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What is the chemical property of 5-iodo-1h-indole-2,3-dione?
5-Iodo-1H-indole-2,3-dione is also a chemical compound. Its color or light to orange powder is often characterized under normal conditions. In case of open flame, high temperature, flammable, oxidizing, easy to cause strong reaction, so it needs to be carefully stored.
< and solubility, this compound is slightly soluble in water, soluble in many soluble substances, such as dichloromethane, N, N-dimethylformamide, etc. Its molecules contain iodine atoms, carbonyl groups and indole groups, which give it special properties.
In terms of reactivity, carbonyl groups can be nucleoaddition reactive, such as alcohol under acid catalysis, or ester derivatives of the phase. Indole can also perform multiple reactive reactions. For example, under certain conditions, the reactive reaction is substituted on the reactive reaction. Due to the characteristics of the density distribution of the subcloud on the reactive reaction, specific locations are more susceptible to reactive attack. Iodine atoms can also be placed. In the appropriate reactive reaction system, they can be replaced by other functionalities, and many new compounds can be derived. The synthesis of reactive compounds provides the possibility of reproducibility. Therefore, the chemical properties of 5-iodo-1H-indole-2,3-dione are very special, and they are useful in the field of synthesis and phase research.
What are the main uses of 5-iodo-1h-indole-2,3-dione?
5-Iodo-1H-indole-2,3-dione, the Chinese name is often 5-iodine indigo, this is an organic compound that has important uses in many fields.
First, in the field of organic synthesis, it can be a key intermediate. Molecular structures can be expanded or modified by various chemical reactions to prepare other complex organic compounds. For example, by reacting with nucleophiles, different functional groups can be introduced, paving the way for the synthesis of compounds with specific biological activities or physical properties, just like skilled craftsmen use it as a cornerstone to build molecular buildings of different shapes.
Second, in the field of medicinal chemistry, 5-iodine indigo has attracted much attention. Studies have shown that its structure can be modified to endow compounds with specific pharmacological activities. Or it can be used as a potential lead compound, optimized and modified to develop new drugs for the treatment of diseases, just like exploring unknown medical paths and finding a good prescription.
Third, in the field of materials science, due to its unique chemical structure and electronic properties, it may be able to participate in the construction of new functional materials. For example, in organic optoelectronic materials, the optical and electrical properties of materials can be adjusted, which can contribute to the development of new optoelectronic devices, as if adding novel decoration to the hall of materials science.
Fourth, in biochemical research, can serve as a tool molecule. It is used to label biomolecules and explore the biochemical reaction mechanisms and molecular interactions in organisms, just like lighting a light in the microscopic world, helping researchers understand the mysteries of life.
What is the synthesis method of 5-iodo-1h-indole-2,3-dione?
5-Iodo-1H-indole-2,3-dione is 5-iodine-indigo, and its synthesis method is as follows:
Take an appropriate amount of o-nitrotoluene derivative, place it in a clean kettle, and dissolve it with an appropriate organic solvent. Add an appropriate amount of iodine source, such as iodine elemental substance or iodine-containing compound, and add a specific catalyst, such as metal salts or organic bases. Control the temperature within a certain range and stir at a moderate rate to make it fully react. This process needs to be carefully monitored, such as thin-layer chromatography (TLC) and other means to observe the reaction progress. When the reaction reaches the expected level, quench the reaction by appropriate methods.
After that, separate and purify. First, the product is extracted from the reaction system by extraction method and a suitable organic solvent. Then, by column chromatography, the suitable silica gel and eluent are selected, and the purpose of separating impurities and purifying the product is achieved by virtue of their different adsorption and elution abilities for different substances. After drying and other treatments, the pure 5-iodine indigo product is obtained.
There are also those who use anthranilic acid derivatives as starting materials. First, the specific group is modified to introduce iodine atoms. Then, through cyclization reaction, the indole ring structure is constructed, and the oxidation step is followed to form the 2,3-dione structure of 5-iodine indigo. During each step of the reaction, precise temperature control, time control, and proportion of reactants are required, and proper separation and purification are required after each step to ensure the purity and yield of the product.
What is the price range of 5-iodo-1h-indole-2,3-dione in the market?
5-Iodo-1H-indole-2,3-dione, Chinese name or 5-iodinole-2,3-dione. This product is in the market, and its price is uncertain, depending on many reasons.
First, the producers are different, the technology is good or bad, and the materials are fine and coarse, but the price is different. Master craftsman is exquisite, the materials are well selected, the products are pure and beautiful, and the price must be high; small workshop is crude, the materials used are ordinary, and the price is low.
Second, the amount is also related to the price. The purchase volume is huge, and merchants often give it at a favorable price, hoping for long-term friendship and subsequent purchases; if you only ask for a small amount, the price may be expensive.
Third, the supply and demand of the city determines the price. If there are many people in need and few people in supply, the price will rise; if the supply exceeds the demand, the price will drop.
Today in the market, the price per gram may range from tens of gold to hundreds of gold. To get a definite price, you should consult the chemical material supplier, or check it in detail on the e-commerce platform, to know the current price.
What are the relevant safety precautions for 5-iodo-1h-indole-2,3-dione?
5-Iodo-1H-indole-2,3-dione is an organic compound. The relevant safety precautions are as follows:
This substance is potentially toxic and may be harmful to human health if touched or inhaled. During operation, it is necessary to strictly follow protective regulations. Wear protective clothing, such as lab clothes, gloves and goggles, etc., and beware of skin and eye contact. If you accidentally touch it, rinse it with plenty of water immediately and seek medical attention as appropriate.
Because it may be irritating, it is appropriate to operate it in a well-ventilated place, such as in a fume hood, to avoid inhaling its volatiles. If inhaled, it should be moved to a place with fresh air quickly. If the symptoms are not slow, it is also necessary to seek medical attention.
This compound may be flammable. It should be stored in a cool and well-ventilated place away from oxidizing agents to prevent violent reactions.
Furthermore, disposal of waste must also be in compliance. It should not be dumped at will. It should be handed over to a professional treatment agency in accordance with local regulations to ensure that the environment is not polluted. During the operation, the experimental steps and data should be carefully noted in order to detect and deal with accidents. In this way, the operation is safe and the harm is avoided.
