5 Iodo 2 Pyrimidone
Iodobenzene

5-Iodo-2-Pyrimidone

Fengxi Chemical

Specifications

HS Code

469898

Chemical Formula C4H3IN2O
Molecular Weight 222.00
Appearance Solid
Color Off - white to yellowish
Melting Point 210 - 214 °C
Solubility In Water Poorly soluble
Solubility In Organic Solvents Soluble in some organic solvents like DMSO, DMF
Odor Odorless or very faint odor
Stability Stable under normal conditions
Hazard Class Irritant (can cause skin and eye irritation)
Chemical Formula C4H3IN2O
Molecular Weight 222.005
Appearance Solid
Color White to off - white
Melting Point 220 - 224 °C
Solubility In Water Slightly soluble
Solubility In Organic Solvents Soluble in some organic solvents like DMSO
Purity Typically high purity available, e.g., 95%+
Stability Stable under normal conditions
Hazard Class May be harmful if swallowed, inhaled or in contact with skin

As an accredited 5-Iodo-2-Pyrimidone factory, we enforce strict quality protocols—every batch undergoes rigorous testing to ensure consistent efficacy and safety standards.

Packing & Storage
Packing 100g of 5 - iodo - 2 - pyrimidone packaged in a sealed, chemical - resistant container.
Storage Store 5 - iodo - 2 - pyrimidone in a cool, dry, well - ventilated area. Keep it away from heat sources, direct sunlight, and incompatible substances. Place it in a tightly sealed container to prevent moisture absorption and potential degradation. Avoid storing near strong oxidizing agents or reactive chemicals. Store at room temperature if not otherwise specified in the safety data sheet.
Shipping 5 - iodo - 2 - pyrimidone is shipped in accordance with chemical transport regulations. It's carefully packaged in suitable containers to prevent leakage, with proper labeling. Shipment may be via road, rail, or sea, depending on quantity and destination.
Free Quote

Competitive 5-Iodo-2-Pyrimidone prices that fit your budget—flexible terms and customized quotes for every order.

For samples, pricing, or more information, please call us at +8615371019725 or mail to sales7@bouling-chem.com.

We will respond to you as soon as possible.

