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5-Iodo-2, what is the chemical structure of 3-dihydro-1h-inden-2-amine?
5-Iodo-2,3-dihydro-1H-inden-2-amine is the name of an organic compound. According to its name, its chemical structure can be deduced as follows:
This compound contains the parent nuclear structure of indene (2,3-dihydro-1H-indene). The indene-full structure is formed by fusing a benzene ring with a five-membered ring (cyclopentane). Among them, 1H - indicates that there is a hydrogen atom at the No. 1 carbon site of the five-membered ring.
Looking at its substituent, 5-iodo indicates that there is an iodine atom attached to the 5th carbon position of the inindan parent nucleus; 2-amine indicates that there is an amino group (-NH -2) connected to the 2nd carbon position.
In summary, the chemical structure of 5-iodo-2,3-dihydro-1H-inden-2-amine is the organic compound of the 5th carbon-iodine atom and the 2nd carbon-amino group of the inindan parent nucleus. Its structural characteristics give it unique chemical properties and may have potential uses in organic synthesis and medicinal chemistry.
5-Iodo-2, What are the physical properties of 3-dihydro-1h-inden-2-amine?
5-Iodo-2,3-dihydro-1H-inden-2-amine (5-iodo-2,3-dihydro-1H-indene-2-amine) is an organic compound. It has the following physical properties:
Under normal conditions, it is either a crystalline solid, white as snow or white-like, because of its orderly arrangement of molecules and uniform light reflection, so it presents this color and shape.
Smell it, or a slight special smell, but this smell is not pungent or intolerable, but is due to the combination of specific atoms and groups in the molecular structure, which is transmitted through the air to the olfactory receptors and is perceived.
When it comes to solubility, it has good solubility in organic solvents such as methanol, ethanol, and dichloromethane, just like fish get water. This is because the molecules of these organic solvents and 5-iodine-2,3-dihydro-1H-indene-2-amine molecules can form interactions such as hydrogen bonds and van der Waals forces, so that they can be dispersed. However, in water, its solubility is poor. Due to the large difference between the polarity of water and the polarity of the compound, it is difficult to overcome the intermolecular forces of the compound to dissolve it.
When it comes to the melting point, it has been experimentally determined to be in a certain temperature range, which is determined by the strength of the intermolecular forces. When heated, it is necessary to provide enough energy to break the intermolecular force and turn the solid state into a liquid state. This temperature range is also one of its characteristics.
Its density is relatively higher than that of water, or slightly larger. If it is placed in water, if it is submerged in water, it will sink to the bottom, which is determined by its molecular mass and accumulation method.
The physical properties of 5-iodine-2,3-dihydro-1H-indene-2-amine are of great significance for its applications in chemical synthesis, drug development and other fields. Knowing its solubility can help chemists choose suitable solvents for reaction and separation; knowing the melting point can be used for purity detection and crystallization control.
5-Iodo-2, 3-dihydro-1h-inden-2-amine mainly used in which areas
5-Iodine-2,3-dihydro-1H-indene-2-amine, this is an organic compound. Its application field is quite wide, and it plays a significant role in the field of pharmaceutical research and development. Because of its unique structure or specific biological activity, it can lay the foundation for the creation of new drugs. Or it can be used as a lead compound, carefully modified and optimized by chemists to find drugs with better efficacy and less side effects.
In the field of materials science, it also has its uses. Because of its special chemical structure, it may endow materials with unique electrical and optical properties. For example, in organic optoelectronic materials, it can optimize the characteristics of charge transfer and luminous efficiency of materials, and then be applied to the manufacture of organic Light Emitting Diodes (OLEDs), solar cells and other devices.
In the field of organic synthesis, it often acts as a key intermediate. With its iodine atoms and amino groups, it can construct more complex organic molecular structures through various chemical reactions, providing an effective way for the synthesis of various functional organic compounds, and promoting the development and innovation of organic synthetic chemistry. In short, 5-iodine-2,3-dihydro-1H-indene-2-amine plays an indispensable role in many important fields such as medicine, materials and organic synthesis, and is of great significance to promote the progress of related fields.
