particularly important. Looking at its shape, under normal conditions, or in the shape of a powder, the color is white and the quality is uniform. Its melting point, after precise measurement, is about a certain value. This value is a key indicator when identifying and purifying.
When it comes to solubility, it varies among various solvents. In polar solvents, such as alcohols, the degree of solubility varies, or it is partially soluble, or it can be well blended, depending on the intermolecular forces. Its chemical properties are active, and it can be used as an important raw material or intermediate in many chemical reactions. Due to its iodine-containing atom and imidazole ring, it is endowed with unique reactivity and can participate in various reactions such as nucleophilic substitution and cyclization. It is widely used in the field of organic synthesis and is of great importance to chemical researchers. Exploring its properties can lay a solid foundation for the creation of new substances and the development of new reaction paths.

Technical Specifications & Labeling

Today there is 5 - Iodo - 1H - Imidazole, which is unique among chemical substances. Its technical specifications and identification (commodity parameters) are related to the preparation and quality.
The method of preparation depends on precise steps, the distribution of materials, and the control of heat conditions. The materials used must be selected well, and the weighing must be accurate to obtain good quality.
The quality label is based on purity, and the content of impurities should be controlled in trace amounts. There are also standards for appearance and color, and it should be in a certain state. Its physical parameters, such as melting and boiling point, are all evidence for judgment. Only by following this technical specification and marking can we produce high-quality products that can play their role in chemical applications and lay the foundation for various applications.

Preparation Method

The raw materials of this 5-Iodo-1H-Imidazole are very important to the production process, reaction steps and catalytic mechanism. First, take the appropriate raw materials and mix them in a specific ratio. For example, choose the initial material containing imidazole structure and place it in the same place with the iodine substitution reagent. The reaction steps need to be controlled by temperature and time, and the reaction steps are carried out in a specific reaction vessel in sequence. In the initial stage, adjust the temperature to a certain range, so that the raw materials can initially act, and then gradually adjust the conditions to promote the reaction to produce the target product. The catalytic mechanism
involves adding a specific catalyst to reduce the activation energy of the reaction and increase the reaction rate. When the selected catalyst is highly selective to the reaction, it can efficiently generate 5-Iodo-1H-Imidazole. The production process also needs to be carefully considered. From the pretreatment of raw materials to the purification of the product after the reaction, strict control is required to obtain a high-purity product. In this way, the preparation of this 5-Iodo-1H-Imidazole can be completed.

Chemical Reactions & Modifications

I tried to study chemical things, and I worked hard on this product of 5-Iodo-1H-Imidazole. Its chemical reaction involves many subtleties. At the beginning, according to the usual method, the reaction effect is not as expected, the yield is flat, and impurities are also present.
I think, there are easier conditions for this reaction. Then adjust the temperature, change the solvent, and hope to change. When the temperature rises slightly, the solvent is prone to a certain characteristic, and the reactivity gradually changes. The originally slow reaction gradually becomes more active, the yield also rises, and the impurities gradually decrease.
Looking at this process, the chemical reaction is often not static, and the subtle adjustment may lead to major changes. Each change of conditions, like a chord change tone, different timbre. This example of 5-Iodo-1H-Imidazole demonstrates the wonders of chemical change and improvement. In scientific research, it is necessary to be sensitive to observation and courage to try in order to find the true meaning.

Synonyms & Product Names

5 - Iodo - 1H - Imidazole is also a chemical thing. Its same name is also noted by the industry. The same name of this compound may vary according to its characteristics and properties. The business name is determined, and it is often tested in terms of market conditions and uses.
Those who have been transformed in ancient times, but also have insights into the nature and transformation of things. Today's 5 - Iodo - 1H - Imidazole, in chemical research and development, has its uses. Its similarities help researchers to communicate with each other, and the business name is easy to circulate in the market.
The transformation of this product makes our understanding of this product deeper and deeper. 5 - Iodo - 1H - Imidazole is the same business name, which is a corner of the development of knowledge and development, showing that we are constantly exploring, using the secrets of things to the world.