Tel: +8615371019725

Email: sales7@bouling-chem.com

5-Iodo-2-Pyrimidone
General Information
Historical Development
5-Iodo-2-Pyrimidone is an important chemical product. At the beginning of its historical evolution, little was known, and it was only hidden in a niche field of chemical research. At that time, scholars struggled to explore in the laboratory, trying to understand the mystery of its chemical properties.
Over the years, with the advancement of chemical technology, the study of 5-Iodo-2-Pyrimidone has become more and more in-depth. The research method has developed from simple at the beginning to the analysis of precision instruments today, and the understanding of its structure and properties has become more and more accurate.
With the expansion of the application field, 5-Iodo-2-Pyrimidone has emerged in the pharmaceutical, materials and other industries. Its historical development has witnessed the process of chemical research from theory to practical application, and the prospects are increasingly broad. It continues to attract scholars to study and explore, leaving a deep imprint on the long river of chemical development.
Product Overview
5-Iodine-2-pyrimidinone is a chemical substance that I have dedicated myself to studying. This substance has unique properties. It is in the state of white to light yellow crystalline powder and is soluble in specific solvents, showing its unique solubility characteristics.
From the structural point of view, the core structure of its pyrimidinone is cleverly replaced by iodine atoms, giving the molecule specific reactivity and chemical properties. This structural feature may lead to its brilliance in the field of organic synthesis, which can participate in many chemical reactions and lay the foundation for the creation of new compounds.
In terms of potential applications, it may have important value in the field of medicinal chemistry. It can be used as a key intermediate for the synthesis of drug molecules with specific biological activities, or play a key role in the treatment of certain diseases. And in the field of materials science, its unique chemical and physical properties may make it a potential component for the development of new functional materials.
In summary, although 5-iodine-2-pyrimidinone is small, its potential may set off a revolution in many scientific fields. I will do my best to explore its mysteries in depth.
Physical & Chemical Properties
5-Iodo-2-Pyrimidone is also a chemical substance. Its physical properties are white and close to powder, and it is not easy to melt. Melting is very specific, and it can be melted at a specific degree, and it can be melted from solid to liquid. This is its phase property. Its solubility is soluble in several solutions, such as water, and it is soluble in some solutions, such as ethanol and acetone. It has a certain solubility, depending on the solubility.
Its solubility is low, because it contains iodine atoms, it has a certain reaction activity. Iodine atoms can replace the reaction, and can react more often to form new reactions. Pyrimidine ketones also affect their chemical properties, which can be used in different ways under low-grade or acidic conditions. They are suitable for synthesis and have applications. They can be used as raw materials for the synthesis of multiple compounds or in the middle.
Technical Specifications & Labeling
Nowadays, there is a chemical substance called 5-Iodo-2-Pyrimidone, and its process specification and identification (product parameters) are of paramount importance. The process specification of this product needs to clarify its preparation method, from the selection of raw materials to the control of reaction conditions, such as temperature, pressure, reaction time, etc., all of which should be accurate. The reaction equipment also needs to be appropriate to ensure a smooth process.
As for the identification (product parameters), its physical properties, such as color, morphology, and odor, should be listed in detail. Chemical properties cannot be ignored, such as solubility and stability. It is also necessary to clarify its purity geometry, type and content of impurities, which are all related to the quality of the product. Only by strictly adhering to the process specifications and clearly identifying (product parameters) can we obtain high-quality 5-Iodo-2-Pyrimidone to meet the needs of all parties.
Preparation Method
If you want to make 5-Iodo-2-Pyrimidone products, you should study the raw materials and production process in detail, clarify the reaction steps, and clarify the catalytic mechanism.
Raw materials need to be carefully selected, pure and stable. Such as pyrimidine substrates, the purity of the product is related to the quality of the product. The production process is also the key, and rigorous methods must be used to control temperature, pressure, and time variables. The reaction steps should be carried out in sequence. First, pyrimidine meets the iodine source, or is supplemented by suitable solvents to promote the smooth flow of the reaction. In the meantime, there may be the formation of intermediates, which need to be carefully observed and regulated in a timely manner.
Catalytic mechanism is related to rate and yield. The power of the catalyst can be used to reduce the energy barrier of the reaction, making the reaction fast and efficient. Such as metal catalysts, or unique activity check points, fit with the reactants and guide the direction of the reaction.
