5-iodo-2-hydroxybenzonitrile

The use of Poria Baizhu Banxia Decoction is widespread. Poria, water infiltration, spleen and heart. Baizhu invigorates the spleen and qi, dryness and dampness, water, sweat and fetus. Banxia can dry and dampness and reduce phlegm, reduce reverse vomiting, eliminate ruffians and disperse knots. The three are combined to play the effects of dryness and dampness to reduce phlegm, strengthen the spleen and stomach.
The main diseases to be used are phlegm drinking. If a person loses the spleen and stomach, the water does not melt, and they gather into phlegm drinking, causing chest and flank to be full, dizziness and heart palpitations and other diseases. Poria Baizhu Banxia Decoction can benefit water infiltration and dampness, reduce phlegm and drink, so that water dampness has a way out, phlegm drinking can
Furthermore, the syndrome of disharmony between the spleen and stomach. Weakness of the spleen and stomach, dereliction of duty in transportation and transformation, easy to cause abdominal distension, loose stools, loss of appetite, etc. Fang Zhongbaizhu strengthens the spleen and nourishes qi to help transportation and transformation, Poria cocos seeps and strengthens the spleen, Banxia and the stomach reduce reverse, co-adjust the spleen, stomach and qi machine, restore the work of spleen and stomach transportation, adjust the spleen and stomach, and get food and drink. The disease of bloating and loose stools can be cured.
It is also used for phlegm-dampness cough. Phlegm-dampness blocks the lungs, the lungs are lost and reduced, and it occurs as a cough, and the amount of expectoration is multi-colored and white. Poria and Baizhu remove dampness to eliminate the source of ph
In addition, for those who are blocked by phlegm and dampness in the genus of vertigo, this soup is also effective. The internal resistance of phlegm and dampness, the clear yang does not rise, and the turbid yin does not fall, causing dizziness in the head. Through the various medicines in the prescription to dry dampness and reduce phlegm, strengthen the spleen and stomach, restore the normal rise of clear yang and decline of turbid yin, and the disease of vertigo can be solved.
In short, Poria Baizhu Banxia Decoction has good effects in many diseases such as phlegm, spleen and stomach disharmony, phlegm-dampness cough, phlegm-dampness vertigo, etc. It is also a good prescription for treating diseases.

There are several ways to prepare 5-fluoroindolacetic acid. One is to start with indoles, introduce fluorine atoms through halogenation, and then perform carboxylation. In this way, appropriate halogenation reagents and reaction conditions need to be selected to make the fluorine atoms precisely connected to the indole position No. 5. When halogenating, or using electrophilic halogenating reagents, it is necessary to pay attention to the regioselectivity to prevent the halogen atoms from misconnecting to other places.
Second, the indole ring can be constructed by ring reaction starting from a benzene ring compound with suitable substituents, and a fluorine group and a carboxyl group can be introduced at the same time. For example, using fluorobenzene derivatives as raw materials, the benzene ring and the nitrogen-containing reagent are closed through multi-step reaction to form an indole structure, and the carboxyl group is cleverly added during the closing process or subsequent reactions. The key to this approach lies in the control of the conditions of the ring-closing reaction and the design of the reaction steps to ensure the formation of the target product.
Furthermore, biosynthesis can also be used. Using specific microorganisms or enzymes, 5-fluoroindole acetic acid can be synthesized by biocatalysis with suitable substrates. The biosynthesis method has the advantages of mild conditions and high selectivity. However, it is necessary to find a biological system that can efficiently catalyze this reaction, and the reaction environment such as temperature, pH value and other factors require strict regulation, so as to achieve the ideal synthesis effect.
In addition, in the chemical synthesis method, the reaction catalyzed by transition metals can also be considered. For example, transition metals such as palladium and copper are used as catalysts to promote the coupling reaction between fluorinated reagents and indole derivatives, and then fluorine atoms are introduced, followed by carboxylation. This rule requires optimizing the type, dosage and ligand of the catalyst to improve the efficiency and selectivity of the reaction. In short, there are various methods for synthesizing 5-fluoroindole acetic acid, each with its advantages and disadvantages, and it is necessary to choose the best one according to the actual needs and conditions.