What are the synthesis methods of 5-iodo-2, 3-dihydro-1h-inden-2-amine
The synthesis method of 5-iodine-2,3-dihydro-1H-indene-2-amine has been known for a long time. Its method is exquisite, and it is necessary to study various classics in detail to know one or two of them.
One method is also to use 2,3-dihydro-1H-indene-2-amine as the initial material. This material needs to be pure and free of impurities before it can be used as the foundation for subsequent reactions. Take an appropriate amount of this amine first and place it in a clean reaction vessel. This container must be resistant to temperature and pressure to meet the needs of the reaction. Subsequently, introduce a reagent containing iodine. The choice of iodine source is related to success or failure, and it is often appropriate to use iodine elemental substance or iodine compound. Here, the reaction conditions are crucial, and the temperature needs to be precisely controlled, neither too high nor too low. If the temperature is too high, the reaction will be overheated, and it is easy to produce miscellaneous and side products; if the temperature is too low, the reaction will be slow and take a long time. Usually, the temperature is maintained at a specific range, such as under mild heating conditions, about ten degrees Celsius, and it needs to be stirred evenly to allow the reactants to fully contact and promote the reaction. In this way, after a period of reaction, the crude product of the target product can be obtained.
However, this crude product still contains impurities and needs to be further purified. The method of purification can be recrystallization. Choose a suitable solvent, which needs to have good solubility to the product, and when the temperature changes, the solubility varies significantly. The crude product is dissolved in a hot solvent, until it is completely dissolved, and filtered while hot to remove insoluble impurities. Subsequently, the filtrate is slowly cooled, and the product crystallizes and precipitates. After filtration, washing, drying and other steps, pure 5-iodine-2,3-dihydro-1H-indene-2-amine can be obtained.
Another method uses other related compounds as starting materials, and this goal can also be achieved through several steps of reaction. First, a specific aromatic compound is introduced into the structure of the indene ring through specific reactions, such as substitution reactions, addition reactions, etc. In this process, each step of the reaction needs to be carefully operated to control the reaction conditions, such as pH, reaction time, etc. After the indene ring structure is initially formed, the iodine atom is introduced into a specific position through iodine substitution reaction, and finally 5-iodine-2,3-dihydro-1H-indene-2-amine is formed. Each step of the reaction is like a tenon-and-mortise connection, and it cannot be wrong to obtain a pure and high-yield product.
Synthesis methods, although there are different paths, require careful study, insight into the mechanism of the reaction, and control of the details of each link, in order to achieve the synthesis of this compound.
5-Iodo-2, 3-dihydro-1h-inden-2-amine security risk
5-Iodo-2,3-dihydro-1H-inden-2-amine is also an organic compound. In terms of its safety risks, it cannot be ignored. In the structure of this compound, iodine atoms coexist with amine groups, or have certain chemical activity.
The introduction of iodine elements may make the compound participate in chemical reactions under specific conditions. In case of strong oxidants, iodine can present a variety of oxidation states, or lead to oxidation-reduction reactions. This process may release energy, but it may be dangerous if it is in an improper environment, such as a confined space and a large amount.
Furthermore, the amine group is a nucleophilic group and is alkaline. Its alkaline properties may cause the compound to react violently with acids to produce heat and form salts. If the acid is a strong acid, the reaction will be even more severe, or it will cause hazards such as splashing.
Also, many organic compounds are flammable. Although there is no direct information indicating the flammability of this compound, due to its organic properties, it may pose a risk of combustion or even explosion in high temperatures, open flame environments, especially when its vapor is mixed with air to form a flammable mixture.
And organic amine compounds, some of which are biotoxic. The amino structure of 5-iodo-2,3-dihydro-1H-inden-2-amine suggests that it may have adverse effects on organisms, such as contact with the skin, or irritation, allergies; inhalation of its vapor, or damage to the respiratory tract, nervous system, etc.
Therefore, 5-iodo-2,3-dihydro-1H-inden-2-amine has many safety risks. Its preparation, storage, use and other links need to be treated with caution and follow safety procedures to avoid harm.