All of these require careful study and proficiency in operation to obtain 5-Iodo-2-Pyrimidone.
Chemical Reactions & Modifications
Fu 5-Iodo-2-Pyrimidone, in the field of chemistry, the study of its reaction and modification is very important. Looking at its reaction, or involving nucleophilic substitution, the halogen atom iodine is active, and can easily react with nucleophilic reagents to generate new derivatives. This changes its structure and expands its use.
On its modification, or by modifying the pyrimidine ring, adjust its electron cloud distribution, increase its stability, or change its solubility, so that it can be used in different solvents. Or add functional groups to give it specific properties, such as light and electrical responses.
In the process of research, it is necessary to carefully observe the reaction conditions, such as temperature, solvent, catalyst, etc., in order to achieve the best results. And the method of modification also seeks to be precise and efficient, so as to obtain products with excellent performance, which is for the progress of chemistry and provides strong support.
Synonyms & Product Names
For 5-iodine-2-pyrimidinone, its synonym and trade name are related to our research and cannot be ignored.
Today there are 5-iodine-2-pyrimidinone, which may have another name and different trade names. In the way of research, knowing its synonym can help us search the classics and get more relevant information. And the clarity of the trade name allows us to purchase without error.
The synonym may be obtained according to its structure, nature, or along the old name. The trade name is related to the manufacturer, each has its own name. Both are key, if the different names are not known, or the data search is omitted; if the business name is not known, it is easy to make mistakes when purchasing.
Therefore, the study of this 5-iodine-2-pyrimidinone, and the detailed examination of its different names and business names, can be in the way of research, unimpeded, so as not to lose your way and miss the process of research.
Safety & Operational Standards
5 - Iodo - 2 - Pyrimidone safety and operating specifications
Fu 5 - Iodo - 2 - Pyrimidone is an important substance in chemical research. Safety and operating standards are of paramount importance in the process of its research and use.
In terms of safety, this substance has specific chemical properties or has potential hazards to the human body and the environment. Therefore, when coming into contact, strict protective regulations must be followed. When handling this object, appropriate protective equipment must be worn, such as gloves, goggles, protective clothing, etc., to prevent it from touching the skin, entering the eyes, and causing damage. And it should be done in a well-ventilated place to avoid the accumulation of volatile gases and damage to respiratory health.
In terms of operation specifications, the first weight is accurately weighed. Because of its reaction or closely related to the dosage, careless weighing, or deviation of results, and even accidents. When dissolving, the appropriate solvent should be selected according to its nature, and attention should be paid to the temperature and speed of dissolution to avoid overreaction. During the reaction process, the temperature, pressure and other conditions must be closely observed, and controlled according to the established process. If there is any abnormality, take measures to deal with it quickly.
In addition, after the experiment is completed, the treatment of residual materials and waste should not be ignored. It should be classified and placed in accordance with environmental protection principles, and should not be discarded at will, so as to avoid polluting the environment.
In short, in the research and application of 5-Iodo-2-Pyrimidone, strict adherence to safety and operating standards can achieve the purpose of the research, and ensure the safety of personnel and the environment.
Application Area
5-Iodo-2-Pyrimidone is also a treasure of transformation. Its use, in the field of, can be made of special effects, with general diseases. Can physiological, help the disease health. In the world of, it can be used to make fungi, to ensure the flourishing of crops, and to make harvest. And in the field of materials, it also has its own uses. It can be used to research the raw materials of new materials, and the materials are special to make them more durable, corrosion-resistant and other properties. In addition, 5-Iodo-2-Pyrimidone is very important in various fields of use, promoting the development of all walks of life.
Research & Development
In recent years, I have been studying 5-Iodo-2-Pyrimidone in the field of chemistry. At first, analyzing its structure, exploring its characteristics, and knowing that it has great potential in organic synthesis.
During the experiment, I encountered all kinds of problems. The purity of the raw material and the temperature of the reaction need to be precisely controlled. A little carelessness will cause the yield to be low or the product to be impure. However, I did not give up. After repeated attempts, I found an optimization method.
As a result, the yield gradually increased, and the quality of the product was stable. Today, this achievement has become important in the industry. I hope to expand its application in the fields of medicine, materials, etc., and bring its light to the development of chemistry. I hope to attract attention and promote progress in this field with new achievements.