Alumite, its physical state and quality are unique. Alumite is often in the shape of blocks, granules, or crystals, and its colors vary. The common ones are white, yellow, green and other colors, and the luster is also different. It has the luster of glass or the luster of earth.
In terms of its physical properties, the hardness of alumite is moderate, and it is not the strongest thing. It can be scratched or left marks. Its texture is either dense or slightly loose, but it is brittle to a certain extent. If it is hit with force, it is easy to break and irregular. Its density is slightly heavier than that of ordinary stones, and it can be felt in the hand.
Alumite in water may have a certain solubility. Part of the alumite enters the water, which can give the water a special taste or a weak sour feeling. When it is heated, it also has a unique performance, or melts, or changes color, which varies depending on the type of alumite.
And alumite under light, or has a special optical effect, or refracts a unique light color, or has a certain transparency. Although it is not as clear as jade, it also has its unique charm.
The physical properties of alumite are diverse, which are all the wonders of natural creation. In various uses, it also depends on its unique quality to develop its effectiveness.

When storing and transporting, we should pay careful attention to many matters.
When storing, the first thing to pay attention to is the dryness of the environment. Poria A B is crispy and dry, and if it is in a humid place, it is easy to cause mildew and rot. For example, if it is placed in a damp place, it can be seen that the surface is moldy in a few days, and the color and taste are changed, and its effect is greatly reduced. Therefore, it is advisable to choose a high dry place to avoid the invasion of water vapor.
Next time, it is necessary to prevent pests. Poria A B is rich in nutrients, which is easy to attract insects to covet. It can be stored with prickly ash and asarum. The smell of these two is strong, which can drive away insects and keep the Poria A B crispy intact.
As for transportation, temperature control is crucial. The texture of this crisp is special. If it is overheated, it will melt easily, and if it is too cold, it will cause the texture to deteriorate. In the hot season, transportation should be carried by means of an ice cellar or a cool carriage to prevent it from melting due to heat; when it is cold, it should also be wrapped in felt wool and other materials to prevent it from freezing.
Furthermore, attention should also be paid to vibration. The texture of Poria A and B Crisps may be brittle and soft, and excessive vibration can easily cause breakage. During transportation, it is recommended to keep the loading stable and drive slowly and steadily to avoid bumps and collisions.
The container for transportation should be clean and well sealed. Unclean utensils are easy to stain the Poria cocos A and B crisps; if the seal is not good, it is easy to come into contact with the outside air, causing it to oxidize and deteriorate.
In general, the storage and transportation of Poria cocos A and B crisps ensure that the environment is dry, insect-proof, temperature-controlled, shock-absorbing and the container is suitable, so as to ensure its quality without losing its health-preserving effect.

Poria cocos is a good medicine, which has an important impact on both the environment and human health.
As far as the environment is concerned, Poria cocos grow in the rhizosphere of pine trees, often in deep mountains and old forests in damp places, and their growth depends on a specific ecological environment. The growth process of Poria cocos requires soil porosity, humidity, and air permeability. The existence of its ecological niche is also related to the stability of surrounding biological communities. In mountain forests, Poria cocos and pine roots coexist, participating in the material cycle and energy conversion of forest ecosystems, and playing a silent role in maintaining forest ecological balance.
As for human health, Poria cocos has made great contributions. " The Shennong Materia Medica Canon lists it as the top grade, saying that it "takes it for a long time to calm the soul and nourish the mind, and does not starve and prolong the year". Poria cocos have the effect of promoting water seepage and dampness, which can help the human body expel excess water and dampness. If people's water and dampness stop inside, causing edema, unfavorable urine and other diseases, Poria cocos can make the evil of water and dampness come out of the urine and restore the balance of water metabolism in the human body. And Poria cocos can strengthen the spleen, and the spleen and stomach are the foundation of the day after tomorrow. If the spleen and stomach are weak and the transportation and transformation are abnormal, Poria cocos can help them restore the power of transportation and transformation, increase appetite and improve digestion. In addition, Poria cocos also have the ability to calm the mind and calm the mind. For those with heart palpit Therefore, Poria cocos plays a key role in the regulation of the functions of the human viscera, maintaining the balance of yin and yang and promoting health.