Safety & Operational Standards

5-Iodine-1H-imidazole safety and operating specifications
Fu 5-iodine-1H-imidazole is also a commonly used product in chemical research. Although its nature is not extreme, it should be carefully followed during the use and operation to ensure safety.
Anyone involved in this thing should be protected first. When handling, it is advisable to wear complete protective clothing, wear anti-corrosion gloves, and wear protective glasses to prevent it from touching the body and entering the eyes, causing damage to the skin and eyes. And in the laboratory, ventilation must be well-equipped to ensure smooth air, so as to prevent the accumulation of volatile gas and damage to people's health.
When storing, choose a cool, dry and well-ventilated place, away from fire and heat sources. Do not mix with oxidants, strong alkalis and other substances to prevent unexpected reactions. The container must be sturdy and airtight, marked with a clear name, which is clear to people at a glance.
When taking it, the action should be slow and careful. Measure with clean utensils, operate with precision, and do not spill. If there is any accidental spill, clean it up immediately. First absorb with inert materials, and then dispose of it properly. Do not leave it on the table or the ground.
In the experimental operation room, strictly abide by the procedures. When heating, control its temperature, step by step, and do not heat up suddenly. During the reaction process, pay close attention to observe its changes. If there is any abnormality, respond quickly.
After completion, clean up the place. All utensils used should be washed and returned in time. Residues should be disposed of in accordance with regulations and should not be disposed of at will to ensure that the environment is clean and not polluted.
In short, the safety and operation of 5-iodine-1H-imidazole should be carried out with caution, and no negligence should be made at all, so that the experiment can be smooth and personnel are safe.

Application Area

5-Iodine-1H-imidazole is an important substance in chemistry. Its application field is quite extensive. In the field of medicine, it can be used as a key intermediate to help create special new drugs to treat various diseases and eliminate diseases for patients. In material research, it also plays an important role, which can improve material properties and make it more suitable for various scenarios. In chemical synthesis, it is a key element of many reactions, helping to generate different compounds and expanding the scope of chemical products. Such as the ancient talents, in different worlds to show their ability, 5 - iodine - 1H - imidazole in various application fields, all play an important role in promoting scientific and technological progress and industry development, just like a beacon, illuminating the road of chemical exploration.

Research & Development

I have been studying chemistry for a long time, called 5-Iodo-1H-Imidazole. This substance has unique properties and has great potential in the field of organic synthesis.
At the beginning, I explored its structure and dissected it in detail to clarify its inner principle. Then, I studied its reaction characteristics, observed its combination with various substances, and recorded the results in detail.
After months of experiments, it gradually became clear that it can quickly combine with a certain type of reagent under specific conditions, and the yield is quite good. This discovery opens up a new way for the synthesis of novel compounds.
Thinking about its application prospects, it may shine brightly in the road of drug development. Therefore, efforts are made to expand, hoping to contribute to the rise of medicine.
So far, the results have begun to appear, but the road ahead is long, and we still need to make unremitting efforts to promote the progress of this material research and development, hoping to make great achievements and add brilliance to the academic community.

Toxicity Research

I am dedicated to the study of poisons, and recently focused on 5 - Iodo - 1H - Imidazole. Detect its properties and explore its toxicology. The color, state and taste of this thing are all carefully investigated. After various experiments, to understand its impact on living beings. Observe its phase and other things, observe its changes. See it in water and liquid, and the reactions are recorded one by one.
After repeated experiments, it is known that 5 - Iodo - 1H - Imidazole has certain toxicity under certain circumstances. It may damage the cells of organisms and disrupt their physiological order. However, in order to fully understand its toxicity, it is still necessary to explore many times, collect extensive data, and study the mechanism of its action in depth, hoping to clarify it in detail, and provide evidence for preventing its harm and using it for its benefit.

Future Prospects

Today, there is a thing called 5-Iodo-1H-Imidazole. In our pursuit of chemistry, its future prospects are really thought-provoking. This thing has unique properties, or in the field of medicine, it brings new opportunities for healing various diseases, can accurately target lesions, and make medicine effective. Or in the field of materials, it has emerged, giving materials novelty, such as enhancing their stability and conductivity.
Our generation should study its theory and its nature with diligence. We hope to use scientific methods to explore its optimal system and expand its application domain. In the future, we may see it shining brightly in the world, for the well-being of everyone, and for the advancement of science and technology. This is the future situation we are looking forward to.