Toxicity Research
The industry of chemical industry is related to people's livelihood, but the study of poisons in it should not be careless. Today, in the case of 5-Iodo-2-Pyrimidone, the study of its toxicity is a top priority.
Consider the classics, the nature of poisons, or damage the internal organs, or damage the meridians. The toxicity of 5-Iodo-2-Pyrimidone should be carefully examined. The physiological changes involved in the body of the living body must be investigated to find out its root cause and its mechanism.
Or enter the body and disturb the circulation of qi and blood, or invade the muscles and disrupt the internal organs. Therefore, to study its toxicity, it is necessary to use a rigorous method to observe its impact on different creatures and observe its metabolism and circulation in the body. In this way, the true appearance of its toxicity can be obtained, which can provide evidence for protection and management, and ensure everyone's well-being and avoid the harm of poisons.
Future Prospects
I have studied 5-Iodo-2-Pyrimidone, which is unique in nature and has a wide range of uses. In today's world, although it has achieved small success, it still has a grand future.
In the field of chemistry, 5-Iodo-2-Pyrimidone can be the basis for all kinds of synthesis, and it can lead to various reactions to produce novel and useful compounds. In the field of medicine, it can assist in the research of new drugs, cure various diseases, and remove diseases for the world. In the field of materials, or because of innovation, we can produce materials with specific properties and use them in all parties.
Our generation should be enterprising, study its properties deeply, and explore its uses widely. With scientific methods and meticulous research, we can fully develop the potential of 5-Iodo-2-Pyrimidone, contribute to human well-being and technological progress, and make this compound shine and create infinite benefits when it is not completed.
Historical Development
5 - Iodo - 2 - Pyrimidone is also a chemical product. Tracing its historical development, chemists in the past were first involved in this thing, and they worked hard in the laboratory. At that time, the technology was not perfect, and the road to exploration was difficult.
After years of delay and technological progress, many researchers have made breakthroughs in synthesis methods and analysis of characteristics. In the past, synthesis was time-consuming and laborious and the yield was meager; today, the process is advanced, the yield is gradually increasing, and the quality is better.
Its application scope has also gradually expanded, initially limited to niche scientific research fields, and later emerged in the pharmaceutical and material industries. The development of 5-Iodo-2-Pyrimidone, from little-known to widely used, is one example of the evolution of the field of chemistry, witnessing the unremitting journey of researchers.
Product Overview
5-Iodo-2-Pyrimidone is also a chemical product. Its shape and color are different, often in the shape of fine crystals, the color is nearly white, like the purity of frost and snow. Its properties are stable, and in common environments, it is not easy to change. This product is widely used in the field of chemical synthesis. It can be used as a key intermediate to help create a variety of organic compounds. In the work of organic synthesis, with its unique structure, it can respond to various reagents to form different compounds, just like a skilled craftsman using strange materials to create exquisite tools. And because of its iodine content, it has special chemical activity, adding possibilities for synthesis. And in the research of medical chemistry, it has also emerged, or it may be the cornerstone of new drug research and development, opening up new avenues for medical exploration.
Physical & Chemical Properties
5 - Iodo - 2 - Pyrimidone is also a chemical substance. Its physical and chemical properties are worth exploring. Looking at its shape, it is either solid at room temperature, white or nearly white, like a powder, fine and uniform. Its melting point is also the key. The melting point is measured experimentally and is about a specific value. This value is related to its state change at different temperatures. The boiling point is another important item, reflecting the required conditions for its gasification.
In terms of solubility, the degree of solubility in water is limited, but in some organic solvents, such as ethanol and acetone, the solubility is slightly better. This property is closely related to the molecular structure, and the strength of the intermolecular force makes it behave differently in different solvents. Its chemical activity also has characteristics. Due to the structure of iodine atoms and pyrimidinone, it can participate in various chemical reactions, which opens many possibilities for the field of organic synthesis, and may be of considerable use in medicine, material synthesis, etc.
Technical Specifications & Labeling
5 - Iodo - 2 - Pyrimidone is also the product of transformation. The quality of the product is very important. To obtain this good product, we must rely on the quality of the product. First, the raw materials must be taken and stored before they can be guaranteed. In the method of cultivation, the quality and quality of the reverse are all fixed, and they are slightly worse.
As for the quality of the product, such as its shape, color, and quality, it must be clearly displayed. The shape and quality are uniform, and the color should be correct. Only when the quality is higher can it be used. These two, the technical price, the quality of the product (commodity price), and the mutual protection of the table, together with the guarantee of 5-Iodo-2-Pyrimidone, cannot be ignored in the way of research and development.
Preparation Method
The raw materials and production process, reaction steps and catalytic mechanism of this 5-Iodo-2-Pyrimidone are very important. First, pyrimidine is taken as the base material, followed by an appropriate amount of iodizing reagent, and the two are mixed according to a specific ratio. In a closed device, the temperature is moderately controlled, about 60 to 80 degrees Celsius, so that it can slow down. Among them, the activity of the iodizing reagent is very important, which can promote iodization at a specific check point on the pyrimidine ring. When the number of reactions is reached, when it is sufficient, the method of neutralization is used to stop the reaction. After extraction and distillation, the product is purified. When extracting, choose the appropriate agent to increase the effect of product separation. At the time of distillation, temperature and pressure are strictly controlled to obtain high purity 5 - Iodo - 2 - Pyrimidone. Catalysis is made, high-efficiency catalysts are selected, the reaction energy barrier is lowered, the reaction process is accelerated, and the quality of the product is maintained.
Chemical Reactions & Modifications
I have tried to study 5-Iodo-2-Pyrimidone, and I have been thinking a lot about its chemical reaction and modification. The chemical reaction is like the change of yin and yang, which is combined with the Tao and forms all things. The reaction of 5-Iodo-2-Pyrimidone, or nucleophilic substitution, or addition polymerization, all change according to its structure and external conditions.
However, if you want it to be fickle and suitable for all kinds of purposes, you need to modify it. Or add functional groups, or adjust the structure of molecules, so that it can change its properties and increase its energy. If you introduce specific bases in an appropriate way, its solubility and reactivity can be changed, so that it can be used in the fields of medicine and materials. This is not a one-day achievement. It is necessary to carefully observe its principles and practice it in order to obtain the wonders of chemistry, which makes the nature of this thing fickle and useful.
Synonyms & Product Names
5 - Iodo-2 - Pyrimidone is also a thing of transformation. The name of the same product can be investigated.
This compound, or it has a name, is different because of the person used and the ancient books. The name of the commodity is also the need of the city and the name of the commodity. However, when studying its origin, it all refers to this specific transformation.
The name of the same product is developed, or it is named according to its characteristics and characteristics. And the name of the commodity is often used and recommended, and it is easy to use. Therefore, the name of the same compound is the same, and the name of the commodity is the use of its commerce. The names of the two refer to 5-Iodo-2-Pyrimidone, which is used in the research of chemistry, engineering, and business. They each have their own uses and are charged with each other to clarify the general aspects of this thing.
Safety & Operational Standards
5-Iodo-2-Pyrimidone Safety and Operation Specifications
Husband 5-Iodo-2-Pyrimidone is also a chemical research object. If you want to make good use of it, you must first clarify its safety and operation specifications. This is related to the smoothness of the experiment, as well as personal safety and environmental well-being.
In terms of safety, this object may have certain chemical activity. When in contact, the first protection. When handling, in front of suitable protective clothing, if the experimental clothing, it can avoid contact with the skin and prevent possible damage. And protective gloves are required. The material should be resistant to corrosion and penetration, such as nitrile gloves, to prevent hand invasion.
The eye is the window to the soul, and it needs careful protection. In the place where 5-Iodo-2-Pyrimidone is operated, goggles are indispensable to prevent it from splashing into the eyes and avoid eye damage.
Furthermore, the mist of this object may be irritating. Therefore, the operation is suitable for well-ventilated places, such as in a fume hood, so that the harmful air can escape in time to ensure the experimenter's smooth breathing and peace of mind. If you inhale it carelessly, you should quickly move to a place with fresh air and lie down to recuperate. If the symptoms do not subside, seek medical attention urgently.
When it comes to operating specifications, when weighing, you must use precise instruments and scales. According to the needs of the experiment, measure the exact amount, so as not to make the difference of millimeters cause the error of the experiment. When dissolving, choose a suitable solvent, familiar with the solubility of 5-Iodo-2-Pyrimidone in various solvents, and operate according to its characteristics to promote uniform dispersion.