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Frequently Asked Questions

As a leading 5-Iodo-1H-Imidazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What are the chemical properties of 5-iodo-1h-imidazole?

5-Iodo-1H-imidazole is an organic compound. In its molecular structure, the first position of the imidazole ring is a hydrogen atom, and the fifth position is replaced by an iodine atom.
On its chemical properties, first of all, because it contains nitrogen heterocycles, it has certain basicity. The nitrogen atom in the imidazole ring has a lone pair of electrons, can accept protons, and can form salts in an acidic environment. This basic property makes it possible to react with acids to form corresponding salt compounds.
Furthermore, the iodine atom at the fifth position has higher reactivity. Iodine atoms can undergo nucleophilic substitution reactions due to electronegativity and atomic radius. When encountering nucleophilic reagents, iodine atoms are easily replaced, resulting in the derivation of many different compounds. For example, the reaction with reagents containing hydroxyl, amino and other nucleophilic groups can form new carbon-hetero atomic bonds and expand the variety of compounds.
And because it is an aromatic heterocyclic compound, the imidazole ring is aromatic, relatively stable, and is not easy to be oxidized or added. However, under certain conditions, such as strong oxidizing agents or special catalysts, aromatic rings may also react, or other functional groups may be introduced into the ring to enrich its chemical structure and properties.
In addition, 5-iodo-1H-imidazole is widely used in the field of organic synthesis. It can be used as an intermediate to transform into more complex organic molecules through various reactions, and has potential applications in many fields such as medicinal chemistry and materials science.

What are the main uses of 5-iodo-1h-imidazole?

5-Iodo-1H-imidazole, or 5-iodo-1H-imidazole, has a wide range of uses. In the field of medicinal chemistry, it is often the key raw material for the creation of new drugs. The genimidazole ring structure is common in many bioactive molecules. The introduction of 5-iodo-1H-imidazole into iodine atoms can significantly change the physical, chemical and biological properties of compounds, and help to develop antibacterial, antiviral, antitumor and other drugs.
In the field of materials science, it also has outstanding performance. It can be used as an intermediate in organic synthesis to prepare functional materials with special properties, such as optoelectronic materials. Due to its structural properties, it may endow materials with unique optical and electrical properties, making it popular in the fields of organic Light Emitting Diodes (OLEDs) and solar cells.
Furthermore, in the field of organic synthetic chemistry, 5-iodine-1H-imidazole is an important building block for the construction of complex organic molecules. The existence of iodine atoms allows it to participate in a variety of chemical reactions, such as coupling reactions, so that it can efficiently form carbon-carbon and carbon-heteroatom bonds, expand the structural diversity of organic molecules, and provide a powerful means for the synthesis of various fine chemicals and natural products.

What are the synthesis methods of 5-iodo-1h-imidazole?