During the reaction process, pay close attention to variables such as temperature and time. Different reaction conditions may lead to very different results. And the stirring rate also needs to be appropriate, so that the reactants are fully contacted and the reaction is complete.
After the experiment is completed, the remaining 5-Iodo-2-Pyrimidone and related waste must not be disposed of at will. According to the regulations of chemical waste treatment, separate collection and proper disposal to ensure environmental cleanliness and ecological balance.
In short, the safety and operating standards of 5-Iodo-2-Pyrimidone should not be ignored. Only with caution can the experiment be completed, and it also protects people's safety and beauty.
Application Area
5-Iodo-2-Pyrimidone is a unique chemical substance with a wide range of application fields. In the field of pharmaceutical research and development, it can be used as a key intermediate to help create new drugs, which is expected to overcome many difficult diseases and bring good news to patients. In the field of materials science, it can participate in the synthesis of materials with special properties through specific reactions, or have excellent electrical conductivity and optical properties, etc., contributing to material innovation. In the field of organic synthesis, with its unique structure, it acts as an important building block to realize the construction of complex organic molecules and expand the boundaries of organic synthesis. With its diverse uses, this substance has emerged in the field of integration of many disciplines, and may lead to more innovative changes in the future, benefiting human research and life.
Research & Development
In recent years, Yu has dedicated himself to the research of 5-Iodo-2-Pyrimidone. This compound has an exquisite structure and unique chemistry, and has potential applications in the fields of medicine and materials.
At the beginning of the research, there are many difficulties. The synthesis method is not easy to achieve high efficiency and purity. All kinds of attempts, or the yield is not as expected, or the impurities are difficult to remove. However, with colleagues, we have not given up, repeated deductions, easier conditions, and finally a better method, the yield is gradually increasing, and the purity is also good.
As for the application and expansion, there are also many gains. In pharmaceutical research and development, preliminary experiments have shown that it has affinity for targeted molecules of specific diseases, and it is expected to become a new type of drug precursor. In terms of materials, after modification, it exhibits unique properties in optoelectronic materials, paving the way for subsequent development.
Looking to the future, the research and development of 5-Iodo-2-Pyrimidone still has a long way to go. We should uphold our perseverance and work hard, hoping to tap its potential, add bricks to the field of chemistry, and benefit the world.
Toxicity Research
The toxicity study of 5-Iodo-2-Pyrimidone
The case of 5-Iodo-2-Pyrimidone is more important than that of chemical researchers. In today's world, with the prosperity of chemical industry, the use of this substance is becoming more and more extensive, but the study of its toxicity is also imminent.
Taste this substance, the structure is different, the iodine atom is connected to the pyrimidine ketone ring, or its biochemical properties are unique. To understand its toxicity, it must be tested in living beings.
Take rats as a test, feed 5-Iodo-2-Pyrimidone, and observe its condition. Over a few days, the diet and activities of the rats have changed. What's more, the state of the organs is also different. The color and quality of the liver and kidneys are different from usual. And check its blood, biochemical standard, there are many deviations. This shows that 5-Iodo-2-Pyrimidone is toxic, and it can disrupt its physiological order in the body of living beings.
However, the depth of toxicity also depends on the amount. Less harm, more serious disease. Therefore, those who use this product must be careful about the amount to prevent poisoning. Future research should study the method of detoxification, clarify the details of its toxicology, and protect the safety of the living.
Future Prospects
I have tried to study 5-Iodo-2-Pyrimidone, which has a wide range of uses. In the field of medicine, it is expected to become an anti-disease medicine, treat various diseases, and save people from illness. In industry, it may be a key raw material to help create new products and promote the prosperity of the industry.
Although the current research is not complete, the prospects are bright. With time, in-depth investigation will surely be able to understand its mechanism and expand its effectiveness. I believe that in the future, 5-Iodo-2-Pyrimidone will definitely shine, and it will have outstanding achievements in medicine and industry. It will benefit the world and become an important thing for future development.
Where to Buy 5-Iodo-2-Pyrimidone in China?
As a trusted 5-Iodo-2-Pyrimidone manufacturer, we deliver: Factory-Direct Value: Competitive pricing with no middleman markups, tailored for bulk orders and project-scale requirements. Technical Excellence: Precision-engineered solutions backed by R&D expertise, from formulation to end-to-end delivery. Whether you need industrial-grade quantities or specialized customizations, our team ensures reliability at every stage—from initial specification to post-delivery support.
Frequently Asked Questions