5-Iodine-1H-imidazole is an important organic compound. Its synthesis methods are diverse and have their own advantages. The details are as follows:
1. ** Using imidazole as the starting material **:
- ** Halogenation reaction **: This is a commonly used method. Dissolve imidazole in suitable solvents, such as dichloromethane, chloroform, etc., and slowly add iodine-containing reagents, such as N-iodosuccinimide (NIS), iodine elemental substance (I ²) and oxidizing agent mixture (such as hydrogen peroxide, perchloric acid, etc.). Taking N-iodosuccinimide as an example, the nitrogen-iodine bond of N-iodosuccinimide is broken during the reaction, and the iodine positive ion attacks the imidazole ring to form 5-iodine-1H-imidazole. This reaction condition is mild and the yield is quite high.
- ** Metal-catalyzed halogenation **: Imidazole can also be halogenated with an iodine source in the presence of a metal catalyst. Commonly used catalysts include copper salts (such as cuprous iodide CuI), palladium salts (such as palladium acetate Pd (OAc) -2), etc. Taking cuprous iodide as an example, in the reaction, cuprous iodide first forms a complex with ligands (such as o-phenanthroline), which enhances the activation ability of the iodine source, and then prompts the selective introduction of iodine atoms into the fifth position of the imidazole ring. Such methods require harsh reaction conditions and require an oxygen-free and anhydrous environment, but can effectively improve the reaction selectivity.
2. ** Construction of an imidazole ring **:
- ** Using 1,2-dicarbonyl compounds, formamide and iodine sources as raw materials **: 1,2-dicarbonyl compounds (such as glyoxal, butanedione, etc.) and formamide under the action of acidic catalysts (such as p-toluenesulfonic acid), first condensate to form an imidazole ring precursor, and then add an iodine source (such as iodine elemental substance, potassium iodide, etc.). In the presence of an oxidizing agent (such as ammonium cerium nitrate CAN), cyclization and iodization are carried out simultaneously to directly generate 5-iodine-1H-imidazole. This route step is streamlined and the raw materials are easy to purchase. However, the reaction conditions need to be
- ** Using nitrile compounds and iodoacetamide as raw materials **: Under the action of strong bases (such as sodium hydride NaH), nitrile compounds and iodoacetamide first undergo nucleophilic addition reaction to generate nitrogenous carbon negative ion intermediates. This intermediate is then cyclized within the molecule to construct an imidazole ring, and iodine atoms are introduced to generate the target product. This method is suitable for the synthesis of 5-iodine-1H-imidazole with a specific structure. The reaction conditions are relatively harsh and the purity of the reactants is very high.

What is the price of 5-iodo-1h-imidazole in the market?

When I look at the world of commerce, the price of goods often varies with changes in time, place, quality and supply and demand. As for the item "5-iodo-1h-imidazole", its market price also follows this law.
At that time, if a new product is first released and there is no competition in the market, its price may be high. The capital for research and development and the novelty of the process all need to be paid for. After a long time, there will be more and more imitators, the process will become more and more mature, and the price may gradually drop.
In terms of location, in a prosperous city, there are many commercial ports, smooth transportation, and convenient logistics, the cost may be slightly lower, and the price may also be cheaper. However, in remote places, transportation is difficult and supplies are inconvenient, so the price will increase.
The quality is different, and the price is also very different. With high purity, few impurities, and strict quality, the price must be higher than usual.
The way of supply and demand is also the reason. If the market is wide and the supply is small, the merchant will raise the price to obtain a big profit; if the supply exceeds the demand, in order to sell the inventory, the price must be reduced to lure.
It is difficult to say the price of "5-iodo-1h-imidazole". For more information, you can consult a chemical material dealer, visit a professional trading platform, or refer to industry reports, so that you can get a near-real price.

What are the storage conditions for 5-iodo-1h-imidazole?

5-Iodo-1H-imidazole is an organic compound, and its storage conditions are crucial, which is related to the stability and quality of this compound. Storage of this substance is the first to dry the environment. Because of its certain hygroscopicity, if the environment is humid, it is easy to cause chemical reactions such as hydrolysis, which will damage its structure and purity. Therefore, when placed in a dry place, such as in a sealed container equipped with a desiccant.
It is secondary to temperature control. It should be stored in a cool place to avoid high temperature. High temperature will greatly increase the activity of molecules, or initiate reactions such as decomposition and polymerization. Usually it is better not to exceed 30 ° C, and it is best to maintain it between 15 ° C and 25 ° C.
Furthermore, it should be protected from light. This substance may be sensitive to light, under light, or cause luminescent chemical reactions, which affect its chemical properties. It should be stored in an opaque container, such as a brown glass bottle, and placed in a dark place.
In addition, the storage place should be away from fire sources, oxidants, etc. Because it is an organic compound, it is flammable and prone to danger in case of fire sources; contact with oxidants, or react violently.
In short, the storage of 5-iodo-1H-imidazole needs to be dry, cool, protected from light, and away from dangerous items, so as to ensure the quality and safety of this substance.