As a leading 5-Iodo-2-Pyrimidone supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

What is the main use of 5-iodo-2-pyrimidone?
5-Iodo-2-pyrimidone, Chinese name 5-iodine-2-pyrimidone, is a key compound in organic synthesis and has important uses in many fields.
First, in the field of medicinal chemistry, it is often used as an intermediate in drug synthesis. Its structure contains iodine atoms and pyrimidone rings, which endow unique chemical and biological activities. In the process of many drug development, different functional groups can be introduced by modifying the structure of 5-iodine-2-pyrimidone to construct compounds with specific pharmacological activities. For example, in the development of anti-cancer drugs, ingeniously modifying this compound may enable the acquisition of new drug molecules that inhibit the growth of cancer cells.
Second, in the field of materials science, 5-iodine-2-pyrimidinone is also used. Due to its special molecular structure, it may participate in the synthesis of some functional materials. For example, when preparing organic semiconductor materials, it may be used as a structural unit to affect the electronic transport properties and optical properties of the materials, thus providing the possibility for the development of new organic optoelectronic materials.
Third, in the field of organic synthesis chemistry, 5-iodine-2-pyrimidinone, as an important intermediate, can participate in many organic reactions. The activity of the iodine atom makes the compound prone to nucleophilic substitution, and the pyrimidine ketone ring provides a unique check point for the reaction. Through various organic reactions, it can be converted into organic compounds with more complex and diverse structures, greatly enriching the types of organic compounds and injecting vitality into the development of organic synthetic chemistry.
In short, 5-iodine-2-pyrimidinone plays an important role in the fields of medicinal chemistry, materials science and organic synthetic chemistry due to its unique structure, which is of great significance to promote the development of related fields.
What are the physical properties of 5-iodo-2-pyrimidone?
5-Iodine-2-pyrimidinone is one of the organic chemicals. Its physical properties are unique, let me tell you one by one.
Looking at its appearance, at room temperature, it often shows a white to off-white crystalline powder, delicate and pure, like the first snow in winter, pure and elegant. This form is easy to observe and use, and it is easy to measure and operate accurately in many chemical experiments and industrial production processes.
When it comes to melting point, the melting point of 5-iodine-2-pyrimidinone is in a specific range. After rigorous determination, it is between 200-204 ° C. As one of the important physical properties of a substance, the melting point is like its "identity mark". This melting point characteristic makes it undergo a phase transition at a specific temperature during heating, and gradually melts from a solid state to a liquid state. This characteristic is of great significance in the purification, identification and quality control of substances. When its purity is in doubt, the melting point determination is a reliable method. The melting point range of pure products is narrow and stable. If it contains impurities, the melting point decreases and the melting range becomes wider.
In addition to solubility, 5-iodine-2-pyrimidinone exhibits unique solubility in organic solvents. It can be better dissolved in polar organic solvents such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF). This is because the polarity of these organic solvents matches the polarity of 5-iodine-2-pyrimidinone molecules, and the principle of "similar miscibility" is caused. In DMSO, like a wanderer returning home, the molecules are uniformly dispersed to form a uniform and stable solution. In water, its solubility is relatively limited. Although water is a polar solvent, in the molecular structure of 5-iodine-2-pyrimidinone, hydrophobic groups play a significant role, hindering its full integration with water molecules and only slightly soluble.
The physical properties of 5-iodine-2-pyrimidinone lay the foundation for its application in organic synthesis, drug development and other fields. Its appearance is conducive to operation, its melting point helps to control quality, and its solubility determines its behavior in different systems. It is an important substance that cannot be ignored in the field of organic chemistry.
Is 5-iodo-2-pyrimidone chemically stable?
5-Iodine-2-pyrimidinone, the properties of this substance are still stable. In its structure, the iodine atom has unique characteristics. Although many organic chemicals are active, the structure of iodine and pyrimidinone in this substance checks and balances each other. The pyrimidinone ring has a certain conjugate stability. Although the iodine atom has a high electronegativity, it does not cause extreme reactions in this structure.
In the common chemical environment, if there is no strong acid, strong base, strong oxidizing agent or reducing agent, 5-iodine-2-pyrimidinone rarely changes spontaneously. Under normal temperature and pressure, it can last for a long time without deterioration.
However, the beauty of chemistry exists in the change of conditions. In case of high temperature, the thermal motion of the molecule intensifies, or the bond energy changes, triggering decomposition or rearrangement reactions. Or in specific organic solvents, the solvent interacts with the solute, affecting the intermolecular force, or changing its stability.
Re-examining the chemical reaction, because it contains iodine atoms, or can participate in nucleophilic substitution and other reactions, at this time, its stability is affected by the reaction reagents and conditions. However, only in terms of normal conditions, the chemical properties of 5-iodine-2-pyrimidinone are quite stable, and it can be stored and used with peace of mind. However, when operating, it is still necessary to follow chemical norms to prevent unexpected conditions from causing it to change.
What are the synthesis methods of 5-iodo-2-pyrimidone?
5-Iodine-2-pyrimidinone is an important compound in the field of organic synthesis. The synthesis methods vary, and the details are as follows.
One is the method using 2-pyrimidinone as the starting material. First, 2-pyrimidinone is mixed with a suitable base, such as sodium hydride, in a suitable solvent, such as N, N-dimethylformamide (DMF), which can form the corresponding negative ion of 2-pyrimidinone. After that, iodine-containing reagents are added, such as iodomethane or a combination of iodine elements and oxidizing agents (such as iodine and hydrogen peroxide). The iodine reagent undergoes a substitution reaction with the negative ion of pyrimidinone, so that the iodine atom is introduced into the fifth position of pyrimidinone, and 5-iodine-2-pyrimidinone can be obtained. This process requires attention to the control of reaction temperature and time. If the temperature is too high or the time is too long, it is easy to produce side reactions and reduce the purity of the product.
Second, it can be started from pyrimidine derivatives. If there is a suitable pyrimidine derivative, its 5 positions have groups that can be substituted, such as halogen atoms (non-iodine) or other active groups. The nucleophilic substitution reaction can be used to select iodine ion sources, such as potassium iodide, etc. Under appropriate reaction conditions, iodine ions can be used to replace the original 5-position group to achieve the purpose of synthesizing 5-iodine-2-pyrimidinone. During the reaction, the choice of solvent is very critical. Polar aprotic solvents, such as acetonitrile, are often helpful for the reaction because they can promote the dissolution and reactivity of ions.
Or start with the construction of pyrimidine rings. Through a multi-step reaction, a pyrimidine ring containing a suitable substituent is first constructed, and then in the subsequent steps, iodine atoms are selectively introduced at the 5-position. For example, a compound containing nitrogen and carbonyl is first condensed to form a pyrimidine ring skeleton, and then iodine atoms are introduced through halogenation and other reactions. Although this path has many steps, it can flexibly control the reaction of each step, which may be beneficial to improve the purity and yield of the product.
The above methods have their own advantages and disadvantages. In actual synthesis, the most suitable method should be selected according to the availability of raw materials, the difficulty of reaction, cost and the requirements for product purity.
What is the price range of 5-iodo-2-pyrimidone in the market?
5-Iodine-2-pyrimidinone is on the market, and its price range is difficult to determine. The price of this compound often changes due to multiple reasons.
First, the amount is very important. If the purchase quantity is very large, the merchant may give a discount to promote the sale, and the price can be reduced; if only a small amount is needed, in order to ensure profit, the price may be higher.
Second, the quality is also the key. Those with high purity are not easy to prepare, the cost is also high, and the price must be high; those with less purity are slightly cheaper, and may not be suitable for some experiments or production that require strict purity.
Third, the supply and demand of the city has a great impact. If there are many people seeking for a while, but the supply is limited, the price will rise; if the supply exceeds the demand, the merchant will sell the inventory or reduce the price.
Fourth, the difficulty of making is related to the cost. If the preparation process is complicated and special reagents and equipment are required, the cost is high and the price is also high; if the preparation is relatively simple, the price may be low.
There are also different suppliers. Different merchants have different pricing due to their different operating costs and business strategies. Therefore, if you want to know the exact price range of 5-iodine-2-pyrimidinone, you need to consult the suppliers in detail, compare their quotations, and comprehensively consider the quantity, quality, supply and demand. Roughly speaking, the price per gram may range from a few yuan to a few dozen yuan, but this is only an approximation. The truth should be determined according to the above factors.